Journal articlePhysics Letters Section B Nuclear Elementary Particle and High Energy Physics · September 1, 2026
A first search at the LHC for a new heavy resonance decaying to a top quark and a neutral scalar boson ϕ in the fully hadronic final state is presented, where the ϕ boson is identified by its decay into a bottom quark-antiquark pair. The search is focused ...
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Journal articlePhys Rev Lett · August 28, 2026
Evidence of the production of two Z bosons and a photon in proton-proton collisions is reported for the first time in CMS. The analysis uses data collected by the CMS experiment between 2016 and 2018 at a center-of-mass energy of 13 TeV, corresponding to a ...
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Journal articlePhys Rev Lett · August 21, 2026
The long-range collective flow of particles produced in oxygen-oxygen (O+O) and neon-neon (Ne+Ne) collisions is measured with the CMS detector at the CERN LHC. The data samples were collected at a center-of-mass energy per nucleon pair of 5.36 TeV, with in ...
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Journal articlePhys Rev Lett · August 14, 2026
Energetic quarks and gluons traversing a hot and dense quark-gluon plasma deposit energy and momentum into the medium before hadronizing to collimated sprays of particles, known as jets. This energy-momentum deposition is expected to produce medium respons ...
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Journal articleJournal of High Energy Physics · August 1, 2026
The single top quark t-channel production cross section is measured in proton-proton collisions at the CERN LHC at s=5.02 TeV, using data recorded with the CMS detector in 2017, corresponding to an integrated luminosity of 302 pb−1, and resultin ...
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Journal articleEuropean Physical Journal C · July 1, 2026
A search is presented for massive narrow-width resonances in the mass range of 1–4.5TeV, decaying into pairs of Higgs bosons (HH). The search uses proton–proton collision data at a center-of-mass energy of 13TeV collected with the CMS detector at the CERN ...
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Journal articleJ Appl Clin Med Phys · April 2025
This article investigates the performance of a commercial BeO optically stimulated luminescent (OSL) dosimetry system (myOSLchip, RadPro GmbH International, Remscheid, Germany) through the application of the commissioning framework for luminescent dosimete ...
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Journal articleJ Appl Clin Med Phys · April 2025
The purpose of this Medical Physics Practice Guideline (MPPG) is to describe the minimum level of medical physics support deemed prudent for the practice of linear-accelerator, photon-based (linac) stereotactic radiosurgery (SRS), and stereotactic body rad ...
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Journal articleBioengineering (Basel) · March 29, 2025
(1) Objective: To develop and implement an in-house software quality management (ISQM) program to ensure the continuous, consistent quality of in-house software products. (2) Methods: The ISQM program consists of two key components: quality assurance (QA) ...
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Journal articlePhys Med Biol · November 14, 2024
Objective.Artificial intelligence (AI) based treatment planning tools are being implemented in clinic. However, human interactions with such AI tools are rarely analyzed. This study aims to comprehend human planner's interaction with the AI planning tool a ...
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Journal articleJ Radiosurg SBRT · 2022
OBJECTIVE: To assess dosimetric variation caused by breast deformation in breast radiosurgery based on deformable image registration. METHODS: This study included 30 patients who were treated in the prone position for preoperative partial breast radiosurge ...
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Journal articleAdv Radiat Oncol · 2021
PURPOSE: The machine learning-based automated treatment planning (MLAP) tool has been developed and evaluated for breast radiation therapy planning at our institution. We implemented MLAP for patient treatment and assessed our clinical experience for its p ...
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Journal articleJ Radiosurg SBRT · 2020
OBJECTIVE: To analyze and evaluate accuracy and efficiency of IGRT process for preoperative partial breast radiosurgery. METHODS: Patients were initially setup with skin marks and 5 steps were performed: (1) Initial orthogonal 2D kV images, (2) pre-treatme ...
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Journal articleTechnol Cancer Res Treat · January 1, 2019
PURPOSE: To develop an automated optimization program to generate optimal beam settings for whole-breast radiation therapy driven by clinically oriented goals. MATERIALS AND METHODS: Forty patients were retrospectively included in this study. Each patient' ...
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Journal articleFront Oncol · 2019
Purpose: To develop an automatic treatment planning system for whole breast radiation therapy (WBRT) based on two intensity-modulated tangential fields, enabling near-real-time planning. Methods and Materials: A total of 40 WBRT plans from a single institu ...
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Journal articleClin Transl Radiat Oncol · October 2017
BACKGROUND: Following breast-conserving surgery and post-operative 3D-conformal accelerated partial breast irradiation (APBI), suboptimal cosmetic results have been reported. Preoperative radiation delivery to the intact tumor enables better target visuali ...
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Journal articleMed Phys · June 2016
PURPOSE: To enable near-real-time (<20sec) and interactive planning without compromising quality for whole breast RT treatment planning using tangential fields. METHODS: Whole breast RT plans from 20 patients treated with single energy (SE, 6MV, 10 patient ...
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Journal articleInt J Radiat Oncol Biol Phys · July 15, 2015
PURPOSE: Women with biologically favorable early-stage breast cancer are increasingly treated with accelerated partial breast radiation (PBI). However, treatment-related morbidities have been linked to the large postoperative treatment volumes required for ...
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Journal articleJ Appl Clin Med Phys · January 8, 2015
The purpose of this study was to compare dosimetric parameters of treatment plans among four techniques for preoperative single-fraction partial breast radiotherapy in order to select an optimal treatment technique. The techniques evaluated were noncoplana ...
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Journal articleJournal of Applied Clinical Medical Physics · January 1, 2015
The purpose of this study was to compare dosimetric parameters of treatment plans among four techniques for preoperative single-fraction partial breast radiotherapy in order to select an optimal treatment technique. The techniques evaluated were noncoplana ...
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Journal articlePract Radiat Oncol · 2015
PURPOSE: Diffusion of accelerated partial breast irradiation into clinical practice is limited by the need for specialized equipment and training. The accessible external beam technique yields unacceptable complication rates, likely from large postoperativ ...
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Journal articleMed Dosim · 2014
The purpose is to dosimetrically compare the following 3 delivery techniques: 3-dimensional conformal radiation therapy (3D-CRT), intensity-modulated arc therapy (IMRT), and volumetric-modulated arc therapy (V-MAT) in the treatment of accelerated partial-b ...
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Journal articleMed Phys · June 2013
PURPOSE: To investigate a novel Single Photon Emission Computed Tomography (SPECT) system for on-board molecular and functional imaging in partial breast radiation therapy of prone patients. METHODS: Computer-simulation studies were performed for on-board ...
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Journal articleJ Appl Clin Med Phys · January 7, 2013
The purpose of this study was to evaluate the sliced body volume (SBV) as a respiratory surrogate by comparing with the real-time position management (RPM) in phantom and patient cases. Using the SBV surrogate, breathing signals were extracted from unsorte ...
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Journal articleJournal of Applied Clinical Medical Physics · January 1, 2013
The purpose of this study was to evaluate the sliced body volume (SBV) as a respiratory surrogate by comparing with the real-time position management (RPM) in phantom and patient cases. Using the SBV surrogate, breathing signals were extracted from unsorte ...
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Journal articleFront Oncol · 2013
PURPOSE/OBJECTIVE: While our department is heavily invested in computer-based treatment planning, we historically relied on paper-based charts for management of Radiation Oncology patients. In early 2009, we initiated the process of conversion to an electr ...
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Journal articleJ Appl Clin Med Phys · July 5, 2012
American Association of Physicists in Medicine (AAPM) task group (TG) 142 has recently published a report to update recommendations of the AAPM TG 40 report and add new recommendations concerning medical accelerators in the era of image-guided radiation th ...
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Journal articleMed Phys · June 2012
PURPOSE: To investigate th applicability of the flattening filter free (FFF) to fractionated radiotherapy of head and neck cancer. METHODS: Twelve patients previously treated with IMRT were selected. A SIB protocol was chosen so that 66/54 Gy were prescrib ...
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Journal articleRadiother Oncol · May 2012
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PURPOSE: To investigate (1) dosimetric differences between plans calculated using the anisotropic analytical algorithm (AAA) and pencil beam convolution (PBC) algorithm, (2) the plan quality achieved using AAA compared to PBC based on dosimetric parameters ...
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Journal articleInt J Radiat Oncol Biol Phys · May 1, 2012
PURPOSE: To assess the impact of increasing experience with intensity-modulated radiation therapy (IMRT) after extrapleural pneumonectomy (EPP) for malignant pleural mesothelioma (MPM). METHODS AND MATERIALS: The records of all patients who received IMRT f ...
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Journal articleMed Phys · April 2012
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PURPOSE: Commercial CT-based image-guided radiotherapy (IGRT) systems allow widespread management of geometric variations in patient setup and internal organ motion. This document provides consensus recommendations for quality assurance protocols that ensu ...
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Journal articleInt J Radiat Oncol Biol Phys · January 1, 2012
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PURPOSE: Several recent series evaluating external beam accelerated partial breast irradiation (PBI) have reported adverse cosmetic outcomes, possibly related to large volumes of normal tissue receiving near-prescription doses. We hypothesized that deliver ...
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Journal articleJournal of Applied Clinical Medical Physics · January 1, 2012
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American Association of Physicists in Medicine (AAPM) task group (TG) 142 has recently published a report to update recommendations of the AAPM TG 40 report and add new recommendations concerning medical accelerators in the era of image-guided radiation th ...
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Journal articleMed Dosim · 2011
Several series evaluating external-beam partial breast irradiation (PBI) have linked negative cosmetic outcomes to large normal tissue treatment volumes. We compared patients treated with PBI whose treatment plans included only photons to those whose plans ...
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Journal articleInt J Radiat Oncol Biol Phys · December 1, 2010
PURPOSE: Intensity-modulated radiation therapy (IMRT) has the potential to reduce toxicities associated with chemoradiotherapy in the treatment of anal cancer. This study reports the results of using IMRT in the treatment of anal cancer. METHODS AND MATERI ...
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Journal articleInt J Radiat Oncol Biol Phys · September 1, 2010
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PURPOSE: To investigate the technical feasibility of volumetric modulated arc therapy (V-MAT) in the delivery of partial breast irradiation (PBI). METHODS AND MATERIALS: V-MAT and the standard, three-dimensional conformal radiotherapy (3D-CRT), were compar ...
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Journal articleMed Phys · July 2010
PURPOSE: To assess imaging dose of partial and full-angle kilovoltage CBCT scan protocols and to evaluate image quality for each protocol. METHODS: The authors obtained the CT dose index (CTDI) of the kilovoltage CBCT protocols in an on-board imager by ion ...
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Journal articleHealth Phys · May 2010
To address the lack of accurate dose estimation method in cone beam computed tomography (CBCT), we performed point dose metal oxide semiconductor field-effect transistor (MOSFET) measurements and Monte Carlo (MC) simulations. A Varian On-Board Imager (OBI) ...
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Journal articlePhys Med Biol · April 21, 2010
This work presents an investigation into the use of PRESAGE dosimeters with an optical-CT scanner as a 3D dosimetry system for quantitative verification of respiratory-gated treatments. The CIRS dynamic thorax phantom was modified to incorporate a moving P ...
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Journal articleInt J Radiat Oncol Biol Phys · March 1, 2010
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PURPOSE: Dosimetric results and treatment delivery efficiency of RapidArc plans to those of conventional intensity-modulated radiotherapy (IMRT) plans were compared using the Eclipse treatment planning system for high-risk prostate cancer. MATERIALS AND ME ...
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Journal articleInt J Radiat Oncol Biol Phys · December 1, 2009
PURPOSE: This clinical study evaluates the feasibility of using volumetric arc-modulated treatment (VMAT) for spine stereotactic body radiotherapy (SBRT) to achieve highly conformal dose distributions that spare adjacent organs at risk (OAR) with reduced t ...
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Journal articleOncology (Williston Park) · November 15, 2009
The contemporary treatment of anal cancer is combined-modality therapy with radiation therapy, fluorouracil, and mitomycin. This therapy results in long-term disease-free survival and sphincter preservation in the majority of patients. Tempering these posi ...
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Journal articleOncology · November 15, 2009
The contemporary treatment of anal cancer is combined-modality therapy with radiation therapy, fluorouracil, and mitomycin. This therapy results in long-term disease-free survival and sphincter preservation in the majority of patients. Tempering these posi ...
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Journal articlePhys Med Biol · September 7, 2009
This study investigated the integration of the Calypso real-time tracking system, based on implanted ferromagnetic transponders and a detector array, into the current process for image-guided radiation treatment (IGRT) of prostate cancer at our institution ...
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Journal articleMed Phys · May 2009
This study compares three online image guidance techniques (IGRT) for prostate IMRT treatment: bony-anatomy matching, soft-tissue matching, and online replanning. Six prostate IMRT patients were studied. Five daily CBCT scans from the first week were acqui ...
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Journal articleInt J Radiat Oncol Biol Phys · February 1, 2009
PURPOSES: To quantitatively compare two-dimensional (2D) orthogonal kV with three-dimensional (3D) cone-beam CT (CBCT) for target localization; and to assess intrafraction motion with kV images in patients undergoing stereotactic body radiotherapy (SBRT). ...
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Journal articleInt J Radiat Oncol Biol Phys · January 1, 2009
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PURPOSE: To evaluate on-board digital tomosynthesis (DTS) for patient positioning vs. two-dimensional (2D) radiography and three-dimensional cone beam (CBCT). METHODS AND MATERIALS: A total of 92 image sessions from 9 prostate cancer patients were analyzed ...
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Journal articleMed Phys · December 2008
Real-time tracking can provide high accuracy localization for a moving target and minimize the effect of motion. Simultaneous kV-MV imaging has been proposed as a real-time tracking technique by utilizing the existing kV on-board imager (OBI) and the MV el ...
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Journal articleRadiother Oncol · December 2008
BACKGROUND AND PURPOSE: In this study, we investigated IMRT QA using Statistical Process Control for the purpose of comparing the processes of patient-specific measurements and the corresponding independent computer calculations. MATERIALS AND METHODS: Poi ...
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Journal articlePhys Med Biol · September 21, 2008
The purpose of this study is two-fold: first is to investigate the process of IMRT QA using control charts and second is to compare control chart limits to limits calculated using the standard deviation (sigma). Head and neck and prostate IMRT QA cases fro ...
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Journal articleInt J Radiat Oncol Biol Phys · July 15, 2008
PURPOSE: To assess the safety and efficacy of intensity-modulated radiotherapy (IMRT) after extrapleural pneumonectomy for malignant pleural mesothelioma. METHODS AND MATERIALS: Thirteen patients underwent IMRT after extrapleural pneumonectomy between July ...
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Journal articleTechnol Cancer Res Treat · April 2008
This report describes the technique and initial experience using cone beam CT (CBCT) for localization of treatment targets in patients undergoing stereotactic body radiation therapy (SBRT). Patients selected for SBRT underwent 3-D or 4-D CT scans in a cust ...
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Journal articleInt J Radiat Oncol Biol Phys · March 15, 2008
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PURPOSE: On-board cone-beam computed tomography (CBCT) provides soft tissue information that may improve setup accuracy in patients undergoing accelerated partial breast irradiation (APBI). We used CBCT to assess the residual error in soft tissue after two ...
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Journal articlePhys Med Biol · February 7, 2008
For intermediate and high risk prostate cancer, both the prostate gland and seminal vesicles are included in the clinical target volume. Internal motion patterns of these two organs vary, presenting a challenge for adaptive treatment. Adaptive techniques s ...
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Journal articleRadiat Prot Dosimetry · 2008
In recent years, wide beam computed tomography (CT) technique has become standard in radiation oncology whereas there is little information about radiation dose assessments for the technique. A point dose measurement method was employed to assess the radia ...
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Journal articleInt J Radiat Oncol Biol Phys · October 1, 2007
PURPOSE: High-precision intensity-modulated radiotherapy demands high patient positioning accuracy. On-board digital tomosynthesis (DTS) provides three-dimensional (3D) image guidance for daily positioning with a lower imaging dose, faster acquisition, and ...
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Journal articleMed Phys · August 2007
Digital tomosynthesis (DTS) is a fast, low-dose three-dimensional (3D) imaging approach which yields slice images with excellent in-plane resolution, though low plane-to-plane resolution. A stack of DTS slices can be reconstructed from a single limited-ang ...
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Journal articleHum Gene Ther · June 2007
Optimization of adenoviral delivery to the target volume is required for adenovirus-mediated cancer gene therapy to reach its maximal potential. The purpose of these studies was to develop a model of gene expression to improve adenovirus-mediated cancer ge ...
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Journal articlePhys Med Biol · February 7, 2007
We continue our work on the development of an efficient treatment-planning algorithm for prostate seed implants by incorporation of an automated seed and needle configuration routine. The treatment-planning algorithm is based on region of interest (ROI) ad ...
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Journal articleMed Phys · February 2007
The goals of interstitial implant brachytherapy include delivery of the target dose in a uniform manner while sparing sensitive structures, and minimizing the number of needles and sources. We investigated the use of a multi-species source arrangement (192 ...
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Journal articleMedical Physics · January 1, 2007
As high‐precision 3‐D conformal radiation therapy and intensity‐modulated radiation therapy have become standard practice, radiographic imaging using kilovoltage (kV) x‐ray sources has been rapidly implemented for in‐room target localization and patient po ...
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Journal articleInt J Radiat Oncol Biol Phys · December 1, 2006
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PURPOSE: Cone-beam computed tomography (CBCT) images are currently used for positioning verification. However, it is yet unknown whether CBCT could be used in dose calculation for replanning in adaptive radiation therapy. This study investigates the dosime ...
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Journal articleMed Phys · November 2006
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To develop a quality assurance (QA) program for the On-Board Imager (OBI) system and to summarize the results of these QA tests over extended periods from multiple institutions. Both the radiographic and cone-beam computed tomography (CBCT) mode of operati ...
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Journal articleInt J Radiat Oncol Biol Phys · May 1, 2006
PURPOSE: To generate on-board digital tomosynthesis (DTS) and reference DTS images for three-dimensional image-guided radiation therapy (IGRT) as an alternative to conventional portal imaging or on-board cone-beam computed tomography (CBCT). METHODS AND MA ...
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Journal articleMedical Physics · January 1, 2005
Purpose: On‐board imager (OBI) has been implemented to improve the in‐room patient positioning. It is therefore important to establish quality assurance (QA) procedure to ensure proper functionality and operational accuracy. This report presents monthly OB ...
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Journal articlePhys Med Biol · December 21, 2003
We have developed an efficient treatment-planning algorithm for prostate implants that is based on region of interest (ROI) adjoint functions and a greedy heuristic. For this work, we define the adjoint function for an ROI as the sensitivity of the average ...
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Journal articleMed Phys · May 2003
A new type of radiographic film, EDR (extended dose range) film, has been recently become available for film dosimetry. It is particularly attractive for composite isodose verification of intensity modulated radiation therapy because of its low sensitivity ...
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Journal articleMed Phys · October 2002
Historically, there have been a variety of dosimetry protocols used for kilovoltage x-ray therapy beams with a set of conversion factors and correction factors taken from different references. Corresponding to the continued installation and use of kilovolt ...
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