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Vadim Y Arshavsky

Helena Rubinstein Foundation Distinguished Professor of Ophthalmology
Ophthalmology, Vitreoretinal Diseases & Surgery
Box 3802 Med Ctr, Durham, NC 27710
Duke Eye Center, 2351 Erwin Rd. Box 3802, 5012 Aeri, Durham, NC 27710

Scholarly Works - Book sections


Light-Driven Translocation of Signaling Proteins in Vertebrate Photoreceptors

Book section · January 1, 2025 Sustained illumination causes massive translocation of three signal transduction proteins, transducin, arrestin and recoverin, into and out of the outer segment compartment of rod and cone photoreceptors. This phenomenon is thought to contribute to photore ... Full text Cite

Photoreceptor Outer Segment Disc Morphogenesis

Book section · January 1, 2025 The photoreceptor outer segment is a ciliary organelle specialized to produce electrical signals in response to light stimuli. The outer segment contains a stack of flattened membranous “discs” which provide vast surface areas for light capture. The outer ... Full text Cite

The role of dopamine in fine-tuning cone- and rod-driven vision

Book section · January 1, 2014 Dopamine, one of the major neuromodulators in the retina, acts through dopamine D1, D2, and D4 G-protein-coupled receptors localized to many types of retinal neurons. This expansive expression pattern allows dopamine to regulate visual processing at differ ... Full text Cite

Light-driven translocation of signaling proteins in vertebrate photoreceptors

Book section · January 1, 2010 Sustained illumination causes massive translocation of at least three signal transduction proteins (transducin, arrestin, and recoverin) into and out of the outer segment compartment of rod and cone photoreceptors. This phenomenon is thought to contribute ... Full text Cite

Light-driven translocation of signaling proteins in vertebrate photoreceptors

Book section · January 1, 2010 Sustained illumination causes massive translocation of at least three signal transduction proteins (transducin, arrestin, and recoverin) into and out of the outer segment compartment of rod and cone photoreceptors. This phenomenon is thought to contribute ... Full text Cite

Biology and functions of the RGS9 isoforms.

Book section · 2009 Two splice isoforms of the ninth member of the regulator of G protein signaling (RGS) protein family are expressed in the nervous system, where they are engaged in such diverse functions as vision and behavior. RGS9-1 regulates phototransduction in rods an ... Full text Link to item Cite