Scholars@Duke
Walter T Lee

Walter T Lee

Professor of Head and Neck Surgery & Communication Sciences
Head & Neck Surgical Oncology
walter.lee@duke.edu
Duke South Yellow Zone 4000, DUMC Box 3805, Durham, NC 27710
40 Medicine Circle, DUMC Box 3805, Durham, NC 27710

Scholarly Works - Conferences

Spikey nanorattle-based SERS biosensors for direct detection of cancer-associated mRNA

Conference Progress in Biomedical Optics and Imaging Proceedings of SPIE · March 6, 2026 Head and neck squamous cell carcinoma (HNSCC) remains one of the most common and lethal malignancies worldwide, originating mucosal epithelium of the oral cavity, pharynx, and larynx. [1]. Patient survival is strongly dependent on early diagnosis. In many ... Full text Cite

Direct SERS Detection of mRNA Cancer Biomarkers Using Spikey Nanorattle Biosensors

Conference Progress in Biomedical Optics and Imaging Proceedings of SPIE · January 1, 2026 Head and neck squamous cell carcinoma (HNSCC) remains one of the most common and lethal malignancies worldwide, originating mucosal epithelium of the oral cavity, pharynx, and larynx. [1]. Patient survival is strongly dependent on early diagnosis. In many ... Full text Cite

AI-Assisted Triage and Decision Support of Head and Neck Cancer Screening and Diagnosis in Low-Resourced Settings

Conference Ijcai International Joint Conference on Artificial Intelligence · January 1, 2025 The mortality burden of head and neck cancer (HNC) is increasing globally and disproportionately affects people in low-and middle-income countries with limited medical workforce. To address this issue, artificial intelligence (AI) algorithms are increasing ... Full text Cite

Abstract PR004: Differential gene expression analysis comparing Black and White patients with HPV-positive oropharyngeal squamous cell carcinoma reveals suppressed immune response and higher rates P16/HPV DNA discordance in Black patients

Conference Cancer Epidemiology, Biomarkers & Prevention · September 21, 2024 AbstractBackground-Human papilloma virus (HPV-positive (+)) oropharynx cancer (OPC) are a distinct neoplastic entity associated with a significant survival advantage compared to HPV- OPCs. The survival advan ... Full text Cite

Value Signposts in MedTech Development: An Experience from the Field

Conference Ifmbe Proceedings · January 1, 2020 Medical technology (MedTech) is traditionally seen as enabling the delivery of health in a better, innovative fashion. For example, the Da Vinci robot enables robotic surgeries, and Ardian enables surgical treatment of refractory hypertension. More recentl ... Full text Cite

Establishing a Healthcare Research Network in Vietnam: A Platform for Collaborative Quality Improvement

Conference Ifmbe Proceedings · January 1, 2020 There is both a demand and need for delivering patient centered care in health systems. This is especially challenging in developing countries in which resources are limited, population health burdens are extensive, and coordination between facilities is f ... Full text Cite

A nanophotonic-based assay for point-of-care medical diagnostics of malaria in low and middle income countries

Conference Progress in Biomedical Optics and Imaging Proceedings of SPIE · January 1, 2019 Direct detection of genetic biomarkers in tissue and body fluids without complex target extraction and amplification processes can revolutionize nucleic acid-based diagnostics by enabling the use of this technology at the point-of-care. The development of ... Full text Cite

Upper Airway Surgery in Patients with Sleep Apnea.

Conference Otolaryngol Head Neck Surg · August 2012 Objective: 1) Evaluate the safety of outpatient and overnight observation of sleep apnea surgery patients using new preoperative screening criteria. 2) Compare the cost-effectiveness of outpatient and overnight observational sleep apnea surgery compared to ... Full text Link to item Cite

Systematic review of 99mTc human serum albumin and 99mTc sulfur colloid studies of sentinel lymph node biopsy of cutaneous melanoma of the head and neck

Conference Laryngoscope · July 11, 2011 Introduction: Sentinel lymph node biopsy (SLNB) of head and neck melanoma presents a technical challenge due to the multiplicity of basins and variable lymph node drainage. Radiotracer size and particulate nature determines speed of lymphatic drainage into ... Full text Cite