Scholars@Duke
Susan Kay Murphy

Susan Kay Murphy

Associate Professor Emeritus in Obstetrics and Gynecology
Obstetrics and Gynecology, Reproductive Sciences
Duke PO Box 90534, the Chesterfield Building, Durham, NC 27701
701 W. Main Street, Suite 510, Room 5140, Durham, NC 27701

Scholarly Works - Conferences

Abstract 4803: Ascites protects against ferroptosis and enables the peritoneal spread of ovarian cancer

Conference Cancer Research · April 3, 2026 AbstractOne of the most common sites of metastasis in ovarian cancer (OVCA) is the peritoneum. Often, this spread is accompanied by the accumulation of a fluid called ascites in the peritoneal cavity. Des ... Full text Cite

Paternal Cannabis Exposure Elicits Sex-Specific Cardiac Alterations in Offspring

Conference ENVIRONMENTAL AND MOLECULAR MUTAGENESIS · September 2025 Link to item Cite

Cross-Generational Impact of Cannabis on the Sperm Epigenome

Conference ENVIRONMENTAL AND MOLECULAR MUTAGENESIS · September 2024 Link to item Cite

TFAM as a mitochondrial DNA damage sensor

Conference ENVIRONMENTAL AND MOLECULAR MUTAGENESIS · September 2023 Link to item Cite

Maternal diet disrupts the placenta-brain axis in a sex-specific manner

Conference Brain, Behavior, and Immunity · November 2022 Full text Cite

Environment and Gametic Epigenetic Reprogramming.

Conference ENVIRONMENTAL AND MOLECULAR MUTAGENESIS · September 1, 2017 Link to item Cite

Abstract 1991: Enhanced role of the extracellular matrix in ovarian cancer recurrence

Conference Cancer Research · July 1, 2017 AbstractPurpose: Despite improvements in care and advancements in the understanding of ovarian cancer (OC) pathobiology and genetic alterations, the survival rate is disappointingly low when compared to that ... Full text Cite

STANDARDIZATION OF RNA PROCESSING FROM URINE SEDIMENT IN A CLINICAL SETTING

Conference NEUROUROLOGY AND URODYNAMICS · February 1, 2017 Link to item Cite

Environmental Influence on Preconceptional and Gestational DNA Methylation Profiles.

Conference ENVIRONMENTAL AND MOLECULAR MUTAGENESIS · September 1, 2016 Link to item Cite

Abstract B63: Expression of VEGF in ovarian cancer suppresses tumor immunity through recruitment of myeloid derived suppressor cells.

Conference Clinical Cancer Research · January 15, 2016 AbstractBackground and Objective: High expression of VEGF in ovarian cancer is a known unfavorable prognostic factor. However, its role in tumor immunity remains unclear. In this study, the impact of VEGF on ... Full text Cite

Abstract POSTER-BIOL-1319: Temporal shifts in the epigenetic regulation of tight junctions from primary to recurrent ovarian cancer

Conference Clinical Cancer Research · August 15, 2015 AbstractPurpose: Despite a complete clinical response following treatment with surgery and first-line chemotherapy, about 70-90% of patients with advanced stage ovarian cancer (OC) will inevitably experience ... Full text Cite

Abstract 2236: Emergence of epigenetic regulation of tight junction genes in recurrent serous epithelial ovarian cancer

Conference Cancer Research · August 1, 2015 AbstractPurpose: Despite a complete clinical response following treatment with surgery and first-line chemotherapy, about 70-90% of advanced ovarian cancer (OC) patients experience cancer recurrence. Our obj ... Full text Cite

Abstract 3912: GDF2 promotes anoikis susceptibility in ovarian and breast epithelia

Conference Cancer Research · August 1, 2015 AbstractResistance to anchorage independent cell death (anoikis) is one of the features of metastasis and can be regulated by a diverse array of growth factors. The protein encoded by GDF2 is BMP9 and is a m ... Full text Cite

Abstract 4570: Role of ERRalpha in ovarian cancer

Conference Cancer Research · October 1, 2014 AbstractObjective. The estrogen receptor-related receptor-alpha (ERRα, encoded by ESRRA) has emerged as a key transcriptional regulator of mitochondrial function and has been implicated as a prognostic marke ... Full text Cite

Abstract LB-123: Novel function of STAT1 pathway as a modulator of tumor progression in serous papillary endometrial cancer

Conference Cancer Research · October 1, 2014 AbstractSerous papillary endometrial cancers (SPEC) are highly progressive with poor prognosis, and its oncogenic profile is known different from endometrioid endometrial cancers. It, however, still remains ... Full text Cite

Abstract 4767: Preclinical mouse model of recurrent epithelial ovarian cancer.

Conference Cancer Research · April 15, 2013 AbstractPurpose: Most women diagnosed with advanced stage serous epithelial ovarian cancer exhibit a complete clinical response to surgical debulking and platinum-based chemotherapy. Remission can last month ... Full text Cite

Abstract 3647: Dose-dependent alteration of CpG methylation in AHRR and GFI1 in mononuclear cell DNA of smokers.

Conference Cancer Research · April 15, 2013 AbstractAbout 45 million (∼19%) of U.S. adults smoke, 46 million are former smokers and >100 million are exposed to environmental tobacco smoke. Tobacco use is associated with many types of cancer, he ... Full text Cite

Epigenetic Regulation of Gene Expression in NAFLD

Conference GASTROENTEROLOGY · May 1, 2012 Link to item Cite

Metastin-10 suppresses invasion of endometrial cancer cells

Conference GYNECOLOGIC ONCOLOGY · March 1, 2010 Link to item Cite

70: Epigenetic orchestration of circulating insulin-like growth factor-2 levels in cord blood

Conference American Journal of Obstetrics and Gynecology · December 2009 Full text Cite

YY1 imprint status and role in ovarian carcinogenesis

Conference CANCER RESEARCH · April 1, 2006 Link to item Cite

Trinucleotide repeat polymorphisms in the androgen receptor gene and risk of ovarian cancer.

Conference CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION · November 1, 2004 Link to item Cite