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Michael Anthony Moody

Professor of Pediatrics
Pediatrics, Infectious Diseases
Box 106016 DUMC, Durham, NC 27710
Rm 2139, 27 Alexandria Way, Room 2135 / DUMC Box 106016, Durham, NC 27703

Overview


Tony Moody, MD is a Professor in the Department of Pediatrics, Division of Infectious Diseases and Professor in the Department of Integrative Immunobiology at Duke University Medical Center. Research in the Moody lab is focused on understanding the B cell responses during infection, vaccination, and disease. The lab has become a resource for human phenotyping, flow characterization, staining and analysis at the Duke Human Vaccine Institute (DHVI). The Moody lab is currently funded to study influenza, syphilis, HIV-1, and emerging infectious diseases.

Dr. Moody is the director of the Duke CIVICs Vaccine Center (DCVC) at (DHVI) and co-director of the Centers for Research of Emerging Infectious Disease Coordinating Center (CREID-CC). Dr. Moody is mPI of a U01 program to develop a syphilis vaccine; this program is a collaboration with mPI Dr. Justin Radolf at the University of Connecticut. Dr. Moody is also the director of the DHVI Accessioning Unit, a biorepository that provides support for work occurring at DHVI and with its many collaborators around the world by providing processing, shipping, and inventory support for a wide array of projects.

Dr. Moody and his team are involved in many networks studying vaccine response including the Collaborative Influenza Vaccine Innovation Centers (CIVICs) and the COVID-19 Prevention Network (CoVPN).

Current Appointments & Affiliations


Professor of Pediatrics · 2020 - Present Pediatrics, Infectious Diseases, Pediatrics
Professor in Immunology · 2020 - Present Integrative Immunobiology, Basic Science Departments
Member of the Duke Human Vaccine Institute · 2005 - Present Duke Human Vaccine Institute, Institutes and Centers

In the News


Published March 25, 2025
Duke Honors 31 New Distinguished Professors
Published April 27, 2023
Why You Should Get Tested for Syphilis
Published August 31, 2020
Better, Faster Research on Emerging Infectious Diseases

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Recent Publications


Fluorescence-barcoded cell lines stably expressing membrane-anchored influenza neuraminidases.

Journal Article Vaccine · May 22, 2025 The discovery of broadly protective antibodies to the influenza virus neuraminidase (NA) has raised interest in NA as a vaccine target. However, recombinant, solubilized tetrameric NA ectodomains are often challenging to express and isolate, hindering the ... Full text Link to item Cite

Disease diagnostics using machine learning of B cell and T cell receptor sequences.

Journal Article Science · February 21, 2025 Clinical diagnosis typically incorporates physical examination, patient history, various laboratory tests, and imaging studies but makes limited use of the human immune system's own record of antigen exposures encoded by receptors on B cells and T cells. W ... Full text Link to item Cite
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Recent Grants


Stimulating Access to Research in Residency (StARR) - NIAID

Inst. Training Prgm or CMEPreceptor · Awarded by National Institutes of Health · 2018 - 2029

A Global Syphilis Vaccine Targeting Outer Membrane Proteins of Treponema pallidum

ResearchPrincipal Investigator · Awarded by National Institute of Allergy and Infectious Diseases · 2024 - 2029

Structure-function analysis of infection- and vaccine-induced B-cell repertoires

ResearchPrincipal Investigator · Awarded by Boston Children's Hospital · 2023 - 2028

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Education, Training & Certifications


Duke University · 1999 M.D.