Overview
Survival Analysis
Causal Inference
Design and Analysis of Clinical Trials
Methods for Diagnostic and Predictive Medicine
Analysis of Data from Multiple Sources
Causal Inference
Design and Analysis of Clinical Trials
Methods for Diagnostic and Predictive Medicine
Analysis of Data from Multiple Sources
Current Appointments & Affiliations
Professor of Biostatistics & Bioinformatics
·
2021 - Present
Biostatistics & Bioinformatics, Division of Biostatistics,
Biostatistics & Bioinformatics
Member of the Duke Cancer Institute
·
2015 - Present
Duke Cancer Institute,
Institutes and Centers
Recent Publications
A Powerful and Self-Adaptive Weighted Logrank Test.
Journal Article Stat Med · February 2026 In a weighted logrank test, such as the Harrington-Fleming test and the Tarone-Ware test, predetermined weights are used to emphasize early, middle, or late differences in survival distributions to maximize the test's power. The optimal weight function und ... Full text Link to item CiteChemoradiation ± Atezolizumab in Limited-Stage Small Cell Lung Cancer: Results of NRG Oncology/Alliance LU005.
Journal Article J Clin Oncol · January 13, 2026 PURPOSE: NRG Oncology/Alliance LU005 (ClinicalTrials.gov identifier: NCT03811002) tested the addition of atezolizumab to concurrent chemoradiation (CRT) in this open-label, phase III international trial. METHODS: Patients with limited-stage small cell lung ... Full text Link to item CiteStatistical inference for heterogeneous treatment effect with right-censored data from synthesizing randomized clinical trials and real-world data.
Journal Article Biometrics · October 8, 2025 The heterogeneous treatment effect plays a crucial role in precision medicine. There is evidence that real-world data, even subject to biases, can be employed as supplementary evidence for randomized clinical trials to improve the statistical efficiency of ... Full text Link to item CiteRecent Grants
AFT-61 Stats
ResearchPrincipal Investigator · Awarded by Alliance Foundation Trials, LLC · 2025 - 2030AFT-57 Trials (5d)
ResearchPrincipal Investigator · Awarded by Alliance Foundation Trials, LLC · 2023 - 2028Methods to improve efficiency and robustness of clinical trials using information from real-world data with hidden bias
ResearchPrincipal Investigator · Awarded by Food and Drug Administration · 2023 - 2026View All Grants
Education, Training & Certifications
University of North Carolina, Chapel Hill ·
2003
Ph.D.