Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Vascular Neurology Fellowship, Neurology, Beth Israel Deaconess Medical Center 2010 - 2011
  • Residency, Neurology, Medical University of South Carolina, College of Medicine 2006 - 2010
  • M.D., Central South University, Xiangya School of Medicine (China) 1996
• 

  Previous Appointments & Affiliations

  • Instructor in the Department of Neurology, Neurology, Stroke and Vascular Neurology, Neurology 2019
• Recognition
• 

  Awards & Honors

  • Franz Gerstenbrand Award. World Federation of Neuorehabilitation. 2011
  • Stroke Rehabilitation Award. American Heart Association. 2010
• Expertise
• 

  Subject Headings

  • Stroke
  • Stroke Rehabilitation
• Research
• 

  Selected Grants

  • Cardioembolism as a Mechanism of Central Retinal Artery Occlusion awarded by National Institutes of Health 2022 - 2027
  • Validation of Early Prognostic Data for Recovery Outcomes after Stroke for Future, Higher Yield Trials (VERIFY) awarded by University of Cincinnati 2021 - 2026
  • 3D Functional Photoacoustic Imaging of Human Brain with a Stretchable Ultrasound Matrix Array awarded by Pennsylvania State University 2021 - 2023
  • TRANScranial direct current stimulation for POst-stroke motor Recover - a phase II sTudy (TRANSPORT 2) awarded by University of Cincinnati 2019 - 2023
  • TRANScranial direct current stimulation for POst-stroke motor Recover - a phase II sTudy (TRANSPORT 2) awarded by National Institutes of Health 2019 - 2023
  • Virtual Activities of Living for Occupational Rehabilitation (VALOR) awarded by Barron Associates 2022 - 2023
  • Optimizing Parameters of Low-Intensity Focused Ultrasound for Cortical Modulation in Stroke Patients awarded by  American Heart Association 2021 - 2022
  • Realistic Measurements of tDCS-Modulated Activity and Electric Fields in the Human Brain In Vivo awarded by National Institutes of Health 2019 - 2022
• 

  External Relationships

  • AHA ( American heart association)
  • Huamed Inc
  • Ipsen
  • National Institutes of Health
  • Precision Neuroscience Inc
  • rehabilitation care consortium
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Feng, Wuwei, Alexis Domeracki, Christine Park, Shreyansh Shah, Pratik Y. Chhatbar, Swaroop Pawar, Cherylee Chang, et al. “Revisiting Transcranial Light Stimulation as a Stroke Therapeutic-Hurdles and Opportunities.” Transl Stroke Res, November 12, 2022. https://doi.org/10.1007/s12975-022-01103-7.
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    • Dawson, Jesse, Navzer D. Engineer, Steven C. Cramer, Steven L. Wolf, Rushna Ali, Michael W. O’Dell, David Pierce, et al. “Vagus Nerve Stimulation Paired With Rehabilitation for Upper Limb Motor Impairment and Function After Chronic Ischemic Stroke: Subgroup Analysis of the Randomized, Blinded, Pivotal, VNS-REHAB Device Trial.” Neurorehabil Neural Repair, October 13, 2022, 15459683221129274. https://doi.org/10.1177/15459683221129274.
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    • Keser, Zafer, and Wuwei Feng. “Vagus Nerve Stimulation for Stroke Motor Recovery-What Is Next?” Transl Stroke Res, June 2, 2022. https://doi.org/10.1007/s12975-022-01041-4.
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    • Zavaliangos-Petropulu, Artemis, Bethany Lo, Miranda R. Donnelly, Nicolas Schweighofer, Keith Lohse, Neda Jahanshad, Giuseppe Barisano, et al. “Chronic Stroke Sensorimotor Impairment Is Related to Smaller Hippocampal Volumes: An ENIGMA Analysis.” J Am Heart Assoc 11, no. 10 (May 17, 2022): e025109. https://doi.org/10.1161/JAHA.121.025109.
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    • Mac Grory, Brian, Jonathan P. Piccini, Shadi Yaghi, Sven Poli, Adam De Havenon, Sara K. Rostanski, Martin Weiss, Ying Xian, S Claiborne Johnston, and Wuwei Feng. “Hyperglycemia, Risk of Subsequent Stroke, and Efficacy of Dual Antiplatelet Therapy: A Post Hoc Analysis of the POINT Trial.” J Am Heart Assoc 11, no. 3 (February 2022): e023223. https://doi.org/10.1161/JAHA.121.023223.
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    • Wang, Minmin, Jiawei Han, Hongjie Jiang, Junming Zhu, Wuwei Feng, Pratik Y. Chhatbar, Jianmin Zhang, and Shaomin Zhang. “Intracranial Electric Field Recording During Multichannel Transcranial Electrical Stimulation,” December 21, 2021. https://doi.org/10.1101/2021.12.19.473336.
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    • Hong, Zhongqiu, Haiqing Zheng, Jing Luo, Mingyu Yin, Yinan Ai, Baomei Deng, Wuwei Feng, and Xiquan Hu. “Effects of Low-Frequency Repetitive Transcranial Magnetic Stimulation on Language Recovery in Poststroke Survivors With Aphasia: An Updated Meta-analysis.” Neurorehabil Neural Repair 35, no. 8 (August 2021): 680–91. https://doi.org/10.1177/15459683211011230.
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    • Mac Grory, Brian, Sean R. Landman, Paul D. Ziegler, Chantal J. Boisvert, Shane P. Flood, Christoph Stretz, Tracy E. Madsen, et al. “Detection of Atrial Fibrillation After Central Retinal Artery Occlusion.” Stroke 52, no. 9 (August 2021): 2773–81. https://doi.org/10.1161/STROKEAHA.120.033934.
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    • Mac Grory, Brian, Matthew Schrag, Sven Poli, Chantal J. Boisvert, Martin S. Spitzer, Maximillian Schultheiss, Max Nedelmann, et al. “Structural and Functional Imaging of the Retina in Central Retinal Artery Occlusion - Current Approaches and Future Directions.” J Stroke Cerebrovasc Dis 30, no. 7 (July 2021): 105828. https://doi.org/10.1016/j.jstrokecerebrovasdis.2021.105828.
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    • Mac Grory, Brian, Ian J. Saldanha, Eva A. Mistry, Christoph Stretz, Sven Poli, Marek Sykora, Lars Kellert, et al. “Thrombolytic therapy for wake-up stroke: A systematic review and meta-analysis.” Eur J Neurol 28, no. 6 (June 2021): 2006–16. https://doi.org/10.1111/ene.14839.
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    • Dawson, Jesse, Charles Y. Liu, Gerard E. Francisco, Steven C. Cramer, Steven L. Wolf, Anand Dixit, Jen Alexander, et al. “Vagus nerve stimulation paired with rehabilitation for upper limb motor function after ischaemic stroke (VNS-REHAB): a randomised, blinded, pivotal, device trial.” Lancet 397, no. 10284 (April 24, 2021): 1545–53. https://doi.org/10.1016/S0140-6736(21)00475-X.
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    • Wu, Yiqun, Fei Chen, Haiqing Song, Wuwei Feng, Jinping Sun, Ruisen Liu, Dongmei Li, and Ying Liu. “Use of a Smartphone Platform to Help With Emergency Management of Acute Ischemic Stroke: Observational Study.” Jmir Mhealth Uhealth 9, no. 2 (February 9, 2021): e25488. https://doi.org/10.2196/25488.
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    • Inamullah, Ovais, Yuting P. Chiang, Muath Bishawi, Martin Weiss, Michael W. Lutz, Laura J. Blue, Wayne Feng, Carmelo A. Milano, Matthew Luedke, and Nada El Husseini. “Characteristics of strokes associated with centrifugal flow left ventricular assist devices.” Sci Rep 11, no. 1 (January 18, 2021): 1645. https://doi.org/10.1038/s41598-021-81445-8.
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    • Nam, Chang S., Zachary Traylor, Mengyue Chen, Xiaoning Jiang, Wuwei Feng, and Pratik Yashvant Chhatbar. “Direct Communication Between Brains: A Systematic PRISMA Review of Brain-To-Brain Interface.” Front Neurorobot 15 (2021): 656943. https://doi.org/10.3389/fnbot.2021.656943.
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    • Humayun, Lucas, Colin Smith, Wanlu Li, Yu Shrike Zhang, Christine Park, Wuwei Feng, and Junjie Yao. “SARS-CoV-2-related vascular injury: mechanisms, imaging and models.” Microphysiol Syst 5 (January 2021). https://doi.org/10.21037/mps-20-6.
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    • Kim, Taewon, Christine Park, Pratik Y. Chhatbar, Jody Feld, Brian Mac Grory, Chang S. Nam, Pu Wang, Mengyue Chen, Xiaoning Jiang, and Wuwei Feng. “Effect of Low Intensity Transcranial Ultrasound Stimulation on Neuromodulation in Animals and Humans: An Updated Systematic Review.” Front Neurosci 15 (2021): 620863. https://doi.org/10.3389/fnins.2021.620863.
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    • Mattke, Soeren, Steven C. Cramer, Mo Wang, Janet Prvu Bettger, Kevin M. Cockroft, Wuwei Feng, Michael Jaffee, et al. “Estimating minimal clinically important differences for two scales in patients with chronic traumatic brain injury.” Curr Med Res Opin 36, no. 12 (December 2020): 1999–2007. https://doi.org/10.1080/03007995.2020.1841616.
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    • Wu, Yiqun, Fei Chen, Haiqing Song, Wuwei Feng, Jinping Sun, Ruisen Liu, Dongmei Li, and Ying Liu. “Use of a Smartphone Platform to Help With Emergency Management of Acute Ischemic Stroke: Observational Study (Preprint),” November 4, 2020. https://doi.org/10.2196/preprints.25488.
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    • Khan, Mushfiquddin, Pavan Kumar, Fei Qiao, SM Touhidul Islam, Avtar K. Singh, Je-Seong Won, Wayne Feng, and Inderjit Singh. “Targeting GSNOR for functional recovery in a middle-aged mouse model of stroke.” Brain Res 1741 (August 15, 2020): 146879. https://doi.org/10.1016/j.brainres.2020.146879.
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    • Broderick, Joseph P., Jordan J. Elm, L Scott Janis, Wenle Zhao, Claudia S. Moy, Catherine R. Dillon, Marc I. Chimowitz, et al. “National Institutes of Health StrokeNet During the Time of COVID-19 and Beyond.” Stroke 51, no. 8 (August 2020): 2580–86. https://doi.org/10.1161/STROKEAHA.120.030417.
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    • Zhang, Liying, Xiaofeng Yang, Mingyu Yin, Huaichun Yang, Lili Li, Alexandra Parashos, Ali Alawieh, Wuwei Feng, Haiqing Zheng, and Xiquan Hu. “An Animal Trial on the Optimal Time and Intensity of Exercise after Stroke.” Med Sci Sports Exerc 52, no. 8 (August 2020): 1699–1709. https://doi.org/10.1249/MSS.0000000000002318.
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    • Yao, Xiaoling, Lijun Cui, Jixian Wang, Wuwei Feng, Yong Bao, and Qing Xie. “Effects of transcranial direct current stimulation with virtual reality on upper limb function in patients with ischemic stroke: a randomized controlled trial.” J Neuroeng Rehabil 17, no. 1 (June 15, 2020): 73. https://doi.org/10.1186/s12984-020-00699-x.
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    • Liu, Shimeng, Haiqing Zheng, Wengui Yu, Viswanathan Ramakrishnan, Shreyansh Shah, Louis Fernando Gonzalez, Inderjit Singh, Carmelo Graffagnino, and Wuwei Feng. “Investigation of S-Nitrosoglutathione in stroke: A systematic review and meta-analysis of literature in pre-clinical and clinical research.” Exp Neurol 328 (June 2020): 113262. https://doi.org/10.1016/j.expneurol.2020.113262.
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    • Alawieh, Ali M., E Farris Langley, Wuwei Feng, Alejandro M. Spiotta, and Stephen Tomlinson. “Complement-Dependent Synaptic Uptake and Cognitive Decline after Stroke and Reperfusion Therapy.” J Neurosci 40, no. 20 (May 13, 2020): 4042–58. https://doi.org/10.1523/JNEUROSCI.2462-19.2020.
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    • Weiss, Martin, Shreyansh Shah, and Wuwei Feng. “Letter by Weiss et al Regarding Article, "1/2SH: A Simple, Accurate, and Reliable Method of Calculating the Hematoma Volume of Spontaneous Intracerebral Hemorrhage".” Stroke 51, no. 5 (May 2020): e90. https://doi.org/10.1161/STROKEAHA.120.029300.
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    • Seo, Na Jin, Leah R. Enders, Andrew Fortune, Shannon Cain, Amanda A. Vatinno, Eli Schuster, Viswanathan Ramakrishnan, and Wuwei Feng. “Phase I Safety Trial: Extended Daily Peripheral Sensory Stimulation Using a Wrist-Worn Vibrator in Stroke Survivors.” Transl Stroke Res 11, no. 2 (April 2020): 204–13. https://doi.org/10.1007/s12975-019-00724-9.
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    • Wu, Yiqun, Fei Chen, Zijing Wang, Wuwei Feng, Ying Liu, Yuping Wang, and Haiqing Song. “Reductions in Hospital Admissions and Delays in Acute Stroke Care During the Pandemic of COVID-19.” Front Neurol 11 (2020): 584734. https://doi.org/10.3389/fneur.2020.584734.
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    • Alawieh, Ali, L. Fernando Gonzalez, and Wuwei Feng. “Barriers and opportunities of cortical stimulation via cerebral venous approach.” Brain Stimul 13, no. 2 (2020): 401–2. https://doi.org/10.1016/j.brs.2019.11.011.
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    • Shah, Shreyansh, Li Liang, Andrzej Kosinski, Adrian F. Hernandez, Lee H. Schwamm, Eric E. Smith, Gregg C. Fonarow, et al. “Safety and Outcomes of Intravenous tPA in Acute Ischemic Stroke Patients With Prior Stroke Within 3 Months: Findings From Get With The Guidelines-Stroke.” Circ Cardiovasc Qual Outcomes 13, no. 1 (January 2020): e006031. https://doi.org/10.1161/CIRCOUTCOMES.119.006031.
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    • Shah, Shreyansh, Pratik Y. Chhatbar, Jody A. Feld, and Wuwei Feng. “Integrating tDCS into routine inpatient rehabilitation practice to boost post-stroke recovery.” Brain Stimul 13, no. 4 (2020): 953–54. https://doi.org/10.1016/j.brs.2020.04.002.
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    • Girotra, Tarun, and Wuwei Feng. “Effects of antiplatelet therapy after stroke due to intracerebral haemorrhage (RESTART): are neurologists feeling more comfortable to RESTART antiplatelet?” Ann Transl Med 7, no. Suppl 6 (September 2019): S214. https://doi.org/10.21037/atm.2019.08.84.
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    • Smith, Colin, Eyad Almallouhi, and Wuwei Feng. “Urinary tract infection after stroke: A narrative review.” J Neurol Sci 403 (August 15, 2019): 146–52. https://doi.org/10.1016/j.jns.2019.06.005.
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    • Zheng, Haiqing, Bin Zhang, Pratik Y. Chhatbar, Yi Dong, Ali Alawieh, Forrest Lowe, Xiquan Hu, and Wuwei Feng. “Mesenchymal Stem Cell Therapy in Stroke: A Systematic Review of Literature in Pre-Clinical and Clinical Research.” Cell Transplant 27, no. 12 (December 2018): 1723–30. https://doi.org/10.1177/0963689718806846.
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    • Feng, Wuwei, Steven A. Kautz, Gottfried Schlaug, Caitlyn Meinzer, Mark S. George, and Pratik Y. Chhatbar. “Transcranial Direct Current Stimulation for Poststroke Motor Recovery: Challenges and Opportunities.” Pm R 10, no. 9 Suppl 2 (September 2018): S157–64. https://doi.org/10.1016/j.pmrj.2018.04.012.
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    • Dong, Yi, Kun Fang, Xin Wang, Shengdi Chen, Xueyuan Liu, Yuwu Zhao, Yangtai Guan, et al. “The network of Shanghai Stroke Service System (4S): A public health-care web-based database using automatic extraction of electronic medical records.” Int J Stroke 13, no. 5 (July 2018): 539–44. https://doi.org/10.1177/1747493018765492.
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    • Chhatbar, Pratik Y., Steven A. Kautz, Istvan Takacs, Nathan C. Rowland, Gonzalo J. Revuelta, Mark S. George, Marom Bikson, and Wuwei Feng. “Evidence of transcranial direct current stimulation-generated electric fields at subthalamic level in human brain in vivo.” Brain Stimul 11, no. 4 (2018): 727–33. https://doi.org/10.1016/j.brs.2018.03.006.
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    • Chhatbar, Pratik Y., Mark S. George, Steven A. Kautz, and Wuwei Feng. “Charge density, not current density, is a more comprehensive safety measure of transcranial direct current stimulation.” Brain Behav Immun 66 (November 2017): 414–15. https://doi.org/10.1016/j.bbi.2017.08.008.
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    • Liu, Shimeng, Wuwei Feng, Pratik Y. Chhatbar, Yumei Liu, Xunming Ji, and Bruce Ovbiagele. “Mobile health as a viable strategy to enhance stroke risk factor control: A systematic review and meta-analysis.” J Neurol Sci 378 (July 15, 2017): 140–45. https://doi.org/10.1016/j.jns.2017.04.050.
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    • Spampinato, M. V., C. Chan, J. H. Jensen, J. A. Helpern, L. Bonilha, S. A. Kautz, P. J. Nietert, and W. Feng. “Diffusional Kurtosis Imaging and Motor Outcome in Acute Ischemic Stroke.” Ajnr Am J Neuroradiol 38, no. 7 (July 2017): 1328–34. https://doi.org/10.3174/ajnr.A5180.
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    • Chhatbar, Pratik Y., Mark S. George, Steven A. Kautz, and Wuwei Feng. “Quantitative reassessment of safety limits of tDCS for two animal studies.” Brain Stimul 10, no. 5 (2017): 1011–12. https://doi.org/10.1016/j.brs.2017.07.008.
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    • Chhatbar, Pratik Y., Rong Chen, Rachael Deardorff, Blair Dellenbach, Steven A. Kautz, Mark S. George, and Wuwei Feng. “Safety and tolerability of transcranial direct current stimulation to stroke patients - A phase I current escalation study.” Brain Stimul 10, no. 3 (2017): 553–59. https://doi.org/10.1016/j.brs.2017.02.007.
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    • Owolabi, Mayowa, Paul Olowoyo, J Jaime Miranda, Rufus Akinyemi, Wuwei Feng, Joseph Yaria, Tomiwa Makanjuola, et al. “Gaps in Hypertension Guidelines in Low- and Middle-Income Versus High-Income Countries: A Systematic Review.” Hypertension 68, no. 6 (December 2016): 1328–37. https://doi.org/10.1161/HYPERTENSIONAHA.116.08290.
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    • Chhatbar, Pratik Y., James R. Sawers, and Wuwei Feng. “Response to the Response to "Does tDCS Actually Deliver DC Stimulation?".” Brain Stimul 9, no. 6 (2016): 952–54. https://doi.org/10.1016/j.brs.2016.08.009.
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    • Chhatbar, Pratik Y., James R. Sawers, and Wuwei Feng. “The Proof is in the Pudding: Does tDCS Actually Deliver DC Stimulation?” Brain Stimul 9, no. 4 (2016): 625–26. https://doi.org/10.1016/j.brs.2016.05.002.
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    • Chhatbar, Pratik Y., Viswanathan Ramakrishnan, Steven Kautz, Mark S. George, Robert J. Adams, and Wuwei Feng. “Transcranial Direct Current Stimulation Post-Stroke Upper Extremity Motor Recovery Studies Exhibit a Dose-Response Relationship.” Brain Stimul 9, no. 1 (2016): 16–26. https://doi.org/10.1016/j.brs.2015.09.002.
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    • Feng, Wuwei, Jasmine Wang, Pratik Y. Chhatbar, Christopher Doughty, Douglas Landsittel, Vasileios-Arsenios Lioutas, Steven A. Kautz, and Gottfried Schlaug. “Corticospinal tract lesion load: An imaging biomarker for stroke motor outcomes.” Ann Neurol 78, no. 6 (December 2015): 860–70. https://doi.org/10.1002/ana.24510.
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    • Chhatbar, Pratik Y., and Wuwei Feng. “Data Synthesis in Meta-Analysis may Conclude Differently on Cognitive Effect From Transcranial Direct Current Stimulation.” Brain Stimul 8, no. 5 (2015): 974–76. https://doi.org/10.1016/j.brs.2015.06.001.
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  • Conference Papers

    • Esquenazi, Alberto, Wuwei Wayne Feng, George Wittenberg, Philippe Gallien, Alessio Baricich, Kristina Fanning, Aleksej Zuzek, Gerard Francisco, and Daniel Bandari. “Clinical Characteristics that Impact OnabotulinumtoxinA Treatment Adherence in Patients with Spasticity from the ASPIRE Study.” In Neurology, Vol. 94, 2020.
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    • Liu, Shimeng, Haiqing Zheng, Wengui Yu, Viswanathan Ramakrishnan, Shreyansh Shah, Louis Fernando Gonzalez, Inderjit Singh, Carmelo Graffagnino, and Wuwei Feng. “Investigation of S-Nitrosoglutathione in Stroke: A Systematic Review and Meta-Analysis of Literature in Pre-clinical and Clinical Research.” In Neurology, Vol. 94, 2020.
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    • Feng, Wayne, Pratik Chhatbar, Mark George, Racheal Deardorff, and Steven Kautz. “Safety and Tolerability of Transcranial Direct Current Stimulation to Stroke Patients - A Phase I Current Escalation Study.” In Annals of Neurology, 82:S142–S142. WILEY, 2017.
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    • Feng, Wuwei, Jan A. Enabore, Steve Kautz, Robert J. Adams, and Pratik Chhatbar. “Dose Response Relationship in Transcranial Direct Current Stimulation Stroke Motor Recovery Studies.” In Stroke, Vol. 46. LIPPINCOTT WILLIAMS & WILKINS, 2015.
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    • Folsom, Jamie, Nnadozie Ezerioha, Pratik Chhatbar, Swaroop Pawar, Christina Holmstedt, Edward Jauch, Bruce Ovbiagele, Robert J. Adams, and Wuwei Wayne Feng. “The Impact of Contrast Based CTA/CTP Brain Attack Protocol on Kidney Function.” In Stroke, Vol. 46. LIPPINCOTT WILLIAMS & WILKINS, 2015.
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