Scholars@Duke

• Background
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  Education, Training, & Certifications

  • Ph.D., University of Auckland (New Zealand) 2000
• Research
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  Selected Grants

  • Biogenesis of olfactory G protein-coupled receptors awarded by National Institutes of Health 2017 - 2022
  • Peripheral Odor Coding in Mammals awarded by National Institutes of Health 2015 - 2021
  • Olfactory moding in mammals awarded by University of Pennsylvania 2015 - 2020
• Publications & Artistic Works
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  Selected Publications

  • Academic Articles

    • Abaffy, Tatjana, et al. “A Testosterone Metabolite 19-Hydroxyandrostenedione Induces Neuroendocrine Trans-Differentiation of Prostate Cancer Cells via an Ectopic Olfactory Receptor.” Front Oncol, vol. 8, 2018, p. 162. Pubmed, doi:10.3389/fonc.2018.00162.
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    • Bavan, Selvan, et al. “Discovery of novel ligands for mouse olfactory receptor MOR42-3 using an in silico screening approach and in vitro validation.” Plos One, vol. 9, no. 3, 2014, p. e92064. Pubmed, doi:10.1371/journal.pone.0092064.
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    • Jiang, Ruifen, et al. “A non-invasive method for in vivo skin volatile compounds sampling.” Anal Chim Acta, vol. 804, Dec. 2013, pp. 111–19. Pubmed, doi:10.1016/j.aca.2013.09.056.
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    • Abaffy, T., et al. “Comparative analysis of volatile metabolomics signals from melanoma and benign skin: a pilot study.” Metabolomics, vol. 9, no. 5, 2013, pp. 998–1008. Pubmed, doi:10.1007/s11306-013-0523-z.
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    • Abaffy, Tatjana, and Anthony R. Defazio. “The location of olfactory receptors within olfactory epithelium is independent of odorant volatility and solubility.” Bmc Res Notes, vol. 4, May 2011, p. 137. Pubmed, doi:10.1186/1756-0500-4-137.
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    • Defazio, R. Anthony, et al. “A protocol for characterizing the impact of collateral flow after distal middle cerebral artery occlusion.” Transl Stroke Res, vol. 2, no. 1, Mar. 2011, pp. 112–27. Pubmed, doi:10.1007/s12975-010-0044-2.
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    • Abaffy, Tatjana, et al. “A case report - Volatile metabolomic signature of malignant melanoma using matching skin as a control.” J Cancer Sci Ther, vol. 3, no. 6, 2011, pp. 140–44. Pubmed, doi:10.4172/1948-5956.1000076.
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    • Abaffy, Tatjana, et al. “Differential volatile signatures from skin, naevi and melanoma: a novel approach to detect a pathological process.” Plos One, vol. 5, no. 11, Nov. 2010, p. e13813. Pubmed, doi:10.1371/journal.pone.0013813.
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    • Menashe, Idan, et al. “Genetic elucidation of human hyperosmia to isovaleric acid.” Plos Biol, vol. 5, no. 11, Oct. 2007, p. e284. Pubmed, doi:10.1371/journal.pbio.0050284.
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    • Abaffy, Tatjana, et al. “The molecular basis for ligand specificity in a mouse olfactory receptor: a network of functionally important residues.” J Biol Chem, vol. 282, no. 2, Jan. 2007, pp. 1216–24. Pubmed, doi:10.1074/jbc.M609355200.
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    • Abaffy, Tatjana, et al. “Functional analysis of a mammalian odorant receptor subfamily.” J Neurochem, vol. 97, no. 5, June 2006, pp. 1506–18. Pubmed, doi:10.1111/j.1471-4159.2006.03859.x.
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    • Abaffy, Tatjana, and Garth J. S. Cooper. “GSK3 involvement in amylin signaling in isolated rat soleus muscle.” Peptides, vol. 25, no. 12, Dec. 2004, pp. 2119–25. Pubmed, doi:10.1016/j.peptides.2004.08.016.
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    • Abaffy, T., et al. “Adenylyl cyclase expression and modulation of cAMP in rat taste cells.” American Journal of Physiology  Cell Physiology, vol. 284, no. 6 53-6, June 2003.
    • Topic, E., et al. “Troponin T and serum enzymes in monitoring open heart surgery.” Acta Clinica Croatica, vol. 33, no. 1–2, Jan. 1994, pp. 77–85.
• Teaching & Mentoring
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  Recent Courses

  • MGM 593: Research Independent Study 2020
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  Advising & Mentoring

  Available to mentor:

  • PhD
  • Undergraduate

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