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Philip John Walther

Professor of Urology
Urology
Box 3314 Med Ctr, Durham, NC 27710
3907 Saint Marks Rd, Durham, NC 27707

Featured Works


Glucocorticoids manifest androgenic activity in a cell line derived from a metastatic prostate cancer.

Journal article Cancer Res · December 15, 2001 Featured Work The pathophysiological mechanism(s) by which androgen independence develops in prostate cancer remains to be determined. The identification in many prostate cancer specimens of a mutant androgen receptor, T877A, with altered ligand specificity has provided ... Link to item Cite

Pilot study of dietary fat restriction and flaxseed supplementation in men with prostate cancer before surgery: exploring the effects on hormonal levels, prostate-specific antigen, and histopathologic features.

Journal article Urology · July 2001 Featured Work OBJECTIVES: Dietary fat and fiber affect hormonal levels and may influence cancer progression. Flaxseed is a rich source of lignan and omega-3 fatty acids and may thwart prostate cancer. The potential effects of flaxseed may be enhanced with concomitant fa ... Full text Link to item Cite

Contemporary chemotherapeutic approaches for the treatment of hormone-refractory prostate carcinoma.

Journal article World J Urol · June 2000 Featured Work The medical management of hormone-refractory prostate cancer remains difficult and largely palliative. The development of effective antineoplastic agents has been frustrated by difficulty in the establishment of satisfactory objective response criteria for ... Full text Link to item Cite

Time for a neoadjuvant chemotherapy strategy in prostate cancer?

Journal article Curr Opin Urol · May 2000 Featured Work Full text Link to item Cite

Early onset baldness and prostate cancer risk.

Journal article Cancer Epidemiol Biomarkers Prev · March 2000 Featured Work Prostatic carcinoma is the leading cancer among American men, yet few risk factors have been established. Although increased androgen levels have long been associated with both prostatic carcinoma and baldness, to date no studies have shown an association ... Link to item Cite