Svati Hasmukh Shah
Professor of Medicine
Current Appointments & Affiliations
- Professor of Medicine, Medicine, Cardiology, Medicine 2019
- Member in the Duke Clinical Research Institute, Duke Clinical Research Institute, Institutes and Centers 2010
- Member of Duke Molecular Physiology Institute, Duke Molecular Physiology Institute, Duke Molecular Physiology Institute 2013
Contact Information
- DUMC Box 3445, Durham, NC 27710
- Duke Box 104775, Durham, NC 27701
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svati.shah@duke.edu
(919) 684-1808
- Background
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Education, Training, & Certifications
- Fellow in Cardiology, Medicine, Duke University 2001 - 2005
- Medical Resident, Medicine, Children's Hospital Boston 1998 - 2001
- M.D., University of Washington 1998
- M.H.S., Johns Hopkins University 1994
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Duke Appointment History
- Associate Professor of Medicine, Medicine, Cardiology, Medicine 2015 - 2019
- Associate Research Professor of Global Health, Duke Global Health Institute, University Institutes and Centers 2011 - 2015
- Associate Professor of Medicine, Medicine, Cardiology, Medicine 2012 - 2015
- Associate Professor in the School of Nursing, School of Nursing, Duke University 2012 - 2013
- Assistant Professor of Medicine, Medicine, Cardiology, Medicine 2005 - 2011
- Assistant Professor in the School of Nursing, School of Nursing, Duke University 2007 - 2011
- Instructor, Temporary in the Department of Medicine, Medicine, Cardiology, Medicine 2005
- Recognition
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In the News
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NOV 6, 2015 -
JAN 13, 2014
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Awards & Honors
- Expertise
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Global Scholarship
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Research
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- Research
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Selected Grants
- Postdoctoral Training in Cardiovascular Clinical Research awarded by National Institutes of Health 2003 - 2024
- The Branched Chain Ketoacid Dehydrogenase Kinase-Phosphatase System as a New Regulatory Node in Myocardial Fuel Section awarded by National Institutes of Health 2018 - 2023
- A Clinic-Based Behavioral Intervention to Reduce Cardiovascular Disease Risk in Persons Living with HIV awarded by National Institutes of Health 2018 - 2022
- Duke Resident Physician-Scientist Program- NHLBI awarded by National Institutes of Health 2018 - 2022
- An integrated and diverse genomic medicine program for undiagnosed diseases awarded by National Institutes of Health 2014 - 2022
- Duke Training Grant in Nephrology awarded by National Institutes of Health 1995 - 2022
- Postdoctoral Training in Genomic Medicine Research awarded by National Institutes of Health 2017 - 2022
- Bioinformatics and Computational Biology Training Program awarded by National Institutes of Health 2005 - 2021
- Analysis of NMR lipoprotein and metabolite data of plasma obtained from CATHGEN and STRRIDE study participants awarded by Liposcience Inc. 2017 - 2021
- Multidisciplinary Heart and Vascular Diseases awarded by National Institutes of Health 1975 - 2021
- A Personalized Metabolomic Approach to Human Obesity and Weight Loss awarded by National Institutes of Health 2016 - 2019
- Urine TCA-Cycle Organic Anions in Diabetic Kidney Disease awarded by Augusta University 2018 - 2019
- Metabolomic Biomarkers Predictores of Long-term Success Following Bariatric Surgery awarded by Columbia University 2015 - 2019
- Endocrinology and Metabolism Training Program awarded by National Institutes of Health 2014 - 2019
- Integrated Biostatistical Training for CVD Research awarded by North Carolina State University 2017 - 2019
- Biomarkers of Mental Stress Induced Myocardial Ischemia and CHD Prognosis awarded by National Institutes of Health 2014 - 2019
- Collaborative Study on Biomarkers of Fatty Liver Diseases awarded by Pfizer, Inc. 2017 - 2018
- Systems Biology Approaches for Predicting Cardiometabolic Risk in Persons Living with HIV awarded by National Institutes of Health 2015 - 2018
- Air Quality by Genomics Interactions in a Cardiovascular Disease Cohort awarded by Health Effects Institute 2014 - 2017
- Risk Factors for Sudden Cardiac Death in Patients with Chronic Kidney Disease awarded by National Institutes of Health 2014 - 2017
- Metabolomic Quantitative Trait Locus (mQTL) Genetic Mapping in Human CVD awarded by National Institutes of Health 2009 - 2016
- Metabolic Regulators of Insulin Secretion and Insulin Resistance awarded by National Institutes of Health 2013 - 2015
- Expanding Evidence of Genetic Contributions to Survivorship in CAD awarded by National Institutes of Health 2011 - 2014
- Genetic Mediators of Metabolic Cardiovascular Disease Risk awarded by National Institutes of Health 2009 - 2012
- Survival and Age Biases in Gene Associations with Coronary Disease awarded by National Institutes of Health 2009 - 2011
- Genetic Epidemiology of Pelvic Organ Prolapse awarded by National Institutes of Health 2009 - 2011
- Molecular Genetics of Muscle Specialization awarded by National Institutes of Health 2001 - 2009
- Publications & Artistic Works
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Selected Publications
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Academic Articles
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Harskamp, Ralf E., Thomas M. Granger, Robert M. Clare, Kyle R. White, Renato D. Lopes, Karen S. Pieper, Christopher B. Granger, Christopher B. Newgard, Svati H. Shah, and L Kristin Newby. “Peripheral blood metabolite profiles associated with new onset atrial fibrillation..” Am Heart J 211 (May 2019): 54–59. https://doi.org/10.1016/j.ahj.2019.01.010.Full Text Link to Item
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Benjamin, Emelia J., Paul Muntner, Alvaro Alonso, Marcio S. Bittencourt, Clifton W. Callaway, April P. Carson, Alanna M. Chamberlain, et al. “Heart Disease and Stroke Statistics-2019 Update: A Report From the American Heart Association..” Circulation 139, no. 10 (March 2019): e56–528. https://doi.org/10.1161/cir.0000000000000659.Full Text
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Pagidipati, Neha J., Adrian Coles, Kshipra Hemal, Kerry L. Lee, Rowena J. Dolor, Patricia A. Pellikka, Daniel B. Mark, et al. “Sex differences in management and outcomes of patients with stable symptoms suggestive of coronary artery disease: Insights from the PROMISE trial..” American Heart Journal 208 (February 2019): 28–36. https://doi.org/10.1016/j.ahj.2018.11.002.Full Text
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Dhingra, Radhika, Lydia Coulter Kwee, David Diaz-Sanchez, Robert B. Devlin, Wayne Cascio, Elizabeth R. Hauser, Simon Gregory, et al. “Evaluating DNA methylation age on the Illumina MethylationEPIC Bead Chip..” Plos One 14, no. 4 (2019). https://doi.org/10.1371/journal.pone.0207834.Full Text Link to Item
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Hunter, Wynn G., Robert W. McGarrah, Jacob P. Kelly, Michel G. Khouri, Damian M. Craig, Carol Haynes, G Michael Felker, et al. “High-Density Lipoprotein Particle Subfractions in Heart Failure With Preserved or Reduced Ejection Fraction..” Journal of the American College of Cardiology 73, no. 2 (January 2019): 177–86. https://doi.org/10.1016/j.jacc.2018.10.059.Full Text
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Limkakeng, Alexander T., Ricardo Henao, Deepak Voora, Thomas O’Connell, Michelle Griffin, Ephraim L. Tsalik, Svati Shah, Christopher W. Woods, and Geoffrey S. Ginsburg. “Pilot study of myocardial ischemia-induced metabolomic changes in emergency department patients undergoing stress testing..” Plos One 14, no. 2 (January 2019). https://doi.org/10.1371/journal.pone.0211762.Full Text
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Abraham, Dennis M., Teresa E. Lee, Lewis J. Watson, Lan Mao, Gurangad Chandok, Hong-Gang Wang, Stephan Frangakis, et al. “The two-pore domain potassium channel TREK-1 mediates cardiac fibrosis and diastolic dysfunction..” The Journal of Clinical Investigation 128, no. 11 (November 2018): 4843–55. https://doi.org/10.1172/JCI95945.Full Text
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Okeke, Nwora Lance, Fawaz Alenezi, Gerald S. Bloomfield, Allison Dunning, Meredith E. Clement, Svati H. Shah, Susanna Naggie, and Eric J. Velazquez. “Determinants of Left Ventricular Hypertrophy and Diastolic Dysfunction in an HIV Clinical Cohort..” Journal of Cardiac Failure 24, no. 8 (August 2018): 496–503. https://doi.org/10.1016/j.cardfail.2018.06.003.Full Text
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Shantavasinkul, Prapimporn Chattranukulchai, Michael J. Muehlbauer, James R. Bain, Olga R. Ilkayeva, Damian M. Craig, Christopher B. Newgard, Laura P. Svetkey, Svati H. Shah, and Alfonso Torquati. “Improvement in insulin resistance after gastric bypass surgery is correlated with a decline in plasma 2-hydroxybutyric acid..” Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery 14, no. 8 (August 2018): 1126–32. https://doi.org/10.1016/j.soard.2018.03.033.Full Text
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Gusarova, Viktoria, Colm O’Dushlaine, Tanya M. Teslovich, Peter N. Benotti, Tooraj Mirshahi, Omri Gottesman, Cristopher V. Van Hout, et al. “Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes..” Nat Commun 9, no. 1 (June 13, 2018). https://doi.org/10.1038/s41467-018-04611-z.Full Text Link to Item
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Roselli, Carolina, Mark D. Chaffin, Lu-Chen Weng, Stefanie Aeschbacher, Gustav Ahlberg, Christine M. Albert, Peter Almgren, et al. “Multi-ethnic genome-wide association study for atrial fibrillation..” Nat Genet 50, no. 9 (June 11, 2018): 1225–33. https://doi.org/10.1038/s41588-018-0133-9.Full Text Link to Item
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Musunuru, Kiran, Pankaj Arora, John P. Cooke, Jane F. Ferguson, Ray E. Hershberger, Kathleen T. Hickey, Jin-Moo Lee, et al. “Interdisciplinary Models for Research and Clinical Endeavors in Genomic Medicine: A Scientific Statement From the American Heart Association..” Circ Genom Precis Med 11, no. 6 (June 2018). https://doi.org/10.1161/HCG.0000000000000046.Full Text Link to Item
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Hayes, Sharonne N., Esther S. H. Kim, Jacqueline Saw, David Adlam, Cynthia Arslanian-Engoren, Katherine E. Economy, Santhi K. Ganesh, et al. “Spontaneous Coronary Artery Dissection: Current State of the Science: A Scientific Statement From the American Heart Association..” Circulation 137, no. 19 (May 2018): e523–57. https://doi.org/10.1161/CIR.0000000000000564.Full Text
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Turcot, Valérie, Yingchang Lu, Heather M. Highland, Claudia Schurmann, Anne E. Justice, Rebecca S. Fine, Jonathan P. Bradfield, et al. “Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity..” Nature Genetics 50, no. 5 (May 2018): 765–66. https://doi.org/10.1038/s41588-018-0050-y.Full Text
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Turcot, Valérie, Yingchang Lu, Heather M. Highland, Claudia Schurmann, Anne E. Justice, Rebecca S. Fine, Jonathan P. Bradfield, et al. “Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity..” Nature Genetics 50, no. 5 (May 2018): 766–67. https://doi.org/10.1038/s41588-018-0082-3.Full Text
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McGarrah, Robert W., Scott B. Crown, Guo-Fang Zhang, Svati H. Shah, and Christopher B. Newgard. “Cardiovascular Metabolomics..” Circ Res 122, no. 9 (April 27, 2018): 1238–58. https://doi.org/10.1161/CIRCRESAHA.117.311002.Full Text Link to Item
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Butler, Javed, Andreas P. Kalogeropoulos, Kevin J. Anstrom, Priscilla Y. Hsue, Raymond J. Kim, Rebecca Scherzer, Sanjiv J. Shah, et al. “Diastolic Dysfunction in Individuals With Human Immunodeficiency Virus Infection: Literature Review, Rationale and Design of the Characterizing Heart Function on Antiretroviral Therapy (CHART) Study..” Journal of Cardiac Failure 24, no. 4 (April 2018): 255–65. https://doi.org/10.1016/j.cardfail.2018.02.001.Full Text
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Denus, S. de, J. L. Rouleau, D. L. Mann, G. S. Huggins, N. L. Pereira, S. H. Shah, T. P. Cappola, R. Fouodjio, I. Mongrain, and M. -. P. Dubé. “CYP3A4 genotype is associated with sildenafil concentrations in patients with heart failure with preserved ejection fraction..” The Pharmacogenomics Journal 18, no. 2 (April 2018): 232–37. https://doi.org/10.1038/tpj.2017.8.Full Text
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Benjamin, Emelia J., Salim S. Virani, Clifton W. Callaway, Alanna M. Chamberlain, Alexander R. Chang, Susan Cheng, Stephanie E. Chiuve, et al. “Heart Disease and Stroke Statistics-2018 Update: A Report From the American Heart Association..” Circulation 137, no. 12 (March 20, 2018): e67–492. https://doi.org/10.1161/CIR.0000000000000558.Full Text Link to Item
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McGarrah, Robert W., and Svati H. Shah. “Integrative Omics: Harnessing the Proteome to Maximize the Potential of the Genome..” Circulation 137, no. 11 (March 2018): 1173–75. https://doi.org/10.1161/circulationaha.117.032807.Full Text
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Okeke, Nwora Lance, Damian M. Craig, Michael J. Muehlbauer, Olga Ilkayeva, Meredith E. Clement, Susanna Naggie, and Svati H. Shah. “Metabolites predict cardiovascular disease events in persons living with HIV: a pilot case-control study..” Metabolomics : Official Journal of the Metabolomic Society 14, no. 3 (March 2018). https://doi.org/10.1007/s11306-018-1318-z.Full Text
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Brummett, Beverly H., Michael A. Babyak, Abanish Singh, Elizabeth R. Hauser, Rong Jiang, Kim M. Huffman, William E. Kraus, Svati H. Shah, Ilene C. Siegler, and Redford B. Williams. “Lack of Association of a Functional Polymorphism in the Serotonin Receptor Gene With Body Mass Index and Depressive Symptoms in a Large Meta-Analysis of Population Based Studies..” Frontiers in Genetics 9 (January 2018). https://doi.org/10.3389/fgene.2018.00423.Full Text
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Turcot, Valérie, Yingchang Lu, Heather M. Highland, Claudia Schurmann, Anne E. Justice, Rebecca S. Fine, Jonathan P. Bradfield, et al. “Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity..” Nat Genet 50, no. 1 (January 2018): 26–41. https://doi.org/10.1038/s41588-017-0011-x.Full Text Link to Item
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Ward-Caviness, Cavin K., William E. Kraus, Colette Blach, Carol S. Haynes, Elaine Dowdy, Marie Lynn Miranda, Robert Devlin, et al. “Associations Between Residential Proximity to Traffic and Vascular Disease in a Cardiac Catheterization Cohort..” Arteriosclerosis, Thrombosis, and Vascular Biology 38, no. 1 (January 2018): 275–82. https://doi.org/10.1161/ATVBAHA.117.310003.Full Text
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Schormair, Barbara, Chen Zhao, Steven Bell, Erik Tilch, Aaro V. Salminen, Benno Pütz, Yves Dauvilliers, et al. “Identification of novel risk loci for restless legs syndrome in genome-wide association studies in individuals of European ancestry: a meta-analysis..” The Lancet. Neurology 16, no. 11 (November 2017): 898–907. https://doi.org/10.1016/S1474-4422(17)30327-7.Full Text
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Shah, Svati H., and Wynn G. Hunter. “Realizing the Potential of Metabolomics in Heart Failure: Signposts on the Path to Clinical Utility..” Jacc. Heart Failure 5, no. 11 (November 2017): 833–36. https://doi.org/10.1016/j.jchf.2017.08.025.Full Text
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Wang, Hanghang, Michael J. Muehlbauer, Sara K. O’Neal, Christopher B. Newgard, Elizabeth R. Hauser, James R. Bain, and Svati H. Shah. “Recommendations for Improving Identification and Quantification in Non-Targeted, GC-MS-Based Metabolomic Profiling of Human Plasma..” Metabolites 7, no. 3 (August 25, 2017). https://doi.org/10.3390/metabo7030045.Full Text
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Jiang, Rong, Michael A. Babyak, Beverly H. Brummett, Elizabeth R. Hauser, Svati H. Shah, Richard C. Becker, Ilene C. Siegler, et al. “Brain-derived neurotrophic factor rs6265 (Val66Met) polymorphism is associated with disease severity and incidence of cardiovascular events in a patient cohort..” American Heart Journal 190 (August 2017): 40–45. https://doi.org/10.1016/j.ahj.2017.05.002.Full Text
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Wang, Hanghang, Kevin Anstrom, Olga Ilkayeva, Michael J. Muehlbauer, James R. Bain, Steven McNulty, Christopher B. Newgard, et al. “Sildenafil Treatment in Heart Failure With Preserved Ejection Fraction: Targeted Metabolomic Profiling in the RELAX Trial..” Jama Cardiology 2, no. 8 (August 2017): 896–901. https://doi.org/10.1001/jamacardio.2017.1239.Full Text
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Lawler, Patrick R., Akintunde O. Akinkuolie, Audrey Y. Chu, Svati H. Shah, William E. Kraus, Damian Craig, Latha Padmanabhan, et al. “Atherogenic Lipoprotein Determinants of Cardiovascular Disease and Residual Risk Among Individuals With Low Low-Density Lipoprotein Cholesterol..” J Am Heart Assoc 6, no. 7 (July 21, 2017). https://doi.org/10.1161/JAHA.117.005549.Full Text Link to Item
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Dewey, Frederick E., Viktoria Gusarova, Richard L. Dunbar, Colm O’Dushlaine, Claudia Schurmann, Omri Gottesman, Shane McCarthy, et al. “Genetic and Pharmacologic Inactivation of ANGPTL3 and Cardiovascular Disease..” The New England Journal of Medicine 377, no. 3 (July 2017): 211–21. https://doi.org/10.1056/NEJMoa1612790.Full Text
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Christophersen, Ingrid E., Michiel Rienstra, Carolina Roselli, Xiaoyan Yin, Bastiaan Geelhoed, John Barnard, Honghuang Lin, et al. “Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation..” Nature Genetics 49, no. 6 (June 2017): 946–52. https://doi.org/10.1038/ng.3843.Full Text
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Guimarães, Patrícia O., Jie-Lena Sun, Kristian Kragholm, Svati H. Shah, Karen S. Pieper, William E. Kraus, Elizabeth R. Hauser, Christopher B. Granger, L. Kristin Newby, and L. MURDOCK Horizon 1 Cardiovascular Study Investigators Durham, NC. “Corrigendum to 'Association of Standard Clinical and Laboratory Variables with Red Blood Cell Distribution Width (RDW)'[Am. Heart J. (2016) 22-28]..” American Heart Journal 188 (June 2017). https://doi.org/10.1016/j.ahj.2017.05.011.Full Text
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Saleheen, Danish, Wei Zhao, Robin Young, Christopher P. Nelson, WeangKee Ho, Jane F. Ferguson, Asif Rasheed, et al. “Loss of Cardioprotective Effects at the ADAMTS7 Locus as a Result of Gene-Smoking Interactions..” Circulation 135, no. 24 (June 2017): 2336–53. https://doi.org/10.1161/CIRCULATIONAHA.116.022069.Full Text
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Wang, Alice, Lydia Coulter Kwee, Elizabeth Grass, Megan L. Neely, Simon G. Gregory, Keith A. A. Fox, Paul W. Armstrong, et al. “Whole blood sequencing reveals circulating microRNA associations with high-risk traits in non-ST-segment elevation acute coronary syndrome..” Atherosclerosis 261 (June 2017): 19–25. https://doi.org/10.1016/j.atherosclerosis.2017.03.041.Full Text
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Mirowsky, Jaime E., Robert B. Devlin, David Diaz-Sanchez, Wayne Cascio, Shannon C. Grabich, Carol Haynes, Colette Blach, et al. “A novel approach for measuring residential socioeconomic factors associated with cardiovascular and metabolic health..” Journal of Exposure Science & Environmental Epidemiology 27, no. 3 (May 2017): 281–89. https://doi.org/10.1038/jes.2016.53.Full Text
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Stitziel, Nathan O., Amit V. Khera, Xiao Wang, Andrew J. Bierhals, A Christina Vourakis, Alexandra E. Sperry, Pradeep Natarajan, et al. “ANGPTL3 Deficiency and Protection Against Coronary Artery Disease..” J Am Coll Cardiol 69, no. 16 (April 25, 2017): 2054–63. https://doi.org/10.1016/j.jacc.2017.02.030.Full Text Link to Item
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Cheng, Susan, Svati H. Shah, Elizabeth J. Corwin, Oliver Fiehn, Robert L. Fitzgerald, Robert E. Gerszten, Thomas Illig, et al. “Potential Impact and Study Considerations of Metabolomics in Cardiovascular Health and Disease: A Scientific Statement From the American Heart Association..” Circulation. Cardiovascular Genetics 10, no. 2 (April 2017). https://doi.org/10.1161/HCG.0000000000000032.Full Text
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Luo, Nancy, Damian Craig, Olga Ilkayeva, Michael Muehlbauer, William E. Kraus, Christopher B. Newgard, Svati H. Shah, and Sudarshan Rajagopal. “Plasma acylcarnitines are associated with pulmonary hypertension..” Pulmonary Circulation 7, no. 1 (March 2017): 211–18. https://doi.org/10.1086/690554.Full Text
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Webb, Thomas R., Jeanette Erdmann, Kathleen E. Stirrups, Nathan O. Stitziel, Nicholas G. D. Masca, Henning Jansen, Stavroula Kanoni, et al. “Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease..” J Am Coll Cardiol 69, no. 7 (February 21, 2017): 823–36. https://doi.org/10.1016/j.jacc.2016.11.056.Full Text Link to Item
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Marouli, Eirini, Mariaelisa Graff, Carolina Medina-Gomez, Ken Sin Lo, Andrew R. Wood, Troels R. Kjaer, Rebecca S. Fine, et al. “Rare and low-frequency coding variants alter human adult height..” Nature 542, no. 7640 (February 9, 2017): 186–90. https://doi.org/10.1038/nature21039.Full Text Link to Item
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Voora, Deepak, Adrian Coles, Kerry L. Lee, Udo Hoffmann, James A. Wingrove, Brian Rhees, Lin Huang, et al. “An age- and sex-specific gene expression score is associated with revascularization and coronary artery disease: Insights from the Prospective Multicenter Imaging Study for Evaluation of Chest Pain (PROMISE) trial..” American Heart Journal 184 (February 2017): 133–40. https://doi.org/10.1016/j.ahj.2016.11.004.Full Text
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Wang, Hanghang, Patrick H. Pun, Lydia Kwee, Damian Craig, Carol Haynes, Megan Chryst-Ladd, Laura P. Svetkey, et al. “Apolipoprotein L1 Genetic Variants Are Associated with Chronic Kidney Disease but Not with Cardiovascular Disease in a Population Referred for Cardiac Catheterization..” Cardiorenal Medicine 7, no. 2 (February 2017): 96–103. https://doi.org/10.1159/000453458.Full Text
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Brænne, Ingrid, Lingyao Zeng, Christina Willenborg, Vinicius Tragante, Thorsten Kessler, Thorsten CARDIoGRAM Consortium, Thorsten CARDIoGRAMplusC4D Consortium, et al. “Genomic correlates of glatiramer acetate adverse cardiovascular effects lead to a novel locus mediating coronary risk..” Plos One 12, no. 8 (January 2017). https://doi.org/10.1371/journal.pone.0182999.Full Text
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McGarrah, Robert W., Jacob P. Kelly, Damian M. Craig, Carol Haynes, Ryan C. Jessee, Kim M. Huffman, William E. Kraus, and Svati H. Shah. “A Novel Protein Glycan-Derived Inflammation Biomarker Independently Predicts Cardiovascular Disease and Modifies the Association of HDL Subclasses with Mortality..” Clinical Chemistry 63, no. 1 (January 2017): 288–96. https://doi.org/10.1373/clinchem.2016.261636.Full Text
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Ward-Caviness, Cavin K., Lucas M. Neas, Colette Blach, Carol S. Haynes, Karen LaRocque-Abramson, Elizabeth Grass, Z Elaine Dowdy, et al. “A genome-wide trans-ethnic interaction study links the PIGR-FCAMR locus to coronary atherosclerosis via interactions between genetic variants and residential exposure to traffic..” Plos One 12, no. 3 (January 2017). https://doi.org/10.1371/journal.pone.0173880.Full Text
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Breitner, Susanne, Alexandra Schneider, Robert B. Devlin, Cavin K. Ward-Caviness, David Diaz-Sanchez, Lucas M. Neas, Wayne E. Cascio, et al. “Associations among plasma metabolite levels and short-term exposure to PM2.5 and ozone in a cardiac catheterization cohort..” Environment International 97 (December 2016): 76–84. https://doi.org/10.1016/j.envint.2016.10.012.Full Text
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Nüesch, Eveline, Caroline Dale, Tom M. Palmer, Jon White, Brendan J. Keating, Erik Pa van Iperen, Anuj Goel, et al. “Adult height, coronary heart disease and stroke: a multi-locus Mendelian randomization meta-analysis..” International Journal of Epidemiology 45, no. 6 (December 2016): 1927–37. https://doi.org/10.1093/ije/dyv074.Full Text
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Hampel, Regina, Susanne Breitner, William E. Kraus, Elizabeth Hauser, Svati Shah, Cavin K. Ward-Caviness, Robert Devlin, et al. “Short-term effects of air temperature on plasma metabolite concentrations in patients undergoing cardiac catheterization..” Environmental Research 151 (November 2016): 224–32. https://doi.org/10.1016/j.envres.2016.07.010.Full Text
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Loley, Christina, Maris Alver, Themistocles L. Assimes, Andrew Bjonnes, Anuj Goel, Stefan Gustafsson, Jussi Hernesniemi, et al. “No Association of Coronary Artery Disease with X-Chromosomal Variants in Comprehensive International Meta-Analysis..” Scientific Reports 6 (October 12, 2016). https://doi.org/10.1038/srep35278.Full Text
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McGarrah, Robert W., and Svati H. Shah. “Exomes, Proteins, and Cardiovascular Disease: Making Sense of the Signals..” Circulation. Cardiovascular Genetics 9, no. 4 (August 2016): 318–19. https://doi.org/10.1161/circgenetics.116.001549.Full Text
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Hunter, Wynn G., Jacob P. Kelly, Robert W. McGarrah, Michel G. Khouri, Damian Craig, Carol Haynes, Olga Ilkayeva, et al. “Metabolomic Profiling Identifies Novel Circulating Biomarkers of Mitochondrial Dysfunction Differentially Elevated in Heart Failure With Preserved Versus Reduced Ejection Fraction: Evidence for Shared Metabolic Impairments in Clinical Heart Failure..” J Am Heart Assoc 5, no. 8 (July 29, 2016). https://doi.org/10.1161/JAHA.115.003190.Full Text Open Access Copy Link to Item
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Samad, Zainab, Amit N. Vora, Allison Dunning, Phillip J. Schulte, Linda K. Shaw, Fawaz Al-Enezi, Mads Ersboll, et al. “Aortic valve surgery and survival in patients with moderate or severe aortic stenosis and left ventricular dysfunction..” European Heart Journal 37, no. 28 (July 2016): 2276–86. https://doi.org/10.1093/eurheartj/ehv701.Full Text
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Pagidipati, Neha J., Kshipra Hemal, Adrian Coles, Daniel B. Mark, Rowena J. Dolor, Patricia A. Pellikka, Udo Hoffmann, et al. “Sex Differences in Functional and CT Angiography Testing in Patients With Suspected Coronary Artery Disease..” J Am Coll Cardiol 67, no. 22 (June 7, 2016): 2607–16. https://doi.org/10.1016/j.jacc.2016.03.523.Full Text Link to Item
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Hunter, Wynn G., Jacob P. Kelly, Robert W. McGarrah, William E. Kraus, and Svati H. Shah. “Metabolic Dysfunction in Heart Failure: Diagnostic, Prognostic, and Pathophysiologic Insights From Metabolomic Profiling..” Current Heart Failure Reports 13, no. 3 (June 2016): 119–31. https://doi.org/10.1007/s11897-016-0289-5.Full Text
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Nioi, Paul, Asgeir Sigurdsson, Gudmar Thorleifsson, Hannes Helgason, Arna B. Agustsdottir, Gudmundur L. Norddahl, Anna Helgadottir, et al. “Variant ASGR1 Associated with a Reduced Risk of Coronary Artery Disease..” The New England Journal of Medicine 374, no. 22 (June 2016): 2131–41. https://doi.org/10.1056/nejmoa1508419.Full Text
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Sun, Haipeng, Kristine C. Olson, Chen Gao, Domenick A. Prosdocimo, Meiyi Zhou, Zhihua Wang, Darwin Jeyaraj, et al. “Catabolic Defect of Branched-Chain Amino Acids Promotes Heart Failure..” Circulation 133, no. 21 (May 24, 2016): 2038–49. https://doi.org/10.1161/CIRCULATIONAHA.115.020226.Full Text Link to Item
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Guimarães, Patrícia O., Jie-Lena Sun, Kristian Kragholm, Svati H. Shah, Karen S. Pieper, William E. Kraus, Elizabeth R. Hauser, Christopher B. Granger, L Kristin Newby, and L Kristin MURDOCK Horizon 1 Cardiovascular Study Investigators. “Association of standard clinical and laboratory variables with red blood cell distribution width..” Am Heart J 174 (April 2016): 22–28. https://doi.org/10.1016/j.ahj.2016.01.001.Full Text Link to Item
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Hemal, Kshipra, Neha J. Pagidipati, Adrian Coles, Rowena J. Dolor, Daniel B. Mark, Patricia A. Pellikka, Udo Hoffmann, et al. “Sex Differences in Demographics, Risk Factors, Presentation, and Noninvasive Testing in Stable Outpatients With Suspected Coronary Artery Disease: Insights From the PROMISE Trial..” Jacc. Cardiovascular Imaging 9, no. 4 (April 2016): 337–46. https://doi.org/10.1016/j.jcmg.2016.02.001.Full Text
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Pereira, Naveen L., Jeffrey B. Geske, Manuel Mayr, Svati H. Shah, and Charanjit S. Rihal. “Pharmacogenetics of Clopidogrel: An Unresolved Issue..” Circulation. Cardiovascular Genetics 9, no. 2 (April 2016): 185–88. https://doi.org/10.1161/circgenetics.115.001318.Full Text
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Myocardial Infarction Genetics and CARDIoGRAM Exome Consortia Investigators, Heribert, Nathan O. Stitziel, Kathleen E. Stirrups, Nicholas G. D. Masca, Jeanette Erdmann, Paola G. Ferrario, Inke R. König, et al. “Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease..” N Engl J Med 374, no. 12 (March 24, 2016): 1134–44. https://doi.org/10.1056/NEJMoa1507652.Full Text Link to Item
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McGarrah, Robert W., Damian M. Craig, Carol Haynes, Z Elaine Dowdy, Svati H. Shah, and William E. Kraus. “High-density lipoprotein subclass measurements improve mortality risk prediction, discrimination and reclassification in a cardiac catheterization cohort..” Atherosclerosis 246 (March 2016): 229–35. https://doi.org/10.1016/j.atherosclerosis.2016.01.012.Full Text
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Voora, Deepak, and Svati H. Shah. “Pharmacometabolomics Meets Genetics: A "Natural" Clinical Trial of Statin Effects..” Journal of the American College of Cardiology 67, no. 10 (March 2016): 1211–13. https://doi.org/10.1016/j.jacc.2016.01.022.Full Text
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Wolf, Matthew J., Dagny Noeth, Chidambaram Rammohan, and Svati H. Shah. “Complexities of Genetic Testing in Familial Dilated Cardiomyopathy..” Circulation. Cardiovascular Genetics 9, no. 1 (February 2016): 95–99. https://doi.org/10.1161/CIRCGENETICS.115.001157.Full Text
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Ahmad, Tariq, Jacob P. Kelly, Robert W. McGarrah, Anne S. Hellkamp, Mona Fiuzat, Jeffrey M. Testani, Teresa S. Wang, et al. “Prognostic Implications of Long-Chain Acylcarnitines in Heart Failure and Reversibility With Mechanical Circulatory Support..” Journal of the American College of Cardiology 67, no. 3 (January 2016): 291–99. https://doi.org/10.1016/j.jacc.2015.10.079.Full Text
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Dungan, Jennifer R., Xuejun Qin, Benjamin D. Horne, John F. Carlquist, Abanish Singh, Melissa Hurdle, Elizabeth Grass, et al. “Case-Only Survival Analysis Reveals Unique Effects of Genotype, Sex, and Coronary Disease Severity on Survivorship..” Plos One 11, no. 5 (January 2016). https://doi.org/10.1371/journal.pone.0154856.Full Text
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Shah, Svati H., Donna Arnett, Steven R. Houser, Geoffrey S. Ginsburg, Calum MacRae, Seema Mital, Joseph Loscalzo, and Jennifer L. Hall. “Opportunities for the Cardiovascular Community in the Precision Medicine Initiative..” Circulation 133, no. 2 (January 2016): 226–31. https://doi.org/10.1161/circulationaha.115.019475.Full Text
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Ward-Caviness, Cavin K., Lucas M. Neas, Colette Blach, Carol S. Haynes, Karen LaRocque-Abramson, Elizabeth Grass, Elaine Dowdy, et al. “Genetic Variants in the Bone Morphogenic Protein Gene Family Modify the Association between Residential Exposure to Traffic and Peripheral Arterial Disease..” Plos One 11, no. 4 (January 2016). https://doi.org/10.1371/journal.pone.0152670.Full Text
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Kraus, William E., Christopher B. Granger, Michael H. Sketch, Mark P. Donahue, Geoffrey S. Ginsburg, Elizabeth R. Hauser, Carol Haynes, et al. “A Guide for a Cardiovascular Genomics Biorepository: the CATHGEN Experience..” J Cardiovasc Transl Res 8, no. 8 (November 2015): 449–57. https://doi.org/10.1007/s12265-015-9648-y.Full Text Link to Item
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Kraus, William E., Deborah M. Muoio, Robert Stevens, Damian Craig, James R. Bain, Elizabeth Grass, Carol Haynes, et al. “Metabolomic Quantitative Trait Loci (mQTL) Mapping Implicates the Ubiquitin Proteasome System in Cardiovascular Disease Pathogenesis..” Plos Genet 11, no. 11 (November 2015). https://doi.org/10.1371/journal.pgen.1005553.Full Text Open Access Copy Link to Item
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Nikpay, Majid, Anuj Goel, Hong-Hee Won, Leanne M. Hall, Christina Willenborg, Stavroula Kanoni, Danish Saleheen, et al. “A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease..” Nature Genetics 47, no. 10 (October 2015): 1121–30. https://doi.org/10.1038/ng.3396.Full Text
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Stafford-Smith, Mark, Yi-Ju Li, Joseph P. Mathew, Yen-Wei Li, Yunqi Ji, Barbara G. Phillips-Bute, Carmelo A. Milano, et al. “Genome-wide association study of acute kidney injury after coronary bypass graft surgery identifies susceptibility loci..” Kidney International 88, no. 4 (October 2015): 823–32. https://doi.org/10.1038/ki.2015.161.Full Text Open Access Copy
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Ward-Caviness, Cavin K., William E. Kraus, Colette Blach, Carol S. Haynes, Elaine Dowdy, Marie Lynn Miranda, Robert B. Devlin, et al. “Association of Roadway Proximity with Fasting Plasma Glucose and Metabolic Risk Factors for Cardiovascular Disease in a Cross-Sectional Study of Cardiac Catheterization Patients..” Environmental Health Perspectives 123, no. 10 (October 2015): 1007–14. https://doi.org/10.1289/ehp.1306980.Full Text
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Burke, Lora E., Jun Ma, Kristen M. J. Azar, Gary G. Bennett, Eric D. Peterson, Yaguang Zheng, William Riley, et al. “Current Science on Consumer Use of Mobile Health for Cardiovascular Disease Prevention: A Scientific Statement From the American Heart Association..” Circulation 132, no. 12 (September 22, 2015): 1157–1213. https://doi.org/10.1161/CIR.0000000000000232.Full Text Link to Item
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Dokun, Ayotunde O., Lingdan Chen, Mitsuharu Okutsu, Charles R. Farber, Surovi Hazarika, W Schuyler Jones, Damian Craig, et al. “ADAM12: a genetic modifier of preclinical peripheral arterial disease..” Am J Physiol Heart Circ Physiol 309, no. 5 (September 2015): H790–803. https://doi.org/10.1152/ajpheart.00803.2014.Full Text Link to Item
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Kertai, Miklos D., Yi-Ju Li, Yunqi Ji, Wenjing Qi, Frederick W. Lombard, Svati H. Shah, William E. Kraus, et al. “Genome-wide association study of new-onset atrial fibrillation after coronary artery bypass grafting surgery..” American Heart Journal 170, no. 3 (September 2015): 580-90.e28. https://doi.org/10.1016/j.ahj.2015.06.009.Full Text
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Parikh, Kishan S., Sudarshan Rajagopal, Kristine Arges, Tariq Ahmad, Joseph Sivak, Prashant Kaul, Svati H. Shah, et al. “Use of outcome measures in pulmonary hypertension clinical trials..” American Heart Journal 170, no. 3 (September 2015): 419-29.e3. https://doi.org/10.1016/j.ahj.2015.06.010.Full Text
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Singh, Abanish, Michael A. Babyak, Beverly H. Brummett, Rong Jiang, Lana L. Watkins, John C. Barefoot, William E. Kraus, et al. “Computing a Synthetic Chronic Psychosocial Stress Measurement in Multiple Datasets and its Application in the Replication of G × E Interactions of the EBF1 Gene..” Genetic Epidemiology 39, no. 6 (September 2015): 489–97. https://doi.org/10.1002/gepi.21910.Full Text
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Shah, Asad A., Simon G. Gregory, Deidre Krupp, Sheng Feng, Allison Dorogi, Carol Haynes, Elizabeth Grass, et al. “Epigenetic profiling identifies novel genes for ascending aortic aneurysm formation with bicuspid aortic valves..” The Heart Surgery Forum 18, no. 4 (August 30, 2015): E134–39. https://doi.org/10.1532/hsf.1247.Full Text
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Ghosh, Sujoy, Juan Vivar, Christopher P. Nelson, Christina Willenborg, Ayellet V. Segrè, Ville-Petteri Mäkinen, Majid Nikpay, et al. “Systems Genetics Analysis of Genome-Wide Association Study Reveals Novel Associations Between Key Biological Processes and Coronary Artery Disease..” Arteriosclerosis, Thrombosis, and Vascular Biology 35, no. 7 (July 2015): 1712–22. https://doi.org/10.1161/ATVBAHA.115.305513.Full Text
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Singh, Abanish, Michael A. Babyak, Daniel K. Nolan, Beverly H. Brummett, Rong Jiang, Ilene C. Siegler, William E. Kraus, Svati H. Shah, Redford B. Williams, and Elizabeth R. Hauser. “Gene by stress genome-wide interaction analysis and path analysis identify EBF1 as a cardiovascular and metabolic risk gene..” European Journal of Human Genetics : Ejhg 23, no. 6 (June 2015): 854–62. https://doi.org/10.1038/ejhg.2014.189.Full Text
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Nelson, Christopher P., Stephen E. Hamby, Danish Saleheen, Jenna C. Hopewell, Lingyao Zeng, Themistocles L. Assimes, Stavroula Kanoni, et al. “Genetically determined height and coronary artery disease..” N Engl J Med 372, no. 17 (April 23, 2015): 1608–18. https://doi.org/10.1056/NEJMoa1404881.Full Text Link to Item
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Shah, Svati H., and Christopher B. Newgard. “Integrated metabolomics and genomics: systems approaches to biomarkers and mechanisms of cardiovascular disease..” Circulation. Cardiovascular Genetics 8, no. 2 (April 2015): 410–19. https://doi.org/10.1161/CIRCGENETICS.114.000223.Full Text
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Shah, Asad A., Carol Haynes, Damian M. Craig, Jacqueline Sebek, Elizabeth Grass, Karen Abramson, Elizabeth Hauser, et al. “Genetic variants associated with vein graft stenosis after coronary artery bypass grafting..” The Heart Surgery Forum 18, no. 1 (February 27, 2015): E1–5. https://doi.org/10.1532/hsf.1214.Full Text
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Do, Ron, Nathan O. Stitziel, Hong-Hee Won, Anders Berg Jørgensen, Stefano Duga, Pier Angelica Merlini, Adam Kiezun, et al. “Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction..” Nature 518, no. 7537 (February 5, 2015): 102–6. https://doi.org/10.1038/nature13917.Full Text Link to Item
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Halim, Sharif A., Megan L. Neely, Karen S. Pieper, Svati H. Shah, William E. Kraus, Elizabeth R. Hauser, Robert M. Califf, Christopher B. Granger, and L Kristin Newby. “Simultaneous consideration of multiple candidate protein biomarkers for long-term risk for cardiovascular events..” Circulation. Cardiovascular Genetics 8, no. 1 (February 2015): 168–77. https://doi.org/10.1161/CIRCGENETICS.113.000490.Full Text
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Ahmad, Tariq, Teresa Wang, Emily C. O’Brien, Marc D. Samsky, John A. Pura, Yuliya Lokhnygina, Joseph G. Rogers, et al. “Effects of left ventricular assist device support on biomarkers of cardiovascular stress, fibrosis, fluid homeostasis, inflammation, and renal injury..” Jacc Heart Fail 3, no. 1 (January 2015): 30–39. https://doi.org/10.1016/j.jchf.2014.06.013.Full Text Link to Item
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Li, Josephine H., Sunil Suchindran, Svati H. Shah, William E. Kraus, Geoffrey S. Ginsburg, and Deepak Voora. “SLCO1B1 genetic variants, long-term low-density lipoprotein cholesterol levels and clinical events in patients following cardiac catheterization..” Pharmacogenomics 16, no. 5 (January 2015): 449–58. https://doi.org/10.2217/pgs.15.2.Full Text
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Schick, Ursula M., Paul L. Auer, Joshua C. Bis, Honghuang Lin, Peng Wei, Nathan Pankratz, Leslie A. Lange, et al. “Association of exome sequences with plasma C-reactive protein levels in >9000 participants..” Human Molecular Genetics 24, no. 2 (January 2015): 559–71. https://doi.org/10.1093/hmg/ddu450.Full Text
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Singh, A., M. A. Babyak, D. K. Nolan, B. H. Brummett, R. Jiang, I. C. Siegler, W. E. Kraus, S. H. Shah, R. B. Williams, and E. R. Hauser. “Gene by stress genome-wide interaction analysis and path analysis identify EBF1 as a cardiovascular and metabolic risk gene.” European Journal of Human Genetics 23, no. 6 (January 1, 2015): 854–62. https://doi.org/10.1038/ejhg.2014.189.Full Text
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Lim, Elaine T., Peter Würtz, Aki S. Havulinna, Priit Palta, Taru Tukiainen, Karola Rehnström, Tõnu Esko, et al. “Distribution and medical impact of loss-of-function variants in the Finnish founder population..” Plos Genetics 10, no. 7 (July 31, 2014). https://doi.org/10.1371/journal.pgen.1004494.Full Text
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Mäkinen, Ville-Petteri, Mete Civelek, Qingying Meng, Bin Zhang, Jun Zhu, Candace Levian, Tianxiao Huan, et al. “Integrative genomics reveals novel molecular pathways and gene networks for coronary artery disease..” Plos Genet 10, no. 7 (July 2014). https://doi.org/10.1371/journal.pgen.1004502.Full Text Link to Item
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Peloso, Gina M., Paul L. Auer, Joshua C. Bis, Arend Voorman, Alanna C. Morrison, Nathan O. Stitziel, Jennifer A. Brody, et al. “Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks..” Am J Hum Genet 94, no. 2 (February 6, 2014): 223–32. https://doi.org/10.1016/j.ajhg.2014.01.009.Full Text Link to Item
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Bhattacharya, Sayanti, Christopher B. Granger, Damian Craig, Carol Haynes, James Bain, Robert D. Stevens, Elizabeth R. Hauser, et al. “Validation of the association between a branched chain amino acid metabolite profile and extremes of coronary artery disease in patients referred for cardiac catheterization..” Atherosclerosis 232, no. 1 (January 2014): 191–96. https://doi.org/10.1016/j.atherosclerosis.2013.10.036.Full Text
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Connelly, Jessica J., Olga A. Cherepanova, Jennifer F. Doss, Themistoclis Karaoli, Travis S. Lillard, Christina A. Markunas, Sarah Nelson, et al. “Epigenetic regulation of COL15A1 in smooth muscle cell replicative aging and atherosclerosis..” Human Molecular Genetics 22, no. 25 (December 2013): 5107–20. https://doi.org/10.1093/hmg/ddt365.Full Text
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Patel, Mahesh J., Bryan C. Batch, Laura P. Svetkey, James R. Bain, Christy Boling Turer, Carol Haynes, Michael J. Muehlbauer, Robert D. Stevens, Christopher B. Newgard, and Svati H. Shah. “Race and sex differences in small-molecule metabolites and metabolic hormones in overweight and obese adults..” Omics 17, no. 12 (December 2013): 627–35. https://doi.org/10.1089/omi.2013.0031.Full Text Link to Item
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Ward-Caviness, C., C. Haynes, C. Blach, E. Dowdy, S. G. Gregory, S. H. Shah, B. D. Horne, W. E. Kraus, and E. R. Hauser. “Gene-smoking interactions in multiple Rho-GTPase pathway genes in an early-onset coronary artery disease cohort.” Human Genetics 132, no. 12 (December 1, 2013): 1371–82. https://doi.org/10.1007/s00439-013-1339-7.Full Text
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Ward-Caviness, Cavin, Carol Haynes, Colette Blach, Elaine Dowdy, Simon G. Gregory, Svati H. Shah, Benjamin D. Horne, William E. Kraus, and Elizabeth R. Hauser. “Gene-smoking interactions in multiple Rho-GTPase pathway genes in an early-onset coronary artery disease cohort..” Human Genetics 132, no. 12 (December 2013): 1371–82. https://doi.org/10.1007/s00439-013-1339-7.Full Text
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Becker, R. C., D. Voora, and S. H. Shah. “Hemostasis and Thrombosis” 2 (August 29, 2013): 602–11. https://doi.org/10.1016/B978-0-12-382227-7.00052-5.Full Text
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Batch, Bryan C., Svati H. Shah, Christopher B. Newgard, Christy B. Turer, Carol Haynes, James R. Bain, Michael Muehlbauer, et al. “Branched chain amino acids are novel biomarkers for discrimination of metabolic wellness..” Metabolism: Clinical and Experimental 62, no. 7 (July 2013): 961–69. https://doi.org/10.1016/j.metabol.2013.01.007.Full Text
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Shah, Asad A., Damian M. Craig, Nicholas D. Andersen, Judson B. Williams, Syamal D. Bhattacharya, Svati H. Shah, Richard L. McCann, and G Chad Hughes. “Risk factors for 1-year mortality after thoracic endovascular aortic repair..” The Journal of Thoracic and Cardiovascular Surgery 145, no. 5 (May 2013): 1242–47. https://doi.org/10.1016/j.jtcvs.2012.05.005.Full Text
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Chan, Kenneth, Riyaz S. Patel, Paul Newcombe, Christopher P. Nelson, Atif Qasim, Stephen E. Epstein, Susan Burnett, et al. “Association between the chromosome 9p21 locus and angiographic coronary artery disease burden: a collaborative meta-analysis..” J Am Coll Cardiol 61, no. 9 (March 5, 2013): 957–70. https://doi.org/10.1016/j.jacc.2012.10.051.Full Text Link to Item
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Batch, B. C., S. H. Shah, C. B. Newgard, C. B. Turer, C. Haynes, J. R. Bain, M. Muehlbauer, et al. “Branched chain amino acids are novel biomarkers for discrimination of metabolic wellness.” Metabolism: Clinical and Experimental 62, no. 7 (2013): 961–69. https://doi.org/10.1016/j.metabol.2013.01.007.Full Text
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Brummett, Beverly H., Michael A. Babyak, Rong Jiang, Svati H. Shah, Richard C. Becker, Carol Haynes, Megan Chryst-Ladd, et al. “A functional polymorphism in the 5HTR2C gene associated with stress responses also predicts incident cardiovascular events..” Plos One 8, no. 12 (January 2013). https://doi.org/10.1371/journal.pone.0082781.Full Text Open Access Copy
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CARDIoGRAMplusC4D Consortium, Naomi J., Panos Deloukas, Stavroula Kanoni, Christina Willenborg, Martin Farrall, Themistocles L. Assimes, John R. Thompson, et al. “Large-scale association analysis identifies new risk loci for coronary artery disease..” Nature Genetics 45, no. 1 (January 2013): 25–33. https://doi.org/10.1038/ng.2480.Full Text
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Nolan, Daniel, William E. Kraus, Elizabeth Hauser, Yi-Ju Li, Dana K. Thompson, Jessica Johnson, Hsiang-Cheng Chen, et al. “Genome-wide linkage analysis of cardiovascular disease biomarkers in a large, multigenerational family..” Plos One 8, no. 8 (January 2013). https://doi.org/10.1371/journal.pone.0071779.Full Text Open Access Copy
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Shah, A. A., D. M. Craig, N. D. Andersen, J. B. Williams, S. D. Bhattacharya, S. H. Shah, R. L. McCann, and G. C. Hughes. “Risk factors for 1-year mortality after thoracic endovascular aortic repair.” Journal of Thoracic and Cardiovascular Surgery 145, no. 5 (2013): 1242–47. https://doi.org/10.1016/j.jtcvs.2012.05.005.Full Text
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Shah, Svati H., Happy Thakkar, Asad A. Shah, Nicholas D. Andersen, James Bain, Carol Haynes, Michael Muehlbauer, et al. “Metabolites Reporting on Mitochondrial Function Predict Response to Biventricular Pacing.” Circulation 126, no. 21 (November 20, 2012).Link to Item
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Shah, Svati H., Sheng Feng, Elizabeth Grass, Carol Haynes, Megan Chryst-Ladd, Damian Craig, Elizabeth R. Hauser, Christopher B. Newgard, William E. Kraus, and Simon G. Gregory. “Integration of Whole Genome Methylation with Metabolomics Identifies Novel Cardiovascular Disease Genes.” Circulation 126, no. 21 (November 20, 2012).Link to Item
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Thakkar, Happy, Jonathan P. Piccini, Albert Y. Sun, Carol Haynes, Elizabeth Grass, Kent Nilsson, Jason I. Koontz, Patrick Hranitzky, and Svati H. Shah. “Connexin-43 Gene Variants are Associated with Risk of Ventricular Arrhythmias in Patients with a Depressed Ejection Fraction.” Circulation 126, no. 21 (November 20, 2012).Link to Item
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Ward-Caviness, Cavin, Lucas Neas, Carol Haynes, Colette Blach, Elizabeth Burns, Karen LaRocque-Abramson, Elaine Dowdy, et al. “Genetic Variants in the Bone Morphogenic Protein (BMP) Family of Genes Interact with Mobile Source Air Pollution to Increase Risk of Peripheral Arterial Disease.” Circulation 126, no. 21 (November 20, 2012).Link to Item
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Levin, Pamela J., Anthony G. Visco, Svati H. Shah, Rebekah G. Fulton, and Jennifer M. Wu. “Characterizing the phenotype of advanced pelvic organ prolapse..” Female Pelvic Medicine & Reconstructive Surgery 18, no. 5 (September 2012): 299–302. https://doi.org/10.1097/SPV.0b013e31826a53de.Full Text
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Wu, Jennifer M., Anthony G. Visco, Elizabeth A. Grass, Damian M. Craig, Rebekah G. Fulton, Carol Haynes, Alison C. Weidner, and Svati H. Shah. “Matrix metalloproteinase-9 genetic polymorphisms and the risk for advanced pelvic organ prolapse..” Obstetrics and Gynecology 120, no. 3 (September 2012): 587–93. https://doi.org/10.1097/AOG.0b013e318262234b.Full Text
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Shah, Svati H., William E. Kraus, and Christopher B. Newgard. “Metabolomic profiling for the identification of novel biomarkers and mechanisms related to common cardiovascular diseases: form and function..” Circulation 126, no. 9 (August 2012): 1110–20. https://doi.org/10.1161/CIRCULATIONAHA.111.060368.Full Text
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Gurbel, Paul A., Matthew T. Roe, Joseph A. Jakubowski, Svathi Shah, David Erlinge, Shaun G. Goodman, Kurt Huber, et al. “Translational platelet research in patients with coronary artery disease: what are the major knowledge gaps?.” Thrombosis and Haemostasis 108, no. 1 (July 2012): 12–20. https://doi.org/10.1160/th12-01-0039.Full Text
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Shah, Svati H., Jie-Lena Sun, Robert D. Stevens, James R. Bain, Michael J. Muehlbauer, Karen S. Pieper, Carol Haynes, et al. “Baseline metabolomic profiles predict cardiovascular events in patients at risk for coronary artery disease..” Am Heart J 163, no. 5 (May 2012): 844-850.e1. https://doi.org/10.1016/j.ahj.2012.02.005.Full Text Link to Item
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Wu, Jennifer M., Anthony G. Visco, Elizabeth A. Grass, Damian M. Craig, Rebekah G. Fulton, Carol Haynes, Cindy L. Amundsen, and Svati H. Shah. “Comprehensive analysis of LAMC1 genetic variants in advanced pelvic organ prolapse..” American Journal of Obstetrics and Gynecology 206, no. 5 (May 2012): 447.e1-447.e6. https://doi.org/10.1016/j.ajog.2012.01.033.Full Text
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Davies, Robert W., George A. Wells, Alexandre F. R. Stewart, Jeanette Erdmann, Svati H. Shah, Jane F. Ferguson, Alistair S. Hall, et al. “A genome-wide association study for coronary artery disease identifies a novel susceptibility locus in the major histocompatibility complex..” Circulation. Cardiovascular Genetics 5, no. 2 (April 2012): 217–25. https://doi.org/10.1161/CIRCGENETICS.111.961243.Full Text
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Shah, Asad A., Damian M. Craig, Jacqueline K. Sebek, Carol Haynes, Robert C. Stevens, Michael J. Muehlbauer, Christopher B. Granger, et al. “Metabolic profiles predict adverse events after coronary artery bypass grafting..” The Journal of Thoracic and Cardiovascular Surgery 143, no. 4 (April 2012): 873–78. https://doi.org/10.1016/j.jtcvs.2011.09.070.Full Text
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Nolan, Daniel K., Beth Sutton, Carol Haynes, Jessica Johnson, Jacqueline Sebek, Elaine Dowdy, David Crosslin, et al. “Fine mapping of a linkage peak with integration of lipid traits identifies novel coronary artery disease genes on chromosome 5..” Bmc Genetics 13 (February 27, 2012). https://doi.org/10.1186/1471-2156-13-12.Full Text
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Shah, S. H., D. R. Crosslin, C. S. Haynes, S. Nelson, C. B. Turer, R. D. Stevens, M. J. Muehlbauer, et al. “Branched-chain amino acid levels are associated with improvement in insulin resistance with weight loss..” Diabetologia 55, no. 2 (February 2012): 321–30. https://doi.org/10.1007/s00125-011-2356-5.Full Text Link to Item
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Brunner, Michael P., Svati H. Shah, Damian M. Craig, Robert D. Stevens, Michael J. Muehlbauer, James R. Bain, Christopher B. Newgard, et al. “Effect of heparin administration on metabolomic profiles in samples obtained during cardiac catheterization..” Circulation. Cardiovascular Genetics 4, no. 6 (December 2011): 695–700. https://doi.org/10.1161/circgenetics.111.960575.Full Text
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Williams, Eric S., Svati H. Shah, Jonathan P. Piccini, Albert Y. Sun, Jason I. Koontz, Sana M. Al-Khatib, and Patrick M. Hranitzky. “Predictors of mortality in patients with chronic kidney disease and an implantable defibrillator: an EPGEN substudy..” Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology 13, no. 12 (December 2011): 1717–22. https://doi.org/10.1093/europace/eur253.Full Text
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Bhattacharya, Sayanti, Damian Craig, Carol Haynes, Christopher B. Granger, Robert D. Stevens, Elizabeth R. Hauser, William E. Kraus, Christopher B. Newgard, L. K. Newby, and Svati H. Shah. “Peripheral Metabolite Profiles Discriminate Coronary Artery Disease in a Sequential Cohort of Cardiac Catheterization Patients.” Circulation 124, no. 21 (November 22, 2011).Link to Item
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Lappé, Jason M., Benjamin D. Horne, Svati H. Shah, Heidi T. May, Joseph B. Muhlestein, Donald L. Lappé, Abdallah G. Kfoury, et al. “Red cell distribution width, C-reactive protein, the complete blood count, and mortality in patients with coronary disease and a normal comparison population..” Clinica Chimica Acta; International Journal of Clinical Chemistry 412, no. 23–24 (November 2011): 2094–99. https://doi.org/10.1016/j.cca.2011.07.018.Full Text
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IBC 50K CAD Consortium, Thomas J. “Large-scale gene-centric analysis identifies novel variants for coronary artery disease..” Plos Genet 7, no. 9 (September 2011). https://doi.org/10.1371/journal.pgen.1002260.Full Text Link to Item
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Voora, Deepak, John Horton, Svati H. Shah, Linda K. Shaw, and L Kristin Newby. “Polymorphisms associated with in vitro aspirin resistance are not associated with clinical outcomes in patients with coronary artery disease who report regular aspirin use..” Am Heart J 162, no. 1 (July 2011): 166-72.e1. https://doi.org/10.1016/j.ahj.2011.03.026.Full Text Link to Item
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Minear, Mollie A., David R. Crosslin, Beth S. Sutton, Jessica J. Connelly, Sarah C. Nelson, Shera Gadson-Watson, Tianyuan Wang, et al. “Polymorphic variants in tenascin-C (TNC) are associated with atherosclerosis and coronary artery disease..” Human Genetics 129, no. 6 (June 2011): 641–54. https://doi.org/10.1007/s00439-011-0959-z.Full Text
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Shah, Svati H., Laura P. Svetkey, and Christopher B. Newgard. “Branching out for detection of type 2 diabetes..” Cell Metabolism 13, no. 5 (May 2011): 491–92. https://doi.org/10.1016/j.cmet.2011.04.003.Full Text
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Laferrère, Blandine, David Reilly, Sara Arias, Nicholas Swerdlow, Prakash Gorroochurn, Baani Bawa, Mousumi Bose, et al. “Differential metabolic impact of gastric bypass surgery versus dietary intervention in obese diabetic subjects despite identical weight loss..” Sci Transl Med 3, no. 80 (April 27, 2011). https://doi.org/10.1126/scitranslmed.3002043.Full Text Link to Item
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Sun, Albert Y., Jason I. Koontz, Svati H. Shah, Jonathan P. Piccini, Kent R. Nilsson, Damian Craig, Carol Haynes, Simon G. Gregory, Patrick M. Hranitzky, and Geoffrey S. Pitt. “The S1103Y cardiac sodium channel variant is associated with implantable cardioverter-defibrillator events in blacks with heart failure and reduced ejection fraction..” Circulation. Cardiovascular Genetics 4, no. 2 (April 15, 2011): 163–68. https://doi.org/10.1161/CIRCGENETICS.110.958652.Full Text
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Plant, Sheila R., Greg P. Samsa, Svati H. Shah, and Larry B. Goldstein. “Exploration of a hypothesized independent association of a common 9p21.3 gene variant and ischemic stroke in patients with and without angiographic coronary artery disease..” Cerebrovascular Diseases (Basel, Switzerland) 31, no. 2 (January 2011): 117–22. https://doi.org/10.1159/000321510.Full Text
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Assimes, Themistocles L., Hilma Hólm, Sekar Kathiresan, Muredach P. Reilly, Gudmar Thorleifsson, Benjamin F. Voight, Jeanette Erdmann, et al. “Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies..” J Am Coll Cardiol 56, no. 19 (November 2, 2010): 1552–63. https://doi.org/10.1016/j.jacc.2010.06.022.Full Text Link to Item
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Wallentin, Lars, Stefan James, Robert F. Storey, Martin Armstrong, Bryan J. Barratt, Jay Horrow, Steen Husted, et al. “Effect of CYP2C19 and ABCB1 single nucleotide polymorphisms on outcomes of treatment with ticagrelor versus clopidogrel for acute coronary syndromes: a genetic substudy of the PLATO trial..” Lancet (London, England) 376, no. 9749 (October 2010): 1320–28. https://doi.org/10.1016/s0140-6736(10)61274-3.Full Text
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Shah, Svati H., Christopher B. Granger, Elizabeth R. Hauser, William E. Kraus, Jie-Lena Sun, Karen Pieper, Charlotte L. Nelson, et al. “Reclassification of cardiovascular risk using integrated clinical and molecular biosignatures: Design of and rationale for the Measurement to Understand the Reclassification of Disease of Cabarrus and Kannapolis (MURDOCK) Horizon 1 Cardiovascular Disease Study..” American Heart Journal 160, no. 3 (September 2010): 371-379.e2. https://doi.org/10.1016/j.ahj.2010.06.051.Full Text
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Gretarsdottir, Solveig, Annette F. Baas, Gudmar Thorleifsson, Hilma Holm, Martin den Heijer, Jean-Paul P. M. de Vries, Steef E. Kranendonk, et al. “Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm..” Nature Genetics 42, no. 8 (August 2010): 692–97. https://doi.org/10.1038/ng.622.Full Text
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Zhang, Lisheng, Jessica J. Connelly, Karsten Peppel, Leigh Brian, Svati H. Shah, Sarah Nelson, David R. Crosslin, et al. “Aging-related atherosclerosis is exacerbated by arterial expression of tumor necrosis factor receptor-1: evidence from mouse models and human association studies..” Hum Mol Genet 19, no. 14 (July 15, 2010): 2754–66. https://doi.org/10.1093/hmg/ddq172.Full Text Link to Item
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Shah, Svati H., James R. Bain, Michael J. Muehlbauer, Robert D. Stevens, David R. Crosslin, Carol Haynes, Jennifer Dungan, et al. “Association of a peripheral blood metabolic profile with coronary artery disease and risk of subsequent cardiovascular events..” Circ Cardiovasc Genet 3, no. 2 (April 2010): 207–14. https://doi.org/10.1161/CIRCGENETICS.109.852814.Full Text Open Access Copy Link to Item
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Tai, E. S., M. L. S. Tan, R. D. Stevens, Y. L. Low, M. J. Muehlbauer, D. L. M. Goh, O. R. Ilkayeva, et al. “Insulin resistance is associated with a metabolic profile of altered protein metabolism in Chinese and Asian-Indian men..” Diabetologia 53, no. 4 (April 2010): 757–67. https://doi.org/10.1007/s00125-009-1637-8.Full Text Link to Item
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Califf, Robert M., Svati H. Shah, and L Kristin Newby. “Biomarker bonanza?.” Journal of the American College of Cardiology 55, no. 12 (March 2010): 1197–99. https://doi.org/10.1016/j.jacc.2009.10.051.Full Text
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Chen, Hsiang-Cheng, Virginia Byers Kraus, Yi-Ju Li, Sarah Nelson, Carol Haynes, Jessica Johnson, Thomas Stabler, et al. “Genome-wide linkage analysis of quantitative biomarker traits of osteoarthritis in a large, multigenerational extended family..” Arthritis and Rheumatism 62, no. 3 (March 2010): 781–90. https://doi.org/10.1002/art.27288.Full Text
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Horne, Benjamin D., Elizabeth R. Hauser, Liyong Wang, Joseph B. Muhlestein, Jeffrey L. Anderson, John F. Carlquist, Svati H. Shah, and William E. Kraus. “Validation study of genetic associations with coronary artery disease on chromosome 3q13-21 and potential effect modification by smoking..” Annals of Human Genetics 73, no. Pt 6 (November 2009): 551–58. https://doi.org/10.1111/j.1469-1809.2009.00540.x.Full Text
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Koontz, Jason I., Daniel Haithcock, Valerie Cumbea, Anthony Waldron, Kristie Stricker, Amy Hughes, Kent Nilsson, et al. “Rationale and design of the Duke Electrophysiology Genetic and Genomic Studies (EPGEN) biorepository..” American Heart Journal 158, no. 5 (November 2009): 719–25. https://doi.org/10.1016/j.ahj.2009.08.011.Full Text
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Voora, Deepak, Svati H. Shah, Ivan Spasojevic, Shazia Ali, Carol R. Reed, Benjamin A. Salisbury, and Geoffrey S. Ginsburg. “The SLCO1B1*5 genetic variant is associated with statin-induced side effects..” J Am Coll Cardiol 54, no. 17 (October 20, 2009): 1609–16. https://doi.org/10.1016/j.jacc.2009.04.053.Full Text Link to Item
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Huffman, Kim M., Svati H. Shah, Robert D. Stevens, James R. Bain, Michael Muehlbauer, Cris A. Slentz, Charles J. Tanner, et al. “Relationships between circulating metabolic intermediates and insulin action in overweight to obese, inactive men and women..” Diabetes Care 32, no. 9 (September 2009): 1678–83. https://doi.org/10.2337/dc08-2075.Full Text Link to Item
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Rodgers, George P., Jamie B. Conti, Jeffrey A. Feinstein, Brian P. Griffin, Jerry D. Kennett, Svati Shah, Mary Norine Walsh, Eric S. Williams, and Jeffrey L. Williams. “ACC 2009 survey results and recommendations: Addressing the cardiology workforce crisis A report of the ACC board of trustees workforce task force..” Journal of the American College of Cardiology 54, no. 13 (September 2009): 1195–1208. https://doi.org/10.1016/j.jacc.2009.08.001.Full Text
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Shah, Svati H., and James A. de Lemos. “Biomarkers and cardiovascular disease: determining causality and quantifying contribution to risk assessment..” Jama 302, no. 1 (July 2009): 92–93. https://doi.org/10.1001/jama.2009.949.Full Text
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Newgard, C. B., J. An, J. R. Bain, M. J. Muehlbauer, R. D. Stevens, L. F. Lien, A. M. Haqq, et al. “A Branched-Chain Amino Acid-Related Metabolic Signature that Differentiates Obese and Lean Humans and Contributes to Insulin Resistance (DOI:10.1016/j.cmet.2009.02.002).” Cell Metabolism 9, no. 6 (May 14, 2009): 565–66. https://doi.org/10.1016/j.cmet.2009.05.001.Full Text
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Chan, M., R. C. Becker, S. H. Shah, and S. R. Levine. “Coagulopathy and Stroke,” April 8, 2009, 152–69. https://doi.org/10.1002/9781444308198.ch12.Full Text
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Newgard, Christopher B., Jie An, James R. Bain, Michael J. Muehlbauer, Robert D. Stevens, Lillian F. Lien, Andrea M. Haqq, et al. “A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance..” Cell Metab 9, no. 4 (April 2009): 311–26. https://doi.org/10.1016/j.cmet.2009.02.002.Full Text Link to Item
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Shah, Svati H., and Geoffrey S. Pitt. “Genetics of cardiac repolarization..” Nature Genetics 41, no. 4 (April 2009): 388–89. https://doi.org/10.1038/ng0409-388.Full Text
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Crosslin, David R., Svati H. Shah, Sarah C. Nelson, Carol S. Haynes, Jessica J. Connelly, Shera Gadson, Pascal J. Goldschmidt-Clermont, et al. “Genetic effects in the leukotriene biosynthesis pathway and association with atherosclerosis..” Human Genetics 125, no. 2 (March 2009): 217–29. https://doi.org/10.1007/s00439-008-0619-0.Full Text
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Gudbjartsson, Daniel F., Unnur S. Bjornsdottir, Eva Halapi, Anna Helgadottir, Patrick Sulem, Gudrun M. Jonsdottir, Gudmar Thorleifsson, et al. “Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction..” Nature Genetics 41, no. 3 (March 2009): 342–47. https://doi.org/10.1038/ng.323.Full Text
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Shah, Svati H., Neil J. Freedman, Lisheng Zhang, David R. Crosslin, David H. Stone, Carol Haynes, Jessica Johnson, et al. “Neuropeptide Y gene polymorphisms confer risk of early-onset atherosclerosis..” Plos Genetics 5, no. 1 (January 2, 2009). https://doi.org/10.1371/journal.pgen.1000318.Full Text Open Access Copy
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Shah, Svati H., Elizabeth R. Hauser, James R. Bain, Michael J. Muehlbauer, Carol Haynes, Robert D. Stevens, Brett R. Wenner, et al. “High heritability of metabolomic profiles in families burdened with premature cardiovascular disease..” Molecular Systems Biology 5 (January 2009). https://doi.org/10.1038/msb.2009.11.Full Text
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Voora, Deepak, Svati H. Shah, Carol R. Reed, Jun Zhai, David R. Crosslin, Chad Messer, Benjamin A. Salisbury, and Geoffrey S. Ginsburg. “Pharmacogenetic predictors of statin-mediated low-density lipoprotein cholesterol reduction and dose response..” Circulation. Cardiovascular Genetics 1, no. 2 (December 9, 2008): 100–106. https://doi.org/10.1161/CIRCGENETICS.108.795013.Full Text
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Chen, Hsiang-Cheng, Svati H. Shah, Yi-Ju Li, Thomas V. Stabler, Joanne M. Jordan, and Virginia Byers Kraus. “Inverse association of general joint hypermobility with hand and knee osteoarthritis and serum cartilage oligomeric matrix protein levels..” Arthritis and Rheumatism 58, no. 12 (December 2008): 3854–64. https://doi.org/10.1002/art.24319.Full Text
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Samad, Zainab, Tracy Y. Wang, Camille G. Frazier, Svati H. Shah, Rowena J. Dolor, and L Kristin Newby. “Closing the gap: treating hypertension in women..” Cardiology in Review 16, no. 6 (November 2008): 305–13. https://doi.org/10.1097/crd.0b013e31817f9350.Full Text
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Shah, Svati H., Elizabeth R. Hauser, David Crosslin, Liyong Wang, Carol Haynes, Jessica Connelly, Sarah Nelson, et al. “ALOX5AP variants are associated with in-stent restenosis after percutaneous coronary intervention..” Atherosclerosis 201, no. 1 (November 2008): 148–54. https://doi.org/10.1016/j.atherosclerosis.2008.01.011.Full Text Link to Item
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Chen, H. -. C., S. Shah, T. V. Stabler, Y. -. J. Li, and V. B. Kraus. “Biomarkers associated with clinical phenotypes of hand osteoarthritis in a large multigenerational family: the CARRIAGE family study..” Osteoarthritis and Cartilage 16, no. 9 (September 2008): 1054–59. https://doi.org/10.1016/j.joca.2007.12.010.Full Text
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Wang, L., E. R. Hauser, S. H. Shah, D. Seo, P. Sivashanmugam, S. T. Exum, S. G. Gregory, et al. “Polymorphisms of the tumor suppressor gene LSAMP are associated with left main coronary artery disease..” Ann Hum Genet 72, no. Pt 4 (July 2008): 443–53. https://doi.org/10.1111/j.1469-1809.2008.00433.x.Full Text Link to Item
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Sutton, Beth S., David R. Crosslin, Svati H. Shah, Sarah C. Nelson, Anthony Bassil, A Brent Hale, Carol Haynes, et al. “Comprehensive genetic analysis of the platelet activating factor acetylhydrolase (PLA2G7) gene and cardiovascular disease in case-control and family datasets..” Hum Mol Genet 17, no. 9 (May 1, 2008): 1318–28. https://doi.org/10.1093/hmg/ddn020.Full Text Link to Item
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Connelly, Jessica J., Svati H. Shah, Jennifer F. Doss, Shera Gadson, Sarah Nelson, David R. Crosslin, A Brent Hale, et al. “Genetic and functional association of FAM5C with myocardial infarction..” Bmc Medical Genetics 9 (April 22, 2008). https://doi.org/10.1186/1471-2350-9-33.Full Text
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Helgadottir, Anna, Gudmar Thorleifsson, Kristinn P. Magnusson, Solveig Grétarsdottir, Valgerdur Steinthorsdottir, Andrei Manolescu, Gregory T. Jones, et al. “The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm..” Nature Genetics 40, no. 2 (February 2008): 217–24. https://doi.org/10.1038/ng.72.Full Text
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Crowley, Anna Lisa, Manesh R. Patel, Thomas Bashore, Salvador Borges-Neto, James G. Jollis, Robert M. Judd, Raymond J. Kim, Thomas Ryan, Svati H. Shah, and Pamela S. Douglas. “Training cardiovascular specialists in imaging: a curriculum based on fundamental concepts required for multimodal imaging..” American Heart Journal 154, no. 5 (November 2007): 838–45. https://doi.org/10.1016/j.ahj.2007.07.007.Full Text
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Ginsburg, Geoffrey S., Svati H. Shah, and Jeanette J. McCarthy. “Taking cardiovascular genetic association studies to the next level..” Journal of the American College of Cardiology 50, no. 10 (September 2007): 930–32. https://doi.org/10.1016/j.jacc.2007.05.025.Full Text
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Helgadottir, A., G. Thorleifsson, A. Manolescu, S. Gretarsdottir, T. Blondal, A. Jonasdottir, A. Sigurdsson, et al. “A common variant on chromosome 9p21 affects the risk of myocardial infarction.” Obstetrical and Gynecological Survey 62, no. 9 (September 1, 2007): 585–87. https://doi.org/10.1097/01.ogx.0000279313.65556.85.Full Text
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Helgadottir, Anna, Gudmar Thorleifsson, Andrei Manolescu, Solveig Gretarsdottir, Thorarinn Blondal, Aslaug Jonasdottir, Adalbjorg Jonasdottir, et al. “A common variant on chromosome 9p21 affects the risk of myocardial infarction..” Science (New York, N.Y.) 316, no. 5830 (June 2007): 1491–93. https://doi.org/10.1126/science.1142842.Full Text
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Shah, Svati H. “Gene polymorphisms and susceptibility to coronary artery disease..” Pediatric Blood & Cancer 48, no. 7 (June 2007): 738–41. https://doi.org/10.1002/pbc.21110.Full Text
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Wang, Liyong, Elizabeth R. Hauser, Svati H. Shah, Margaret A. Pericak-Vance, Carol Haynes, David Crosslin, Marco Harris, et al. “Peakwide mapping on chromosome 3q13 identifies the kalirin gene as a novel candidate gene for coronary artery disease..” American Journal of Human Genetics 80, no. 4 (April 2007): 650–63. https://doi.org/10.1086/512981.Full Text
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Shah, S. H., W. E. Kraus, D. C. Crossman, C. B. Granger, J. L. Haines, C. J. Jones, V. Mooser, et al. “Serum lipids in the GENECARD study of coronary artery disease identify quantitative trait loci and phenotypic subsets on chromosomes 3q and 5q..” Annals of Human Genetics 70, no. Pt 6 (November 2006): 738–48. https://doi.org/10.1111/j.1469-1809.2006.00288.x.Full Text
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Connelly, J. J., T. Wang, J. E. Cox, C. Haynes, L. Wang, S. H. Shah, D. R. Crosslin, et al. “GATA2 is associated with familial early-onset coronary artery disease..” Plos Genetics 2, no. 8 (August 25, 2006). https://doi.org/10.1371/journal.pgen.0020139.Full Text
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Connelly, Jessica J., Tianyuan Wang, Julie E. Cox, Carol Haynes, Liyong Wang, Svati H. Shah, David R. Crosslin, et al. “GATA2 is associated with familial early-onset coronary artery disease..” Plos Genetics 2, no. 8 (August 2006). https://doi.org/10.1371/journal.pgen.0020139.Full Text
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Shah, S. H., D. S. Liebeskind, J. L. Saver, S. Starkman, F. Vinuela, G. Duckwiler, R. Jahan, et al. “Influence of gender on outcomes after intra-arterial thrombolysis for acute ischemic stroke.” Neurology 66, no. 11 (2006): 1745–46. https://doi.org/10.1212/01.wnl.0000218208.31305.84.Full Text
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Shah, Svati H., Michael A. Schmidt, Hao Mei, William K. Scott, Elizabeth R. Hauser, and Silke Schmidt. “Searching for epistatic interactions in nuclear families using conditional linkage analysis..” Bmc Genetics 6 Suppl 1 (December 30, 2005). https://doi.org/10.1186/1471-2156-6-S1-S148.Full Text
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Frazier, Camille G., Svati H. Shah, Paul W. Armstrong, Manjushri V. Bhapkar, Darren K. McGuire, Zygmunt Sadowski, Arni Kristinsson, et al. “Prevalence and management of hypertension in acute coronary syndrome patients varies by sex: observations from the Sibrafiban versus aspirin to Yield Maximum Protection from ischemic Heart events postacute cOroNary sYndromes (SYMPHONY) randomized clinical trials..” American Heart Journal 150, no. 6 (December 2005): 1260–67. https://doi.org/10.1016/j.ahj.2005.08.004.Full Text
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Shah, S., M. Patel, A. Goyal, A. Amos, R. Baeza, A. Halabi, G. Lam, R. G. Mitchell, G. Oliveira, and A. M. Valente. “Highlights from the American Heart Association Annual Scientific Sessions 2004: November 7-10, 2004.” American Heart Journal 149, no. 2 (January 1, 2005): 240–53. https://doi.org/10.1016/j.ahj.2004.12.001.Full Text
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Parsons, Elizabeth, L Kristin Newby, Manjushri V. Bhapkar, Karen P. Alexander, Harvey D. White, Svati H. Shah, Cheryl D. Bushnell, Robert M. Califf, and Robert M. Symphony and 2nd Symphony Investigators. “Postmenopausal hormone use in women with acute coronary syndromes..” Journal of Women’S Health (2002) 13, no. 8 (October 2004): 863–71. https://doi.org/10.1089/jwh.2004.13.863.Full Text
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Hauser, Elizabeth R., David C. Crossman, Christopher B. Granger, Jonathan L. Haines, Christopher J. H. Jones, Vincent Mooser, Brendan McAdam, et al. “A genomewide scan for early-onset coronary artery disease in 438 families: the GENECARD Study..” American Journal of Human Genetics 75, no. 3 (September 2004): 436–47. https://doi.org/10.1086/423900.Full Text
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Shah, Svati H., Jean-Pierre Dery, Michael C. Fischi, John F. Heitner, Geoffrey A. Kunz, Trip J. Meine, Manesh R. Patel, Anne Marie Valente, Richard E. Waters, and Jonathan Yager. “Highlights from the American College of Cardiology Annual Scientific Sessions 2004: March 9-12, 2004..” American Heart Journal 148, no. 2 (August 2004). https://doi.org/10.1016/j.ahj.2004.05.028.Full Text
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Shah, Svati H., and L Kristin Newby. “C-reactive protein: a novel marker of cardiovascular risk..” Cardiology in Review 11, no. 4 (July 2003): 169–79. https://doi.org/10.1097/01.crd.0000077906.74217.6e.Full Text
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Shah, S. H., K. P. Alexander, and E. D. Peterson. “PCI in women.” Cardiology Review 20, no. 3 (March 1, 2003): 24–29.
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Shah, Svati H., Michael H. Sketch, and James E. Tcheng. “Acute myocardial infarction in a young male while playing paintball..” The Journal of Invasive Cardiology 14, no. 11 (November 2002): 713–15.
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Other Articles
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Kertai, Miklos D., Yen-Wei Li, Yi-Ju Li, Svati H. Shah, William E. Kraus, Manuel L. Fontes, Mark Stafford-Smith, et al. “G protein-coupled receptor kinase 5 gene polymorphisms are associated with postoperative atrial fibrillation after coronary artery bypass grafting in patients receiving β-blockers..” Circulation. Cardiovascular Genetics, October 2014. https://doi.org/10.1161/CIRCGENETICS.113.000451.Full Text
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Conference Papers
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Karhausen, Jörn A., Wenjing Qi, Alan M. Smeltz, Yi-Ju Li, Svati H. Shah, William E. Kraus, Joseph P. Mathew, Mihai V. Podgoreanu, Miklos D. Kertai, and Miklos D. Duke Perioperative Genetics Safety Outcomes (PEGASUS) Investigative Team. “Genome-Wide Association Study Links Receptor Tyrosine Kinase Inhibitor Sprouty 2 to Thrombocytopenia after Coronary Artery Bypass Surgery..” In Thrombosis and Haemostasis, 118:1572–85, 2018. https://doi.org/10.1055/s-0038-1667199.Full Text
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Denus, S. de, J. L. Rouleau, D. L. Mann, G. S. Huggins, T. P. Cappola, S. H. Shah, J. Keleti, et al. “A pharmacogenetic investigation of intravenous furosemide in decompensated heart failure: a meta-analysis of three clinical trials..” In Pharmacogenomics J, 17:192–200, 2017. https://doi.org/10.1038/tpj.2016.4.Full Text Link to Item
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Kelly, J. P., W. Hunter, R. W. McGarrah, D. Craig, C. Haynes, E. J. Velazquez, G. M. Felker, et al. “Novel Protein Glycan Inflammatory Biomarkers Predict Adverse Events in Heart Failure with Preserved Ejection Fraction.” In Journal of Cardiac Failure, 21:S89–S89, 2015. https://doi.org/10.1016/j.cardfail.2015.06.266.Full Text
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Aras, Mandar A., Damian M. Craig, Carol Haynes, James R. Bain, Michael J. Muehlbauer, Robert D. Stevens, Olga Ilkayeva, et al. “Peripheral Metabolite Profiles Predict Cardiomyopathy in a Cohort of Cardiac Catheterization Patients.” In Circulation, Vol. 128. LIPPINCOTT WILLIAMS & WILKINS, 2013.Link to Item
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Dokun, Ayotunde O., Mitsuharu Okutsu, Damian Craig, Svati H. Shah, W Schuyler Jones, Douglas A. Marchuk, R John Lye, and Brian H. Annex. “ADAM12 Modifies Severity of Peripheral Arterial Disease; Evidence From Preclinical and Human Studies.” In Circulation, Vol. 128. LIPPINCOTT WILLIAMS & WILKINS, 2013.Link to Item
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Li, Josephine H., Sunil Suchindran, Svati H. Shah, William E. Kraus, Geoffrey S. Ginsburg, and Deepak Voora. “Effect of SLCO1B1*5 on Low-Density Lipoprotein Cholesterol Levels and Long-Term Clinical Events in Patients During Statin Therapy Following Cardiac Catheterization.” In Circulation, Vol. 128. LIPPINCOTT WILLIAMS & WILKINS, 2013.Link to Item
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McGarrah, Robert W., Damian M. Craig, Carol Haynes, Z Elaine Dowdy, Svati H. Shah, and William E. Kraus. “High-density Lipoprotein Particle Concentration Has a Stronger Inverse Association With Cardiovascular Events Than High-density Lipoprotein Cholesterol in a Coronary Catheterization Population.” In Circulation, Vol. 128. LIPPINCOTT WILLIAMS & WILKINS, 2013.Link to Item
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Shah, Svati H., Lydia Kwee, Nathan Stitziel, Elizabeth R. Hauser, Carol Haynes, Sekar Kathiresan, Simon G. Gregory, and William E. Kraus. “Rare Variants Identified With Whole Exome Chip Genotyping Are Associated With Insulin Resistance and Glycemic Control.” In Circulation, Vol. 128. LIPPINCOTT WILLIAMS & WILKINS, 2013.Link to Item
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Shah, Svati H., William E. Kraus, Olga Ilkaveva, Robert Stevens, Carol Haynes, Gregory D. Lewis, Christopher B. Newgard, and Robert E. Gerszten. “Metabolomic Profiling in a Human Model of Myocardial Infarction Identifies Novel Early Biomarkers of Cellular Damage.” In Circulation, Vol. 128. LIPPINCOTT WILLIAMS & WILKINS, 2013.Link to Item
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Chan, K., R. S. Patel, P. Newcombe, C. P. Nelson, A. Qasim, S. E. Epstein, S. Burnett, et al. “126 CHROMOSOME 9P21 LOCUS AND ANGIOGRAPHIC CORONARY ARTERY DISEASE BURDEN: A COLLABORATIVE META-ANALYSIS.” In Heart, 99:A75.1-A75. BMJ, 2013. https://doi.org/10.1136/heartjnl-2013-304019.126.Full Text
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Kraus, William E., Mark P. Donahue, Svati H. Shah, David J. Whellan, Anne Hellkamp, Christopher M. O’Connor, and G. M. Felker. “Association of Small Molecule Metabolic Intermediates that Predict Cardiovascular Mortality with Peak VO2 in a Heart Failure Population.” In Circulation, Vol. 127. LIPPINCOTT WILLIAMS & WILKINS, 2013.Link to Item
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Kraus, William E., Sheng Feng, Elizabeth R. Hauser, Simon G. Gregory, Carol Haynes, Z. E. Dowdy, Damian M. Craig, and Svati H. Shah. “Association of Gene Expression Signatures with Small Molecule Metabolic Intermediates that Predict Cardiovascular Mortality in CATHGEN.” In Circulation, Vol. 127. LIPPINCOTT WILLIAMS & WILKINS, 2013.Link to Item
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Ward-Caviness, Cavin, Lucas Neas, Carol Haynes, Colette Blachi, Wayne Cascio, Robert Devlin, David Diaz-Sanchez, et al. “Mobile Source Air Pollution is Associated with the Plasma Concentration of Multiple Acylcarnitines in a Large Cardiovascular Cohort.” In Circulation, Vol. 127. LIPPINCOTT WILLIAMS & WILKINS, 2013.Link to Item
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Shah, Asad A., Damian M. Craig, Carol Haynes, Jacqueline K. Sebek, Elizabeth Grass, Karen Abramson, Peter K. Smith, et al. “Genome-Wide Association Identifies Genetic Variants Associated With Vein Graft Stenosis After Coronary Artery Bypass Grafting.” In Circulation, Vol. 124. LIPPINCOTT WILLIAMS & WILKINS, 2011.Link to Item
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Shah, Asad A., Damian M. Craig, Judson B. Williams, Syamal D. Bhattacharya, Nicholas D. Andersen, Svati H. Shah, Richard L. McCann, and G Chad Hughes. “PS24. Risk Factors for Non-Procedure Related Mortality One Year after Thoracic Endovascular Aortic Repair.” In Journal of Vascular Surgery, 53:36S-36S. Elsevier BV, 2011. https://doi.org/10.1016/j.jvs.2011.03.077.Full Text
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