https://orcid.org/0000-0001-9689-2047
Current Duke Appointments & Affiliations
Professor of Urology
·
2023 - Present
Urology,
Clinical Science Departments
Professor of Pediatrics
·
2025 - Present
Pediatrics,
Clinical Science Departments
Recent Scholarly Works
Acute perioperative alterations in metabolism: A pilot study using mass spectrometry-based metabolomics.
Journal article Surgery · April 2025 OBJECTIVE: To characterize early physiologic stresses imposed by surgery by applying metabolomic analyses to deeply phenotype pre- and postoperative plasma and urine of patients undergoing elective surgical procedures. BACKGROUND: Patients experience perio ... Full text Link to item CiteMale Akita diabetic mice develop underactive bladder independent of NLRP3 that can be prevented with blood glucose control.
Journal article Continence (Amst) · December 2024 AIM: Diabetic bladder dysfunction (DBD) is the most common diabetic complication. Patients present with overactive symptoms, underactive symptoms, or both. While strict glucose control may be expected to reverse DBD, prior studies have not been supportive. ... Full text Open Access Link to item CiteStrict glucose control and elimination of NLRP3-induced inflammation prevents diabetic bladder dysfunction in the female Akita mouse model.
Journal article Neurourol Urodyn · November 2024 PURPOSE: Diabetic bladder dysfunction (DBD) is the most common diabetic complication. Logically, regulation of blood glucose should reverse dysfunction, but the Epidemiology of Diabetes Interventions and Complications study found strict control ineffective ... Full text Open Access Link to item CiteRecent Grants
Inflammation and neuropathy drive sex-specific diabetic bladder dysfunction in Akita mice
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2026 - 2031Advanced Immunobiology Traning Program for Surgeons
Inst. Training Prgm or CMEMentor · Awarded by National Institute of Allergy and Infectious Diseases · 2019 - 2029Duke KURe Program
Inst. Training Prgm or CMEMentor · Awarded by National Institute of Diabetes and Digestive and Kidney Diseases · 2013 - 2028View All Grants
Education
University of Illinois, College of Medicine ·
2000
M.D.
University of Illinois, Urbana-Champaign ·
1998
Ph.D.
Cornell University ·
1991
A.B.