Sven Eric Jordt

Conference American Journal of Respiratory and Critical Care Medicine · May 1, 2025 AbstractRATIONALE: The tobacco industry is known for constantly probing FDA's regulatory limits. In 2023, an e-cigarette product was introduced that, instead of nicotine, delivers a nicotine analogue, 6-m ... Full text Cite

Proteomics, Redox Proteomics, and Metabolomics Profiling of Phosgene-induced Lung Injury in a Murine Model

Conference American Journal of Respiratory and Critical Care Medicine · May 1, 2025 AbstractBackground: Phosgene is an industrial chemical known to cause severe lung injury following acute exposure. Understanding the molecular mechanisms underlying phosgene-induced acute lung injury (ALI ... Full text Cite

An Acute Porcine Phosgene Pulmonary Injury Model: Potential Biomarkers and Drug Targets

Conference American Journal of Respiratory and Critical Care Medicine · May 1, 2025 AbstractBackground: Phosgene is one of the highly produced industrial gases and is an essential intermediate in polymer, pharmaceutical, and metallurgy synthesis. However, phosgene is highly toxic when in ... Full text Cite

Proinflammatory Pulmonary Effects of SARS-CoV-2 Main Protease in Mice and Human Bronchial Epithelial Cells

Conference American Journal of Respiratory and Critical Care Medicine · May 1, 2025 AbstractRationale: The SARS-CoV-2 main protease (Mpro, also known as 3CLpro or Nsp5), is a critical enzyme in the viral replication process, cleaving viral nonstructural polypeptides into individual funct ... Full text Cite

Pharmacological Modulations of MRGPRX4 by Sensory Cooling Agents (Abstract ID: 161612)

Conference The Journal of Pharmacology and Experimental Therapeutics · March 2025 Full text Cite

Recapitulation of human pathophysiology and identification of forensic biomarkers in a translational model of chlorine inhalation injury

Conference Mechanisms of lung injury and repair · September 14, 2024 Full text Cite

Synthetic cooling agents and nicotine analogs in new tobacco products: tobacco industry strategies to bypass regulation

Conference Tobacco, smoking control and health education · September 14, 2024 Full text Cite

Vagus nerve stimulation rescues persistent pain following orthopedic surgery in adult mice.

Conference Pain · August 1, 2024 Postoperative pain is a major clinical problem imposing a significant burden on patients and society. In a survey 2 years after orthopedic surgery, 57% of patients reported persisting postoperative pain. However, only limited progress has been made in the ... Full text Link to item Cite

An Electronic Cigarette Pod System Delivering 6-methyl Nicotine, A Synthetic Nicotine Analog, Marketed in the United States as "PMTA Exempt"

Conference AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE · May 1, 2024 Link to item Cite

Soluble Epoxide Hydrolase Inhibitors and ACE Inhibitors Ameliorate Phosgene Inhalation Injuries

Conference AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE · May 1, 2023 Link to item Cite

High Toxicity of Cinnamon-flavored Electronic Cigarette Liquids: A Lesson Not Learned

Conference AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE · May 1, 2023 Link to item Cite

Synthetic Cooling Agents in California-Marketed "Non-menthol" Cigarette Brands Introduced After the State's Menthol Ban

Conference AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE · May 1, 2023 Link to item Cite

Effect Of Comt Genetic Background And Stress On Pain Following Tibial Fracture

Conference JOURNAL OF PAIN · April 2023 Link to item Cite

Biomarkers and Drugs Targets for Phosgene Induced Pulmonary Inhalation Injuries

Conference AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE · May 1, 2022 Link to item Cite

Synthetic Cooling Agents in US-Marketed E-cigarette Refill Liquids and Disposable E-cigarettes: Chemical Analysis and Risk Assessment

Conference AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE · May 1, 2022 Link to item Cite

Chemical Adducts of Flavor Aldehydes Formed in E-Cigarette Liquids Are Cytotoxic and Inhibit Mitochondrial Function in Respiratory Epithelial Cells

Conference CHEMICAL SENSES · September 27, 2021 Link to item Cite

Cellular Respiratory Toxicity of Novel Flavor-Solvent Adducts in Electronic Cigarettes

Conference AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE · May 1, 2021 Link to item Cite

Chlorinated Tyrosine Adducts as Biomarkers of Chlorine Gas Exposure in a Swine Model

Conference AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE · May 1, 2021 Link to item Cite

The Airway Sensory Nerve Transcriptome: Evidence for Neuropathic Injury Following Lipopolysaccharide Induced Lung Inflammation

Conference AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE · May 1, 2021 Link to item Cite

Chlorinated Tyrosine Adducts as Biomarkers of Chlorine Gas Exposure in a Swine Model

Conference TP62. TP062 TERRORISM AND INHALATIONAL DISASTERS: WORLD TRADE CENTER AND BEYOND · May 2021 Full text Cite

Cellular Respiratory Toxicity of Novel Flavor-Solvent Adducts in Electronic Cigarettes

Conference TP109. TP109 COPD AND E-CIGARETTES: PRE-CLINICAL MODELS AND MECHANISMS · May 2021 Full text Cite

The Airway Sensory Nerve Transcriptome: Evidence for Neuropathic Injury Following Lipopolysaccharide Induced Lung Inflammation

Conference TP4. TP004 ARDS, SEPSIS, AND TRANSPLANTATION MECHANISTIC STUDIES · May 2021 Full text Cite

Chemical Adducts of Flavor Aldehydes Formed in E-Cigarette Liquids Are Cytotoxic and Inhibit Mitochondrial Function in Respiratory Epithelial Cells

Conference CHEMICAL SENSES · January 1, 2021 Link to item Cite

Late Breaking Abstract - Differences in flavorant levels and synthetic coolant use between USA, EU and Canadian Juul products

Conference Tobacco, smoking control and health educ. · September 7, 2020 Full text Cite

Flavor-solvent reaction products in electronic cigarette liquids activate respiratory irritant receptors and elicit cytotoxic metabolic responses in airway epithelial cell

Conference Tobacco, smoking control and health educ. · September 7, 2020 Full text Cite

Exposure biomarkers in a pig model of chlorine inhalation injury

Conference Occupational and environmental health · September 7, 2020 Full text Cite

Late Breaking Abstract - The airway sensory nerve transcriptome: evidence for neuropathic injury following lipopolysaccharide induced lung inflammation

Conference Molecular pathology and funct. genomics · September 7, 2020 Full text Cite

The Airway Sensory Nerve Transcriptome: Evidence for Neuropathic Injury Following Lipopolysaccharide Induced Lung Inflammation

Conference AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE · 2020 Link to item Cite

Biomarkers of Chlorine Gas Exposure in a Swine Model

Conference AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE · 2020 Link to item Cite

Activation of Respiratory Irritant Receptors by Pulegone, A Toxic Flavor Chemical in Mint- or Menthol-Flavored Electronic Cigarettes

Conference AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE · 2020 Link to item Cite

The sensory irritant receptor TRPA1 is essential for airway inflammation in the LPS mouse model of acute lung injury

Conference Airway pharmacology and treatment · September 28, 2019 Full text Cite

TRPV4 Inhibitor Improves Pulmonary Function and Oxygen Saturation in a Pig Translational Model of Chlorine Gas-Induced Acute Lung Injury

Conference AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE · January 1, 2019 Link to item Cite

Flavor-Solvent Adducts In Electronic Cigarette Liquids Are Modulators of Respiratory Irritant Receptors with Distinct Toxicological Effects on Lung Epithelial Cells

Conference AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE · January 1, 2019 Link to item Cite

Propylene Glycol and Glycerin in E-Cigarettes Elicit Respiratory Irritation Responses and Modulate Human Sensory Irritant Receptor Function

Conference AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE · January 1, 2019 Link to item Cite

Chemical Adducts of Flavorants in E-cigarette Liquid Solvents Act As Modulators of Respiratory Irritant Receptors

Conference CHEMICAL SENSES · September 1, 2018 Link to item Cite

TRP Ion Channels as Key Targets of Tobacco and Electronic Cigarette Irritants and Flavor Additives

Conference CHEMICAL SENSES · May 1, 2018 Link to item Cite

Chemical Adducts Of Flavorants With E-Cigarette Liquid Solvents Act As Modulators Of Respiratory Irritant Receptors

Conference AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE · January 1, 2017 Link to item Cite

The anti-inflammatory effects of eucalyptol in a mouse model of LPS-induced pulmonary inflammation are mediated by TRPM8

Conference 5.1 Airway Pharmacology and Treatment · September 2016 Full text Cite

TRPM8 Mediates the Anti-inflammatory Effects of Eucalyptol in a Mouse Model of LPS-Induced Pulmonary Inflammation

Conference FASEB JOURNAL · April 1, 2016 Link to item Cite

Menthol Attenuates Chemosensory Irritation and Elevates blood Cotinine in Cigarette Smoke Exposed Mice

Conference CHEMICAL SENSES · September 1, 2015 Link to item Cite

Nicotine addiction: molecular basis of behaviors at the complex interface between reward, food intake and taste

Conference CHEMICAL SENSES · September 1, 2015 Link to item Cite

Acetaminophen Potentiates Respiratory Responses To Environmental Tobacco Smoke

Conference AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE · January 1, 2015 Link to item Cite

Activation Of Chemosensory Receptors And Respiratory Irritation Responses By Electronic Cigarette Flavorants And Vapors

Conference AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE · January 1, 2015 Link to item Cite

TRPA1 Controls Inflammation and Pruritogen Responses in Allergic Contact Dermatitis

Conference JOURNAL OF GENERAL PHYSIOLOGY · August 1, 2014 Link to item Cite

TRPA1 CONTROLS INFLAMMATION AND PRURITOGEN RESPONSES IN ALLERGIC CONTACT DERMATITIS

Conference ACTA DERMATO-VENEREOLOGICA · January 1, 2013 Link to item Cite

Menthol Blocks Respiratory Irritation Responses To Cigarette Smoke Via Trpm8 Receptor Pathways

Conference AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE · January 1, 2013 Link to item Cite

Sensory TRP Channels in Airway Chemosensation and Inflammation.

Conference JOURNAL OF GENERAL PHYSIOLOGY · July 1, 2012 Link to item Cite

Screening Spider Toxin Libraries for TRP Channel Inhibitors

Conference BIOPHYSICAL JOURNAL · February 2, 2011 Link to item Cite

Decreased Ovalbumin-induced Airway Inflammation in Mice Deficient in the Sensory Neuronal Ion Channel TRPA1

Conference FASEB JOURNAL · April 1, 2009 Link to item Cite

Decreased Ovalbumin-Induced Airway Inflammation in Mice Deficient in the Sensory Neuronal Ion Channel TRPA1

Conference AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE · January 1, 2009 Link to item Cite

Molecular and Cellular Mechanisms of Trigeminal Chemosensation

Conference CHEMICAL SENSES · October 1, 2008 Link to item Cite

Paclitaxel induces alterations in InsP(3) mediated calcium signaling via calpain mediated NCS-1 degradation in neuronal cells.

Conference BIOPHYSICAL JOURNAL · January 1, 2007 Link to item Cite

Mustard oils and cannabinoids excite sensory nerve fibers via the trp channel TRPA1

Conference JOURNAL OF NEUROCHEMISTRY · August 1, 2005 Link to item Cite

Molecular determinants of ligand interaction with the capsaicin receptor

Conference Journal of Neurochemistry · June 2003 Birds are indifferent to the pain‐producing effects of capsaicin. However, avian primary sensory neurons exhibit heat‐evoked membrane currents resembling those carried by mammalian capsaicin receptors. We aimed to identify an avian capsaicin recept ... Full text Cite

Acid potentiation of the capsaicin receptor determined by a key extracellular site

Conference Journal of Neurochemistry · June 2003 The capsaicin receptor, VR1, is a sensory neuron‐specific ion channel that serves as a detector of pain‐producing chemical and physical stimuli. The response of VR1 to capsaicin or heat is dynamically potentiated by extracellular protons within a p ... Full text Cite