ConferenceJournal of Clinical Oncology · June 10, 2026
LBA5012Background:
There is a critical evidence gap on the relative benefits and harm ...
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ConferenceJournal of Clinical Oncology · February 20, 2022
243 Background: While intensity-modulated radiotherapy (IMRT) is commonly used to deliver moderately hypofractionated radiotherapy (MHRT) for prostate cancer (PC), IMRT has not been prospectively compared to three-dimensional con ...
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ConferenceInternational journal of radiation oncology, biology, physics · November 2021
Purpose/objective(s)Androgen deprivation therapy (ADT) and radiotherapy (RT) are synergistic, and the combination results in improved survival outcomes for aggressive prostate cancers. However, long-term ADT carries substantial burden of toxicity ...
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ConferencePlos One · April 1, 2021
Purpose The Expanded Prostate Cancer Index Composite (EPIC) is the most commonly used patient reported outcome (PRO) tool in prostate cancer (PC) clinical trials, but health utilities associated with the different health states assessed with this tool are ...
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ConferenceJ Gen Intern Med · January 2021
BACKGROUND: Implementation methods of risk-stratified cancer screening guidance throughout a health care system remains understudied. OBJECTIVE: Conduct a preliminary analysis of the implementation of a risk-stratified prostate cancer screening algorithm i ...
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ConferenceJournal of Clinical Oncology · March 1, 2019
33 Background: Synchronous prostate cancer (PC) and rectosigmoid (RS) cancer (RSC) is a challenging clinical situation. Methods: A retrospective review of Duke University and Durham VA charts was performed for men with adenocarci ...
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ConferenceJournal of Clinical Oncology · March 1, 2019
29 Background: Salvage external beam radiotherapy (RT) and hormonal therapy improves survival over RT alone in men with non-metastatic hormone naïve PC and PSA recurrence after radical prostatectomy (RP). We investigated the safe ...
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ConferenceJournal of Clinical Oncology · February 20, 2018
11 Background: Combined external beam radiotherapy (RT) and androgen deprivation therapy (ADT) improves survival over RT alone for high risk prostate cancer (PC). Long-term ADT use, currently recommended for high risk PC, also in ...
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ConferenceJournal of Clinical Oncology · February 20, 2018
24 Background: The use of radical prostatectomy (RP) as initial treatment of high-risk/locally-advanced prostate cancer is increasing but patients (pts) with adverse pathologic features such as positive surgical margins or T3 dis ...
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ConferenceJournal of Clinical Oncology · February 20, 2017
67 Background: Combined androgen deprivation therapy (ADT) and radiation therapy (RT) is a frequently used localized prostate cancer (PC) treatment. Testosterone recovery (TR) after combined ADT-RT is not well-characterized. We s ...
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ConferenceJ Clin Oncol · October 20, 2016
PURPOSE: We aimed to update a previously published, multi-institutional nomogram of outcomes for salvage radiotherapy (SRT) following radical prostatectomy (RP) for prostate cancer, including patients treated in the contemporary era. METHODS: Individual da ...
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ConferenceProstate Cancer Prostatic Dis · March 2016
BACKGROUND: In men with high Gleason PC and rapid PSA progression after surgery, failure rates remain unacceptably high despite salvage radiation. We explored a novel multimodality approach of docetaxel with anti-angiogenic therapy before salvage radiother ...
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ConferenceJournal of Clinical Oncology · January 10, 2016
1 Background: To determine whether the efficacy of a hypofractionated (H) schedule is no worse than a conventional (C) schedule in men with low-risk prostate cancer. Methods: From April 2006 to December 2009, one thousand one hun ...
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ConferenceJ Palliat Med · November 2015
BACKGROUND: In recent years, palliative treatment of prostate cancer metastases has been characterized by the use of more complex radiation treatment, despite a lack of evidence demonstrating a clinical benefit of these technologies in the palliative setti ...
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ConferenceMed Phys · June 2012
PURPOSE: To evaluate the dosimetric benefits of online image guidance during prostate stereotactic body radiotherapy (SBRT) and the potential on margin reduction. METHODS: 28 prostate SBRT patients were retrospectively studied, each treated with 37Gy in 5 ...
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ConferenceMedical Physics · January 1, 2009
Purpose: To develop quality‐assurance (QA) protocols for the Calypso® 4D Localization System including acceptance testing, commissioning, daily QA, monthly QA, and annual QA. Method and Materials: The following acceptance testing/commissioning/QA protocols ...
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ConferenceMedical Physics · January 1, 2009
Purpose: The purpose of this report is to compare RapidArc plans and conventional IMRT plans for prostate cancer involving seminal vesicles. Methods and Materials: This study included 10 patients. The planning‐target volume (PTV) contained the prostate and ...
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ConferenceMedical Physics · January 1, 2008
Purpose: Using an on‐board cone‐beam CT (CBCT) based statistical margin model to determine whether a prostate center‐of‐mass (COM) based translation correction procedure can significantly reduce the CTV‐to‐PTV margin required for prostate patients who were ...
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ConferenceMedical Physics · January 1, 2008
Purpose: To investigate the feasibility of a novel online IMRT re‐optimization process. This online process can be an integral part to the current prostate IGRT paradigm to augment the existing patient alignment techniques for cases with complex daily orga ...
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ConferenceMedical Physics · January 1, 2008
Purpose: Accurate and reliable post‐prostate implant dosimetric analysis requires optimal identification of the seeds on CT and optimal description of soft tissues on MRI. We present a fast seed localization technique for MRI that is also robust from motio ...
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ConferenceMedical Physics · January 1, 2008
Purpose: This study proposes a novel on‐line IGRT technique that can modify the original IMRT plan to match with the “anatomy‐of‐the‐day” within few minutes. The performance of this technique is compared with current on‐line IGRT strategies using bone/soft ...
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ConferenceMedical Physics · January 1, 2007
PURPOSES: There is a growing interest using MRI only for prostate cancer treatment planning. This study is aimed to investigate clinical feasibility of matching 3D planning MRI to on‐board cone‐beam CT (CBCT) images for target localization. Materials and M ...
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ConferenceMedical Physics · January 1, 2007
Purpose: To evaluate the dosimetric improvement of IMRT treatment plans generated with patient‐specific margins compared to uniform margins for prostate cancer patients. Methods and Materials: For 13 prostate cancer patients who underwent IMRT treatment, d ...
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