Vivian Hou Chu | Scholars@Duke

Vivian Hou Chu
Associate Professor

Dr. Chu's clinical research is focused on staphylococci and endocarditis (IE). She is the director of the International Collaboration on Endocarditis (ICE), a group of investigators from 78 sites in 32 countries worldwide that is dedicated to further the understanding of infective endocarditis. The ICE database comprises > 5000 cases of endocarditis and is designed to answer questions that could not be answered from a single-center study. The current focus of this group is surgical-decision making in the treatment of endocarditis. Another major focus of Dr. Chu's research is on the relationship between oral hygiene and risk for developing infective endocarditis.

Current Appointments & Affiliations

Associate Professor, Medicine, Infectious Diseases, Medicine 2017
Member in the Duke Clinical Research Institute, Duke Clinical Research Institute, Institutes and Centers 2006

Contact Information

Duke Box 102359, DIV of Infectious Diseases, Durham, NC 27710
Room 177 Hanes House, Trent Drive, Durham, NC 27710
vivian.chu@duke.edu (919) 668-7174

Background
Education, Training, & Certifications
- Fellow in Infectious Diseases, Medicine, Duke University 2003 - 2006
- Medical Resident, Medicine, Duke University 2000 - 2003
- M.D., Columbia University 2000
Duke Appointment History
- Associate Professor of Medicine, Medicine, Infectious Diseases, Medicine 2013 - 2017
- Assistant Professor of Medicine, Medicine, Infectious Diseases, Medicine 2008 - 2013
- Medical Instructor in the Department of Medicine, Medicine, Infectious Diseases, Medicine 2006 - 2008
- Instructor, Temporary in the Department of Medicine, Medicine, Infectious Diseases, Medicine 2006
Recognition
Awards & Honors
- Infectious Disease Division Annual Education Award. Division of Infectious Diseases, Department of Medicine, Duke. 2015
Research
Selected Grants
- Duke Summer Training in Academic Research (Duke's STAR) awarded by National Institutes of Health 2018 - 2023
- Bridging the Gap to Enhance Clinical Research Program (BIGGER) awarded by National Institutes of Health 2016 - 2021
- PTN2- TO# 3 Concept Development and Clinical Trial Readiness Support Option Period 1 2019 - 2020
- Oral Hygiene, Periodontal Disease and Infective Endocarditis awarded by Carolinas Medical Center 2018 - 2020
- Optimizing treatment for E. faecalis infective endocarditis: ampicillin plus ceftriaxone versus ampicillin plus gentamicin awarded by National Institutes of Health 2016 - 2019
- Duke CTSA (UL1) awarded by National Institutes of Health 2013 - 2018
- NIH Summer Research Experience Programs (R25) awarded by National Institutes of Health 2013 - 2018
- DCRI Sub BAA-NIAID-DMID-NIHAI2005025 awarded by National Institutes of Health 2010 - 2017
- Optimizing duration of antibiotics after valve surgery for infective endocarditis awarded by National Institutes of Health 2012 - 2014
Industry Relationships
- Theravance, Inc
- UpToDate
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Wang, Andrew, Vivian H. Chu, Eugene Athan, Francois Delahaye, Tomas Freiberger, Cristiane Lamas, Jose M. Miro, et al. “Corrigendum to "association between the timing of surgery for complicated, left-sided infective endocarditis and survival", American HeartJournal 2019, volume 210, April 2019, pages 108-116..” Am Heart J 212 (June 2019). https://doi.org/10.1016/j.ahj.2019.03.006.
    Full Text Link to Item
  - Hannan, Margaret M., Rongbing Xie, Jennifer Cowger, Stephan Schueler, Theo de By, Anne I. Dipchand, Vivian H. Chu, et al. “Epidemiology of infection in mechanical circulatory support: A global analysis from the ISHLT Mechanically Assisted Circulatory Support Registry..” J Heart Lung Transplant 38, no. 4 (April 2019): 364–73. https://doi.org/10.1016/j.healun.2019.01.007.
    Full Text Link to Item
  - Wang, Andrew, Vivian H. Chu, Eugene Athan, Francois Delahaye, Tomas Freiberger, Cristiane Lamas, Jose M. Miro, et al. “Association between the timing of surgery for complicated, left-sided infective endocarditis and survival..” Am Heart J 210 (April 2019): 108–16. https://doi.org/10.1016/j.ahj.2019.01.004.
    Full Text Link to Item
  - Thornhill, Martin H., Mark J. Dayer, Vivian H. Chu, Patrick T. O’Gara, and Larry M. Baddour. “Reply: Intravenous Drug Use-Associated Endocarditis Complicating Research of Antibiotic Prophylaxis and Guideline Recommendations..” J Am Coll Cardiol 73, no. 8 (March 5, 2019): 985–86. https://doi.org/10.1016/j.jacc.2019.01.001.
    Full Text Link to Item
  - Schranz, Asher J., Aaron Fleischauer, Vivian H. Chu, Li-Tzy Wu, and David L. Rosen. “Trends in Drug Use-Associated Infective Endocarditis and Heart Valve Surgery, 2007 to 2017: A Study of Statewide Discharge Data..” Ann Intern Med 170, no. 1 (January 1, 2019): 31–40. https://doi.org/10.7326/M18-2124.
    Full Text Link to Item
  - Arnold, Christopher J., and Vivian H. Chu. “Cardiovascular Implantable Electronic Device Infections..” Infect Dis Clin North Am 32, no. 4 (December 2018): 811–25. https://doi.org/10.1016/j.idc.2018.06.004.
    Full Text Link to Item
  - Chu, Vivian H. “Device-Associated Infections..” Infect Dis Clin North Am 32, no. 4 (December 2018): ix–x. https://doi.org/10.1016/j.idc.2018.09.001.
    Full Text Link to Item
  - Thornhill, Martin H., Teresa B. Gibson, Eli Cutler, Mark J. Dayer, Vivian H. Chu, Peter B. Lockhart, Patrick T. O’Gara, and Larry M. Baddour. “Antibiotic Prophylaxis and Incidence of Endocarditis Before and After the 2007 AHA Recommendations..” J Am Coll Cardiol 72, no. 20 (November 13, 2018): 2443–54. https://doi.org/10.1016/j.jacc.2018.08.2178.
    Full Text Link to Item
  - Wang, Andrew, Jeffrey G. Gaca, and Vivian H. Chu. “Injection Drug Use-Associated Infective Endocarditis-Reply..” Jama 320, no. 18 (November 13, 2018): 1939–40. https://doi.org/10.1001/jama.2018.14075.
    Full Text Link to Item
  - Holland, Thomas L., Issam Raad, Helen W. Boucher, Deverick J. Anderson, Sara E. Cosgrove, P Suzanne Aycock, John W. Baddley, et al. “Effect of Algorithm-Based Therapy vs Usual Care on Clinical Success and Serious Adverse Events in Patients with Staphylococcal Bacteremia: A Randomized Clinical Trial..” Jama 320, no. 12 (September 25, 2018): 1249–58. https://doi.org/10.1001/jama.2018.13155.
    Full Text Link to Item
  - Aslam, Saima, Rongbing Xie, Jennifer Cowger, James K. Kirklin, Vivian H. Chu, Stephan Schueler, Theo de By, et al. “Bloodstream infections in mechanical circulatory support device recipients in the International Society of Heart and Lung Transplantation Mechanically Assisted Circulation Support Registry: Epidemiology, risk factors, and mortality..” J Heart Lung Transplant 37, no. 8 (August 2018): 1013–20. https://doi.org/10.1016/j.healun.2018.04.006.
    Full Text Link to Item
  - Chu, Vivian H. “Endocarditis..” Jama 320, no. 1 (July 3, 2018). https://doi.org/10.1001/jama.2018.7524.
    Full Text Link to Item
  - Wang, Andrew, Jeffrey G. Gaca, and Vivian H. Chu. “Management Considerations in Infective Endocarditis: A Review..” Jama 320, no. 1 (July 3, 2018): 72–83. https://doi.org/10.1001/jama.2018.7596.
    Full Text Link to Item
  - Pericàs, J. M., J. A. Messina, C. Garcia-de-la-Mària, L. Park, B. K. Sharma-Kuinkel, F. Marco, D. Wray, et al. “Influence of vancomycin minimum inhibitory concentration on the outcome of methicillin-susceptible Staphylococcus aureus left-sided infective endocarditis treated with antistaphylococcal β-lactam antibiotics: a prospective cohort study by the International Collaboration on Endocarditis..” Clin Microbiol Infect 23, no. 8 (August 2017): 544–49. https://doi.org/10.1016/j.cmi.2017.01.017.
    Full Text Link to Item
  - Carugati, M., C. A. Petti, C. Arnold, J. M. Miro, J. M. Pericàs, C. Garcia de la Maria, Z. Kanafani, et al. “Antistaphylococcal β-Lactams versus Vancomycin for Treatment of Infective Endocarditis Due to Methicillin-Susceptible Coagulase-Negative Staphylococci: a Prospective Cohort Study from the International Collaboration on Endocarditis..” Antimicrob Agents Chemother 60, no. 10 (October 2016): 6341–49. https://doi.org/10.1128/AAC.01531-16.
    Full Text Link to Item
  - Romaine, Andrew, Daniel Ye, Zachary Ao, Francia Fang, Octavious Johnson, Taylor Blake, Daniel K. Benjamin, et al. “Safety of histamine-2 receptor blockers in hospitalized VLBW infants..” Early Hum Dev 99 (August 2016): 27–30. https://doi.org/10.1016/j.earlhumdev.2016.05.010.
    Full Text Link to Item
  - Limeres Posse, J., M. Álvarez Fernández, J. Fernández Feijoo, J. Medina Henríquez, P. B. Lockhart, V. H. Chu, and P. Diz Dios. “Intravenous amoxicillin/clavulanate for the prevention of bacteraemia following dental procedures: a randomized clinical trial..” J Antimicrob Chemother 71, no. 7 (July 2016): 2022–30. https://doi.org/10.1093/jac/dkw081.
    Full Text Link to Item
  - Park, Lawrence P., Vivian H. Chu, Gail Peterson, Athanasios Skoutelis, Tatjana Lejko-Zupa, Emilio Bouza, Pierre Tattevin, et al. “Validated Risk Score for Predicting 6-Month Mortality in Infective Endocarditis..” J Am Heart Assoc 5, no. 4 (April 18, 2016). https://doi.org/10.1161/JAHA.115.003016.
    Full Text Link to Item
  - Gulack, Brian C., Matthew M. Laughon, Reese H. Clark, Terrance Burgess, Sybil Robinson, Abdurrauf Muhammad, Angela Zhang, et al. “Enteral Feeding with Human Milk Decreases Time to Discharge in Infants following Gastroschisis Repair..” J Pediatr 170 (March 2016): 85–89. https://doi.org/10.1016/j.jpeds.2015.11.046.
    Full Text Link to Item
  - Qi, Robert, Hwang-Soo Joo, Batu Sharma-Kuinkel, Nicholas R. Berlon, Lawrence Park, Chih-Lung Fu, Julia A. Messina, et al. “Increased in vitro phenol-soluble modulin production is associated with soft tissue infection source in clinical isolates of methicillin-susceptible Staphylococcus aureus..” J Infect 72, no. 3 (March 2016): 302–8. https://doi.org/10.1016/j.jinf.2015.11.002.
    Full Text Link to Item
  - Tsalik, Ephraim L., Yanhong Li, Lori L. Hudson, Vivian H. Chu, Tiffany Himmel, Alex T. Limkakeng, Jason N. Katz, et al. “Potential Cost-effectiveness of Early Identification of Hospital-acquired Infection in Critically Ill Patients..” Ann Am Thorac Soc 13, no. 3 (March 2016): 401–13. https://doi.org/10.1513/AnnalsATS.201504-205OC.
    Full Text Open Access Copy Link to Item
  - Chu, Vivian H. “When the Cat's Out of the Bag: Searching for Portals of Entry in Infective Endocarditis..” J Am Coll Cardiol 67, no. 2 (January 19, 2016): 159–61. https://doi.org/10.1016/j.jacc.2015.10.066.
    Full Text Link to Item
  - Chu, Vivian H., Lawrence P. Park, Eugene Athan, Francois Delahaye, Tomas Freiberger, Cristiane Lamas, Jose M. Miro, et al. “Response to Letter Regarding Article, "Association Between Surgical Indications, Operative Risk, and Clinical Outcome in Infective Endocarditis: A Prospective Study From the International Collaboration on Endocarditis"..” Circulation 132, no. 14 (October 6, 2015): e184–85. https://doi.org/10.1161/CIRCULATIONAHA.115.016782.
    Full Text Link to Item
  - Arnold, Christopher J., Jessica Ericson, Nathan Cho, James Tian, Shelby Wilson, Vivian H. Chu, Christoph P. Hornik, et al. “Cefepime and Ceftazidime Safety in Hospitalized Infants..” Pediatr Infect Dis J 34, no. 9 (September 2015): 964–68. https://doi.org/10.1097/INF.0000000000000778.
    Full Text Link to Item
  - Ericson, Jessica E., Christopher Arnold, Jomani Cheeseman, Jordan Cho, Sarah Kaneko, Ele’na Wilson, Reese H. Clark, et al. “Use and Safety of Erythromycin and Metoclopramide in Hospitalized Infants..” J Pediatr Gastroenterol Nutr 61, no. 3 (September 2015): 334–39. https://doi.org/10.1097/MPG.0000000000000792.
    Full Text Link to Item
  - Lauridsen, Trine K., Lawrence Park, Steven Y. C. Tong, Christine Selton-Suty, Gail Peterson, Enrico Cecchi, Luis Afonso, et al. “Echocardiographic Findings Predict In-Hospital and 1-Year Mortality in Left-Sided Native Valve Staphylococcus aureus Endocarditis: Analysis From the International Collaboration on Endocarditis-Prospective Echo Cohort Study..” Circ Cardiovasc Imaging 8, no. 7 (July 2015). https://doi.org/10.1161/CIRCIMAGING.114.003397.
    Full Text Link to Item
  - Arnold, Christopher J., Jessica Ericson, Jordan Kohman, Kaitlyn L. Corey, Morgan Oh, Janet Onabanjo, Christoph P. Hornik, et al. “Rifampin use and safety in hospitalized infants..” Am J Perinatol 32, no. 6 (May 2015): 565–70. https://doi.org/10.1055/s-0034-1543955.
    Full Text Link to Item
  - Arnold, Christopher J., Melissa Johnson, Arnold S. Bayer, Suzanne Bradley, Efthymia Giannitsioti, José M. Miró, Pilar Tornos, et al. “Candida infective endocarditis: an observational cohort study with a focus on therapy..” Antimicrob Agents Chemother 59, no. 4 (April 2015): 2365–73. https://doi.org/10.1128/AAC.04867-14.
    Full Text Link to Item
  - Chirouze, Catherine, François Alla, Vance G. Fowler, Daniel J. Sexton, G Ralph Corey, Vivian H. Chu, Andrew Wang, et al. “Impact of early valve surgery on outcome of Staphylococcus aureus prosthetic valve infective endocarditis: analysis in the International Collaboration of Endocarditis-Prospective Cohort Study..” Clin Infect Dis 60, no. 5 (March 1, 2015): 741–49. https://doi.org/10.1093/cid/ciu871.
    Full Text Link to Item
  - Delahaye, F., V. H. Chu, J. Altclas, B. Barsic, A. Delahaye, T. Freiberger, D. L. Gordon, et al. “One-year outcome following biological or mechanical valve replacement for infective endocarditis..” Int J Cardiol 178 (January 15, 2015): 117–23. https://doi.org/10.1016/j.ijcard.2014.10.125.
    Full Text Link to Item
  - Chu, Vivian H., Lawrence P. Park, Eugene Athan, Francois Delahaye, Tomas Freiberger, Cristiane Lamas, Jose M. Miro, et al. “Association between surgical indications, operative risk, and clinical outcome in infective endocarditis: a prospective study from the International Collaboration on Endocarditis..” Circulation 131, no. 2 (January 13, 2015): 131–40. https://doi.org/10.1161/CIRCULATIONAHA.114.012461.
    Full Text Link to Item
  - Alagna, L., L. P. Park, B. P. Nicholson, A. J. Keiger, J. Strahilevitz, A. Morris, D. Wray, et al. “Repeat endocarditis: analysis of risk factors based on the International Collaboration on Endocarditis - Prospective Cohort Study..” Clin Microbiol Infect 20, no. 6 (June 2014): 566–75. https://doi.org/10.1111/1469-0691.12395.
    Full Text Link to Item
  - Bin Abdulhak, Aref A., Larry M. Baddour, Patricia J. Erwin, Bruno Hoen, Vivian H. Chu, George A. Mensah, and Imad M. Tleyjeh. “Global and regional burden of infective endocarditis, 1990-2010: a systematic review of the literature..” Glob Heart 9, no. 1 (March 2014): 131–43. https://doi.org/10.1016/j.gheart.2014.01.002.
    Full Text Link to Item
  - Carugati, Manuela, Arnold S. Bayer, Josè M. Miró, Lawrence P. Park, Armenio C. Guimarães, Athanasios Skoutelis, Claudio Q. Fortes, et al. “High-dose daptomycin therapy for left-sided infective endocarditis: a prospective study from the international collaboration on endocarditis..” Antimicrob Agents Chemother 57, no. 12 (December 2013): 6213–22. https://doi.org/10.1128/AAC.01563-13.
    Full Text Link to Item
  - Chirouze, C., E. Athan, F. Alla, V. H. Chu, G. Ralph Corey, C. Selton-Suty, M. -. L. Erpelding, et al. “Enterococcal endocarditis in the beginning of the 21st century: analysis from the International Collaboration on Endocarditis-Prospective Cohort Study..” Clin Microbiol Infect 19, no. 12 (December 2013): 1140–47. https://doi.org/10.1111/1469-0691.12166.
    Full Text Link to Item
  - Lalani, Tahaniyat, Vivian H. Chu, Lawrence P. Park, Enrico Cecchi, G Ralph Corey, Emanuele Durante-Mangoni, Vance G. Fowler, et al. “In-hospital and 1-year mortality in patients undergoing early surgery for prosthetic valve endocarditis..” Jama Intern Med 173, no. 16 (September 9, 2013): 1495–1504. https://doi.org/10.1001/jamainternmed.2013.8203.
    Full Text Link to Item
  - Barsic, Bruno, Andrew Wang, and Vivian H. Chu. “Reply to Tleyjeh and Baddour..” Clin Infect Dis 56, no. 12 (June 2013). https://doi.org/10.1093/cid/cit101.
    Full Text Link to Item
  - Chu, Vivian H., and Daniel J. Sexton. “Editorial commentary: telephone consultation for Staphylococcus aureus bacteremia: opening Pandora's box..” Clin Infect Dis 56, no. 4 (February 2013): 536–38. https://doi.org/10.1093/cid/cis895.
    Full Text Link to Item
  - Barsic, Bruno, Stuart Dickerman, Vladimir Krajinovic, Paul Pappas, Javier Altclas, Giampiero Carosi, José H. Casabé, et al. “Influence of the timing of cardiac surgery on the outcome of patients with infective endocarditis and stroke..” Clin Infect Dis 56, no. 2 (January 2013): 209–17. https://doi.org/10.1093/cid/cis878.
    Full Text Link to Item
  - Chambers, Stephen T., David Murdoch, Arthur Morris, David Holland, Paul Pappas, Manel Almela, Nuria Fernández-Hidalgo, et al. “HACEK infective endocarditis: characteristics and outcomes from a large, multi-national cohort..” Plos One 8, no. 5 (2013). https://doi.org/10.1371/journal.pone.0063181.
    Full Text Link to Item
  - Athan, Eugene, Vivian H. Chu, Pierre Tattevin, Christine Selton-Suty, Phillip Jones, Christoph Naber, José M. Miró, et al. “Clinical characteristics and outcome of infective endocarditis involving implantable cardiac devices..” Jama 307, no. 16 (April 25, 2012): 1727–35. https://doi.org/10.1001/jama.2012.497.
    Full Text Link to Item
  - Federspiel, Jerome J., Sally C. Stearns, Amanda F. Peppercorn, Vivian H. Chu, and Vance G. Fowler. “Increasing US rates of endocarditis with Staphylococcus aureus: 1999-2008..” Arch Intern Med 172, no. 4 (February 27, 2012): 363–65. https://doi.org/10.1001/archinternmed.2011.1027.
    Full Text Link to Item
  - Kiefer, Todd, Lawrence Park, Christophe Tribouilloy, Claudia Cortes, Roberta Casillo, Vivian Chu, Francois Delahaye, et al. “Association between valvular surgery and mortality among patients with infective endocarditis complicated by heart failure..” Jama 306, no. 20 (November 23, 2011): 2239–47. https://doi.org/10.1001/jama.2011.1701.
    Full Text Link to Item
  - Dickerman, Stuart A., Bruno Barsic, Vivian H. Chu, V. G. Fowler, Paul A. Pappas, and Arnold Bayer. “Medical vs. Surgical Management of Perivalvular Abscess in Infective Endocarditis: A Propensity Analysis From the International Collaboration on Endocarditis Prospective Cohort Study (ICE-PCS).” Circulation 124, no. 21 (November 22, 2011).
    Link to Item
  - Goswami, Neela D., Melissa D. Johnson, and Vivian H. Chu. “Ertapenem for treatment of osteomyelitis: a case series..” Bmc Res Notes 4 (November 2, 2011). https://doi.org/10.1186/1756-0500-4-478.
    Full Text Link to Item
  - Nienaber, Juhsien J. C., Batu K. Sharma Kuinkel, Michael Clarke-Pearson, Supaporn Lamlertthon, Lawrence Park, Thomas H. Rude, Steve Barriere, et al. “Methicillin-susceptible Staphylococcus aureus endocarditis isolates are associated with clonal complex 30 genotype and a distinct repertoire of enterotoxins and adhesins..” J Infect Dis 204, no. 5 (September 1, 2011): 704–13. https://doi.org/10.1093/infdis/jir389.
    Full Text Link to Item
  - Thornhill, Martin H., Mark J. Dayer, Jamie M. Forde, G Ralph Corey, Vivian H. Chu, David J. Couper, and Peter B. Lockhart. “Impact of the NICE guideline recommending cessation of antibiotic prophylaxis for prevention of infective endocarditis: before and after study..” Bmj 342 (May 3, 2011). https://doi.org/10.1136/bmj.d2392.
    Full Text Link to Item
  - Lalani, Tahaniyat, Christopher H. Cabell, Daniel K. Benjamin, Ovidiu Lasca, Christoph Naber, Vance G. Fowler, G Ralph Corey, et al. “Analysis of the impact of early surgery on in-hospital mortality of native valve endocarditis: use of propensity score and instrumental variable methods to adjust for treatment-selection bias..” Circulation 121, no. 8 (March 2, 2010): 1005–13. https://doi.org/10.1161/CIRCULATIONAHA.109.864488.
    Full Text Open Access Copy Link to Item
  - Eisen, Damon P., G Ralph Corey, Emma S. McBryde, Vance G. Fowler, Jose M. Miro, Chris H. Cabell, Alan C. Street, et al. “Reduced valve replacement surgery and complication rate in Staphylococcus aureus endocarditis patients receiving acetyl-salicylic acid..” J Infect 58, no. 5 (May 2009): 332–38. https://doi.org/10.1016/j.jinf.2009.03.006.
    Full Text Link to Item
  - Chu, V. H., J. M. Miro, B. Hoen, C. H. Cabell, P. A. Pappas, P. Jones, M. E. Stryjewski, et al. “Coagulase-negative staphylococcal prosthetic valve endocarditis--a contemporary update based on the International Collaboration on Endocarditis: prospective cohort study..” Heart 95, no. 7 (April 2009): 570–76. https://doi.org/10.1136/hrt.2008.152975.
    Full Text Link to Item
  - Murdoch, David R., G Ralph Corey, Bruno Hoen, José M. Miró, Vance G. Fowler, Arnold S. Bayer, Adolf W. Karchmer, et al. “Clinical presentation, etiology, and outcome of infective endocarditis in the 21st century: the International Collaboration on Endocarditis-Prospective Cohort Study..” Arch Intern Med 169, no. 5 (March 9, 2009): 463–73. https://doi.org/10.1001/archinternmed.2008.603.
    Full Text Link to Item
  - Stryjewski, Martin E., Zeina A. Kanafani, Vivian H. Chu, Paul A. Pappas, Tina Harding, Laura A. Drew, Daniel K. Benjamin, et al. “Staphylococcus aureus bacteremia among patients with health care-associated fever..” Am J Med 122, no. 3 (March 2009): 281-289.e2. https://doi.org/10.1016/j.amjmed.2008.09.040.
    Full Text Link to Item
  - Chu, V. H., J. M. Miro, B. Hoen, C. H. Cabell, P. A. Pappas, P. Jones, M. E. Stryjewski, et al. “Coagulase-negative staphylococcal prosthetic valve endocarditis-a contemporary update based on the International Collaboration on Endocarditis: Prospective cohort study.” Heart 95, no. 7 (2009): 570–76. https://doi.org/10.1136/hrt.2008.149575.
    Full Text
  - Monk, Alastair B., Sam Boundy, Vivian H. Chu, Jill C. Bettinger, Jaime R. Robles, Vance G. Fowler, and Gordon L. Archer. “Analysis of the genotype and virulence of Staphylococcus epidermidis isolates from patients with infective endocarditis..” Infect Immun 76, no. 11 (November 2008): 5127–32. https://doi.org/10.1128/IAI.00606-08.
    Full Text Link to Item
  - Lalani, Tahaniyat, Jerome J. Federspiel, Helen W. Boucher, Thomas H. Rude, In-Gyu Bae, Michael J. Rybak, Giang T. Tonthat, et al. “Associations between the genotypes of Staphylococcus aureus bloodstream isolates and clinical characteristics and outcomes of bacteremic patients..” J Clin Microbiol 46, no. 9 (September 2008): 2890–96. https://doi.org/10.1128/JCM.00905-08.
    Full Text Link to Item
  - Baddley, J. W., D. K. Benjamin, M. Patel, J. Miró, E. Athan, B. Barsic, E. Bouza, et al. “Candida infective endocarditis..” Eur J Clin Microbiol Infect Dis 27, no. 7 (July 2008): 519–29. https://doi.org/10.1007/s10096-008-0466-x.
    Full Text Link to Item
  - Chu, Vivian H. “Coagulase-negative staphylococci and endocarditis: reappraisal in the 21st century..” Enferm Infecc Microbiol Clin 26, no. 5 (May 2008): 261–62. https://doi.org/10.1157/13120416.
    Full Text Link to Item
  - Liao, L., D. F. Kong, Z. Samad, P. A. Pappas, J. G. Jollis, S. S. Lin, A. Wang, et al. “Echocardiographic risk stratification for early surgery with endocarditis: a cost-effectiveness analysis..” Heart 94, no. 5 (May 2008). https://doi.org/10.1136/hrt.2006.106716.
    Full Text Link to Item
  - Petti, Cathy A., Keith E. Simmon, Jose M. Miro, Bruno Hoen, Francesc Marco, Vivian H. Chu, Eugene Athan, et al. “Genotypic diversity of coagulase-negative staphylococci causing endocarditis: a global perspective..” J Clin Microbiol 46, no. 5 (May 2008): 1780–84. https://doi.org/10.1128/JCM.02405-07.
    Full Text Link to Item
  - Chu, Vivian H., Christopher W. Woods, Jose M. Miro, Bruno Hoen, Christopher H. Cabell, Paul A. Pappas, Jerome Federspiel, et al. “Emergence of coagulase-negative staphylococci as a cause of native valve endocarditis..” Clin Infect Dis 46, no. 2 (January 15, 2008): 232–42. https://doi.org/10.1086/524666.
    Full Text Link to Item
  - Lalani, Tahaniyat, Vivian H. Chu, Chelsea A. Grussemeyer, Shelby D. Reed, Michael P. Bolognesi, Joelle Y. Friedman, Robert I. Griffiths, et al. “Clinical outcomes and costs among patients with Staphylococcus aureus bacteremia and orthopedic device infections..” Scand J Infect Dis 40, no. 11–12 (2008): 973–77. https://doi.org/10.1080/00365540802245146.
    Full Text Link to Item
  - Morpeth, Susan, David Murdoch, Christopher H. Cabell, Adolf W. Karchmer, Paul Pappas, Donald Levine, Francisco Nacinovich, et al. “Non-HACEK gram-negative bacillus endocarditis..” Ann Intern Med 147, no. 12 (December 18, 2007): 829–35. https://doi.org/10.7326/0003-4819-147-12-200712180-00002.
    Full Text Link to Item
  - Stryjewski, Martin E., Russell P. Hall, Vivian H. Chu, Zeina A. Kanafani, William D. O’Riordan, Michael S. Weinstock, R Scott Stienecker, et al. “Expression of antimicrobial peptides in the normal and involved skin of patients with infective cellulitis..” J Infect Dis 196, no. 9 (November 1, 2007): 1425–30. https://doi.org/10.1086/522630.
    Full Text Link to Item
  - Chu, Vivian H., and Arnold S. Bayer. “Use of echocardiography in the diagnosis and management of infective endocarditis..” Curr Infect Dis Rep 9, no. 4 (July 2007): 283–90. https://doi.org/10.1007/s11908-007-0044-x.
    Full Text Link to Item
  - Aksoy, Olcay, Daniel J. Sexton, Andrew Wang, Paul A. Pappas, Wissam Kourany, Vivian Chu, Vance G. Fowler, et al. “Early surgery in patients with infective endocarditis: a propensity score analysis..” Clin Infect Dis 44, no. 3 (February 1, 2007): 364–72. https://doi.org/10.1086/510583.
    Full Text Link to Item
  - Stryjewski, Martin E., Lynda A. Szczech, Daniel K. Benjamin, Jula K. Inrig, Zeina A. Kanafani, John J. Engemann, Vivian H. Chu, et al. “Use of vancomycin or first-generation cephalosporins for the treatment of hemodialysis-dependent patients with methicillin-susceptible Staphylococcus aureus bacteremia..” Clin Infect Dis 44, no. 2 (January 15, 2007): 190–96. https://doi.org/10.1086/510386.
    Full Text Link to Item
  - Lalani, T., Z. A. Kanafani, V. H. Chu, L. Moore, G. R. Corey, P. Pappas, C. W. Woods, et al. “Prosthetic valve endocarditis due to coagulase-negative staphylococci: findings from the International Collaboration on Endocarditis Merged Database..” Eur J Clin Microbiol Infect Dis 25, no. 6 (June 2006): 365–68. https://doi.org/10.1007/s10096-006-0141-z.
    Full Text Link to Item
  - Stryjewski, Martin E., Vivian H. Chu, William D. O’Riordan, Brian L. Warren, Lala M. Dunbar, David M. Young, Marc Vallée, et al. “Telavancin versus standard therapy for treatment of complicated skin and skin structure infections caused by gram-positive bacteria: FAST 2 study..” Antimicrob Agents Chemother 50, no. 3 (March 2006): 862–67. https://doi.org/10.1128/AAC.50.3.862-867.2006.
    Full Text Link to Item
  - Chu, Vivian H., David R. Crosslin, Joelle Y. Friedman, Shelby D. Reed, Christopher H. Cabell, Robert I. Griffiths, Leah E. Masselink, et al. “Staphylococcus aureus bacteremia in patients with prosthetic devices: costs and outcomes..” Am J Med 118, no. 12 (December 2005). https://doi.org/10.1016/j.amjmed.2005.06.011.
    Full Text Link to Item
  - Chu, Vivian H., Daniel J. Sexton, Christopher H. Cabell, L Barth Reller, Paul A. Pappas, Rakesh K. Singh, Vance G. Fowler, G Ralph Corey, Olcay Aksoy, and Christopher W. Woods. “Repeat infective endocarditis: differentiating relapse from reinfection..” Clin Infect Dis 41, no. 3 (August 1, 2005): 406–9. https://doi.org/10.1086/431590.
    Full Text Link to Item
  - Shah, Pramod M. “Classification of community-acquired endocarditis due to coagulase-negative staphylococci..” Clin Infect Dis 40, no. 11 (June 1, 2005). https://doi.org/10.1086/430174.
    Full Text Link to Item
  - Stryjewski, Martin E., William D. O’Riordan, William K. Lau, Francis D. Pien, Lala M. Dunbar, Marc Vallee, Vance G. Fowler, et al. “Telavancin versus standard therapy for treatment of complicated skin and soft-tissue infections due to gram-positive bacteria..” Clin Infect Dis 40, no. 11 (June 1, 2005): 1601–7. https://doi.org/10.1086/429914.
    Full Text Link to Item
  - El-Ahdab, Fadi, Daniel Kelly Benjamin, Andrew Wang, Christopher H. Cabell, Vivian H. Chu, Martin E. Stryjewski, G Ralph Corey, Daniel J. Sexton, L Barth Reller, and Vance G. Fowler. “Risk of endocarditis among patients with prosthetic valves and Staphylococcus aureus bacteremia..” Am J Med 118, no. 3 (March 2005): 225–29. https://doi.org/10.1016/j.amjmed.2004.12.017.
    Full Text Link to Item
  - Chu, Vivian H., Christopher H. Cabell, Elias Abrutyn, G Ralph Corey, Bruno Hoen, Jose M. Miro, Lars Olaison, et al. “Native valve endocarditis due to coagulase-negative staphylococci: report of 99 episodes from the International Collaboration on Endocarditis Merged Database..” Clin Infect Dis 39, no. 10 (November 15, 2004): 1527–30. https://doi.org/10.1086/424878.
    Full Text Link to Item
  - Chu, V. H., C. H. Cabell, D. K. Benjamin, E. F. Kuniholm, V. G. Fowler, J. Engemann, D. J. Sexton, G. R. Corey, and A. Wang. “Infective endocarditis: Should diabetic patients be treated more aggressively? Response.” Circulation 110, no. 7 (August 17, 2004): E72–E72.
    Link to Item
  - Stryjewski, Martin E., Vivian H. Chu, Christopher H. Cabell, and Vance G. Fowler. “Issues in the Management of Endocarditis Caused by Resistant Gram-positive Organisms..” Curr Infect Dis Rep 6, no. 4 (August 2004): 283–91. https://doi.org/10.1007/s11908-004-0049-7.
    Full Text Link to Item
  - Chu, Vivian H., Christopher H. Cabell, Daniel K. Benjamin, Erin F. Kuniholm, Vance G. Fowler, John Engemann, Daniel J. Sexton, G Ralph Corey, and Andrew Wang. “Early predictors of in-hospital death in infective endocarditis..” Circulation 109, no. 14 (April 13, 2004): 1745–49. https://doi.org/10.1161/01.CIR.0000124719.61827.7F.
    Full Text Link to Item
  - Cabell, Christopher H., Paul A. Heidenreich, Vivian H. Chu, Christopher M. Moore, Martin E. Stryjewski, G Ralph Corey, and Vance G. Fowler. “Increasing rates of cardiac device infections among Medicare beneficiaries: 1990-1999..” Am Heart J 147, no. 4 (April 2004): 582–86. https://doi.org/10.1016/j.ahj.2003.06.005.
    Full Text Link to Item
- Book Sections
  - Chu, V. H. “HACEK.” In Clinical Infectious Disease, Second Edition, 904–6, 2015. https://doi.org/10.1017/CBO9781139855952.156.
    Full Text
  - Chu, V. H., and D. J. Sexton. “Hacek.” In Clinical Infectious Disease, 965–68, 2010. https://doi.org/10.1017/CBO9780511722240.136.
    Full Text
- Conference Papers
  - Fosbøl, Emil L., Lawrence P. Park, Vivian H. Chu, Eugene Athan, Francois Delahaye, Tomas Freiberger, Cristiane Lamas, et al. “The association between vegetation size and surgical treatment on 6-month mortality in left-sided infective endocarditis..” In Eur Heart J, 40:2243–51, 2019. https://doi.org/10.1093/eurheartj/ehz204.
    Full Text Link to Item
  - Hannan, M. M., R. Xie, J. A. Cowger, S. Schueler, Tm De By, A. I. Dipchand, V. H. Chu, et al. “The Epidemiology of Infection in MCS from the IMACS Database: January 2013 to December 2015.” In Journal of Heart and Lung Transplantation, 36:S27–S27. ELSEVIER SCIENCE INC, 2017.
    Link to Item
  - Delahaye, F., V. H. Chu, B. Hoen, C. A. Mestres, P. Pappas, M. Santos, and A. Wang. “Association between type of valve prosthesis and one year mortality in IE: an analysis of 1467 patients from the International collaboration on endocarditis prospective cohort study.” In European Heart Journal, 34:861–62. OXFORD UNIV PRESS, 2013.
    Link to Item
  - Athan, E., V. H. Chu, P. Tattevin, C. Selton-Suty, P. Jones, C. Naber, J. M. Miró, et al. “SY.3.1 CLINICAL CHARACTERISTICS AND OUTCOME OF INFECTIVE ENDOCARDITIS INVOLVING IMPLANTABLE CARDIAC DEVICES.” In International Journal of Antimicrobial Agents, 41:S3–S3. Elsevier BV, 2013. https://doi.org/10.1016/s0924-8579(13)70010-4.
    Full Text
  - Barsic, B., V. H. Chu, V. Krajinovic, I. Rudez, D. Raffanelli, J. Vincelj, and A. Wang. “THE IMPACT OF VALVE SURGERY ON MORTALITY IN INFECTIVE ENDOCARDITIS COMPLICATED WITH EMBOLIC STROKE: A PROPENSITY SCORE ANALYSIS.” In International Journal of Antimicrobial Agents, 41:S29–S29. ELSEVIER SCIENCE BV, 2013.
    Link to Item
  - Barsic, B., V. H. Chu, V. Krajinovic, I. Rudez, D. Raffanelli, J. Vincelj, and G. R. Corey. “OUTCOME OF EARLY VALVE SURGERY COMPARED TO MEDICAL TREATMENT IN INFECTIVE ENDOCARDITIS COMPLICATED WITH EMBOLIC STROKE.” In International Journal of Antimicrobial Agents, 41:S29–S29. ELSEVIER SCIENCE BV, 2013.
    Link to Item
  - Dayer, M., M. H. Thornhill, J. M. Forde, G. R. Corey, V. H. Chu, D. J. Couper, and P. B. Lockhart. “No significant increase in the incidence of infective endocarditis following the cessation of antibiotic prophylaxis for dental procedures.” In European Heart Journal, 31:467–467. OXFORD UNIV PRESS, 2010.
    Link to Item
  - Chu, V. H., H. Cabell, J. Y. Friedman, S. D. Reed, R. I. Griffiths, K. S. Kaye, D. R. Crosslin, et al. “The clinical and economic impact of Staphylococcus aureus bacteremia in patients with cardiovascular devices.” In Circulation, 110:566–566. LIPPINCOTT WILLIAMS & WILKINS, 2004.
    Link to Item
Teaching & Mentoring
Recent Courses
- CRSP 301B: Research in Clinical Research 2020
Advising & Mentoring
- Dr. Chu is the co-director of the 3^rd year Duke medical student Clinical Research Study Program (CRSP). This program oversees the clinical research experience of ~10-20 year medical students per year. The program provides mentorship, didactics, and ensures that students actively engage in a specific research project with the goal of a manuscript acceptable for peer-review.
  
  As the Associate Director of Education for Duke’s Clinical and Translational Sciences Award (CTSA) program (U54) 2013 – 2018, Dr. Chu is working to develop educational and career development programs to enhance the success and productivity of clinical/translational researchers.
  
  Dr. Chu is program director of the North Carolina Collaborative Summer Research Experience Program, an 8-week summer program to engage high school students and undergraduates in clinical research and career development in the health sciences. This is funded through the NIH (R25) 2013-2018.
  
  Dr. Chu is also the faculty director for the Duke Clinical Research Undergraduate Experience (dCRUE) which is a weekly dinner lecture series that exposes Duke University undergraduates to clinical and translational research.

Some information on this profile has been compiled automatically from Duke databases and external sources. (Our About page explains how this works.) If you see a problem with the information, please write to Scholars@Duke and let us know. We will reply promptly.

Education, Training, & Certifications

Duke Appointment History

Awards & Honors

Selected Grants

Industry Relationships

Selected Publications

Academic Articles

Book Sections

Conference Papers

Recent Courses

Advising & Mentoring