Overview
My research has focused on cancer cell metabolism and the molecular pathways that regulate posttranslational modifications. In addition, we explore cancer initiation, cell survival, progression, and metastasis using a variety of in vitro, ex vivo, and in vivo genetical approaches, including gene knockdown, CRISPR/Cas9 knockout, molecular biology techniques, biochemical approaches, and genetically engineered mouse and Nude mice models, to characterize molecular mechanisms regulated by metabolic pathways and develop potential metabolic strategies for cancer therapy.
