Tatjana Abaffy

Our studies focus on the mechanisms of chemo-sensation, especially the function of olfactory receptors and their interaction with the ligand. We are also interested in the olfactory receptor's function outside the olfactory system, and in particular, their role in various human pathologies. The key questions are which agonists/metabolites activate these ectopic receptors, what types of non-neuronal responses are evoked by their activation, and how we can design novel agonists and antagonists. Future projects will also aim at a better understanding of olfactory receptor regulation by sex-steroid hormones.