Scholarly Works - Book sections
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January 1, 2025
Cancer is among the leading causes of death in most countries, including the United States. Genetics and exposure to carcinogens in the environment each play major roles in causing cancer. In this chapter, we discuss the interplay between the biology of ca ...
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July 1, 2016
DNA methylation is a stable yet reversible epigenetic modification that regulates gene expression. New technologies have provided deep insights into the distribution and function of DNA methylation in humans, including the Human Roadmap Epigenome Project t ...
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June 21, 2016
The intent of this book is to provide a stand-alone comprehensive volume that will cover all human systems relevant to epigenetic maladies and all major aspects of medical epigenetics. ...
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January 1, 2016
Cadmium, arsenic, mercury and lead are ubiquitous environmental contaminants that tend to co-occur. Unlike organic compounds that are chemically, biologically, or photo-degraded, these metals persist in the environment for indefinite periods. Although prot ...
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July 7, 2015
Epigenetics can be defined as the heritable perpetuation of gene activity without modification of the DNA sequence. Epigenetic mechanisms include methylation of cytosine residues within the DNA sequence and the posttranslational modification of histone pro ...
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June 11, 2015
Systems Biology in Toxicology and Environmental Health uses a systems biological perspective to detail the most recent findings that link environmental exposures to human disease, providing an overview of molecular pathways that are ... ...
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May 31, 2013
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September 17, 2010
This chapter discusses the mouse models of epigenetic inheritance. The increasing evidence implicates epigenetic changes as a primary impetus in disease development. The epigenetic regulation alters gene expression to promote compensatory adjustments in me ...
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2002
Bridging the gap between the molecular biology of cancer and clinical diagnosis and treatment, this online reference work provides a resource for medical and life sciences students, as well as all scientists, clinicians and researchers ... ...
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https://orcid.org/0000-0001-8298-7272