Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Pediatric Urology Fellow, Surgery/Urology, Johns Hopkins University School of Medicine 2006 - 2008
  • Urology Resident, Surgery/Urology, University of Arizona College of Medicine 2002 - 2006
  • General Surgery Resident, Surgery, University of Arizona College of Medicine 2000 - 2002
  • M.D., University of Illinois College of Medicine 2000
  • Ph.D., University of Illinois -- Urbana-Champaign 1998
  • A.B., Cornell University 1991
• 

  Duke Appointment History

  • Instructor, Temporary in the Department of Surgery, Surgery, Urology, Surgery 2015
• Research
• 

  Selected Grants

  • BOTOX in the Treatment of Urinary Incontinence Due to Neurognic Detrusor Overactivity in Patients 5 to 17 Years of Age awarded by Allergan, Inc. 2017 - 2022
  • LT Botox for UI awarded by Allergan, Inc. 2017 - 2019
  • Inflammasomes Mediate Inflammation in Bladder Outlet Obstruction awarded by National Institutes of Health 2015 - 2019
  • Diabetes and Diabetic Uropathy awarded by National Institutes of Health 2017 - 2018
  • Duke KURe Program awarded by National Institutes of Health 2013 - 2018
  • Purves/Inouye AUA Resident Award awarded by American Urological Association Foundation 2016 - 2017
• Publications & Artistic Works
• 

  Selected Publications

  • Journal Articles

    • Tejwani, R, Jiang, R, Wolf, S, Adkins, DW, Young, BJ, Alkazemi, M, Wiener, JS, Pomann, G-M, Purves, JT, and Routh, JC. "Contemporary Demographic, Treatment, and Geographic Distribution Patterns for Disorders of Sex Development." Clinical pediatrics 57, no. 3 (March 2018): 311-318.  Full Text
    • Jiang, R, Wolf, S, Alkazemi, MH, Pomann, G-M, Purves, JT, Wiener, JS, and Routh, JC. "The evaluation of three comorbidity indices in predicting postoperative complications and readmissions in pediatric urology." Journal of pediatric urology (February 26, 2018).  Full Text
    • Inouye, BM, Hughes, FM, Sexton, SJ, and Purves, JT. "The Emerging Role of Inflammasomes as Central Mediators in Inflammatory Bladder Pathology." Current Urology 11, no. 2 (February 1, 2018): 57-72. (Review)  Full Text
    • Lütolf, R, Hughes, FM, Inouye, BM, Jin, H, McMains, JC, Pak, ES, Hannan, JL, and Purves, JT. "NLRP3/IL-1β mediates denervation during bladder outlet obstruction in rats." Neurourology and urodynamics (October 6, 2017).  Full Text
    • Hughes, FM, Sexton, SJ, Jin, H, Govada, V, and Purves, JT. "Bladder fibrosis during outlet obstruction is triggered through the NLRP3 inflammasome and the production of IL-1β." American journal of physiology. Renal physiology 313, no. 3 (September 2017): F603-F610.  Full Text
    • Tejwani, R, Young, BJ, Wang, H-HS, Wolf, S, Purves, JT, Wiener, JS, and Routh, JC. "Open versus minimally invasive surgical approaches in pediatric urology: Trends in utilization and complications." Journal of pediatric urology 13, no. 3 (June 2017): 283.e1-283.e9.  Full Text
    • Purves, JT, Spruill, L, Rovner, E, Borisko, E, McCants, A, Mugo, E, Wingard, A, Trusk, TC, Bacro, T, and Hughes, FM. "A three dimensional nerve map of human bladder trigone." Neurourology and urodynamics 36, no. 4 (April 2017): 1015-1019.  Full Text
    • Purves, JT, and Hughes, FM. "Inflammasomes in the urinary tract: a disease-based review." American journal of physiology. Renal physiology 311, no. 4 (October 2016): F653-F662. (Review)  Full Text
    • Young, BJ, Tejwani, R, Wang, H-HS, Wolf, S, Purves, JT, Wiener, JS, and Routh, JC. "Is the Economic Impact and Utilization of Imaging Studies for Pediatric Urolithiasis Across the United States Increasing?." Urology 94 (August 2016): 208-213.  Full Text
    • Hughes, FM, Hill, HM, Wood, CM, Edmondson, AT, Dumas, A, Foo, W-C, Oelsen, JM, Rac, G, and Purves, JT. "The NLRP3 Inflammasome Mediates Inflammation Produced by Bladder Outlet Obstruction." The Journal of urology 195, no. 5 (May 2016): 1598-1605.  Full Text
    • Hughes, FM, Turner, DP, and Todd Purves, J. "The potential repertoire of the innate immune system in the bladder: expression of pattern recognition receptors in the rat bladder and a rat urothelial cell line (MYP3 cells)." International urology and nephrology 47, no. 12 (December 2015): 1953-1964.  Full Text

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