Overview
Program Start Year: 2021
Rotating Student
Rotating Student
Recent Publications
Structure-guided design and synthesis of C22- and C32-modified FK520 analogs with enhanced activity against human pathogenic fungi.
Journal Article Proc Natl Acad Sci U S A · January 7, 2025 Invasive fungal infections are a leading cause of death worldwide. Translating molecular insights into clinical benefits is challenging because fungal pathogens and their hosts share similar eukaryotic physiology. Consequently, current antifungal treatment ... Full text Link to item CiteRestriction of innate Tγδ17 cell plasticity by an AP-1 regulatory axis.
Preprint · October 18, 2024 Full text Link to item CiteIntegrin α3 promotes TH17 cell polarization and extravasation during autoimmune neuroinflammation.
Journal Article Sci Immunol · October 20, 2023 Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS) caused by CNS-infiltrating leukocytes, including TH17 cells that are critical mediators of disease pathogenesis. Although targeting leukocyte trafficking is effective in t ... Full text Link to item CiteRecent Grants
Regulatory mechanisms governing Th17 cell effector identity and plasticity
ResearchResearch Assistant · Awarded by National Institutes of Health · 2025 - 2030Molecular basis of gd T lineage specification - Core B: Genomics Core
ResearchResearch Assistant · Awarded by Fox Chase Cancer Center · 2025 - 2030Project 2: The role of TCR, ligand, and signal strength in human ¿¿ T cell development
ResearchResearch Assistant · Awarded by Fox Chase Cancer Center · 2025 - 2030View All Grants