Scholars@Duke
William Arthur Jiranek

William Arthur Jiranek

Duke Distinguished Professor of Orthopaedic Surgery
Orthopaedic Surgery
william.jiranek@duke.edu
DUMC Box 104002, Durham, NC 27710
5601 Arringdon Park Drive, Suite 300, Morrisville, NC 27560

Scholarly Works - Conferences

Automatic Kellgren-Lawrence grade estimation driven deep learning algorithms

Conference Progress in Biomedical Optics and Imaging Proceedings of SPIE · January 1, 2020 Knee osteoarthritis (OA) is a prevalent and disabling degenerative joint disease. Objectively identifying knee OA severity is challenging given significant inter-reader variability due to human interpretation factors. The Kellgren-Lawrence (KL) grading sys ... Full text Cite

Automatic estimation of knee joint space narrowing by deep learning segmentation algorithms

Conference Progress in Biomedical Optics and Imaging Proceedings of SPIE · January 1, 2020 Evaluating the severity of knee osteoarthritis (OA) accounts for significant plain film workload and is a crucial component of knee radiograph interpretation, which informs surgical decision-making for costly and invasive procedures such as knee replacemen ... Full text Cite

Inhibition of Methicillin-resistant Staphylococcus aureus-induced cytokines mRNA production in human bone marrow derived mesenchymal stem cells by 1,25-dihydroxyvitamin D3.

Conference BMC Cell Biol · March 25, 2014 BACKGROUND: Methicillin-resistant Staphylococcus aureus (MRSA) is the predominant cause of bone infection. Toll like receptors (TLRs) are an important segments of host response to infection and are expressed by a variety of cells including human mesenchyma ... Full text Link to item Cite

Failure of irrigation and débridement for early postoperative periprosthetic infection.

Conference Clin Orthop Relat Res · January 2013 BACKGROUND: Irrigation and débridement (I&D) of periprosthetic infection (PPI) is associated with infection control ranging from 16% to 47%. Mitigating factors include organism type, host factors, and timing of intervention. While the influence of organism ... Full text Link to item Cite

Save the torn labrum in hips with borderline acetabular coverage.

Conference Clin Orthop Relat Res · December 2012 BACKGROUND: Hip arthroscopy for labral tears improves short-term function, but reoperations occur in 5% to 47% of patients. The effect of borderline acetabular coverage on reoperation rate has been debated. Labral repair rather than débridement has been pr ... Full text Link to item Cite

Does femoral component loosening predispose to femoral fracture?: an in vitro comparison of cemented hips.

Conference Clin Orthop Relat Res · February 2010 The incidence of femur fracture around total hip arthroplasties continues to increase at substantial cost to society. These fractures are frequently associated with a loose femoral component. Consequently, we sought to test whether femoral component loosen ... Full text Link to item Cite

Acetabular liner fixation by cement.

Conference Clin Orthop Relat Res · December 2003 Many situations in revision THA require the exchange of a PE liner in the setting of a well-fixed cementless acetabular shell. Unfortunately, a replacement liner is not always available, the locking mechanism of the metal shell may be damaged or incompatib ... Full text Link to item Cite

Differential messenger ribonucleic acid expression in aggressive versus linear periprosthetic osteolysis.

Conference Clin Orthop Relat Res · July 1998 Osteolysis is a radiographic term used to describe bone resorption adjacent to prosthetic implants. This process involves a spectrum of radiographic presentations, from small generalized linear patterns (linear osteolysis) to larger erosive patterns (aggre ... Link to item Cite

Mechanical, histological and molecular biological studies on latissimus dorsi muscles conditioned for myocardioplasty

Conference Southern Biomedical Engineering Conference Proceedings · January 1, 1995 Canine latissimus dorsi (LD) muscles were conditioned by electrical stimulation for myocardioplasty study. Changes in maximum force, rate of force development, Phospholamban mRNA (messenger ribonucleic acid) and collagen contents in the conditioned muscles ... Cite