Journal ArticleJAAD International · December 1, 2024
Background: Understanding health state utilities of skin diseases is essential for health economic evaluations in an era of rising health care costs. Objective: To create a catalog of utility values of chronic skin diseases among Asians. Methods: This is a ...
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Journal ArticleClin Cancer Res · November 1, 2024
PURPOSE: Sebaceous carcinoma is the third most common nonkeratinocyte skin cancer in the United States with 1,000 cases per year. The clinicopathologic features of sebaceous carcinoma and benign sebaceous neoplasms (adenomas, sebaceomas) can overlap, highl ...
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Journal ArticleJID Innov · July 2024
The image quality received for clinical evaluation is often suboptimal. The goal is to develop an image quality analysis tool to assess patient- and primary care physician-derived images using deep learning model. Dataset included patient- and primary care ...
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Journal ArticleArch Dermatol Res · June 7, 2024
Itch is a common symptom of dermatologic diseases associated with significant impairment of health-related quality of life (QoL). This study reveals disparities in itch symptom experience and itch impact on QoL. A retrospective study of patient-reported ou ...
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Journal ArticleJAMA Dermatol · May 1, 2024
IMPORTANCE: Dermatologists prescribe more oral antibiotics per clinician than clinicians in any other specialty. Despite clinical guidelines that recommend limitation of long-term oral antibiotic treatments for acne to less than 3 months, there is little e ...
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Journal ArticleJMIR Dermatol · February 7, 2024
BACKGROUND: Veterans Affairs health care systems have been early adopters of asynchronous telemedicine to provide access to timely and high-quality specialty care services in primary care settings for veterans living in rural areas. Scant research has exam ...
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Journal ArticleJAMA Dermatol · February 1, 2024
IMPORTANCE: Despite the US Food and Drug Administration's approval of adalimumab for the treatment of hidradenitis suppurativa (HS), prescription rates remain low, indicating a critical gap between evidence-based guidelines and clinical practice. Understan ...
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Journal ArticleJAMA Dermatol · February 1, 2024
IMPORTANCE: While acne is common in transgender and gender-diverse people and is associated with gender-affirming hormone therapy, little research has examined these factors and their impact in gender minority groups. OBJECTIVE: To examine the lived experi ...
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Journal ArticleJID Innov · November 2023
Relationships between cutaneous adverse effects (CAEs) and noncutaneous adverse effects (NCAEs) of melanoma immunotherapy may help identify patterns tied to distinct immunologic pathways. The objective of this study was to determine the associations betwee ...
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Journal ArticleImplement Sci Commun · October 27, 2023
BACKGROUND: Teledermatology (TD) is an evidence-based practice that may increase access to dermatologic care. We sought to use the Exploration, Preparation, Implementation, and Sustainment (EPIS) and the Reach, Efficacy, Adoption, Implementation, and Maint ...
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Journal ArticleBr J Dermatol · October 25, 2023
In this qualitative study, 21 adults living with hidradenitis suppurativa (HS) were interviewed about their healthcare experiences. Participants detailed how delay in diagnosis, lack of provider knowledge, inadequate pain management, poor access to care an ...
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Journal ArticleAnn Surg Oncol · October 2023
BACKGROUND: The optimal time to initiate adjuvant immune checkpoint inhibitors (ICI) following resection remains undefined. Herein, we investigated the impact of time to adjuvant ICI on survival in patients with stage III melanoma. METHODS: Patients with r ...
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Journal ArticleArch Dermatol Res · September 2023
This cross-sectional study aimed to examine financial toxicity among people with skin cancer using pooled National Health Interview Survey data from adults in 2011-2018. Material, behavioral, and psychological markers of financial toxicity were compared by ...
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Journal ArticleAm J Clin Dermatol · July 2023
With more disease- and symptom-specific measures available and research pointing to increased usefulness, patient-reported outcome measures (PROMs) can be routinely used in clinical care. PROMs increase efficiency in healthcare, improve the clinician-patie ...
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Journal ArticleJ Am Acad Dermatol · May 2023
BACKGROUND: Teledermatology is comparable to face-to-face visits in providing accurate diagnoses and effective treatments. However, there are limited data regarding patient satisfaction with teledermatology models that more directly convey provider recomme ...
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Journal ArticleJ Am Acad Dermatol · May 2023
The United States population is aging and increasing in comorbidities, and patient care is accordingly growing increasingly complex. Complexity impacts patterns of resource consumption, adverse event and medical error rates, health-related quality of life, ...
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Journal ArticleLGBT Health · May 2023
Purpose: Skin cancer is prevalent in sexual minority men but little is known about risk factors and screening specifically among couples in same-sex relationships (SSR). We aimed to compare sunburns, sun-protective behaviors, indoor tanning, and total body ...
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Journal ArticleJID Innov · May 2023
We sought to project the 1-year cost utility of nonpregnancy laboratory monitoring cessation among patients initiating isotretinoin. We conducted a model-based cost utility analysis comparing (i) current practice (CP) and (ii) cessation of nonpregnancy lab ...
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Journal ArticleJ Am Acad Dermatol · May 2023
BACKGROUND: Patients with single primary melanomas have an increased risk of developing subsequent melanomas. Secondary tumors diagnosed within and after 3Â months are termed "synchronous" and "asynchronous," respectively. OBJECTIVE: To compare tumor distri ...
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Journal ArticleRes Sq · February 28, 2023
BACKGROUND: Teledermatology (TD) is an evidence-based practice that may increase access to dermatologic care. We sought to evaluate implementation of TD at four Duke primary care practices. METHODS: We implemented a hybrid TD program where trained primary ...
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Journal ArticleBr J Dermatol · January 23, 2023
BACKGROUND: Pain is rated by patients with hidradenitis suppurativa (HS) as the disease's most impactful symptom. HS therapies are often insufficient to control inflammatory disease activity and pain. A better understanding of patient experiences with pain ...
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Journal ArticlePharmacoepidemiol Drug Saf · September 2022
PURPOSE: Actinic keratoses (AK) diagnosis, billing, and pharmacy codes have not been validated among people living with human immunodeficiency virus (HIV), preventing use in epidemiologic and clinical research. We aimed to calculate the positive predictive ...
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Journal ArticleDermatol Pract Concept · July 2022
INTRODUCTION: Improving remote triage is crucial given expansions in tele-dermatology and with limited in-person care during COVID-19. In addition to clinical pictures, dermoscopic images may provide utility for triage. OBJECTIVES: To determine if dermosco ...
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Journal ArticleJAMA Dermatol · March 1, 2022
IMPORTANCE: Asian American individuals are the fastest growing racial group in the US but remain underrepresented in health disparities research, including research on skin cancer risk factors and screening. Improved understanding of preventable skin cance ...
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Journal ArticleIproceedings · December 20, 2021
BackgroundTeledermatology can increase patient access; however, its optimal implementation remains unknown.Obj ...
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Journal Article · December 3, 2021
BACKGROUNDTeledermatology can increase patient access; however, its optimal implementation remains unknown.
...
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Journal ArticlePediatr Dermatol · September 2021
BACKGROUND/OBJECTIVES: Validated pruritus-specific quality of life and self-reported severity instruments exist primarily for adults. Clinical trials to develop therapeutics for children with chronic pruritus are hampered by the paucity of appropriate outc ...
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Journal ArticleBr J Dermatol · September 2021
BACKGROUND: The ItchyQoL is an itch-specific patient-reported outcome measure used to assess quality of life in patients with chronic pruritus (CP). OBJECTIVES: We aimed to assess and extend the psychometric properties of the ItchyQoL using classical test ...
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Journal ArticlePediatr Dermatol · May 2021
BACKGROUND/OBJECTIVES: Measures of pruritus severity and quality of life (QoL) are necessary for the development of therapeutics for children with chronic pruritus. In children, questionnaires need to be developed for specific age groups given the differen ...
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Journal ArticleUltrasound J · April 20, 2021
BACKGROUND: Ultrasound was first introduced in clinical dermatology in 1979. Since that time, ultrasound technology has continued to develop along with its popularity and utility. Today, high-frequency ultrasound (HFUS), or ultrasound using a frequency of ...
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Journal ArticleJAMA Dermatol · April 1, 2021
This cross-sectional survey characterizes the knowledge, attitudes, and practices of international experts in the management of pain in patients with hidradenitis suppurativa. ...
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Journal ArticleJ Invest Dermatol · October 2020
Skin conditions can significantly impact QOL. Dermatology QOL instruments may measure general skin-specific, disease-specific, or condition-specific QOL. Key components in the development of QOL instruments include (i) instrument and conceptual framework d ...
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Journal ArticleJAMA Dermatol · October 1, 2020
IMPORTANCE: Acne is a common dermatologic condition and significantly affects psychosocial health and quality of life. An international task force recommended routine use of quality-of-life measures for clinic visits associated with acne management, but th ...
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Journal ArticleJ Am Acad Dermatol · August 2020
BACKGROUND: Long-term safety of topical calcineurin inhibitors is not well understood. APPLES (AÂ Prospective Pediatric Longitudinal Evaluation to Assess the Long-Term Safety of Tacrolimus Ointment for the Treatment of Atopic Dermatitis; NCT00475605) examin ...
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Journal ArticleCancer · April 15, 2020
BACKGROUND: Cutaneous T-cell lymphoma (CTCL) is a rare form of non-Hodgkin lymphoma arising in the skin. Geographic clustering of CTCL has recently been reported, but its association with environmental factors is unknown. Benzene and trichloroethylene (TCE ...
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Chapter · March 20, 2020
Itch and Pain: Similarities, Interactions and Differences is the only available, up-to-date guide to current information in this important area, ideal for basic scientists as well as clinicians in dermatology, pain, neurology, medicine, ... ...
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Journal ArticleJ Cutan Med Surg · 2020
BACKGROUND: Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease that severely impairs patients' quality of life (QoL). Instruments such as the 10-item Dermatology Life Quality Index and 16-item Skindex-16 have been used to assess QoL in HS ...
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Journal ArticleJ Am Acad Dermatol · October 2019
BACKGROUND: Timely treatment for melanoma may affect survival, and characterizing the predictors of delay may inform intervention strategies. OBJECTIVE: To determine characteristics associated with the interval between diagnosis and surgery in melanoma. ME ...
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Journal ArticleJAMA Dermatol · October 1, 2019
IMPORTANCE: To date, no concerted effort has been made to date to evaluate the literature on number-needed-to-biopsy (NNB) metrics, particularly to account for the differences in clinician type and melanoma prevalence in certain geographic locations. OBJEC ...
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Journal ArticleJ Am Acad Dermatol · March 2019
Lesbian, gay, bisexual, and transgender (LGBT) persons face important health issues relevant to dermatologists. Men who have sex with men (MSM) are at higher risk of certain infectious diseases, including HIV, syphilis and other sexually transmitted diseas ...
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Journal ArticleJ Am Acad Dermatol · March 2019
More than 10 million lesbian, gay, bisexual, and transgender (LGBT) persons live in the United States. Improving their health is a public health priority. LGBT persons have specific health concerns and face health care disparities. Awareness of those issue ...
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Journal ArticleJ Am Acad Dermatol · March 2019
In our evolving health care system, dermatologists are increasingly being asked to prove the value of care they provide to patients with severe skin diseases. Current quality measures for inflammatory dermatoses have limited validity and feasibility. Throu ...
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Journal ArticleJ Eur Acad Dermatol Venereol · February 2019
BACKGROUND: Chronic pruritus (CP) is a frequently occurring symptom in inflammatory dermatoses, causing a high burden and limitations to health-related quality of life (HRQoL). OBJECTIVE: The ItchyQoL was developed to assess the impairment to HRQoL in pati ...
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Journal ArticleCancer · January 1, 2019
Recent progress in the treatment of advanced melanoma has led to unprecedented improvements in overall survival and, as these new melanoma treatments have been developed and deployed in the clinic, much has been learned about the natural history of the dis ...
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Journal ArticleJ Assoc Nurses AIDS Care · 2019
Skin cancers-including basal cell carcinoma, squamous cell carcinoma, and melanoma-impose high incidence and morbidity in older persons. As life expectancy continues to increase in persons living with HIV (PLWH), this population may face an increased risk ...
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Journal ArticleItch · December 2018
Introduction:Chronic pruritus (CP) is a common symptom, but can be a diagnostic and therapeutic challenge. Our objective was to determine how personality traits, and more specifically per ...
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Journal ArticleJAMA Dermatol · December 1, 2018
IMPORTANCE: Little evidence exists to guide the management of moderately dysplastic nevi excisionally biopsied without residual clinical pigmentation but with positive histologic margins (hereafter referred to as moderately dysplastic nevi with positive hi ...
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Journal ArticleInt J Dermatol · November 2018
BACKGROUND: Teledermatology may improve dermatologic care access in underserved areas and expand the clinical experience of dermatologists-in-training. The potential for teledermatology to supplement global health curricula in dermatology residency educati ...
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Journal ArticleJAMA Dermatol · November 1, 2018
IMPORTANCE: Actinic keratosis is prevalent and has the potential to progress to keratinocyte carcinoma. Changes in the use and costs of actinic keratosis treatment are not well understood in the aging population. OBJECTIVE: To evaluate trends in the use an ...
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Journal ArticlePediatr Dermatol · September 2018
BACKGROUND/OBJECTIVES: Despite rising skin cancer rates in children, multiple studies reveal inadequate youth sun-protective behavior (eg, sunscreen use). Using Healthy Passages data for fifth-graders, we set out to determine sunscreen adherence in these c ...
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Journal ArticleJ Cutan Pathol · August 2018
BACKGROUND: Diagnostic accuracy with whole slide imaging (WSI) for complex inpatient and outpatient dermatopathology cases with immunohistochemistry (IHC) is unknown. METHODS: WSI (Leica Aperio AT2 Digital Pathology scanner, N = 151 cases) was performed fo ...
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Journal ArticleExp Dermatol · June 2018
Infantile haemangiomas (IHs) with functional or cosmetic concerns necessitate systemic treatment for which propranolol is the preferred treatment. However, the mechanism of action is unknown. Mouse models suggest the angiopoietin-2 (Ang2)/Tie-2 system is i ...
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Journal ArticlePediatr Dermatol · May 2018
Atopic dermatitis is the most common chronic skin disease, and it primarily affects children. Although atopic dermatitis (AD) has the highest effect on burden of skin disease, no high-level studies have defined optimal therapy for severe disease. Corticost ...
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ConferenceJAMA Dermatol · February 1, 2018
IMPORTANCE: Keratinocyte carcinoma (ie, cutaneous basal and squamous cell carcinoma) is the most common cancer in the United States. OBJECTIVE: To determine whether topical fluorouracil could prevent surgically treated keratinocyte carcinoma. DESIGN, SETTI ...
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Journal ArticleGeriatr Nurs · 2018
A skin care regimen which significantly improved atopic dermatitis and pruritus was evaluated for its efficacy and acceptability in senior subjects diagnosed with xerosis who also suffer from pruritus. This was an open-label, single-center study, designed ...
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Journal ArticleCurrent Dermatology Reports · December 1, 2017
Purpose of Review: Complementary and alternative medicine (CAM) is widely used by patients who suffer from chronic pruritus, but there is little data on the efficacy or antipruritic mechanism of these interventions. This review assesses the current underst ...
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Journal ArticleDermatol Online J · September 15, 2017
BACKGROUND: Video-based patient education about long-term systemic corticosteroid treatment has not been assessed. OBJECTIVE: To compare video-based versus verbal education in patient knowledge gained and satisfaction. METHODS: English-speaking adults (≥18 ...
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Journal ArticleDermatol Online J · September 15, 2017
Trends in the training, supply, availability, career decisions, and retirement of US dermatology physicians are not well delineated. The current study evaluates whether growth in the dermatology workforce will keep pace with population expansion in the Uni ...
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Journal ArticleClin Exp Dermatol · July 2017
BACKGROUND: Topical 5-fluorouracil (5-FU) is commonly used for high-risk patients with keratinocyte carcinoma (KC). Skindex and Skin Cancer Index (SCI) are validated instruments to measure quality of life (QoL) of patients with KC and those who have had su ...
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Journal ArticleJ Am Acad Dermatol · July 2017
BACKGROUND: Chronic pruritus has a lifetime prevalence of up to 26% in the worldwide population. Research has shown that the incidence and quality of life (QoL) impact of chronic pruritus varies by race. OBJECTIVE: We sought to explore the effects of race ...
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Journal ArticleInt J Womens Dermatol · March 2017
Women are entering medicine at increasing rates, particularly in dermatology. In this study, we compared women's influence and status in academic dermatology with that of men by examining authorship roles in peer-reviewed dermatology literature. We examine ...
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Journal ArticleDermatol Online J · January 15, 2017
IMPORTANCE: There have been no attempts to determinethe understanding of the Affordable Care Act (ACA)among dermatologists. OBJECTIVE: Assess knowledgeof the ACA among academic dermatologists. DESIGN: A 21-item survey was administered to membersof the Asso ...
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Journal ArticleJ Invest Dermatol · January 2017
Because of the significant emotional and psychosocial impact of chronic pruritus, it is important to accurately assess and measure itch severity. This study aims to validate and apply clinically meaningful bands to the ItchyQuant, an illustrated self-repor ...
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Journal ArticleDermatology Online Journal · January 1, 2017
Trends in the training, supply, availability, career decisions, and retirement of US dermatology physicians are not well delineated. The current study evaluates whether growth in the dermatology workforce will keep pace with population expansion in the Uni ...
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Journal ArticleDermatol Online J · June 15, 2016
BACKGROUND: Botulinum toxin type A (BTX-A) injections are an effective treatment for controlling hyperhidrosis at sites of amputation. Hyperesthesia associated with amputated limbs is a major barrier to performing this procedure under local anesthesia. OBJ ...
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Journal ArticleInt J Womens Dermatol · March 2016
Women are entering medicine at increasing rates, particularly in dermatology. In this study, we compared women's influence and status in academic dermatology with that of men by examining authorship roles in peer-reviewed dermatology literature. We examine ...
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Journal ArticleJ Am Acad Dermatol · March 2016
INTRODUCTION: Several treatment options exist for uncomplicated basal cell carcinoma. Standardized and effective informed consent is difficult in busy dermatology clinics. OBJECTIVE: We investigated whether an educational video depicting 3 treatment option ...
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Chapter · January 20, 2016
Pragmatic and reader-friendly, Vitamin D: A Clinical Casebook will be an excellent resource for clinical endocrinologists, nutritionists, and family and emergency medicine physicians alike. ...
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Chapter · 2016
Detection and removal of melanoma, before it has metastasized, dramatically improves prognosis and survival. The purpose of this chapter is to (1) summarize current methods of melanoma detection and (2) review state-of-the-art detection methods and technol ...
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ConferenceJAMA Dermatol · September 2015
IMPORTANCE: Topical fluorouracil was demonstrated to be effective in reducing the number of actinic keratoses (AKs) for up to 6 months, but no randomized trials studied its long-term efficacy. OBJECTIVE: To evaluate the long-term efficacy of a single cours ...
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Journal ArticleJAMA Dermatol · March 2015
IMPORTANCE: Patients with venous leg ulcers (VLUs) have calf muscle pump dysfunction, which is associated with reduced ankle range of motion (ROM). Physical therapy or exercise that targets ankle joint mobility may lead to improvement in calf muscle pump f ...
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Journal ArticleJAMA Dermatol · February 2015
IMPORTANCE: The management of clinically atypical nevi/dysplastic nevi (CAN/DN) is controversial, with few data to guide the process. Management recommendations for DN with positive histologic margins were developed by the Delphi method to achieve consensu ...
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Journal ArticleJAMA Dermatol · February 2015
IMPORTANCE: Cancer worry about developing melanoma in at-risk patients may affect one's quality of life and adherence to screening. Little is known about melanoma-related worry in patients with atypical mole syndrome (AMS). OBJECTIVES: To quantify levels a ...
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Journal ArticleJ Skin Cancer · 2015
The goal of our study was to determine current melanoma reporting methods available to dermatologists and dermatopathologists and quantify changes in reporting methods from 2012 to 2014. A cross-sectional study design was utilized consisting of website per ...
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Journal ArticleHandb Exp Pharmacol · 2015
The burden of chronic pruritus is increasingly recognized as significant worldwide. As wet-laboratory researchers investigate the pathophysiology of chronic pruritus, epidemiologists and health services researchers are quantifying the impact of pruritus by ...
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Journal ArticleJAMA Dermatol · November 2014
IMPORTANCE: There is an increasing demand for a limited number of pigmented lesion clinic (PLC) visits at dermatology centers. OBJECTIVE: To determine the proportion of visits to PLCs that are more frequent ("additional screening") than the recommended ("s ...
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Chapter · August 11, 2014
This chapter outlines the four fundamental types of pharmacoeconomic studies, gives dermatological examples, and discusses the necessary items for such studies. Cost analyses are useful as sources of rigorous cost accounting and as the basis for other phar ...
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Journal ArticlePhotodermatol Photoimmunol Photomed · August 2014
PURPOSE: Little is known about handheld umbrella (HU) use for sun protection in the United States. We sought to determine whether women consider the HU a socially acceptable form of sun protection and whether viewing pictures of famous women carrying umbre ...
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Journal ArticleJ Dtsch Dermatol Ges · July 2014
OBJECTIVES: To determine the biopsy sensitivity to melanoma of dermatologists in Germany and the impact of MelaFind® on their decisions to biopsy melanomas. DESIGN: Randomized two-armed online reader study presenting case information, clinical/dermatoscopi ...
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Chapter · June 5, 2014
Be sure your skin-care treatments have strong evidential support Evidence-based Dermatology, Third Edition takes a unique approach to clinical dermatology by emphasising use of only the highest quality available evidence when treating ... ...
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Chapter · June 5, 2014
Be sure your skin-care treatments have strong evidential support Evidence-based Dermatology, Third Edition takes a unique approach to clinical dermatology by emphasising use of only the highest quality available evidence when treating ... ...
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Journal ArticleJAMA Dermatol · June 2014
IMPORTANCE: Chronic pruritus is a common problem with a deleterious effect on quality of life. The factors mediating the relationship between chronic pruritus and quality of life are poorly understood. OBJECTIVE: To determine the factors that mediate the i ...
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Journal ArticlePain Med · May 2014
OBJECTIVE: Utilities are values of health-related quality of life (HRQoL) based on patient preference for a health status. The purpose of this study was to compare indirect measures to a directly elicited utility. DESIGN: Cross-sectional study. SETTING AND ...
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Journal ArticleJ Am Acad Dermatol · April 2014
BACKGROUND: Prevalence of chronic pruritus in HIV-positive patients is an underevaluated topic in the United States. The characteristics, severity, and quality of life (QOL) in patients with HIV and chronic pruritus have not been well documented using vali ...
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Journal ArticleJ Cutan Pathol · February 2014
BACKGROUND: As histopathologic assessment is subject to sampling error, some institutions 'preorder' deeper sections on some or all cases (hereafter referred to as prospective deeper sections), while others order additional sections only when needed (herea ...
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Journal ArticleJ Cutan Med Surg · 2014
BACKGROUND: Topical 5% 5-fluorouracil (5-FU) is known to cause toxicity, such as erythema, pain, and crusting/erosions. OBJECTIVES: We sought to develop a scale to measure this toxicity and test the scale for reliability. METHODS: A scale was developed inv ...
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Journal ArticleBr J Dermatol · December 2013
BACKGROUND: Enumerating actinic keratoses (AKs) is highly variable but important to standardize as new therapies are emerging. OBJECTIVES: To assess the reliability of four different methods used to quantify AKs and to investigate whether a consensus meeti ...
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Journal ArticleActa Derm Venereol · September 4, 2013
Pruritus is a major symptom of numerous skin and systemic diseases and causes a substantial burden on patients' quality of life (QoL). We report here the validation of the German version (GerItchyQoL) of the first pruritus-specific QoL instrument ItchyQoL. ...
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Journal ArticleLeuk Lymphoma · February 2013
Patients with cutaneous T-cell lymphoma (CTCL) frequently experience severe pruritus that can significantly impact their quality of life. Romidepsin is approved by the US Food and Drug Administration (FDA) for the treatment of patients with CTCL who have r ...
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Journal ArticleCurr Oncol Rep · October 2012
Controversy has emerged over the past decades regarding the value and impact of melanoma screening to detect early stage disease for improved prognosis. Those questioning the benefits of prevention efforts base their arguments on the absence of prospective ...
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Journal ArticleDermatol Surg · August 2012
OBJECTIVE: To determine whether there is an association between duration of voriconazole therapy and number of nonmelanoma skin cancers (NMSC) after lung transplantation. DESIGN: A telephone-based survey and chart review were performed for all living patie ...
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Journal ArticleVasc Cell · July 5, 2012
Tuberous sclerosis (TS) is a common autosomal-dominant disorder characterized by tumors of the skin, lung, brain, and kidneys. Monotherapy with rapamycin however resulted in partial regression of tumors, implying the involvement of additional pathways. We ...
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Journal ArticleJ Invest Dermatol · July 2012
Willingness to pay (WTP) is a monetary, preference-based, burden-of-disease measure with a potential role in dermatology, where many conditions are temporary and/or mild, and many treatments are inexpensive and one might be able to imagine paying out of po ...
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Journal ArticleArch Dermatol · April 2012
OBJECTIVES: To establish the effect of sunless tanning products on tanning behaviors and to determine characteristics of sunless tanning product users. DESIGN: A cross-sectional survey study conducted between May 30, 2007, and December 4, 2007. SETTING: Th ...
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Journal ArticleDermatol Clin · April 2012
Within the last few decades, outcomes research, and in particular quality of life (QoL) outcomes research, has become integrated into clinical and research practices. QoL outcomes are important to dermatology, because many diseases carry significant psycho ...
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Journal ArticleDermatol Clin · April 2012
Health-related quality of life (QoL) is a patient-reported outcome that describes the impact of the disease in question to all aspects of persons' life, including psychosocial, emotional, physical, and functional impact. As such, health-related QoL is part ...
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Journal ArticleDermatol Clin · April 2012
Clinical meaning can be assigned to scores of health status measures by using a variety of approaches. The anchor-based approach involves determining the difference on a quality of life (QOL) scale that corresponds to a self-reported small but important ch ...
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Journal ArticleDermatol Clin · April 2012
In this overview of preference-based measures, utilities and willingness to pay (WTP) are discussed as measures relevant to dermatology for capturing the burden of skin diseases. An overview is provided of the concepts of utilities and WTP and their import ...
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Journal ArticleDermatol Clin · April 2012
Improvement of health-related quality of life (HRQoL) is a major goal of dermatology. Identifying how the skin condition affects lives, quantifying this burden, and using this information to improve patients' lives on an individual basis are important targ ...
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Journal ArticleDermatol Clin · April 2012
The concept of quality of life (QOL) is becoming increasingly important in medicine, particularly in dermatology where many cutaneous diseases have the potential to affect the quality rather than the length of life. There is increasing interest in devising ...
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Journal ArticleCutis · March 2012
Sweet syndrome (SS) is a distinctive but poorly understood clinical syndrome, which likely represents an immunologic reaction pattern to a wide range of underlying or preceding conditions, including viral illnesses, inflammatory bowel disease, and malignan ...
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Journal ArticleBiochem Biophys Res Commun · December 16, 2011
Circadian rhythm is a fundamental biological system involved in the regulation of various physiological functions. However, little is known about a nature or function of circadian clock in human primary cells. In the present study, we have applied in vitro ...
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Journal ArticleBlood · November 18, 2011
AbstractAbstract 3158Background:In addition to being itchy and painful, cutaneous T cell lymphoma (CT ...
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Journal ArticleJ Am Acad Dermatol · November 2011
BACKGROUND: Cutaneous melanoma is the most deadly form of skin cancer with more than 8000 deaths per year in the United States. The health burden and economic costs associated with melanoma mortality by race/ethnicity have not been appropriately addressed. ...
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Journal ArticleJ Am Acad Dermatol · November 2011
BACKGROUND: Every state requires diagnosing physicians to report new cases of melanoma to its central cancer registry. Previous regional studies and anecdotal experience suggest that few dermatologists are cognizant of this obligation. This oversight could ...
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Journal ArticleArch Dermatol · October 2011
OBJECTIVE: To compare the impact of chronic pruritus and chronic pain on quality of life (QoL) using directly elicited health utility scores. DESIGN: Cross-sectional study. SETTING: Convenience sample of patients attending the Emory Dermatology Clinic, Emo ...
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Journal ArticleAm Surg · August 2011
Disagreement persists regarding the role that various biopsy methods should play in the diagnosis of primary cutaneous melanoma. We analyzed the indications for sentinel lymph node (SLN) biopsy and the rates of SLN involvement among biopsy techniques and d ...
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Journal ArticleCancer Causes Control · July 2011
BACKGROUND: Sun protection messages in the United States emphasize sunscreen use, although its efficacy in skin cancer prevention remains controversial. METHODS: We used data from NHANES 2003-2006, restricted to adult whites (n = 3,052) to evaluate how Ame ...
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Journal ArticleDermatol Surg · March 2011
BACKGROUND: Dermatologists perform more cutaneous surgical procedures than any other medical specialists, including plastic surgeons, especially for treating skin cancers, but anecdotal evidence suggests that the public may not identify dermatologists as s ...
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Journal ArticlePediatr Dermatol · 2011
We explored resource utilization (ResUtil) and quality of life (QOL) associated with congenital ichthyoses (CI). Subjects completed an online survey related to clinical severity, demographics, ResUtil, and QOL as measured according to the Dermatology Life ...
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Journal ArticleDermatol Surg · November 2010
BACKGROUND: Despite strong evidence that sun exposure causes skin cancer, a significant proportion of the population continues to purposefully tan. Many individuals deliberately tan because they believe a tanned complexion makes them appear more attractive ...
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Journal ArticleMelanoma Res · October 2010
The primary objective of our study was to update the prevalence of total body photography (TBP) utilization and the rationale for its implementation as an adjunctive screening measure by academic dermatologists across the USA, and investigate the emergence ...
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Journal ArticleSemin Cutan Med Surg · September 2010
Photoprotection against ultraviolet light is an important part of our armamentarium against actinically derived skin cancers. However, there has been concern that adherence to photoprotection may lead to low vitamin D status, leading to negative effects on ...
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Journal ArticleArchives of Dermatology · March 1, 2010
Objective: To assess health care resources consumed by melanoma in the population 65 years or older, a group with comparatively poor outcomes. Design: Database analysis. Setting: The Surveillance, Epidemiology, and End Results (SEER)-Medicare-linked popula ...
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Journal ArticlePediatr Dermatol · 2010
The aim of this study is to estimate annual, per patient, health care costs for congenital ichthyoses (CI). We conducted a cost analysis through an online survey posted on the Foundation for Ichthyosis and Related Skin Types Website. We assessed cutaneous ...
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Journal ArticlePediatr Dermatol · 2010
The ectodermal dysplasias are a complex, heritable group of syndromes that affect derivatives of ectoderm. The dermatologist plays an important role in ectodermal dysplasias as the visible defects of skin, hair, and nails are often recognized first. Our ob ...
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Journal ArticlePediatr Dermatol · 2010
A reliable method for assessing ichthyosis severity has not been uniformly agreed upon. The objective of our study was to develop and validate a tool to measure the clinical severity of the congenital ichthyoses, the Congenital Ichthyoses Severity Index. A ...
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Journal ArticleJ Invest Dermatol · December 2009
In this issue, Gordon et al. report a novel study evaluating the cost-effectiveness of promoting sunscreen use to prevent actinic keratoses and nonmelanoma skin cancer. This cost-effectiveness analysis (CEA) provides important data for health policy makers ...
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Journal ArticleDermatol Surg · November 2009
OBJECTIVE: To evaluate and compare Mohs micrographic surgery and traditional excision in terms of cost and outcomes. DESIGN: We developed a computer-simulation, probabilistic, decision model to perform a cost-effectiveness analysis, with each patient servi ...
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Journal ArticleHum Pathol · May 2009
Virtual microscopy is being used in medical schools to teach histology and pathology. It is also being used in resident education, in-training examinations (dermatology), and certification examinations (pathology). There are, however, few studies comparing ...
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Chapter · January 22, 2009
This edition is much expanded with a greater focus on patients. New chapters include: What makes a good case series? ...
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Chapter · January 22, 2009
This edition is much expanded with a greater focus on patients. New chapters include: What makes a good case series? ...
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Journal ArticleJ Eur Acad Dermatol Venereol · January 2009
BACKGROUND: Disseminated superficial actinic porokeratosis (DSAP) is a chronic cutaneous disorder of keratinization for which there is no known cure. Current therapies are often ineffective, painful, or unappealing. OBJECTIVE: To investigate the efficacy a ...
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Journal ArticleJ Am Acad Dermatol · August 2008
OBJECTIVE: We sought to develop a validated, reliable pruritus-specific quality-of-life (QOL) instrument, ItchyQoL. METHODS: From 21 in-depth interviews with patients with pruritus, we developed 22 pruritus-specific items, and hypothesized 3 major construc ...
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Journal ArticleAnn Allergy Asthma Immunol · March 2008
BACKGROUND: Altered basophil degranulation phenotypes are found in patients with chronic idiopathic urticaria (CIU). OBJECTIVE: To evaluate CIU disease severity in relation to basophil histamine release (HR) characteristics. METHODS: Patients with CIU were ...
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Journal ArticleArch Dermatol · January 2008
OBJECTIVE: To estimate annual direct and indirect health care costs in patients with chronic idiopathic urticaria (CIU) managed with conventional therapies. DESIGN: A cost analysis consisting of a survey-guided and retrospective medical record review of di ...
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Journal ArticleMycoses · January 2008
A valid and reliable measure that captures onychodystrophy disease severity is important for both clinical and research applications. Three hundred and twenty-two patients at two Veterans Affairs Medical Centers with clinical evidence of onychodystrophy su ...
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Journal ArticleJ Am Acad Dermatol · January 2008
BACKGROUND: Onychomycosis (fungal infection of the toenails or fingernails) is common, affecting up to 8% of the general population. Telephone and mailed surveys conducted to study this disease are usually completed via patient self-report. The validity of ...
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Journal ArticleInt J Dermatol · December 2007
BACKGROUND: The disease burden onychomycosis is not trivial. The aim is to develop a quality of life instrument to measure the onychomycosis burden. METHODS: 402 patients with mycologically-confirmed onychomycosis completed a baseline questionnaire of 39 q ...
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Journal ArticleJ Am Acad Dermatol · September 2007
BACKGROUND: Total body cutaneous photography is increasingly being used by dermatologists to monitor patients at risk for the development of melanoma, but limited evidence exists regarding the impact of such photography on melanoma and melanoma-related out ...
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Journal ArticleJ Am Acad Dermatol · August 2007
BACKGROUND: No rosacea-specific quality-of-life (QOL) instrument exists. OBJECTIVE: We sought to develop a validated, reliable rosacea-specific instrument. METHODS: From 6 in-depth interviews, we composed 21 rosacea-specific items. These items and Skindex- ...
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Journal ArticleBr J Dermatol · May 2007
BACKGROUND: Willingness-to-pay (WTP) is a health economics measure that has recently been used for skin diseases to evaluate patients' quality of life. However, the reliability of this measure has not been investigated in the dermatology literature and is ...
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Journal ArticleArch Dermatol · April 2007
OBJECTIVE: To determine whether a difference in melanoma outcomes exists in the United States between tumors detected by dermatologists vs those detected by nondermatologists. DESIGN: Retrospective analysis of linked data from the Medicare enrollment and c ...
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Journal ArticleJ Am Acad Dermatol · February 2007
BACKGROUND: There are no studies evaluating the comprehension of terms used by dermatologists to describe acne lesions. OBJECTIVE: The goal is to evaluate the comprehension of terms and pictures representing various acne lesions. METHODS: Patients were ask ...
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Journal ArticleArch Dermatol · January 2007
OBJECTIVE: To compare the effect of differing health care delivery models, specifically, gatekeeper (GK) vs direct access (DA) routes, on melanoma outcome as measured by tumor thickness and cancer stage at diagnosis. DESIGN: Retrospective medical record re ...
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Journal ArticleDermatol Surg · January 2007
BACKGROUND: Patients with thick (Breslow>4 mm) primary melanoma and/or regional nodal metastasis have a high risk of tumor recurrence. High-dose adjuvant interferon (IFN) alfa-2b offers
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Journal ArticleDermatol Ther · 2007
Patient quality of life (QOL) is an important aspect of health care. It is crucial that we continue to develop instruments to assist in detecting burden of disease, interpreting outcomes of clinical trials, determining cost effectiveness of therapies, and ...
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Journal ArticleTelemed J E Health · December 2006
The objective of this study was to evaluate willingness-to-pay stated preferences for telemedicine versus in-person clinic visits in patients with a history of psoriasis or melanoma. Face-to-face interviews were conducted with 92 (n = 92) adult participant ...
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Journal ArticleDermatol Surg · December 2006
BACKGROUND: Solid organ transplant recipients on high doses of immunosuppression are at increased risk for the development of nonmelanoma skin cancer (NMSC). OBJECTIVE: The objective was to assess the possible factors impacting quality of life (QOL) in sol ...
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Journal ArticleJ Gen Intern Med · July 2006
BACKGROUND: Primary care physicians (PCPs) are often expected to screen for melanomas and refer patients with suspicious pigmented lesions to dermatologists. OBJECTIVE: To assess whether there is a difference between dermatologists and PCPs in accurately d ...
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Journal ArticleAm Heart J · June 2006
Percutaneous coronary intervention (PCI) remains a major therapeutic option for the treatment of chronic coronary artery disease. In the COURAGE trial, 2287 patients with chronic coronary disease were randomized between PCI with medical management and medi ...
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Journal ArticleJ Invest Dermatol · March 2006
Dermatologists treat actinic keratoses to prevent non-melanoma skin cancer. Evaluation of actinic keratosis therapy depends on reliable measures of the lesions. The commonly used method of directly counting all visible lesions has been shown to be unreliab ...
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Journal ArticleArch Dermatol · February 2005
BACKGROUND: Sarcoidosis, which occurs most commonly in African American women, is a granulomatous multisystem disorder affecting the skin, lungs, and central nervous system. In a previous immunohistochemistry study of keloids, a scar granuloma stained high ...
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Journal ArticleArch Dermatol · June 2004
OBJECTIVE: To compare the cost and margin adequacy of Mohs micrographic surgery (Mohs) and traditional surgical excision (TSE) for the treatment of facial and auricular nonmelanoma skin cancer (NMSC). DESIGN: Prospective cost analysis with each patient ser ...
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Journal ArticleJ Investig Dermatol Symp Proc · March 2004
Utilities are measures of quality of life that reflect the strength of individuals' preferences or values for a particular health outcome. As such, utilities represent a measure of disease burden. The aim of this article is to introduce the concept of util ...
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Journal ArticleJ Am Acad Dermatol · June 2003
BACKGROUND: The role of angiogenesis in infectious processes is poorly studied. Some viruses have been linked to angiogenesis, but the role of bacteria and protozoa in inducing angiogenesis in chronic infections is poorly understood. OBJECTIVES: We examine ...
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Journal ArticleJ Am Acad Dermatol · October 2002
BACKGROUND: Squamous cell carcinoma (SCC) is the most common skin cancer in African Americans, but its incidence is low. Although incompletely described in the literature, an increased incidence of SCC in sun-protected areas in black patients has been repo ...
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Journal ArticleJ Am Acad Dermatol · August 2002
Fewer and fewer residents appear to be choosing careers in academic dermatology and research. Recognizing the impact that this trend would have on the future of our specialty, the Society for Investigative Dermatology invited a group of dermatology residen ...
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Journal ArticleArch Dermatol · June 2002
OBJECTIVE: To develop a scalp dermatitis-specific quality-of-life instrument. METHODS: Based on the results of directed focus sessions with 8 patients with scalp psoriasis or seborrheic dermatitis, we conceptualized 3 major constructs that explain the way ...
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Journal ArticleArch Dermatol · December 2001
OBJECTIVE: To compare the accuracy of dermatologists and primary care physicians (PCPs) in identifying pigmented lesions suggestive of melanoma and making the appropriate management decision to perform a biopsy or to refer the patient to a specialist. DATA ...
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Journal ArticleJournal of Cutaneous Medicine and Surgery · May 2001
Background: In the current age of limited health care resources, cost-effectiveness analyses are important since they provide information that can be used by decisionmakers for prioritizing and setting health care ...
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Journal ArticleJ Cutan Med Surg · 2001
BACKGROUND: In the current age of limited health care resources, cost-effectiveness analyses are important since they provide information that can be used by decision-makers for prioritizing and setting health care policies. OBJECTIVE: This article gives a ...
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Journal ArticleArch Dermatol · December 1998
OBJECTIVE: To analyze the net benefit and cost-effectiveness of methotrexate use and Goeckerman therapy for psoriasis. DESIGN: Net benefit and cost-effectiveness depend on the costs, efficacy, and utilities of therapy. Utilities are quantitative measures o ...
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Journal ArticleJ Am Acad Dermatol · August 1998
Eccrine syringofibroadenoma (ESFA) is a rare benign adnexal tumor, generally with sporadic occurrence and not linked to other diseases. Only one familial occurrence of ESFA has been reported. We describe the familial occurrence of multiple ESFAs in a fathe ...
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Journal ArticleMayo Clin Proc · June 1997
To examine inconsistencies between the growth in incidence of melanoma and more modest changes in melanoma-related mortality, we reviewed the medical literature on the incidence of melanoma diagnosis and associated mortality and on the changes in diagnosis ...
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Journal ArticleArch Dermatol · August 1996
Melanoma has a very bad reputation, and rightfully so. Until relatively recently, the prognosis for melanoma was dismal and, very reasonably, early detection has been proposed as a viable approach to preventing melanoma deaths. On the surface, this simple ...
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Journal ArticleMedicine (Baltimore) · May 1995
To explore further the varied clinical expression of anti-Ro(SS-A) antibody positive patients and to determine the outcomes of these patients, we followed 100 anti-Ro(SS-A) antibody positive patients, originally seen at the Johns Hopkins Medical Institutio ...
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