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Thomas Myron Coffman

James R. Clapp Distinguished Professor of Medicine, in the School of Medicine
Medicine, Nephrology
Duke Box 103015, Durham, NC 27710
Room 2018/MSBR2, 106 Research Drive, Durham, NC 27710

Scholarly Works - Conferences


Systems Genetics Identifies a Podocyte Activity Network in Diabetic Nephropathy

Conference JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY · October 2025 Link to item Cite

Role for IL-11 Signalling in Diabetic Nephropathy

Conference JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY · October 2025 Link to item Cite

Beneficial Effects of Tumor Necrosis Factor α Blockade in a Mouse Model of Diabetic Nephropathy

Conference JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY · October 2021 Link to item Cite

Understanding Genetic Mechanisms of Diabetic Nephropathy at the Single-Cell Level

Conference JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY · October 2021 Link to item Cite

Aldosterone-Induced Vascular Remodeling and Endothelial Dysfunction Require Functional Angiotensin Type 1a Receptors.

Conference Hypertension · May 2016 We investigated the role of angiotensin type 1a receptors (AGTR1a) in vascular injury induced by aldosterone activation of mineralocorticoid receptors in Agtr1a(-/-) and wild-type (WT) mice infused with aldosterone for 14 days while receiving 1% NaCl in dr ... Full text Link to item Cite

AT1 ANGIOTENSIN RECEPTORS IN THE KIDNEY: A KEY TO BLOOD PRESSURE CONTROL

Conference JOURNAL OF PHYSIOLOGICAL SCIENCES · January 1, 2009 Link to item Cite

Slit2 impairs monocyte chemotaxis

Conference PEDIATRIC NEPHROLOGY · September 2008 Link to item Cite

UCP-2 limits the development of angiotensin II-induced renal sclerosis

Conference NEPHROLOGY DIALYSIS TRANSPLANTATION · July 1, 2006 Link to item Cite

Hypertension in Cyp2j5 null mice is estrogen responsive.

Conference JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY · November 1, 2003 Link to item Cite

Angiotensin II promotes cytoskeletal rearrangements in lymphocytes

Conference JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY · November 1, 2003 Link to item Cite

Exacerbation of diabetic kidney disease in ApoE deficient mice.

Conference JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY · November 1, 2003 Link to item Cite

Strain-specific differences in streptozotocin-induced diabetes in the mouse.

Conference JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY · November 1, 2003 Link to item Cite

A role for thromboxane A2 in cellular immunity and allograft rejection.

Conference JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY · September 2002 Link to item Cite

The role of CCR2 in T cell responses.

Conference JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY · September 2002 Link to item Cite

Estimation of albuminuria by the use of albumin-to-creatinine ratios in the mouse.

Conference JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY · September 2002 Link to item Cite

The EGF receptor tyrosine kinase promotes hypertension and kidney injury during no inhibition.

Conference JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY · September 2002 Link to item Cite

Regulation of blood pressure by the angiotensin converting enzyme homologue ACE2.

Conference JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY · September 2002 Link to item Cite

Cytochrome P450 Cyp2j5 regulates blood pressure and estrogen metabolism in female mice.

Conference JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY · September 2002 Link to item Cite

Genetic variants that increase AT1 receptor expression preferentially raise blood pressure in females.

Conference JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY · September 1, 2002 Link to item Cite

The type I (AT(1)) angiotensin receptor regulates cytokine production during lymphocyte activation.

Conference JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY · September 1, 2002 Link to item Cite

Neuroendocrine effects of dehydration in mice lacking the angiotensin AT1a receptor.

Conference Hypertension · January 1999 Angiotensin (Ang) type 1a (AT1a) receptors are critical in the control of blood pressure and water balance. Experiments were performed to determine the influence of dehydration on brain Ang receptors and plasma vasopressin (VP) in mice lacking this recepto ... Full text Link to item Cite

Expression of the C-C chemokine receptor 2 (CCR2) on donor tissue promotes allograft rejection.

Conference JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY · September 1997 Link to item Cite

Rejection of kidneys lacking normal class I and II MHC expression.

Conference JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY · September 1997 Link to item Cite

Modulation of urinary concentrating mechanisms by the EP3 receptor for prostaglandin (PG) E-2.

Conference JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY · September 1997 Link to item Cite

A severe kidney phenotype in AT(1A) receptor-deficient mice.

Conference JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY · September 1997 Link to item Cite

Renin response and tubular function in angiotensin II type 1A receptor knockout mice.

Conference JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY · September 1997 Link to item Cite

Altered vasopressin axis in the AT-1a knockout mouse.

Conference FASEB JOURNAL · February 28, 1997 Link to item Cite

A novel approach for transient expression of foreign proteins in renal endothelium.

Conference JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY · September 1996 Link to item Cite

Inducible nitric oxide synthase (iNOS) is not required for efficient allograft rejection.

Conference JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY · September 1996 Link to item Cite

Release of ecosanoids and modulation of cyclooxygenase-2 in a xenograft model.

Conference JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY · September 1996 Link to item Cite

Thromboxane receptors (TXR) are expressed and mediate apoptosis in EL4 thymoma cells.

Conference JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY · September 1996 Link to item Cite

AT1B receptors regulate blood pressure in mice lacking AT1A receptors for angiotensin (Ang) II.

Conference JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY · September 1996 Link to item Cite

Thromboxane (TX) stimulates plasminogen activator inhibitor-1 (PAI-1) production by mesangial cells.

Conference JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY · September 1, 1996 Link to item Cite

NORMAL RENAL GROWTH AND DEVELOPMENT IN MICE LACKING TYPE 1A (AT(1A)) RECEPTORS FOR ANGIOTENSIN-II

Conference JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY · September 1995 Link to item Cite

ACE-INHIBITION REDUCES BLOOD-PRESSURE IN MICE LACKING TYPE 1A (AT(1A)) RECEPTORS FOR ANGIOTENSIN-II

Conference JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY · September 1995 Link to item Cite

ISOLATION OF CD8(+)ALPHA/BETA-TCR(-) CELLS FROM LONG-TERM SURVIVING MOUSE KIDNEY ALLOGRAFTS

Conference JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY · September 1995 Link to item Cite

THROMBOXANE RECEPTOR (TXR) EXPRESSION AND SIGNALING IN THE THYMUS

Conference JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY · September 1995 Link to item Cite

DISTRIBUTION OF THROMBOXANE RECEPTORS (TXR) LN THE MOUSE KIDNEY

Conference JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY · September 1995 Link to item Cite

CD4+ T-CELL INFILTRATES ARE ABSENT IN CLASS-II DEFICIENT MOUSE RENAL-ALLOGRAFTS

Conference JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY · September 1994 Link to item Cite

ISOLATION OF A GENOMIC CLONE THAT ENCODES A KIDNEY THROMBOXANE-A(2) (TXA(2)) RECEPTOR

Conference JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY · September 1, 1994 Link to item Cite

LEUKOTRIENE PRODUCTION IS STIMULATED IN MURINE LUPUS NEPHRITIS

Conference KIDNEY INTERNATIONAL · January 1, 1990 Link to item Cite