Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Anesthesiology Residency, Anesthesiology, Technical University of Munich (Germany) 2011 - 2014
  • M.D., Charite Universitatsmedizin Berlin (Germany) 2004
• 

  Duke Appointment History

  • Medical Instructor in the Department of Anesthesiology, Anesthesiology, Neuroanesthesia, Anesthesiology 2015 - 2017
• Research
• 

  Selected Grants

  • High resolution awake cortical recordings to analyze the role of spreading depolarizations during dynamic stroke evolution awarded by National Institutes of Health 2019 - 2021
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Ma, Shuang, Dongmei Chu, Litao Li, Jennifer A. Creed, Yu-Mi Ryang, Huaxin Sheng, Wei Yang, David S. Warner, Dennis A. Turner, and Ulrike Hoffmann. “Argon Inhalation for 24 Hours After Onset of Permanent Focal Cerebral Ischemia in Rats Provides Neuroprotection and Improves Neurologic Outcome..” Crit Care Med 47, no. 8 (August 2019): e693–99. https://doi.org/10.1097/CCM.0000000000003809.
       Full Text  Link to Item
    • Lan, Bangxin, Wei Liu, Ya-Chao Wang, Junhui Shi, Yang Li, Song Xu, Huaxin Sheng, et al. “High-speed widefield photoacoustic microscopy of small-animal hemodynamics..” Biomed Opt Express 9, no. 10 (October 1, 2018): 4689–4701. https://doi.org/10.1364/BOE.9.004689.
       Full Text  Link to Item
    • Oka, Fumiaki, Ulrike Hoffmann, Jeong Hyun Lee, Hwa Kyoung Shin, David Y. Chung, Izumi Yuzawa, Shih-Pin Chen, et al. “Requisite ischemia for spreading depolarization occurrence after subarachnoid hemorrhage in rodents..” J Cereb Blood Flow Metab 37, no. 5 (May 2017): 1829–40. https://doi.org/10.1177/0271678X16659303.
       Full Text  Link to Item
    • Hoffmann, Ulrike, Huaxin Sheng, Cenk Ayata, and David S. Warner. “Anesthesia in Experimental Stroke Research..” Transl Stroke Res 7, no. 5 (October 2016): 358–67. https://doi.org/10.1007/s12975-016-0491-5.
       Full Text  Link to Item
    • Sasaki, Toshihiro, Ulrike Hoffmann, Motomu Kobayashi, Huaxin Sheng, Abdelkader Ennaceur, Frederick W. Lombard, and David S. Warner. “Long-Term Cognitive Deficits After Subarachnoid Hemorrhage in Rats..” Neurocrit Care 25, no. 2 (October 2016): 293–305. https://doi.org/10.1007/s12028-016-0250-1.
       Full Text  Link to Item
    • Hoffmann, Ulrike, Martina Grosse-Sundrup, Katharina Eikermann-Haerter, Sebastina Zaremba, Cenk Ayata, Ben Zhang, Da Ma, Lyle Isaacs, and Matthias Eikermann. “Calabadion: A new agent to reverse the effects of benzylisoquinoline and steroidal neuromuscular-blocking agents..” Anesthesiology 119, no. 2 (August 2013): 317–25. https://doi.org/10.1097/ALN.0b013e3182910213.
       Full Text  Link to Item
    • Hoffmann, Ulrike, Inna Sukhotinsky, Katharina Eikermann-Haerter, and Cenk Ayata. “Glucose modulation of spreading depression susceptibility..” J Cereb Blood Flow Metab 33, no. 2 (February 2013): 191–95. https://doi.org/10.1038/jcbfm.2012.132.
       Full Text  Link to Item
    • Hoffmann, Ulrike, and Cenk Ayata. “Neurovascular coupling during spreading depolarizations..” Acta Neurochir Suppl 115 (2013): 161–65. https://doi.org/10.1007/978-3-7091-1192-5_31.
       Full Text  Link to Item
    • Hoffmann, Ulrike, Inna Sukhotinsky, Yahya Burak Atalay, Katharina Eikermann-Haerter, and Cenk Ayata. “Increased glucose availability does not restore prolonged spreading depression durations in hypotensive rats without brain injury..” Exp Neurol 238, no. 2 (December 2012): 130–32. https://doi.org/10.1016/j.expneurol.2012.08.013.
       Full Text  Link to Item
    • Ma, Da, Ben Zhang, Ulrike Hoffmann, Martina Grosse Sundrup, Matthias Eikermann, and Lyle Isaacs. “Acyclic cucurbit[n]uril-type molecular containers bind neuromuscular blocking agents in vitro and reverse neuromuscular block in vivo..” Angew Chem Int Ed Engl 51, no. 45 (November 5, 2012): 11358–62. https://doi.org/10.1002/anie.201206031.
       Full Text  Link to Item
    • Eikermann, Matthias, Martina Grosse-Sundrup, Sebastian Zaremba, Mark E. Henry, Edward A. Bittner, Ulrike Hoffmann, and Nancy L. Chamberlin. “Ketamine activates breathing and abolishes the coupling between loss of consciousness and upper airway dilator muscle dysfunction..” Anesthesiology 116, no. 1 (January 2012): 35–46. https://doi.org/10.1097/ALN.0b013e31823d010a.
       Full Text  Link to Item
    • Eikermann, Matthias, Ramalingam Vetrivelan, Martina Grosse-Sundrup, Mark E. Henry, Ulrike Hoffmann, Shigefumi Yokota, Clifford B. Saper, and Nancy L. Chamberlin. “The ventrolateral preoptic nucleus is not required for isoflurane general anesthesia..” Brain Res 1426 (December 2, 2011): 30–37. https://doi.org/10.1016/j.brainres.2011.10.018.
       Full Text  Link to Item
    • Hoffmann, Ulrike, Jeong Hyun Lee, Tao Qin, Katharina Eikermann-Haerter, and Cenk Ayata. “Gabapentin reduces infarct volume but does not suppress peri-infarct depolarizations..” J Cereb Blood Flow Metab 31, no. 7 (July 2011): 1578–82. https://doi.org/10.1038/jcbfm.2011.50.
       Full Text  Link to Item
    • Eikermann-Haerter, Katharina, Izumi Yuzawa, Tao Qin, Yumei Wang, Kwangyeol Baek, Young Ro Kim, Ulrike Hoffmann, et al. “Enhanced subcortical spreading depression in familial hemiplegic migraine type 1 mutant mice..” J Neurosci 31, no. 15 (April 13, 2011): 5755–63. https://doi.org/10.1523/JNEUROSCI.5346-10.2011.
       Full Text  Link to Item
    • Hoffmann, Ulrike, Ergin Dileköz, Chiho Kudo, and Cenk Ayata. “Oxcarbazepine does not suppress cortical spreading depression..” Cephalalgia 31, no. 5 (April 2011): 537–42. https://doi.org/10.1177/0333102410388433.
       Full Text  Link to Item
    • Khuman, Jugta, William P. Meehan, Xiaoxia Zhu, Jianhua Qiu, Ulrike Hoffmann, Jimmy Zhang, Eric Giovannone, Eng H. Lo, and Michael J. Whalen. “Tumor necrosis factor alpha and Fas receptor contribute to cognitive deficits independent of cell death after concussive traumatic brain injury in mice..” J Cereb Blood Flow Metab 31, no. 2 (February 2011): 778–89. https://doi.org/10.1038/jcbfm.2010.172.
       Full Text  Link to Item
    • Hoffmann, Ulrike, Ergin Dileköz, Chiho Kudo, and Cenk Ayata. “Gabapentin suppresses cortical spreading depression susceptibility..” J Cereb Blood Flow Metab 30, no. 9 (September 2010): 1588–92. https://doi.org/10.1038/jcbfm.2010.92.
       Full Text  Link to Item
    • Hoffmann, Ulrike, Jörn Pomper, Johannes Graulich, Melanie Zeller, Sebastian Schuchmann, Siegrun Gabriel, Rolf F. Maier, and Uwe Heinemann. “Changes of neuronal activity in areas CA1 and CA3 during anoxia and normoxic or hyperoxic reoxygenation in juvenile rat organotypic hippocampal slice cultures..” Brain Res 1069, no. 1 (January 19, 2006): 207–15. https://doi.org/10.1016/j.brainres.2005.11.025.
       Full Text  Link to Item
    • Pomper, Jörn K., Stephan Haack, Gabor C. Petzold, Katharina Buchheim, Siegrun Gabriel, Ulrike Hoffmann, and Uwe Heinemann. “Repetitive spreading depression-like events result in cell damage in juvenile hippocampal slice cultures maintained in normoxia..” J Neurophysiol 95, no. 1 (January 2006): 355–68. https://doi.org/10.1152/jn.00186.2005.
       Full Text  Link to Item
    • Pomper, Jörn K., Ulrike Hoffmann, Richard Kovács, Siegrun Gabriel, and Uwe Heinemann. “Hyperoxia is not an essential condition for status epilepticus induced cell death in organotypic hippocampal slice cultures..” Epilepsy Res 59, no. 1 (March 2004): 61–65. https://doi.org/10.1016/j.eplepsyres.2004.03.002.
       Full Text  Link to Item
    • Weber, Astrid, Rolf F. Maier, Ulrike Hoffmann, Martin Grips, Marc Hoppenz, Ayse G. Aktas, Uwe Heinemann, Michael Obladen, and Sebastian Schuchmann. “Erythropoietin improves synaptic transmission during and following ischemia in rat hippocampal slice cultures..” Brain Res 958, no. 2 (December 27, 2002): 305–11. https://doi.org/10.1016/s0006-8993(02)03604-1.
       Full Text  Link to Item
    • Graulich, Johannes, Ulrike Hoffmann, Rolf F. Maier, Karsten Ruscher, Jörn K. Pomper, Hae-Kyung Ko, Siegrun Gabriel, Michael Obladen, and Uwe Heinemann. “Acute neuronal injury after hypoxia is influenced by the reoxygenation mode in juvenile hippocampal slice cultures..” Brain Res Dev Brain Res 137, no. 1 (July 30, 2002): 35–42. https://doi.org/10.1016/s0165-3806(02)00365-6.
       Full Text  Link to Item
    • Pomper, J. K., J. Graulich, R. Kovacs, U. Hoffmann, S. Gabriel, and U. Heinemann. “High oxygen tension leads to acute cell death in organotypic hippocampal slice cultures..” Brain Res Dev Brain Res 126, no. 1 (January 31, 2001): 109–16. https://doi.org/10.1016/s0165-3806(00)00132-2.
       Full Text  Link to Item
    • Busch, T., S. Wolf, A. Sommerer, U. Hoffmann, H. Lohbrunner, K. J. Falke, and U. Kaisers. “Partial liquid ventilation (PLV) compared to inhaled nitric oxide (INO) in an animal model of acute lung injury (ALI): Effects on pulmonary gas exchange.” Critical Care Medicine 27, no. 12 SUPPL. (December 1, 1999).
    • Sommerer, A., T. Busch, U. Hoffmann, S. Wolf, K. Kämpf, K. Falke, and U. Kaisers. “Low doses of almitrine compared to inhaled nitric oxide (iNO) in an animal model of acute lung injury (ALI): Effects on pulmonary gas exchange.” Critical Care Medicine 27, no. 1 SUPPL. (December 1, 1999).

Some information on this profile has been compiled automatically from Duke databases and external sources. (Our About page explains how this works.) If you see a problem with the information, please write to Scholars@Duke and let us know. We will reply promptly.