Uptal Dinesh Patel | Scholars@Duke

Uptal Dinesh Patel
Adjunct Professor in the Department of Medicine

Uptal Patel, MD is an Adjunct Professor interested in population health with a broad range of clinical and research experience. As an adult and pediatric nephrologist with training in health services and epidemiology, his work seeks to improve population health for patients with kidney diseases through improvements in prevention, diagnosis and treatment.

Prior efforts focused on four inter-related areas that are essential to improving kidney health: i) reducing the progression of chronic kidney disease by improving its detection and management, particularly by leveraging technology to facilitate engagement and self-management; ii) elucidating the inter-relationships between kidney disease and cardiovascular disease, which together amplify the risk of death; iii) improving the evidence in nephrology through comparative effectiveness research, including clinical trials, observational studies, and meta-analyses; and iv) promoting more optimal clinical health policy for all patients with kidney disease. These inter-disciplinary projects have been funded by a variety of public and private sources including the Robert Wood Johnson Foundation, Veterans Affairs, National Institutes of Health, Agency for Healthcare Research & Quality, Food and Drug Administration, Centers for Medicare & Medicaid Services, Renal Physicians Association, and the American Society of Nephrology.

Current efforts seek to advance novel therapies for kidney diseases through early clinical development that he leads at AstraZeneca.

Current Appointments & Affiliations

Adjunct Professor in the Department of Medicine, Medicine, Nephrology, Medicine 2016
Member in the Duke Clinical Research Institute, Duke Clinical Research Institute, Institutes and Centers 2005
Affiliate, Duke Global Health Institute, Duke Global Health Institute, University Institutes and Centers 2015

Contact Information

1 Medimmune Way, Gaithersburg, MD 20878-2204
Duke Box 3646, 2400 Pratt Street, Durham, NC 27705
uptal.patel@duke.edu (650) 339-8061
Clinical Profile
DOCK Clinical & Translational Core

Background
Education, Training, & Certifications
- Fellow in Nephrology, Medicine, University of Michigan, Ann Arbor 2002 - 2003
- Fellow in Pediatric Nephrology, Pediatrics, University of Michigan, Ann Arbor 2001 - 2002
- Medicine/Pediatric Resident, Medicine/Pediatrics, University of Michigan, Ann Arbor 1997 - 2001
- M.D., University of California San Francisco, School of Medicine 1997
Duke Appointment History
- Associate Professor in Pediatrics, Pediatrics, Nephrology, Pediatrics 2012 - 2019
- Adjunct Associate Professor in the Department of Medicine, Medicine, Nephrology, Medicine 2016
- Associate Professor of Medicine, Medicine, Nephrology, Medicine 2014 - 2016
- Associate Professor of Medicine, Medicine, Nephrology, Medicine 2012 - 2014
- Assistant Professor of Medicine, Medicine, Nephrology, Medicine 2005 - 2011
- Assistant Professor of Pediatrics, Pediatrics, Nephrology, Pediatrics 2005 - 2011
- Instructor, Temporary in the Department of Medicine, Medicine, Nephrology, Medicine 2005
Expertise
Subject Headings
Global Scholarship
- Research
  - United Republic of Tanzania (Country)
Research
Selected Grants
- Putting Patients at the Center of Kidney Care Transitions awarded by Patient Centered Outcomes Research Institute 2016 - 2022
- Integrated Population Program for Diabetic Kidney Disease awarded by National Institutes of Health 2014 - 2018
- Health Literacy and Social Determinants among Individuals with Chronic Kidney Disease in an Underserved Community awarded by American Kidney Fund 2015 - 2017
- Dietary Acid Load, Subclinical Acidosis and Outcomes in Chronic Kidney Disease awarded by National Institutes of Health 2012 - 2017
- PTN Task Order #7: Lisinopril awarded by National Institutes of Health 2011 - 2015
- Barriers to Optimal Cardiovascular Medication Use in Diabetes and Renal Disease awarded by National Institutes of Health 2006 - 2011
- EPC_TO#3_WA#7_Anemia Management in Renal Disease Populations - Part 2 awarded by Agency for Healthcare Research and Quality 2010
- EPC _TO #1_WA #3_Anemia Management in Renal Disease Populations - (Part 1) awarded by Agency for Healthcare Research and Quality 2010
External Relationships
- AstraZeneca
- Gilead Sciences, Inc.
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Abedini, Amin, Yuan O. Zhu, Shatakshee Chatterjee, Gabor Halasz, Kishor Devalaraja-Narashimha, Rojesh Shrestha, Michael S. Balzer, et al. “Urinary Single-Cell Profiling Captures the Cellular Diversity of the Kidney.” J Am Soc Nephrol 32, no. 3 (March 2021): 614–27. https://doi.org/10.1681/ASN.2020050757.
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  - Baker, Matthew, Yashaar Chaichian, Mark Genovese, Vimal Derebail, Panduranga Rao, Winn Chatham, Michael Bubb, et al. “Phase II, randomised, double-blind, multicentre study evaluating the safety and efficacy of filgotinib and lanraplenib in patients with lupus membranous nephropathy.” Rmd Open 6, no. 3 (December 2020). https://doi.org/10.1136/rmdopen-2020-001490.
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  - Kobe, Elizabeth A., Clarissa J. Diamantidis, Hayden B. Bosworth, Clemontina A. Davenport, Megan Oakes, Anastasia-Stefania Alexopoulos, Jane Pendergast, Uptal D. Patel, and Matthew J. Crowley. “Racial Differences in the Effectiveness of a Multifactorial Telehealth Intervention to Slow Diabetic Kidney Disease.” Med Care 58, no. 11 (November 2020): 968–73. https://doi.org/10.1097/MLR.0000000000001387.
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  - Levin, Adeera, Rajiv Agarwal, William G. Herrington, Hiddo L. Heerspink, Johannes F. E. Mann, Shahnaz Shahinfar, Katherine R. Tuttle, et al. “International consensus definitions of clinical trial outcomes for kidney failure: 2020.” Kidney Int 98, no. 4 (October 2020): 849–59. https://doi.org/10.1016/j.kint.2020.07.013.
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  - Nelson, Cara H., Kim Etchevers, Saili Yi, David Breckenridge, Mischa Hepner, Uptal Patel, John Ling, and Anita Mathias. “Pharmacokinetics, Safety, and Tolerability of Selonsertib, an Apoptosis Signal-Regulating Kinase 1 (ASK1) Inhibitor, Following First-in-Human Single and Multiple Ascending Doses in Healthy Subjects.” Clin Pharmacokinet 59, no. 9 (September 2020): 1109–17. https://doi.org/10.1007/s40262-020-00878-y.
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  - Townsend, Raymond R., Paolo Guarnieri, Christos Argyropoulos, Shira Blady, Carine M. Boustany-Kari, Kishor Devalaraja-Narashimha, Lori Morton, et al. “Rationale and design of the Transformative Research in Diabetic Nephropathy (TRIDENT) Study.” Kidney Int 97, no. 1 (January 2020): 10–13. https://doi.org/10.1016/j.kint.2019.09.020.
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  - Chertow, Glenn M., Pablo E. Pergola, Fang Chen, Brian J. Kirby, John S. Sundy, Uptal D. Patel, and Uptal D. GS-US-223-1015 Investigators. “Effects of Selonsertib in Patients with Diabetic Kidney Disease.” J Am Soc Nephrol 30, no. 10 (October 2019): 1980–90. https://doi.org/10.1681/ASN.2018121231.
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  - Telford, Onala, Clarissa J. Diamantidis, Hayden B. Bosworth, Uptal D. Patel, Clemontina A. Davenport, Megan M. Oakes, and Matthew J. Crowley. “The relationship between Pittsburgh Sleep Quality Index subscales and diabetes control.” Chronic Illn 15, no. 3 (September 2019): 210–19. https://doi.org/10.1177/1742395318759587.
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  - Lewinski, Allison A., Uptal D. Patel, Clarissa J. Diamantidis, Megan Oakes, Khaula Baloch, Matthew J. Crowley, Jonathan Wilson, et al. “Addressing Diabetes and Poorly Controlled Hypertension: Pragmatic mHealth Self-Management Intervention.” J Med Internet Res 21, no. 4 (April 9, 2019): e12541. https://doi.org/10.2196/12541.
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  - Green, J. A., P. L. Ephraim, F. F. Hill-Briggs, T. Browne, T. S. Strigo, C. L. Hauer, R. A. Stametz, et al. “Putting patients at the center of kidney care transitions: PREPARE NOW, a cluster randomized controlled trial.” Contemp Clin Trials 73 (October 2018): 98–110. https://doi.org/10.1016/j.cct.2018.09.004.
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  - Tomilo, Mark, Heather Ascani, Barbara Mirel, Maria Chiara Magnone, Carol Moreno Quinn, Anil Karihaloo, Kevin Duffin, Uptal D. Patel, and Matthias Kretzler. “Renal Pre-Competitive Consortium (RPC2): discovering therapeutic targets together.” Drug Discov Today 23, no. 10 (October 2018): 1695–99. https://doi.org/10.1016/j.drudis.2018.05.021.
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  - Diamantidis, Clarissa J., Hayden B. Bosworth, Megan M. Oakes, Clemontina A. Davenport, Jane F. Pendergast, Sejal Patel, Jivan Moaddeb, et al. “Simultaneous Risk Factor Control Using Telehealth to slOw Progression of Diabetic Kidney Disease (STOP-DKD) study: Protocol and baseline characteristics of a randomized controlled trial.” Contemp Clin Trials 69 (June 2018): 28–39. https://doi.org/10.1016/j.cct.2018.04.003.
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  - Zullig, Leah L., Clarissa J. Diamantidis, Hayden B. Bosworth, Manjushri V. Bhapkar, Huiman Barnhart, Megan M. Oakes, Jane F. Pendergast, Julie J. Miller, and Uptal D. Patel. “Racial differences in nocturnal dipping status in diabetic kidney disease: Results from the STOP-DKD (Simultaneous Risk Factor Control Using Telehealth to Slow Progression of Diabetic Kidney Disease) study.” J Clin Hypertens (Greenwich) 19, no. 12 (December 2017): 1327–35. https://doi.org/10.1111/jch.13088.
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  - Galson, Sophie W., Catherine A. Staton, Francis Karia, Kajiru Kilonzo, Joseph Lunyera, Uptal D. Patel, Julian T. Hertz, and John W. Stanifer. “Epidemiology of hypertension in Northern Tanzania: a community-based mixed-methods study.” Bmj Open 7, no. 11 (November 9, 2017): e018829. https://doi.org/10.1136/bmjopen-2017-018829.
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  - Rosner, Mitchell H., Susie Q. Lew, Paul Conway, Jennifer Ehrlich, Robert Jarrin, Uptal D. Patel, Karen Rheuban, et al. “Perspectives from the Kidney Health Initiative on Advancing Technologies to Facilitate Remote Monitoring of Patient Self-Care in RRT.” Clin J Am Soc Nephrol 12, no. 11 (November 7, 2017): 1900–1909. https://doi.org/10.2215/CJN.12781216.
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  - Samad, Zainab, Joseph A. Sivak, Matthew Phelan, Phillip J. Schulte, Uptal Patel, and Eric J. Velazquez. “Prevalence and Outcomes of Left-Sided Valvular Heart Disease Associated With Chronic Kidney Disease.” J Am Heart Assoc 6, no. 10 (October 11, 2017). https://doi.org/10.1161/JAHA.117.006044.
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  - Nadkarni, Girish N., Steven G. Coca, Allison Meisner, Shanti Patel, Kathleen F. Kerr, Uptal D. Patel, Jay L. Koyner, et al. “Urinalysis findings and urinary kidney injury biomarker concentrations.” Bmc Nephrol 18, no. 1 (July 6, 2017): 218. https://doi.org/10.1186/s12882-017-0629-z.
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  - Wang, Xianwei, Yilong Wang, Uptal D. Patel, Huiman Xie Barnhart, Zixiao Li, Hao Li, Chunxue Wang, et al. “Comparison of Associations of Reduced Estimated Glomerular Filtration Rate With Stroke Outcomes Between Hypertension and No Hypertension.” Stroke 48, no. 6 (June 2017): 1691–94. https://doi.org/10.1161/STROKEAHA.117.016864.
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  - Roberts, John K., Sunil V. Rao, Linda K. Shaw, Dianne S. Gallup, Oscar C. Marroquin, and Uptal D. Patel. “Comparative Efficacy of Coronary Revascularization Procedures for Multivessel Coronary Artery Disease in Patients With Chronic Kidney Disease.” Am J Cardiol 119, no. 9 (May 1, 2017): 1344–51. https://doi.org/10.1016/j.amjcard.2017.01.029.
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  - Wang, Hanghang, Patrick H. Pun, Lydia Kwee, Damian Craig, Carol Haynes, Megan Chryst-Ladd, Laura P. Svetkey, et al. “Apolipoprotein L1 Genetic Variants Are Associated with Chronic Kidney Disease but Not with Cardiovascular Disease in a Population Referred for Cardiac Catheterization.” Cardiorenal Med 7, no. 2 (February 2017): 96–103. https://doi.org/10.1159/000453458.
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  - Block, Geoffrey A., David A. Bushinsky, John Cunningham, Tilman B. Drueke, Markus Ketteler, Reshma Kewalramani, Kevin J. Martin, et al. “Effect of Etelcalcetide vs Placebo on Serum Parathyroid Hormone in Patients Receiving Hemodialysis With Secondary Hyperparathyroidism: Two Randomized Clinical Trials.” Jama 317, no. 2 (January 10, 2017): 146–55. https://doi.org/10.1001/jama.2016.19456.
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  - Block, Geoffrey A., David A. Bushinsky, Sunfa Cheng, John Cunningham, Bastian Dehmel, Tilman B. Drueke, Markus Ketteler, et al. “Effect of Etelcalcetide vs Cinacalcet on Serum Parathyroid Hormone in Patients Receiving Hemodialysis With Secondary Hyperparathyroidism: A Randomized Clinical Trial.” Jama 317, no. 2 (January 10, 2017): 156–64. https://doi.org/10.1001/jama.2016.19468.
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  - Stanifer, John W., Francis Karia, Venance Maro, Kajiru Kilonzo, Xuejun Qin, Uptal D. Patel, and Elizabeth R. Hauser. “APOL1 risk alleles among individuals with CKD in Northern Tanzania: A pilot study.” Plos One 12, no. 7 (2017): e0181811. https://doi.org/10.1371/journal.pone.0181811.
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  - Zimmerman, Kanecia O., Huali Wu, Rachel Greenberg, Jeffrey T. Guptill, Kevin Hill, Uptal D. Patel, Lawrence Ku, et al. “Therapeutic Drug Monitoring, Electronic Health Records, and Pharmacokinetic Modeling to Evaluate Sirolimus Drug Exposure-Response Relationships in Renal Transplant Patients.” Ther Drug Monit 38, no. 5 (October 2016): 600–606. https://doi.org/10.1097/FTD.0000000000000313.
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  - Lunyera, Joseph, Daphne Wang, Venance Maro, Francis Karia, David Boyd, Justin Omolo, Uptal D. Patel, John W. Stanifer, and John W. Comprehensive Kidney Disease Assessment For Risk factors, epidemiology, Knowledge, and Attitudes (CKD AFRiKA) Study. “Traditional medicine practices among community members with diabetes mellitus in Northern Tanzania: an ethnomedical survey.” Bmc Complement Altern Med 16, no. 1 (August 11, 2016): 282. https://doi.org/10.1186/s12906-016-1262-2.
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  - Åkerblom, Axel, Robert M. Clare, Yuliya Lokhnygina, Lars Wallentin, Claes Held, Frans Van de Werf, David J. Moliterno, et al. “Albuminuria and cardiovascular events in patients with acute coronary syndromes: Results from the TRACER trial.” Am Heart J 178 (August 2016): 1–8. https://doi.org/10.1016/j.ahj.2016.04.013.
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  - Belley-Côté, Emilie P., Chirag R. Parikh, Colleen R. Shortt, Steven G. Coca, Amit X. Garg, John W. Eikelboom, Peter Kavsak, et al. “Association of cardiac biomarkers with acute kidney injury after cardiac surgery: A multicenter cohort study.” J Thorac Cardiovasc Surg 152, no. 1 (July 2016): 245-251.e4. https://doi.org/10.1016/j.jtcvs.2016.02.029.
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  - Yip, Wanfen, Charumathi Sabanayagam, Peng Guan Ong, Uptal D. Patel, Khuan Yew Chow, E Shyong Tai, Lieng H. Ling, Tien Yin Wong, and Carol Yim-Lui Cheung. “Joint Effect of Early Microvascular Damage in the Eye &Kidney on Risk of Cardiovascular Events.” Sci Rep 6 (June 8, 2016): 27442. https://doi.org/10.1038/srep27442.
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  - Stanifer, John W., Anthony Muiru, Tazeen H. Jafar, and Uptal D. Patel. “Chronic kidney disease in low- and middle-income countries.” Nephrol Dial Transplant 31, no. 6 (June 2016): 868–74. https://doi.org/10.1093/ndt/gfv466.
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  - Lunyera, Joseph, Dinushika Mohottige, Megan Von Isenburg, Marc Jeuland, Uptal D. Patel, and John W. Stanifer. “CKD of Uncertain Etiology: A Systematic Review.” Clin J Am Soc Nephrol 11, no. 3 (March 7, 2016): 379–85. https://doi.org/10.2215/CJN.07500715.
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  - Stanifer, John W., Joseph R. Egger, Elizabeth L. Turner, Nathan Thielman, Uptal D. Patel, and Uptal D. Comprehensive Kidney Disease Assessment for Risk factors, epidemiology, Knowledge, and Attitudes (CKD AFRiKA) Study. “Neighborhood clustering of non-communicable diseases: results from a community-based study in Northern Tanzania.” Bmc Public Health 16 (March 5, 2016): 226. https://doi.org/10.1186/s12889-016-2912-5.
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  - Vavalle, John P., Sean van Diepen, Robert M. Clare, Judith S. Hochman, W Douglas Weaver, Rajendra H. Mehta, Karen S. Pieper, et al. “Renal failure in patients with ST-segment elevation acute myocardial infarction treated with primary percutaneous coronary intervention: Predictors, clinical and angiographic features, and outcomes.” Am Heart J 173 (March 2016): 57–66. https://doi.org/10.1016/j.ahj.2015.12.001.
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  - Lunyera, Joseph, John W. Stanifer, Prossie Ingabire, Wilson Etolu, Peace Bagasha, Joseph R. Egger, Uptal D. Patel, Gerald Mutungi, and Robert Kalyesubula. “Prevalence and correlates of proteinuria in Kampala, Uganda: a cross-sectional pilot study.” Bmc Res Notes 9 (February 16, 2016): 97. https://doi.org/10.1186/s13104-016-1897-6.
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  - Stanifer, John W., Charles R. Cleland, Gerald Jamberi Makuka, Joseph R. Egger, Venance Maro, Honest Maro, Francis Karia, Uptal D. Patel, Matthew J. Burton, and Heiko Philippin. “Prevalence, Risk Factors, and Complications of Diabetes in the Kilimanjaro Region: A Population-Based Study from Tanzania.” Plos One 11, no. 10 (2016): e0164428. https://doi.org/10.1371/journal.pone.0164428.
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  - Stanifer, John W., Elizabeth L. Turner, Joseph R. Egger, Nathan Thielman, Francis Karia, Venance Maro, Kajiru Kilonzo, Uptal D. Patel, and Karen Yeates. “Knowledge, Attitudes, and Practices Associated with Chronic Kidney Disease in Northern Tanzania: A Community-Based Study.” Plos One 11, no. 6 (2016): e0156336. https://doi.org/10.1371/journal.pone.0156336.
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  - Friedman, Daniel J., Jagmeet P. Singh, Jeptha P. Curtis, WH Wilson Tang, Haikun Bao, Erica S. Spatz, Adrian F. Hernandez, Uptal D. Patel, and Sana M. Al-Khatib. “Comparative Effectiveness of CRT-D Versus Defibrillator Alone in HF Patients With Moderate-to-Severe Chronic Kidney Disease.” J Am Coll Cardiol 66, no. 23 (December 15, 2015): 2618–29. https://doi.org/10.1016/j.jacc.2015.09.097.
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  - Koyner, Jay L., Steven G. Coca, Heather Thiessen-Philbrook, Uptal D. Patel, Michael G. Shlipak, Amit X. Garg, Chirag R. Parikh, Chirag R. Translational Research Investigating Biomarker Endpoints for Acute Kidney Injury (TRIBE-AKI) Consortium, and Chirag R. Translational Research Investigating Biomarker Endpoints for Acute Kidney Injury TRIBE-AKI Consortium. “Urine Biomarkers and Perioperative Acute Kidney Injury: The Impact of Preoperative Estimated GFR.” Am J Kidney Dis 66, no. 6 (December 2015): 1006–14. https://doi.org/10.1053/j.ajkd.2015.07.027.
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  - Stanifer, John W., Joseph Lunyera, David Boyd, Francis Karia, Venance Maro, Justin Omolo, and Uptal D. Patel. “Traditional medicine practices among community members with chronic kidney disease in northern Tanzania: an ethnomedical survey.” Bmc Nephrol 16 (October 23, 2015): 170. https://doi.org/10.1186/s12882-015-0161-y.
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  - Drawz, Paul E., Patrick Archdeacon, Clement J. McDonald, Neil R. Powe, Kimberly A. Smith, Jenna Norton, Desmond E. Williams, Uptal D. Patel, and Andrew Narva. “CKD as a Model for Improving Chronic Disease Care through Electronic Health Records.” Clin J Am Soc Nephrol 10, no. 8 (August 7, 2015): 1488–99. https://doi.org/10.2215/CJN.00940115.
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  - Trachtman, H., A. Frymoyer, A. Lewandowski, L. A. Greenbaum, D. I. Feig, D. S. Gipson, B. A. Warady, et al. “Pharmacokinetics, Pharmacodynamics, and Safety of Lisinopril in Pediatric Kidney Transplant Patients: Implications for Starting Dose Selection.” Clin Pharmacol Ther 98, no. 1 (July 2015): 25–33. https://doi.org/10.1002/cpt.127.
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  - Englum, Brian R., Matthew A. Schechter, William D. Irish, Kadiyala V. Ravindra, Deepak S. Vikraman, Scott L. Sanoff, Matthew J. Ellis, Debra L. Sudan, and Uptal D. Patel. “Outcomes in kidney transplant recipients from older living donors.” Transplantation 99, no. 2 (February 2015): 309–15. https://doi.org/10.1097/TP.0000000000000607.
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  - Kostoff, R. N., and U. Patel. “Literature-related discovery and innovation: Chronic kidney disease.” Technological Forecasting and Social Change 91 (February 1, 2015): 341–51. https://doi.org/10.1016/j.techfore.2014.09.013.
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  - Wang, Virginia, Bradley G. Hammill, Matthew L. Maciejewski, Rasheeda K. Hall, Lynn Van Scoyoc, Amit X. Garg, Arsh K. Jain, and Uptal D. Patel. “Impact of automated reporting of estimated glomerular filtration rate in the veterans health administration.” Med Care 53, no. 2 (February 2015): 177–83. https://doi.org/10.1097/MLR.0000000000000275.
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  - Moledina, Dennis G., Chirag R. Parikh, Amit X. Garg, Heather Thiessen-Philbrook, Jay L. Koyner, Uptal D. Patel, Prasad Devarajan, Michael G. Shlipak, Steven G. Coca, and Steven G. TRIBE-AKI Consortium. “Association of Perioperative Plasma Neutrophil Gelatinase-Associated Lipocalin Levels with 3-Year Mortality after Cardiac Surgery: A Prospective Observational Cohort Study.” Plos One 10, no. 6 (2015): e0129619. https://doi.org/10.1371/journal.pone.0129619.
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  - Stanifer, John W., Francis Karia, Corrine I. Voils, Elizabeth L. Turner, Venance Maro, Dionis Shimbi, Humphrey Kilawe, Matayo Lazaro, and Uptal D. Patel. “Development and validation of a cross-cultural knowledge, attitudes, and practices survey instrument for chronic kidney disease in a Swahili-speaking population.” Plos One 10, no. 3 (2015): e0121722. https://doi.org/10.1371/journal.pone.0121722.
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  - Stanifer, John W., Uptal D. Patel, Francis Karia, Nathan Thielman, Venance Maro, Dionis Shimbi, Humphrey Kilaweh, et al. “The determinants of traditional medicine use in Northern Tanzania: a mixed-methods study.” Plos One 10, no. 4 (2015): e0122638. https://doi.org/10.1371/journal.pone.0122638.
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  - Stanifer, John W., Venance Maro, Joseph Egger, Francis Karia, Nathan Thielman, Elizabeth L. Turner, Dionis Shimbi, Humphrey Kilaweh, Oliver Matemu, and Uptal D. Patel. “The epidemiology of chronic kidney disease in Northern Tanzania: a population-based survey.” Plos One 10, no. 4 (2015): e0124506. https://doi.org/10.1371/journal.pone.0124506.
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  - Tsai, Thomas T., Uptal D. Patel, Tara I. Chang, Kevin F. Kennedy, Frederick A. Masoudi, Michael E. Matheny, Mikhail Kosiborod, et al. “Validated contemporary risk model of acute kidney injury in patients undergoing percutaneous coronary interventions: insights from the National Cardiovascular Data Registry Cath-PCI Registry.” J Am Heart Assoc 3, no. 6 (December 2014): e001380. https://doi.org/10.1161/JAHA.114.001380.
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  - Middleton, John P., and Uptal D. Patel. “The need for collaboration to improve cardiovascular outcomes in patients with CKD.” Adv Chronic Kidney Dis 21, no. 6 (November 2014): 456–59. https://doi.org/10.1053/j.ackd.2014.08.007.
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  - Tuttle, Katherine R., George L. Bakris, Rudolf W. Bilous, Jane L. Chiang, Ian H. de Boer, Jordi Goldstein-Fuchs, Irl B. Hirsch, et al. “Diabetic kidney disease: a report from an ADA Consensus Conference.” Am J Kidney Dis 64, no. 4 (October 2014): 510–33. https://doi.org/10.1053/j.ajkd.2014.08.001.
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  - Tuttle, Katherine R., George L. Bakris, Rudolf W. Bilous, Jane L. Chiang, Ian H. de Boer, Jordi Goldstein-Fuchs, Irl B. Hirsch, et al. “Diabetic kidney disease: a report from an ADA Consensus Conference.” Diabetes Care 37, no. 10 (October 2014): 2864–83. https://doi.org/10.2337/dc14-1296.
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  - Khan, Usman A., Steven G. Coca, Kwangik Hong, Jay L. Koyner, Amit X. Garg, Cary S. Passik, Madhav Swaminathan, et al. “Blood transfusions are associated with urinary biomarkers of kidney injury in cardiac surgery.” J Thorac Cardiovasc Surg 148, no. 2 (August 2014): 726–32. https://doi.org/10.1016/j.jtcvs.2013.09.080.
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  - Hornik, Christoph P., Catherine D. Krawczeski, Michael Zappitelli, Kwangik Hong, Heather Thiessen-Philbrook, Prasad Devarajan, Chirag R. Parikh, Uptal D. Patel, and Uptal D. TRIBE-AKI Consortium. “Serum brain natriuretic peptide and risk of acute kidney injury after cardiac operations in children.” Ann Thorac Surg 97, no. 6 (June 2014): 2142–47. https://doi.org/10.1016/j.athoracsur.2014.02.035.
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  - Coca, Steven G., Amit X. Garg, Heather Thiessen-Philbrook, Jay L. Koyner, Uptal D. Patel, Harlan M. Krumholz, Michael G. Shlipak, Chirag R. Parikh, and Chirag R. TRIBE-AKI Consortium. “Urinary biomarkers of AKI and mortality 3 years after cardiac surgery.” J Am Soc Nephrol 25, no. 5 (May 2014): 1063–71. https://doi.org/10.1681/ASN.2013070742.
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  - Inrig, Jula K., Robert M. Califf, Asba Tasneem, Radha K. Vegunta, Christopher Molina, John W. Stanifer, Karen Chiswell, and Uptal D. Patel. “The landscape of clinical trials in nephrology: a systematic review of Clinicaltrials.gov.” Am J Kidney Dis 63, no. 5 (May 2014): 771–80. https://doi.org/10.1053/j.ajkd.2013.10.043.
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  - Pálsson, Ragnar, and Uptal D. Patel. “Cardiovascular complications of diabetic kidney disease.” Adv Chronic Kidney Dis 21, no. 3 (May 2014): 273–80. https://doi.org/10.1053/j.ackd.2014.03.003.
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  - Patel, Uptal D. “Outcomes after pediatric kidney transplantation improving: how can we do even better?” Pediatrics 133, no. 4 (April 2014): 734–35. https://doi.org/10.1542/peds.2014-0124.
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  - Stanifer, John W., Bocheng Jing, Scott Tolan, Nicole Helmke, Romita Mukerjee, Saraladevi Naicker, and Uptal Patel. “The epidemiology of chronic kidney disease in sub-Saharan Africa: a systematic review and meta-analysis.” Lancet Glob Health 2, no. 3 (March 2014): e174–81. https://doi.org/10.1016/S2214-109X(14)70002-6.
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  - Tsai, Thomas T., Uptal D. Patel, Tara I. Chang, Kevin F. Kennedy, Frederick A. Masoudi, Michael E. Matheny, Mikhail Kosiborod, et al. “Contemporary incidence, predictors, and outcomes of acute kidney injury in patients undergoing percutaneous coronary interventions: insights from the NCDR Cath-PCI registry.” Jacc Cardiovasc Interv 7, no. 1 (January 2014): 1–9. https://doi.org/10.1016/j.jcin.2013.06.016.
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  - Tyson, Crystal C., Maragatha Kuchibhatla, Uptal D. Patel, Patrick H. Pun, Alex Chang, Chinazo Nwankwo, Michael A. Joseph, and Laura P. Svetkey. “Impact of Kidney Function on Effects of the Dietary Approaches to Stop Hypertension (Dash) Diet.” J Hypertens (Los Angel) 3 (2014). https://doi.org/10.4172/2167-1095.1000168.
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  - Wang, Virginia, Matthew L. Maciejewski, Bradley G. Hammill, Rasheeda K. Hall, Lynn Van Scoyoc, Amit X. Garg, Arsh K. Jain, and Uptal D. Patel. “Recognition of CKD after the introduction of automated reporting of estimated GFR in the Veterans Health Administration.” Clin J Am Soc Nephrol 9, no. 1 (January 2014): 29–36. https://doi.org/10.2215/CJN.02490213.
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  - St Peter, Wendy L., Lori D. Wazny, and Uptal D. Patel. “New models of chronic kidney disease care including pharmacists: improving medication reconciliation and medication management.” Curr Opin Nephrol Hypertens 22, no. 6 (November 2013): 656–62. https://doi.org/10.1097/MNH.0b013e328365b364.
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  - Bashir, Mustafa R., Tracy A. Jaffe, Todd V. Brennan, Uptal D. Patel, and Matthew J. Ellis. “Renal transplant imaging using magnetic resonance angiography with a nonnephrotoxic contrast agent.” Transplantation 96, no. 1 (July 15, 2013): 91–96. https://doi.org/10.1097/TP.0b013e318295464c.
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  - Parikh, Chirag R., Heather Thiessen-Philbrook, Amit X. Garg, Deepak Kadiyala, Michael G. Shlipak, Jay L. Koyner, Charles L. Edelstein, et al. “Performance of kidney injury molecule-1 and liver fatty acid-binding protein and combined biomarkers of AKI after cardiac surgery.” Clin J Am Soc Nephrol 8, no. 7 (July 2013): 1079–88. https://doi.org/10.2215/CJN.10971012.
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  - Tyson, Crystal C., Lawrence J. Appel, William M. Vollmer, Gerald J. Jerome, Phillip J. Brantley, Jack F. Hollis, Victor J. Stevens, Jamy D. Ard, Uptal D. Patel, and Laura P. Svetkey. “Impact of 5-year weight change on blood pressure: results from the Weight Loss Maintenance trial.” J Clin Hypertens (Greenwich) 15, no. 7 (July 2013): 458–64. https://doi.org/10.1111/jch.12108.
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  - Hooper, David K., Jason C. Williams, Adam C. Carle, Sandra Amaral, Deepa H. Chand, Maria E. Ferris, Hiren P. Patel, et al. “The quality of cardiovascular disease care for adolescents with kidney disease: a Midwest Pediatric Nephrology Consortium study.” Pediatr Nephrol 28, no. 6 (June 2013): 939–49. https://doi.org/10.1007/s00467-013-2419-6.
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  - Koyner, Jay L., Amit X. Garg, Michael G. Shlipak, Uptal D. Patel, Kyaw Sint, Kwangik Hong, Prasad Devarajan, et al. “Urinary cystatin C and acute kidney injury after cardiac surgery.” Am J Kidney Dis 61, no. 5 (May 2013): 730–38. https://doi.org/10.1053/j.ajkd.2012.12.006.
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  - Boer, Ian H. de, Grant A. Olan, Uptal D. Patel, and Uptal D. American Society of Nephrology Chronic Kidney Disease Advisory Group. “Screening for chronic kidney disease.” Ann Intern Med 158, no. 5 Pt 1 (March 5, 2013): 362–63. https://doi.org/10.7326/0003-4819-158-5-201303050-00016.
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  - Wang, Virginia, Matthew L. Maciejewski, Uptal D. Patel, Karen M. Stechuchak, Denise M. Hynes, and Morris Weinberger. “Comparison of outcomes for veterans receiving dialysis care from VA and non-VA providers.” Bmc Health Serv Res 13 (January 18, 2013): 26. https://doi.org/10.1186/1472-6963-13-26.
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  - McCullough, Peter A., Huiman X. Barnhart, Jula K. Inrig, Donal Reddan, Shelly Sapp, Uptal D. Patel, Ajay K. Singh, Lynda A. Szczech, and Robert M. Califf. “Cardiovascular toxicity of epoetin-alfa in patients with chronic kidney disease.” Am J Nephrol 37, no. 6 (2013): 549–58. https://doi.org/10.1159/000351175.
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  - Spahillari, Aferdita, Chirag R. Parikh, Kyaw Sint, Jay L. Koyner, Uptal D. Patel, Charles L. Edelstein, Cary S. Passik, et al. “Serum cystatin C- versus creatinine-based definitions of acute kidney injury following cardiac surgery: a prospective cohort study.” Am J Kidney Dis 60, no. 6 (December 2012): 922–29. https://doi.org/10.1053/j.ajkd.2012.06.002.
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  - Molnar, Amber O., Chirag R. Parikh, Kyaw Sint, Steven G. Coca, Jay Koyner, Uptal D. Patel, Isabel Butrymowicz, Michael Shlipak, and Amit X. Garg. “Association of postoperative proteinuria with AKI after cardiac surgery among patients at high risk.” Clin J Am Soc Nephrol 7, no. 11 (November 2012): 1749–60. https://doi.org/10.2215/CJN.13421211.
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  - Inrig, Jula K., Huiman X. Barnhart, Donal Reddan, Uptal D. Patel, Shelly Sapp, Robert M. Califf, Ajay K. Singh, and Lynda A. Szczech. “Effect of hemoglobin target on progression of kidney disease: a secondary analysis of the CHOIR (Correction of Hemoglobin and Outcomes in Renal Insufficiency) trial.” Am J Kidney Dis 60, no. 3 (September 2012): 390–401. https://doi.org/10.1053/j.ajkd.2012.03.009.
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  - Inrig, Jula K., Shelly Sapp, Huiman Barnhart, Uptal D. Patel, Donal Reddan, Ajay Singh, Robert M. Califf, and Lynda Szczech. “Impact of higher hemoglobin targets on blood pressure and clinical outcomes: a secondary analysis of CHOIR.” Nephrol Dial Transplant 27, no. 9 (September 2012): 3606–14. https://doi.org/10.1093/ndt/gfs123.
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  - Hall, Rasheeda K., Virginia Wang, George L. Jackson, Bradley G. Hammill, Matthew L. Maciejewski, Elizabeth M. Yano, Laura P. Svetkey, and Uptal D. Patel. “Implementation of automated reporting of estimated glomerular filtration rate among Veterans Affairs laboratories: a retrospective study.” Bmc Med Inform Decis Mak 12 (July 12, 2012): 69. https://doi.org/10.1186/1472-6947-12-69.
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  - Powers, Benjamin J., Remy R. Coeytaux, Rowena J. Dolor, Vic Hasselblad, Uptal D. Patel, William S. Yancy, Rebecca N. Gray, R Julian Irvine, Amy S. Kendrick, and Gillian D. Sanders. “Updated report on comparative effectiveness of ACE inhibitors, ARBs, and direct renin inhibitors for patients with essential hypertension: much more data, little new information.” J Gen Intern Med 27, no. 6 (June 2012): 716–29. https://doi.org/10.1007/s11606-011-1938-8.
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  - Koyner, Jay L., Amit X. Garg, Steven G. Coca, Kyaw Sint, Heather Thiessen-Philbrook, Uptal D. Patel, Michael G. Shlipak, Chirag R. Parikh, and Chirag R. TRIBE-AKI Consortium. “Biomarkers predict progression of acute kidney injury after cardiac surgery.” J Am Soc Nephrol 23, no. 5 (May 2012): 905–14. https://doi.org/10.1681/ASN.2011090907.
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  - Patel, Uptal D., and Kevin A. Schulman. “Invited Commentary-Can We Begin With the End in Mind? End-of-Life Care Preferences Before Long-term Dialysis.” Arch Intern Med 172, no. 8 (April 23, 2012): 663–64. https://doi.org/10.1001/archinternmed.2012.1151.
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  - Schell, Jane O., Uptal D. Patel, Karen E. Steinhauser, Natalie Ammarell, and James A. Tulsky. “Discussions of the kidney disease trajectory by elderly patients and nephrologists: a qualitative study.” Am J Kidney Dis 59, no. 4 (April 2012): 495–503. https://doi.org/10.1053/j.ajkd.2011.11.023.
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  - Patel, Uptal D., Amit X. Garg, Harlan M. Krumholz, Michael G. Shlipak, Steven G. Coca, Kyaw Sint, Heather Thiessen-Philbrook, et al. “Preoperative serum brain natriuretic peptide and risk of acute kidney injury after cardiac surgery.” Circulation 125, no. 11 (March 20, 2012): 1347–55. https://doi.org/10.1161/CIRCULATIONAHA.111.029686.
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  - Inrig, Jula K., Suzanne K. Bryskin, Uptal D. Patel, Murat Arcasoy, and Lynda A. Szczech. “Association between high-dose erythropoiesis-stimulating agents, inflammatory biomarkers, and soluble erythropoietin receptors.” Bmc Nephrol 12 (December 12, 2011): 67. https://doi.org/10.1186/1471-2369-12-67.
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  - Tsai, Thomas T., John C. Messenger, J Matthew Brennan, Uptal D. Patel, David Dai, Robert N. Piana, Kevin J. Anstrom, et al. “Safety and efficacy of drug-eluting stents in older patients with chronic kidney disease: a report from the linked CathPCI Registry-CMS claims database.” J Am Coll Cardiol 58, no. 18 (October 25, 2011): 1859–69. https://doi.org/10.1016/j.jacc.2011.06.056.
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  - Wang, Virginia, Shoou-Yih D. Lee, Uptal D. Patel, Matthew L. Maciejewski, and Thomas C. Ricketts. “Longitudinal analysis of market factors associated with provision of peritoneal dialysis services.” Med Care Res Rev 68, no. 5 (October 2011): 537–58. https://doi.org/10.1177/1077558711399768.
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  - Mehta, Rajendra H., Emily Honeycutt, Uptal D. Patel, Renato D. Lopes, Judson B. Williams, Linda K. Shaw, Sean M. O’Brien, Robert M. Califf, G Chad Hughes, and Michael H. Sketch. “Relationship of the time interval between cardiac catheterization and elective coronary artery bypass surgery with postprocedural acute kidney injury.” Circulation 124, no. 11 Suppl (September 13, 2011): S149–55. https://doi.org/10.1161/CIRCULATIONAHA.110.011700.
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  - Parikh, Chirag R., Steven G. Coca, Heather Thiessen-Philbrook, Michael G. Shlipak, Jay L. Koyner, Zhu Wang, Charles L. Edelstein, et al. “Postoperative biomarkers predict acute kidney injury and poor outcomes after adult cardiac surgery.” J Am Soc Nephrol 22, no. 9 (September 2011): 1748–57. https://doi.org/10.1681/ASN.2010121302.
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  - Parikh, Dipen S., Jula K. Inrig, Adam Kipp, Lynda A. Szczech, William McClellan, and Uptal D. Patel. “Veterans more likely to start hemodialysis with an arteriovenous fistula.” Semin Dial 24, no. 5 (September 2011): 570–75. https://doi.org/10.1111/j.1525-139X.2011.00920.x.
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  - Roberts, John K., and Uptal D. Patel. “Management of coronary artery disease in end-stage renal disease.” Semin Dial 24, no. 5 (September 2011): 525–32. https://doi.org/10.1111/j.1525-139X.2011.00948.x.
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  - Shlipak, Michael G., Steven G. Coca, Zhu Wang, Prasad Devarajan, Jay L. Koyner, Uptal D. Patel, Heather Thiessen-Philbrook, Amit X. Garg, Chirag R. Parikh, and Chirag R. TRIBE-AKI Consortium. “Presurgical serum cystatin C and risk of acute kidney injury after cardiac surgery.” Am J Kidney Dis 58, no. 3 (September 2011): 366–73. https://doi.org/10.1053/j.ajkd.2011.03.015.
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  - Cannizzaro, Leon A., Jonathan P. Piccini, Uptal D. Patel, and Adrian F. Hernandez. “Device therapy in heart failure patients with chronic kidney disease.” J Am Coll Cardiol 58, no. 9 (August 23, 2011): 889–96. https://doi.org/10.1016/j.jacc.2011.05.024.
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  - Orlando, Lori A., Eric J. Belasco, Uptal D. Patel, and David B. Matchar. “The chronic kidney disease model: a general purpose model of disease progression and treatment.” Bmc Med Inform Decis Mak 11 (June 16, 2011): 41. https://doi.org/10.1186/1472-6947-11-41.
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  - Kagoma, Yoan K., Matthew A. Weir, Arthur V. Iansavichus, Brenda R. Hemmelgarn, Ayub Akbari, Uptal D. Patel, Amit X. Garg, and Arsh K. Jain. “Impact of estimated GFR reporting on patients, clinicians, and health-care systems: a systematic review.” Am J Kidney Dis 57, no. 4 (April 2011): 592–601. https://doi.org/10.1053/j.ajkd.2010.08.029.
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  - Mehta, Rajendra H., Emily Honeycutt, Uptal D. Patel, Renato D. Lopes, Linda K. Shaw, Donald D. Glower, Robert A. Harrington, Robert M. Califf, and Michael H. Sketch. “Impact of recovery of renal function on long-term mortality after coronary artery bypass grafting.” Am J Cardiol 106, no. 12 (December 15, 2010): 1728–34. https://doi.org/10.1016/j.amjcard.2010.07.045.
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  - Tsai, Thomas T., John C. Messenger, J Matthew Brennan, Uptal D. Patel, David Dai, Robert Piana, Kevin J. Anstrom, et al. “Contemporary Risk of Follow-up Adverse Events in Older Patients with Chronic Kidney Disease and Dialysis Undergoing Percutaneous Coronary Interventions: A Report from the Merged NCDR CMS Registry.” Circulation 122, no. 21 (November 23, 2010).
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  - Sedor, John R., Suzanne Watnick, Uptal D. Patel, Alfred Cheung, William Harmon, Jonathan Himmelfarb, Thomas H. Hostetter, et al. “ASN End-Stage Renal Disease Task Force: perspective on prospective payments for renal dialysis facilities.” J Am Soc Nephrol 21, no. 8 (August 2010): 1235–37. https://doi.org/10.1681/ASN.2010060656.
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  - Parikh, Dipen S., Madhav Swaminathan, Laura E. Archer, Jula K. Inrig, Lynda A. Szczech, Andrew D. Shaw, and Uptal D. Patel. “Perioperative outcomes among patients with end-stage renal disease following coronary artery bypass surgery in the USA.” Nephrol Dial Transplant 25, no. 7 (July 2010): 2275–83. https://doi.org/10.1093/ndt/gfp781.
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  - Patel, Uptal D., Melissa A. Greiner, Gregg C. Fonarow, Hemant Phatak, Adrian F. Hernandez, and Lesley H. Curtis. “Associations between worsening renal function and 30-day outcomes among Medicare beneficiaries hospitalized with heart failure.” Am Heart J 160, no. 1 (July 2010): 132-138.e1. https://doi.org/10.1016/j.ahj.2010.03.033.
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  - Wang, Virginia, Shoou-Yih D. Lee, Uptal D. Patel, Bryan J. Weiner, Thomas C. Ricketts, and Morris Weinberger. “Geographic and temporal trends in peritoneal dialysis services in the United States between 1995 and 2003.” Am J Kidney Dis 55, no. 6 (June 2010): 1079–87. https://doi.org/10.1053/j.ajkd.2010.01.022.
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  - Swaminathan, Madhav, Christopher C. C. Hudson, Barbara G. Phillips-Bute, Uptal D. Patel, Joseph P. Mathew, Mark F. Newman, Carmelo A. Milano, Andrew D. Shaw, and Mark Stafford-Smith. “Impact of early renal recovery on survival after cardiac surgery-associated acute kidney injury.” Ann Thorac Surg 89, no. 4 (April 2010): 1098–1104. https://doi.org/10.1016/j.athoracsur.2009.12.018.
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  - Szczech, Lynda A., Huiman X. Barnhart, Shelly Sapp, G Michael Felker, Adrian Hernandez, Donal Reddan, Robert M. Califf, Jula K. Inrig, Uptal D. Patel, and Ajay K. Singh. “A secondary analysis of the CHOIR trial shows that comorbid conditions differentially affect outcomes during anemia treatment.” Kidney Int 77, no. 3 (February 2010): 239–46. https://doi.org/10.1038/ki.2009.415.
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  - Patel, Uptal D. “Fetal origins of renal disparities.” Semin Nephrol 30, no. 1 (January 2010): 42–50. https://doi.org/10.1016/j.semnephrol.2009.10.002.
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  - Palevsky, P. M., J. H. Zhang, T. Z. O’Connor, G. M. Chertow, S. T. Crowley, D. Choudhury, K. Finkel, et al. “Intensity of renal support in critically ill patients with acute kidney injury (New England Journal of Medicine (2008) 359, (7-20)).” New England Journal of Medicine 361, no. 24 (December 10, 2009): 2391. https://doi.org/10.1056/NEJMx090062.
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  - Inrig, Jula K., Uptal D. Patel, Robert D. Toto, Donal N. Reddan, Jonathan Himmelfarb, Robert M. Lindsay, John Stivelman, James F. Winchester, and Lynda A. Szczech. “Decreased pulse pressure during hemodialysis is associated with improved 6-month outcomes.” Kidney Int 76, no. 10 (November 2009): 1098–1107. https://doi.org/10.1038/ki.2009.340.
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  - Inrig, Jula K., Uptal D. Patel, Robert D. Toto, and Lynda A. Szczech. “Association of blood pressure increases during hemodialysis with 2-year mortality in incident hemodialysis patients: a secondary analysis of the Dialysis Morbidity and Mortality Wave 2 Study.” Am J Kidney Dis 54, no. 5 (November 2009): 881–90. https://doi.org/10.1053/j.ajkd.2009.05.012.
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  - Swaminathan, Madhav, Barbara G. Phillips-Bute, Uptal D. Patel, Andrew D. Shaw, Mark Stafford-Smith, Pamela S. Douglas, Laura E. Archer, Peter K. Smith, and Joseph P. Mathew. “Increasing healthcare resource utilization after coronary artery bypass graft surgery in the United States.” Circ Cardiovasc Qual Outcomes 2, no. 4 (July 2009): 305–12. https://doi.org/10.1161/CIRCOUTCOMES.108.831016.
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  - Lu, Jonathan C. T., Steven G. Coca, Uptal D. Patel, Lloyd Cantley, Chirag R. Parikh, and Chirag R. Translational Research Investigating Biomarkers and Endpoints for Acute Kidney Injury (TRIBE-AKI) Consortium. “Searching for genes that matter in acute kidney injury: a systematic review.” Clin J Am Soc Nephrol 4, no. 6 (June 2009): 1020–31. https://doi.org/10.2215/CJN.05411008.
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  - Ellis, M. J., C. R. Parikh, J. K. Inrig, M. Kambay, and U. D. Patel. “Erratum: Chronic kidney disease after hematopoietic cell transplantation: A systematic review (American Journal of Transplantation (2008) 8:11 (2378-2390) DOI: 10.1111/j.1600-6143.2008.02408.x).” American Journal of Transplantation 9, no. 4 (April 1, 2009): 865. https://doi.org/10.1111/j.1600-6143.2009.02584.x.
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  - Patel, Uptal D., Fang-Shu Ou, E Magnus Ohman, W Brian Gibler, Charles V. Pollack, Eric D. Peterson, and Matthew T. Roe. “Hospital performance and differences by kidney function in the use of recommended therapies after non-ST-elevation acute coronary syndromes.” Am J Kidney Dis 53, no. 3 (March 2009): 426–37. https://doi.org/10.1053/j.ajkd.2008.09.024.
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  - Patwardhan, Meenal B., Kensaku Kawamoto, David Lobach, Uptal D. Patel, and David B. Matchar. “Recommendations for a clinical decision support for the management of individuals with chronic kidney disease.” Clin J Am Soc Nephrol 4, no. 2 (February 2009): 273–83. https://doi.org/10.2215/CJN.02590508.
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  - Martinelli, Susan M., Uptal D. Patel, Barbara G. Phillips-Bute, Carmelo A. Milano, Laura E. Archer, Mark Stafford-Smith, Andrew D. Shaw, and Madhav Swaminathan. “Trends in cardiac surgery-associated acute renal failure in the United States: a disproportionate increase after heart transplantation.” Ren Fail 31, no. 8 (2009): 633–40. https://doi.org/10.3109/08860220903100689.
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  - Nicoara, Alina, Uptal D. Patel, Barbara G. Phillips-Bute, Andrew D. Shaw, Mark Stafford-Smith, Carmelo A. Milano, and Madhav Swaminathan. “Mortality trends associated with acute renal failure requiring dialysis after CABG surgery in the United States.” Blood Purif 28, no. 4 (2009): 359–63. https://doi.org/10.1159/000235856.
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  - Hudson, Christopher, Jordan Hudson, Madhav Swaminathan, Andrew Shaw, Mark Stafford-Smith, and Uptal D. Patel. “Emerging concepts in acute kidney injury following cardiac surgery.” Semin Cardiothorac Vasc Anesth 12, no. 4 (December 2008): 320–30. https://doi.org/10.1177/1089253208328582.
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  - Ellis, M. J., C. R. Parikh, J. K. Inrig, M. Kanbay, and U. D. Patel. “Chronic kidney disease after hematopoietic cell transplantation: a systematic review.” Am J Transplant 8, no. 11 (November 2008): 2378–90. https://doi.org/10.1111/j.1600-6143.2008.02408.x.
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  - Novak, James E., Jula K. Inrig, Uptal D. Patel, Robert M. Califf, and Lynda A. Szczech. “Negative trials in nephrology: what can we learn?” Kidney Int 74, no. 9 (November 2008): 1121–27. https://doi.org/10.1038/ki.2008.286.
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  - Patel, Uptal D., Joshua Grab, Mikhail Kosiborod, Barbara Lytle, Eric D. Peterson, and Karen P. Alexander. “Impact of anemia on physical function and survival among patients with coronary artery disease.” Clin Cardiol 31, no. 11 (November 2008): 546–50. https://doi.org/10.1002/clc.20283.
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  - Patel, Uptal D., Adrian F. Hernandez, Li Liang, Eric D. Peterson, Kenneth A. LaBresh, Clyde W. Yancy, Nancy M. Albert, Gray Ellrodt, and Gregg C. Fonarow. “Quality of care and outcomes among patients with heart failure and chronic kidney disease: A Get With the Guidelines -- Heart Failure Program study.” Am Heart J 156, no. 4 (October 2008): 674–81. https://doi.org/10.1016/j.ahj.2008.05.028.
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  - Provenzale, J. M., K. Shah, U. Patel, and D. C. McCrory. “Systematic review of CT and MR perfusion imaging for assessment of acute cerebrovascular disease.” Ajnr Am J Neuroradiol 29, no. 8 (September 2008): 1476–82. https://doi.org/10.3174/ajnr.A1161.
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  - Szczech, Lynda A., Huiman X. Barnhart, Jula K. Inrig, Donal N. Reddan, Shelly Sapp, Robert M. Califf, Uptal D. Patel, and Ajay K. Singh. “Secondary analysis of the CHOIR trial epoetin-alpha dose and achieved hemoglobin outcomes.” Kidney Int 74, no. 6 (September 2008): 791–98. https://doi.org/10.1038/ki.2008.295.
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  - VA/NIH Acute Renal Failure Trial Network, Peter, Paul M. Palevsky, Jane Hongyuan Zhang, Theresa Z. O’Connor, Glenn M. Chertow, Susan T. Crowley, Devasmita Choudhury, et al. “Intensity of renal support in critically ill patients with acute kidney injury.” N Engl J Med 359, no. 1 (July 3, 2008): 7–20. https://doi.org/10.1056/NEJMoa0802639.
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  - Stafford-Smith, Mark, Uptal D. Patel, Barbara G. Phillips-Bute, Andrew D. Shaw, and Madhav Swaminathan. “Acute kidney injury and chronic kidney disease after cardiac surgery.” Adv Chronic Kidney Dis 15, no. 3 (July 2008): 257–77. https://doi.org/10.1053/j.ackd.2008.04.006.
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  - Ferris, Maria, Uptal D. Patel, Susan Massengill, Debbie Gipson, William Conley, J Bradley Layton, Shashi Nagaraj, and William Primack. “Pediatric chronic kidney disease in North Carolina.” N C Med J 69, no. 3 (May 2008): 208–14.
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  - Inrig, Jula K., Uptal D. Patel, Libbie P. Briley, Lilin She, Barbara S. Gillespie, J Donald Easton, Eric J. Topol, and Lynda A. Szczech. “Mortality, kidney disease and cardiac procedures following acute coronary syndrome.” Nephrol Dial Transplant 23, no. 3 (March 2008): 934–40. https://doi.org/10.1093/ndt/gfm689.
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  - Matchar, David B., Douglas C. McCrory, Lori A. Orlando, Manesh R. Patel, Uptal D. Patel, Meenal B. Patwardhan, Benjamin Powers, Gregory P. Samsa, and Rebecca N. Gray. “Systematic review: comparative effectiveness of angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers for treating essential hypertension.” Ann Intern Med 148, no. 1 (January 1, 2008): 16–29. https://doi.org/10.7326/0003-4819-148-1-200801010-00189.
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  - Inrig, Jula K., Barbara S. Gillespie, Uptal D. Patel, Libbie P. Briley, Lilin She, J Donald Easton, Eric Topol, and Lynda A. Szczech. “Risk for cardiovascular outcomes among subjects with atherosclerotic cardiovascular disease and greater-than-normal estimated glomerular filtration rate.” Clin J Am Soc Nephrol 2, no. 6 (November 2007): 1215–22. https://doi.org/10.2215/CJN.00930207.
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  - Swaminathan, Madhav, Andrew D. Shaw, Barbara G. Phillips-Bute, Patricia L. McGugan-Clark, Laura E. Archer, Steven Talbert, Carmelo A. Milano, Uptal D. Patel, and Mark Stafford-Smith. “Trends in acute renal failure associated with coronary artery bypass graft surgery in the United States.” Crit Care Med 35, no. 10 (October 2007): 2286–91. https://doi.org/10.1097/01.ccm.0000282079.05994.57.
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  - Inrig, Jula K., Uptal D. Patel, Barbara S. Gillespie, Vic Hasselblad, Jonathan Himmelfarb, Donal Reddan, Robert M. Lindsay, et al. “Relationship between interdialytic weight gain and blood pressure among prevalent hemodialysis patients.” Am J Kidney Dis 50, no. 1 (July 2007): 108-118.e4. https://doi.org/10.1053/j.ajkd.2007.04.020.
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  - Inrig, J. K., E. Z. Oddone, V. Hasselblad, Barbara Gillespie, U. D. Patel, D. Reddan, R. Toto, et al. “Association of intradialytic blood pressure changes with hospitalization and mortality rates in prevalent ESRD patients.” Kidney Int 71, no. 5 (March 2007): 454–61. https://doi.org/10.1038/sj.ki.5002077.
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  - Ellis, Matthew J., and Uptal D. Patel. “Hematopoietic stem-cell transplantation.” N Engl J Med 355, no. 10 (September 7, 2006): 1070. https://doi.org/10.1056/NEJMc061443.
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  - Patel, Uptal D., and Matthew M. Davis. “Falling into the doughnut hole: drug spending among beneficiaries with end-stage renal disease under Medicare Part D plans.” J Am Soc Nephrol 17, no. 9 (September 2006): 2546–53. https://doi.org/10.1681/ASN.2005121385.
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  - Patel, Uptal D., and Matthew M. Davis. “Physicians' attitudes and practices regarding adherence to medical regimens by patients with chronic illness.” Clin Pediatr (Phila) 45, no. 5 (June 2006): 439–45. https://doi.org/10.1177/0009922806289619.
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  - Han, Jin H., Abhinav Chandra, Jyotsna Mulgund, Matthew T. Roe, Eric D. Peterson, Lynda A. Szczech, Uptal Patel, E Magnus Ohman, Christopher J. Lindsell, and W Brian Gibler. “Chronic kidney disease in patients with non-ST-segment elevation acute coronary syndromes.” Am J Med 119, no. 3 (March 2006): 248–54. https://doi.org/10.1016/j.amjmed.2005.08.057.
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  - Patel, Uptal D., Eric W. Young, Akinlolu O. Ojo, and Rodney A. Hayward. “CKD progression and mortality among older patients with diabetes.” Am J Kidney Dis 46, no. 3 (September 2005): 406–14. https://doi.org/10.1053/j.ajkd.2005.05.027.
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  - Patel, Uptal D., Harry Hollander, and Sanjay Saint. “Clinical problem-solving. Index of suspicion.” N Engl J Med 350, no. 19 (May 6, 2004): 1990–95. https://doi.org/10.1056/NEJMcps032937.
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  - Patel, U. D., T. A. Mottes, and J. T. Flynn. “Delayed compared with immediate use of peritoneal catheter in pediatric peritoneal dialysis.” Adv Perit Dial 17 (2001): 253–59.
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  - Saint, S., J. Wiese, J. K. Amory, M. L. Bernstein, U. D. Patel, J. K. Zemencuk, S. J. Bernstein, B. A. Lipsky, and T. P. Hofer. “Are physicians aware of which of their patients have indwelling urinary catheters?” Am J Med 109, no. 6 (October 15, 2000): 476–80. https://doi.org/10.1016/s0002-9343(00)00531-3.
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- Book Sections
  - Patel, U. D., and S. E. Thomas. “Evaluation of the Candidate.” In Pediatric Solid Organ Transplantation, 153–60, 2009. https://doi.org/10.1002/9781444312720.ch17.
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- Conference Papers
  - Goldfarb, David A. “Re: Renal transplant imaging using magnetic resonance angiography with a nonnephrotoxic contrast agent.” In J Urol, 190:2175, 2013. https://doi.org/10.1016/j.juro.2013.08.058.
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Scholarly, Clinical, & Service Activities
Outreach & Engaged Scholarship
- Bass Connections Faculty Team Member. Spirituality, Self-management and Chronic Disease among Ethnic Groups of Robeson County, North Carolina. August 2016 - May 2017 2016 - 2017

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Education, Training, & Certifications

Duke Appointment History

Subject Headings

Global Scholarship

Research

Selected Grants

External Relationships

Selected Publications

Academic Articles

Book Sections

Conference Papers

Outreach & Engaged Scholarship