Xiaofei Wang
Professor of Biostatistics & Bioinformatics
Design and Analysis of Clinical Trials
Methods for Diagnostic and Predictive Medicine
Survival Analysis
Causal Inference
Analysis of Data from Multiple Sources
Methods for Diagnostic and Predictive Medicine
Survival Analysis
Causal Inference
Analysis of Data from Multiple Sources
Current Appointments & Affiliations
- Professor of Biostatistics & Bioinformatics, Biostatistics & Bioinformatics, Basic Science Departments 2021
- Member of the Duke Cancer Institute, Duke Cancer Institute, Institutes and Centers 2015
Contact Information
- 2424 Erwin Road Suite 1102, 11080 Hock Plaza, Duke Box 272, Durham, NC 27705
- Duke Box 2721, Durham, NC 27710
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xiaofei.wang@duke.edu
(919) 681-5406
- Background
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Education, Training, & Certifications
- Graduate Research Assistant, Biostatistics, University of North Carolina - Chapel Hill 1996 - 2003
- Ph.D., University of North Carolina - Chapel Hill 2003
- Graduate Research Assistant, Computer Sciences, University of North Carolina - Chapel Hill 1994 - 1996
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Previous Appointments & Affiliations
- Professor of Biostatistics and Bioinformatics, Biostatistics & Bioinformatics, Basic Science Departments 2020
- Associate Professor of Biostatistics and Bioinformatics, Biostatistics & Bioinformatics, Basic Science Departments 2012 - 2019
- Assistant Professor of Biostatistics and Bioinformatics, Biostatistics & Bioinformatics, Basic Science Departments 2007 - 2012
- Assistant Research Professor of Biostatistics and Bioinformatics, Biostatistics & Bioinformatics, Basic Science Departments 2004 - 2007
- Instructor, Temporary of Biostatistics and Bioinformatics, Biostatistics & Bioinformatics, Basic Science Departments 2003
- Recognition
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Awards & Honors
- Expertise
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Global Scholarship
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Expertise
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- Research
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Selected Grants
- Anti-PD1 in combination with an inhibitor of PCSK9 to increase MHC class I molecule expression on tumor cells as immunotherapy for NSCLC awarded by Department of Defense 2021 - 2024
- Alliance for Clinical Trials in Oncology awarded by Brigham and Women's Hospital 2019 - 2024
- Alliance NCORP Research Base awarded by Alliance NCTN Foundation 2020 - 2023
- Empower treatment effects evaluation of randomized clinical trials for elderly patients with integrated real-world data awarded by North Carolina State University 2020 - 2023
- Alliance Statistical and Data Management Center - Clinical Trials in Oncology awarded by Mayo Clinic 2019 - 2023
- Alliance Foundation Trials - IT Infrastructure - SOW 9 awarded by Alliance Foundation Trials, LLC 2021 - 2022
- AFT-16 Trials SOW 10 awarded by Alliance Foundation Trials, LLC 2020 - 2022
- AFT-46 Trials SOW 11 awarded by Alliance Foundation Trials, LLC 2020 - 2022
- Cell-Free DNA for Diagnosis of Malignancy, Genetic Mutations and Prognosis in Lung Cancer Related Pleural Effusions awarded by Department of Defense 2020 - 2022
- AFT - 42 Trials 5b awarded by Alliance Foundation Trials, LLC 2020 - 2021
- 2020 Duke - Industry Statistical Symposium (DISS) awarded by Boehringer Ingelheim Pharmaceuticals, Inc. 2020 - 2021
- Alliance Foundation Trials - IT Infrastructure - SOW awarded by Alliance Foundation Trials, LLC 2020
- AFT SOW 3 awarded by Alliance Foundation Trials, LLC 2019 - 2020
- Alliance NCORP Research Base awarded by Mayo Clinic 2014 - 2020
- Administrative Core awarded by University of North Carolina - Chapel Hill 2015 - 2020
- Innovative Biomarker-Integrated Clinical Trial Design and Analysis awarded by University of North Carolina - Chapel Hill 2015 - 2020
- Methods for Discovery and Analysis of Dynamic Treatment Regimes awarded by University of North Carolina - Chapel Hill 2015 - 2020
- Alliance Foundation Trials - IT Infrastructure awarded by Alliance Foundation Trials, LLC 2018 - 2019
- AFT SOW 2 awarded by Alliance Foundation Trials, LLC 2018 - 2019
- Alliance for Clinical Trials in Oncology awarded by Mayo Clinic 2017 - 2019
- Alliance for Clinical Trials in Oncology awarded by Brigham and Women's Hospital 2014 - 2019
- Alliance for Clinical Trials in Oncology awarded by Mayo Clinic 2017 - 2018
- National Clinical Trials Network - Network Group Statistics and DMCs awarded by Mayo Clinic 2014 - 2017
- Translational meta-analysis for elderly lung cancer patients awarded by National Institutes of Health 2013 - 2016
- Cancer and Leukemia Group B Statistical Center awarded by National Institutes of Health 1982 - 2010
- Semiparametric ROC Curve Regression for Cancer Screening Studies awarded by National Institutes of Health 2007 - 2010
- Publications & Artistic Works
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Selected Publications
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Books
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George, Stephen L., Xiaofei Wang, and Herbert Pang. Cancer Clinical Trials Current and Controversial Issues in Design and Analysis. CRC Press, 2016.
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Academic Articles
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Bogart, Jeffrey, Xiaofei Wang, Gregory Masters, Junheng Gao, Ritsuko Komaki, Laurie E. Gaspar, John Heymach, et al. “High-Dose Once-Daily Thoracic Radiotherapy in Limited-Stage Small-Cell Lung Cancer: CALGB 30610 (Alliance)/RTOG 0538.” J Clin Oncol 41, no. 13 (May 1, 2023): 2394–2402. https://doi.org/10.1200/JCO.22.01359.Full Text Link to Item
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Altorki, Nasser, Xiaofei Wang, and Thomas E. Stinchcombe. “Extent of Surgery for Stage IA Non-Small-Cell Lung Cancer. Reply.” N Engl J Med 388, no. 17 (April 27, 2023): 1629–30. https://doi.org/10.1056/NEJMc2302856.Full Text Link to Item
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Yang, Shu, Chenyin Gao, Donglin Zeng, and Xiaofei Wang. “Elastic integrative analysis of randomised trial and real-world data for treatment heterogeneity estimation.” Journal of the Royal Statistical Society Series B: Statistical Methodology, April 6, 2023. https://doi.org/10.1093/jrsssb/qkad017.Full Text
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Villaruz, L. C., X. Wang, E. M. Bertino, L. Gu, S. J. Antonia, T. F. Burns, J. Clarke, et al. “A single-arm, multicenter, phase II trial of osimertinib in patients with epidermal growth factor receptor exon 18 G719X, exon 20 S768I, or exon 21 L861Q mutations.” Esmo Open 8, no. 2 (April 2023): 101183. https://doi.org/10.1016/j.esmoop.2023.101183.Full Text Link to Item
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Altorki, Nasser, Xiaofei Wang, David Kozono, Colleen Watt, Rodney Landrenau, Dennis Wigle, Jeffrey Port, et al. “Lobar or Sublobar Resection for Peripheral Stage IA Non-Small-Cell Lung Cancer.” N Engl J Med 388, no. 6 (February 9, 2023): 489–98. https://doi.org/10.1056/NEJMoa2212083.Full Text Link to Item
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Mahmood, Kamran, Parvathi Jampani, Jeffrey M. Clarke, Steven Wolf, Xiaofei Wang, Momen M. Wahidi, Coral X. Giovacchini, et al. “High Yield of Pleural Cell-Free DNA for Diagnosis of Oncogenic Mutations in Lung Adenocarcinoma.” Chest, January 21, 2023. https://doi.org/10.1016/j.chest.2023.01.019.Full Text Link to Item
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Leung, Tiffany H., James C. Ho, Aya El Helali, Everett E. Vokes, Xiaofei Wang, and Herbert Pang. “New reporting items and recommendations for randomized trials impacted by COVID-19 and force majeure events: a targeted approach.” Ann Transl Med 11, no. 1 (January 15, 2023): 2. https://doi.org/10.21037/atm-22-2160.Full Text Link to Item
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Oswalt, Cameron, Yingzhou Liu, Herbert Pang, Jennifer Le-Rademacher, Xiaofei Wang, and Jeffrey Crawford. “Associations between body mass index, weight loss and overall survival in patients with advanced lung cancer.” J Cachexia Sarcopenia Muscle 13, no. 6 (December 2022): 2650–60. https://doi.org/10.1002/jcsm.13095.Full Text Link to Item
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Yang, Lexie Zidanyue, Qihua He, Jianrong Zhang, Apar Kishor Ganti, Thomas E. Stinchcombe, Herbert Pang, and Xiaofei Wang. “Characteristics of toxicity occurrence patterns in concurrent chemoradiotherapy after induction chemotherapy for patients with locally advanced non-small cell lung cancer: a pooled analysis based on individual patient data of CALGB/Alliance trials.” Transl Cancer Res 11, no. 10 (October 2022): 3506–21. https://doi.org/10.21037/tcr-22-2006.Full Text Link to Item
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Yang, Qing, Amy Zhao, Chiyoung Lee, Xiaofei Wang, Allison Vorderstrasse, and Ruth Q. Wolever. “Latent Profile/Class Analysis Identifying Differentiated Intervention Effects.” Nurs Res 71, no. 5 (September 2022): 394–403. https://doi.org/10.1097/NNR.0000000000000597.Full Text Link to Item
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Schild, Steven E., Xiaofei Wang, Christine M. Bestvina, Terence Williams, Greg Masters, Anurag K. Singh, Thomas E. Stinchcombe, et al. “Alliance A082002 -a randomized phase II/III trial of modern immunotherapy-based systemic therapy with or without SBRT for PD-L1-negative, advanced non-small cell lung cancer.” Clin Lung Cancer 23, no. 5 (July 2022): e317–20. https://doi.org/10.1016/j.cllc.2022.04.004.Full Text Link to Item
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Clarke, Jeffrey M., Lin Gu, Xiaofei F. Wang, Thomas E. Stinchcombe, Marvaretta M. Stevenson, Sundhar Ramalingam, Afreen Shariff, et al. “A Phase 2 Clinical Trial of Combination Nivolumab, Ipilimumab, and Paclitaxel in Patients With Untreated Metastatic NSCLC: The OPTIMAL Trial.” Jto Clin Res Rep 3, no. 6 (June 2022): 100337. https://doi.org/10.1016/j.jtocrr.2022.100337.Full Text Link to Item
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Zhang, Jianrong, Maarten J. IJzerman, Jasmeen Oberoi, Napin Karnchanachari, Rebecca J. Bergin, Fanny Franchini, Paige Druce, Xiaofei Wang, and Jon D. Emery. “Time to diagnosis and treatment of lung cancer: A systematic overview of risk factors, interventions and impact on patient outcomes.” Lung Cancer 166 (April 2022): 27–39. https://doi.org/10.1016/j.lungcan.2022.01.015.Full Text Link to Item
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Jacobs, Corbin D., Kurren Mehta, Junheng Gao, Xiaofei Wang, Joseph K. Salama, Chris R. Kelsey, and Jordan A. Torok. “Nomogram Predicting Overall Survival Benefit of Stereotactic Ablative Radiotherapy for Early-Stage Non-Small Cell Lung Cancer.” Clin Lung Cancer 23, no. 2 (March 2022): 177–84. https://doi.org/10.1016/j.cllc.2021.06.008.Full Text Link to Item
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Pang, Herbert, Guangyu Yang, James C. Ho, Tiffany H. Leung, Qian Shi, Chen Hu, Thomas E. Stinchcombe, and Xiaofei Wang. “Assessing surrogacy using restricted mean survival time ratio for overall survival in non-small cell lung cancer immunotherapy studies.” Chin Clin Oncol 11, no. 1 (February 2022): 7. https://doi.org/10.21037/cco-21-110.Full Text Link to Item
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Tong, Betty C., Lin Gu, Xiaofei Wang, Dennis A. Wigle, Joseph D. Phillips, David H. Harpole, Jacob A. Klapper, Thomas Sporn, Neal E. Ready, and Thomas A. D’Amico. “Perioperative outcomes of pulmonary resection after neoadjuvant pembrolizumab in patients with non-small cell lung cancer.” J Thorac Cardiovasc Surg 163, no. 2 (February 2022): 427–36. https://doi.org/10.1016/j.jtcvs.2021.02.099.Full Text Link to Item
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Stinchcombe, Thomas E., Xiaofei Wang, Robert C. Doebele, Leylah M. Drusbosky, David E. Gerber, Leora Horn, Erin M. Bertino, Geoff Liu, Liza C. Villaruz, and D. Ross Camidge. “Short communication: The activity of brigatinib in patients with disease progression after next generation anaplastic lymphoma tyrosine kinase inhibitors and an exploratory analysis of circulating tumor DNA.” Lung Cancer 165 (January 3, 2022): 43–48. https://doi.org/10.1016/j.lungcan.2021.12.019.Full Text Link to Item
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Isaacs, James, Aaron C. Tan, Brent A. Hanks, Xiaofei Wang, Kouros Owzar, James E. Herndon, Scott J. Antonia, Steven Piantadosi, and Mustafa Khasraw. “Clinical Trials with Biologic Primary Endpoints in Immuno-oncology: Concepts and Usage.” Clin Cancer Res 28, no. 1 (January 1, 2022): 13–22. https://doi.org/10.1158/1078-0432.CCR-21-1593.Full Text Link to Item
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Lee, D., S. Yang, and X. Wang. “Doubly robust estimators for generalizing treatment effects on survival outcomes from randomized controlled trials to a target population.” Journal of Causal Inference 10, no. 1 (January 1, 2022): 415–40. https://doi.org/10.1515/jci-2022-0004.Full Text
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Wahidi, Momen M., Angela Christine Argento, Kamran Mahmood, Scott L. Shofer, Coral Giovacchini, Aaron Pulsipher, Matthew Hartwig, et al. “Comparison of Forceps, Cryoprobe, and Thoracoscopic Lung Biopsy for the Diagnosis of Interstitial Lung Disease - The CHILL Study.” Respiration 101, no. 4 (2022): 394–400. https://doi.org/10.1159/000519674.Full Text Link to Item
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Yang, Shu, and Xiaofei Wang. “RWD-INTEGRATED RANDOMIZED CLINICAL TRIAL ANALYSIS.” Biopharm Rep 29, no. 2 (2022): 15–21.Link to Item
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Lee, Dasom, Shu Yang, Lin Dong, Xiaofei Wang, Donglin Zeng, and Jianwen Cai. “Improving trial generalizability using observational studies.” Biometrics, December 4, 2021. https://doi.org/10.1111/biom.13609.Full Text Link to Item
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Ni, Jianjiao, Yue Zhou, Lin Wu, Xinghao Ai, Xiaorong Dong, Qian Chu, Chengbo Han, Xiaofei Wang, and Zhengfei Zhu. “Sintilimab, stereotactic body radiotherapy and granulocyte-macrophage colony stimulating factor as second-line therapy for advanced non-small cell lung cancer: safety run-in results of a multicenter, single-arm, phase II trial.” Radiat Oncol 16, no. 1 (September 15, 2021): 177. https://doi.org/10.1186/s13014-021-01905-3.Full Text Link to Item
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Hensing, Thomas A., Xiaofei Wang, Thomas E. Stinchcombe, Junheng Gao, Michael V. Knopp, Mark Watson, Arkadiusz Z. Dudek, et al. “Alliance Foundation Trial 09: A Randomized, Multicenter, Phase 2 Trial Evaluating Two Sequences of Pembrolizumab and Standard Platinum-Based Chemotherapy in Patients With Metastatic NSCLC.” Jto Clin Res Rep 2, no. 8 (August 2021): 100208. https://doi.org/10.1016/j.jtocrr.2021.100208.Full Text Link to Item
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Le-Rademacher, Jennifer, and Xiaofei Wang. “Time-To-Event Data: An Overview and Analysis Considerations.” J Thorac Oncol 16, no. 7 (July 2021): 1067–74. https://doi.org/10.1016/j.jtho.2021.04.004.Full Text Link to Item
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Wahidi, Momen M., Kevin Davidson, Scott Shofer, Kamran Mahmood, George Cheng, Coral Giovacchini, Claudia Jones, et al. “Pilot Study of the Performance of 19-G Needle in Endobronchial Ultrasound-guided Transbronchial Aspiration for the Diagnosis and Testing of Molecular Markers in Lung Cancer.” J Bronchology Interv Pulmonol 28, no. 3 (July 1, 2021): 209–14. https://doi.org/10.1097/LBR.0000000000000736.Full Text Link to Item
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Bogart, Jeffrey A., Xiaofei Wang, Gregory A. Masters, Junheng Gao, Ritsuko Komaki, Laurie E. Gaspar, John V. Heymach, et al. “Short Communication: Interim toxicity analysis for patients with limited stage small cell lung cancer (LSCLC) treated on CALGB 30610 (Alliance) / RTOG 0538.” Lung Cancer 156 (June 2021): 68–71. https://doi.org/10.1016/j.lungcan.2021.04.016.Full Text Link to Item
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Tao, Jun, Aminah Jatoi, Jeffrey Crawford, Wendy W. T. Lam, James C. Ho, Xiaofei Wang, and Herbert Pang. “Role of dietary carbohydrates on risk of lung cancer.” Lung Cancer 155 (May 2021): 87–93. https://doi.org/10.1016/j.lungcan.2021.03.009.Full Text Link to Item
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Wang, Xiaofei, Steven Piantadosi, Jennifer Le-Rademacher, and Sumithra J. Mandrekar. “Statistical Considerations for Subgroup Analyses.” J Thorac Oncol 16, no. 3 (March 2021): 375–80. https://doi.org/10.1016/j.jtho.2020.12.008.Full Text Link to Item
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Wong, Melisa L., Junheng Gao, Gita Thanarajasingam, Jeff A. Sloan, Amylou C. Dueck, Paul J. Novotny, Aminah Jatoi, et al. “Expanding Beyond Maximum Grade: Chemotherapy Toxicity over Time by Age and Performance Status in Advanced Non-Small Cell Lung Cancer in CALGB 9730 (Alliance A151729).” Oncologist 26, no. 3 (March 2021): e435–44. https://doi.org/10.1002/onco.13527.Full Text Link to Item
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Stinchcombe, Thomas E., Robert C. Doebele, Xiaofei Wang, David E. Gerber, Leora Horn, and D Ross Camidge. “Preliminary Clinical and Molecular Analysis Results From a Single-Arm Phase 2 Trial of Brigatinib in Patients With Disease Progression After Next-Generation ALK Tyrosine Kinase Inhibitors in Advanced ALK+ NSCLC.” J Thorac Oncol 16, no. 1 (January 2021): 156–61. https://doi.org/10.1016/j.jtho.2020.09.018.Full Text Link to Item
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Le-Rademacher, Jennifer, Camden Lopez, Eric Wolfe, Nathan R. Foster, Sumithra J. Mandrekar, Xiaofei Wang, Rajiv Kumar, Alex Adjei, and Aminah Jatoi. “Weight loss over time and survival: a landmark analysis of 1000+ prospectively treated and monitored lung cancer patients.” J Cachexia Sarcopenia Muscle 11, no. 6 (December 2020): 1501–8. https://doi.org/10.1002/jcsm.12625.Full Text Link to Item
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Bueno, Raphael, William G. Richards, David H. Harpole, Karla V. Ballman, Ming-Sound Tsao, Zhengming Chen, Xiaofei Wang, et al. “Multi-Institutional Prospective Validation of Prognostic mRNA Signatures in Early Stage Squamous Lung Cancer (Alliance).” J Thorac Oncol 15, no. 11 (November 2020): 1748–57. https://doi.org/10.1016/j.jtho.2020.07.005.Full Text Link to Item
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Dudek, Arkadiusz Z., Xiaofei Wang, Lin Gu, Stephanie Duong, Thomas E. Stinchcombe, Robert Kratzke, Hossein Borghaei, Everett E. Vokes, and Hedy L. Kindler. “Randomized Study of Maintenance Pemetrexed Versus Observation for Treatment of Malignant Pleural Mesothelioma: CALGB 30901.” Clin Lung Cancer 21, no. 6 (November 2020): 553-561.e1. https://doi.org/10.1016/j.cllc.2020.06.025.Full Text Link to Item
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Wang, Ting, Xiaofei Wang, Stephen L. George, and Haibo Zhou. “Design and analysis of biomarker-integrated clinical trials with adaptive threshold detection and flexible patient enrichment.” J Biopharm Stat 30, no. 6 (November 1, 2020): 1060–76. https://doi.org/10.1080/10543406.2020.1832110.Full Text Link to Item
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Wang, Fan, Richard L. Schilsky, David Page, Robert M. Califf, Kei Cheung, Xiaofei Wang, and Herbert Pang. “Development and Validation of a Natural Language Processing Tool to Generate the CONSORT Reporting Checklist for Randomized Clinical Trials.” Jama Netw Open 3, no. 10 (October 1, 2020): e2014661. https://doi.org/10.1001/jamanetworkopen.2020.14661.Full Text Link to Item
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Yan, Kang K., Xiaofei Wang, Wendy W. T. Lam, Varut Vardhanabhuti, Anne W. M. Lee, and Herbert H. Pang. “Radiomics analysis using stability selection supervised component analysis for right-censored survival data.” Comput Biol Med 124 (September 2020): 103959. https://doi.org/10.1016/j.compbiomed.2020.103959.Full Text Link to Item
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Wu, Yuan, Xiaofei Wang, Jiaxing Lin, Beilin Jia, and Kouros Owzar. “Predictive accuracy of markers or risk scores for interval censored survival data.” Stat Med 39, no. 18 (August 15, 2020): 2437–46. https://doi.org/10.1002/sim.8547.Full Text Link to Item
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Zhang, Jianrong, Meagan R. Pilar, Xiaofei Wang, Jingxia Liu, Herbert Pang, Ross C. Brownson, Graham A. Colditz, Wenhua Liang, and Jianxing He. “Endpoint surrogacy in oncology Phase 3 randomised controlled trials.” Br J Cancer 123, no. 3 (August 2020): 333–34. https://doi.org/10.1038/s41416-020-0896-5.Full Text Link to Item
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Tao, Jun, Aminah Jatoi, Jeffrey Crawford, Wendy W. Lam, James C. Ho, Xiaofei Wang, and Herbert Pang. “Dietary Carbohydrates, Fiber, Whole Grain and the Risk of Lung Cancer: Conclusions from the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial (PLCO).” Current Developments in Nutrition 4 (June 2020): nzaa044_056-nzaa044_056. https://doi.org/10.1093/cdn/nzaa044_056.Full Text
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Wang, Xiao-Fei, Bo Liang, Da-Xiong Zeng, Wei Lei, Cheng Chen, Yan-Bin Chen, Jian-An Huang, Ning Gu, and Ye-Han Zhu. “The roles of MASPIN expression and subcellular localization in non-small cell lung cancer.” Biosci Rep 40, no. 5 (May 29, 2020). https://doi.org/10.1042/BSR20200743.Full Text Link to Item
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Jacobs, Corbin D., Junheng Gao, Xiaofei Wang, Jeffrey M. Clarke, Betty Tong, Neal E. Ready, Gita Suneja, Chris R. Kelsey, and Jordan A. Torok. “Definitive Radiotherapy for Inoperable Stage IIB Non-small-cell Lung Cancer: Patterns of Care and Comparative Effectiveness.” Clin Lung Cancer 21, no. 3 (May 2020): 238–46. https://doi.org/10.1016/j.cllc.2019.10.005.Full Text Link to Item
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Cao, Xiaowen, Apar Kishor Ganti, Thomas Stinchcombe, Melisa L. Wong, James C. Ho, Chen Shen, Yingzhou Liu, Jeffery Crawford, Herbert Pang, and Xiaofei Wang. “Predicting risk of chemotherapy-induced severe neutropenia: A pooled analysis in individual patients data with advanced lung cancer.” Lung Cancer 141 (March 2020): 14–20. https://doi.org/10.1016/j.lungcan.2020.01.004.Full Text Link to Item
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Giovacchini, Coral X., Edward R. Kessler, Christopher M. Merrick, Junheng Gao, Xiaofei Wang, Momen M. Wahidi, Scott L. Shofer, George Z. Cheng, and Kamran Mahmood. “Clinical and radiographic predictors of successful therapeutic bronchoscopy for the relief of malignant central airway obstruction.” Bmc Pulm Med 19, no. 1 (November 21, 2019): 219. https://doi.org/10.1186/s12890-019-0987-3.Full Text Link to Item
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Stinchcombe, Thomas E., Pasi A. Jänne, Xiaofei Wang, Erin M. Bertino, Jared Weiss, Lyudmila Bazhenova, Lin Gu, et al. “Effect of Erlotinib Plus Bevacizumab vs Erlotinib Alone on Progression-Free Survival in Patients With Advanced EGFR-Mutant Non-Small Cell Lung Cancer: A Phase 2 Randomized Clinical Trial.” Jama Oncol 5, no. 10 (October 1, 2019): 1448–55. https://doi.org/10.1001/jamaoncol.2019.1847.Full Text Link to Item
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Ganti, Apar Kishor, Xiaofei Wang, Thomas E. Stinchcombe, Yinpeng Wang, Jeffrey Bradley, Harvey J. Cohen, Karen Kelly, et al. “Clinical prognostic model for older patients with advanced non-small cell lung cancer.” J Geriatr Oncol 10, no. 4 (July 2019): 555–59. https://doi.org/10.1016/j.jgo.2019.02.007.Full Text Link to Item
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Zhang, Jianrong, Wenhua Liang, Hengrui Liang, Xiaofei Wang, and Jianxing He. “Endpoint surrogacy in oncological randomized controlled trials with immunotherapies: a systematic review of trial-level and arm-level meta-analyses.” Ann Transl Med 7, no. 11 (June 2019): 244. https://doi.org/10.21037/atm.2019.04.72.Full Text Link to Item
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Hamy, Anne-Sophie, Sandrine Tury, Xiaofei Wang, Junheng Gao, Jean-Yves Pierga, Sylvie Giacchetti, Etienne Brain, et al. “Celecoxib With Neoadjuvant Chemotherapy for Breast Cancer Might Worsen Outcomes Differentially by COX-2 Expression and ER Status: Exploratory Analysis of the REMAGUS02 Trial.” J Clin Oncol 37, no. 8 (March 10, 2019): 624–35. https://doi.org/10.1200/JCO.18.00636.Full Text Link to Item
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Schild, Steven E., Wen Fan, Thomas E. Stinchcombe, Everett E. Vokes, Suresh S. Ramalingam, Jeffrey D. Bradley, Karen Kelly, Herbert H. Pang, and Xiaofei Wang. “Toxicity Related to Radiotherapy Dose and Targeting Strategy: A Pooled Analysis of Cooperative Group Trials of Combined Modality Therapy for Locally Advanced Non-Small Cell Lung Cancer.” J Thorac Oncol 14, no. 2 (February 2019): 298–303. https://doi.org/10.1016/j.jtho.2018.09.021.Full Text Link to Item
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Stinchcombe, Thomas E., Wen Fan, Steven E. Schild, Everett E. Vokes, Jeff Bogart, Quynh-Thu Le, Charles R. Thomas, et al. “A pooled analysis of individual patient data from National Clinical Trials Network clinical trials of concurrent chemoradiotherapy for limited-stage small cell lung cancer in elderly patients versus younger patients.” Cancer 125, no. 3 (February 1, 2019): 382–90. https://doi.org/10.1002/cncr.31813.Full Text Link to Item
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Gao, Hao, Chris R. Kelsey, John Boyle, Tianyi Xie, Suzanne Catalano, Xiaofei Wang, and Fang-Fang Yin. “Impact of Esophageal Motion on Dosimetry and Toxicity With Thoracic Radiation Therapy.” Technol Cancer Res Treat 18 (2019): 1533033819849073. https://doi.org/10.1177/1533033819849073.Full Text Open Access Copy Link to Item
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Wang, Xiaofei, Fangfang Bai, Herbert Pang, and Stephen L. George. “Bias-adjusted Kaplan-Meier survival curves for marginal treatment effect in observational studies.” J Biopharm Stat 29, no. 4 (2019): 592–605. https://doi.org/10.1080/10543406.2019.1633659.Full Text Link to Item
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Wang, Ting, Xiaofei Wang, Haibo Zhou, Jianwen Cai, and Stephen L. George. “Auxiliary variable-enriched biomarker-stratified design.” Stat Med 37, no. 30 (December 30, 2018): 4610–35. https://doi.org/10.1002/sim.7938.Full Text Link to Item
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Altorki, Nasser K., Xiaofei Wang, Dennis Wigle, Lin Gu, Gail Darling, Ahmad S. Ashrafi, Rodney Landrenau, et al. “Perioperative mortality and morbidity after sublobar versus lobar resection for early-stage non-small-cell lung cancer: post-hoc analysis of an international, randomised, phase 3 trial (CALGB/Alliance 140503).” Lancet Respir Med 6, no. 12 (December 2018): 915–24. https://doi.org/10.1016/S2213-2600(18)30411-9.Full Text Link to Item
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Yang, Chi-Fu Jeffrey, Derek Y. Chan, Shivani A. Shah, Babatunde A. Yerokun, Xiaofei F. Wang, Thomas A. D’Amico, Mark F. Berry, and David H. Harpole. “Long-term Survival After Surgery Compared With Concurrent Chemoradiation for Node-negative Small Cell Lung Cancer.” Ann Surg 268, no. 6 (December 2018): 1105–12. https://doi.org/10.1097/SLA.0000000000002287.Full Text Link to Item
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Li, Zhiguo, Xiaofei Wang, Yuan Wu, and Kouros Owzar. “Sample size calculation for studies with grouped survival data.” Stat Med 37, no. 27 (November 30, 2018): 3904–17. https://doi.org/10.1002/sim.7847.Full Text Open Access Copy Link to Item
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Kinsey, Emily, Elizabeth Ajazi, Xiaofei Wang, Mary Ann Mayzie Johnston, and Jeffrey Crawford. “Predictors of Physical and Functional Loss in Advanced-Stage Lung Cancer Patients Receiving Platinum Chemotherapy.” J Thorac Oncol 13, no. 9 (September 2018): 1294–1301. https://doi.org/10.1016/j.jtho.2018.05.029.Full Text Link to Item
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Schild, Steven E., Herbert H. Pang, Wen Fan, Thomas E. Stinchcombe, Everett E. Vokes, Suresh S. Ramalingam, Jeffrey D. Bradley, Karen Kelly, and Xiaofei Wang. “Exploring Radiotherapy Targeting Strategy and Dose: A Pooled Analysis of Cooperative Group Trials of Combined Modality Therapy for Stage III NSCLC.” J Thorac Oncol 13, no. 8 (August 2018): 1171–82. https://doi.org/10.1016/j.jtho.2018.04.011.Full Text Link to Item
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Urbanic, James J., Xiaofei Wang, Jeffrey A. Bogart, Thomas E. Stinchcombe, Lydia Hodgson, Steven E. Schild, Lyudmila Bazhenova, Olwen Hahn, Ravi Salgia, and Everett E. Vokes. “Phase 1 Study of Accelerated Hypofractionated Radiation Therapy With Concurrent Chemotherapy for Stage III Non-Small Cell Lung Cancer: CALGB 31102 (Alliance).” Int J Radiat Oncol Biol Phys 101, no. 1 (May 1, 2018): 177–85. https://doi.org/10.1016/j.ijrobp.2018.01.046.Full Text Link to Item
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Yang, Chi-Fu Jeffrey, Frances McSherry, Nicholas R. Mayne, Xiaofei Wang, Mark F. Berry, Betty Tong, David H. Harpole, et al. “Surgical Outcomes After Neoadjuvant Chemotherapy and Ipilimumab for Non-Small Cell Lung Cancer.” Ann Thorac Surg 105, no. 3 (March 2018): 924–29. https://doi.org/10.1016/j.athoracsur.2017.09.030.Full Text Link to Item
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Nasution, Marlina D., and Xiaofei Wang. “Statistical issues and advances in cancer precision medicine research.” J Biopharm Stat 28, no. 2 (2018): 215–16. https://doi.org/10.1080/10543406.2017.1405013.Full Text Link to Item
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Janne, Pasi A., Xiaofei Wang, Mark A. Socinski, Jeffrey Crawford, Lin Gu, Marzia Capelletti, Martin J. Edelman, et al. “OUTCOME OF ADVANCED NSCLC PATIENTS WITH EGFR EXON 19 AND 21 MUTATIONS TREATED WITH ERLOTINIB (E) ALONE OR IN COMBINATION WITH CARBOPLATIN/PACLITAXEL (CP) IN CALGB 30406.” Journal of Thoracic Oncology 6, no. 6 (June 1, 2011): S447–48.Link to Item
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Dubey, Sarita, Pasi A. Jänne, Lee Krug, Herbert Pang, Xiaofei Wang, Robin Heinze, Colleen Watt, et al. “A phase II study of sorafenib in malignant mesothelioma: results of Cancer and Leukemia Group B 30307.” J Thorac Oncol 5, no. 10 (October 2010): 1655–61. https://doi.org/10.1097/JTO.0b013e3181ec18db.Full Text Link to Item
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Ready, Neal, Pasi A. Jänne, Jeffrey Bogart, Thomas Dipetrillo, Jennifer Garst, Stephen Graziano, Lin Gu, et al. “Chemoradiotherapy and gefitinib in stage III non-small cell lung cancer with epidermal growth factor receptor and KRAS mutation analysis: cancer and leukemia group B (CALEB) 30106, a CALGB-stratified phase II trial.” J Thorac Oncol 5, no. 9 (September 2010): 1382–90. https://doi.org/10.1097/JTO.0b013e3181eba657.Full Text Link to Item
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Schroen, Anneke T., Gina R. Petroni, Hongkun Wang, Robert Gray, Xiaofei F. Wang, Walter Cronin, Daniel J. Sargent, et al. “Preliminary evaluation of factors associated with premature trial closure and feasibility of accrual benchmarks in phase III oncology trials.” Clin Trials 7, no. 4 (August 2010): 312–21. https://doi.org/10.1177/1740774510374973.Full Text Link to Item
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Graziano, Stephen L., Lin Gu, Xiaofei Wang, Arthur H. Tatum, Robin T. Vollmer, Gary M. Strauss, Robert Kratzke, et al. “Prognostic significance of mucin and p53 expression in stage IB non-small cell lung cancer: a laboratory companion study to CALGB 9633.” J Thorac Oncol 5, no. 6 (June 2010): 810–17. https://doi.org/10.1097/jto.0b013e3181d89f95.Full Text Link to Item
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Wang, Xiaofei, and Haibo Zhou. “Design and inference for cancer biomarker study with an outcome and auxiliary-dependent subsampling.” Biometrics 66, no. 2 (June 2010): 502–11. https://doi.org/10.1111/j.1541-0420.2009.01280.x.Full Text Link to Item
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Partridge, Ann H., Laura Archer, Alice B. Kornblith, Julie Gralow, Debjani Grenier, Edith Perez, Antonio C. Wolff, et al. “Adherence and persistence with oral adjuvant chemotherapy in older women with early-stage breast cancer in CALGB 49907: adherence companion study 60104.” J Clin Oncol 28, no. 14 (May 10, 2010): 2418–22. https://doi.org/10.1200/JCO.2009.26.4671.Full Text Link to Item
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Aupérin, Anne, Cecile Le Péchoux, Estelle Rolland, Walter J. Curran, Kiyoyuki Furuse, Pierre Fournel, Jose Belderbos, et al. “Meta-analysis of concomitant versus sequential radiochemotherapy in locally advanced non-small-cell lung cancer.” J Clin Oncol 28, no. 13 (May 1, 2010): 2181–90. https://doi.org/10.1200/JCO.2009.26.2543.Full Text Link to Item
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Bogart, Jeffrey A., Lydia Hodgson, Stephen L. Seagren, A William Blackstock, Xiaofei Wang, Robert Lenox, Andrew T. Turrisi, et al. “Phase I study of accelerated conformal radiotherapy for stage I non-small-cell lung cancer in patients with pulmonary dysfunction: CALGB 39904.” J Clin Oncol 28, no. 2 (January 10, 2010): 202–6. https://doi.org/10.1200/JCO.2009.25.0753.Full Text Link to Item
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Wang, Xiaofei, Yougui Wu, and Haibo Zhou. “Outcome- and auxiliary-dependent subsampling and its statistical inference.” J Biopharm Stat 19, no. 6 (November 2009): 1132–50. https://doi.org/10.1080/10543400903243025.Full Text Link to Item
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Lilenbaum, Rogerio, Xiaofei Wang, Lin Gu, Jeffrey Kirshner, Keith Lerro, and Everett Vokes. “Randomized phase II trial of docetaxel plus cetuximab or docetaxel plus bortezomib in patients with advanced non-small-cell lung cancer and a performance status of 2: CALGB 30402.” J Clin Oncol 27, no. 27 (September 20, 2009): 4487–91. https://doi.org/10.1200/JCO.2009.22.7066.Full Text Link to Item
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D’Cunha, Jonathan, Xiaofei Wang, Shawn S. Groth, Robin T. Vollmer, Naif Z. Abraham, Debra L. Herzan, Lin Gu, et al. “The impact of occult micrometastases on survival following resection of stage I non-small cell lung cancer: final analysis of CALGB 9761.” Journal of Thoracic Oncology 4, no. 9 (September 1, 2009): S576–S576.Link to Item
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Govindan, Ramaswamy, Jeff Bogart, Xiaofei Wang, Lydia Hodgson, Robert A. Kratzke, and Everett E. Vokes. “A phase II study of pemetrexed, carboplatin and thoracic radiation with or without cetuximab in patients with locally advanced unresectable non-small cell lung cancer: CALGB 30407.” Journal of Thoracic Oncology 4, no. 9 (September 1, 2009): S371–72.Link to Item
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Govindan, Ramaswamy, Xiaofei Wang, Maria Q. Baggstrom, Susan Burdette-Radoux, Lydia Hodgson, Everett E. Vokes, Mark R. Green, and Mark R. Cancer and Leukemia Group B. “A phase II study of carboplatin, etoposide, and exisulind in patients with extensive small cell lung cancer: CALGB 30104.” J Thorac Oncol 4, no. 2 (February 2009): 220–26. https://doi.org/10.1097/JTO.0b013e3181951eb0.Full Text Link to Item
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Liptay, Michael J., Thomas A. D’amico, Chumy Nwogu, Todd L. Demmy, Xiaofei F. Wang, Lin Gu, Virginia R. Litle, Scott J. Swanson, Leslie J. Kohman, and Leslie J. Thoracic Surgery Subcommittee of the Cancer and Leukemia Group B. “Intraoperative sentinel node mapping with technitium-99 in lung cancer: results of CALGB 140203 multicenter phase II trial.” J Thorac Oncol 4, no. 2 (February 2009): 198–202. https://doi.org/10.1097/JTO.0b013e318194a2c3.Full Text Link to Item
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Miller, Antonius A., Xiaofei F. Wang, Lin Gu, Philip Hoffman, Jamil Khatri, Frank Dunphy, Martin J. Edelman, et al. “Phase II randomized study of dose-dense docetaxel and cisplatin every 2 weeks with pegfilgrastim and darbepoetin alfa with and without the chemoprotector BNP7787 in patients with advanced non-small cell lung cancer (CALGB 30303).” J Thorac Oncol 3, no. 10 (October 2008): 1159–65. https://doi.org/10.1097/JTO.0b013e318186fb0d.Full Text Link to Item
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Socinski, Mark A., A William Blackstock, Jeffrey A. Bogart, Xiaofei Wang, Michael Munley, Julian Rosenman, Lin Gu, et al. “Randomized phase II trial of induction chemotherapy followed by concurrent chemotherapy and dose-escalated thoracic conformal radiotherapy (74 Gy) in stage III non-small-cell lung cancer: CALGB 30105.” J Clin Oncol 26, no. 15 (May 20, 2008): 2457–63. https://doi.org/10.1200/JCO.2007.14.7371.Full Text Link to Item
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Kratzke, Robert A., Xiaofei Wang, Long Wong, Marian G. Kratzke, Mark R. Green, Everett E. Vokes, Nicholas J. Vogelzang, Hedy L. Kindler, Jeffrey A. Kern, and Jeffrey A. Cancer and Leukemia Group B. “Response to the methylation inhibitor dihydro-5-azacytidine in mesothelioma is not associated with methylation of p16INK4a: results of cancer and leukemia group B 159904.” J Thorac Oncol 3, no. 4 (April 2008): 417–21. https://doi.org/10.1097/JTO.0b013e318168da0a.Full Text Link to Item
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Edelman, Martin J., Dee Watson, Xiaofei Wang, Carl Morrison, Robert A. Kratzke, Scott Jewell, Lydia Hodgson, et al. “Eicosanoid modulation in advanced lung cancer: cyclooxygenase-2 expression is a positive predictive factor for celecoxib + chemotherapy--Cancer and Leukemia Group B Trial 30203.” J Clin Oncol 26, no. 6 (February 20, 2008): 848–55. https://doi.org/10.1200/JCO.2007.13.8081.Full Text Link to Item
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Rudin, Charles M., Ravi Salgia, Xiaofei Wang, Lydia D. Hodgson, Gregory A. Masters, Mark Green, and Everett E. Vokes. “Randomized phase II Study of carboplatin and etoposide with or without the bcl-2 antisense oligonucleotide oblimersen for extensive-stage small-cell lung cancer: CALGB 30103.” J Clin Oncol 26, no. 6 (February 20, 2008): 870–76. https://doi.org/10.1200/JCO.2007.14.3461.Full Text Link to Item
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Graziano, Stephen L., James E. Herndon, Mark A. Socinski, Xiaofei Wang, Dorothy Watson, Everett Vokes, Mark R. Green, and Mark R. Cancer and Leukemia Group B. “Phase II trial of weekly dose-dense paclitaxel in extensive-stage small cell lung cancer: cancer and leukemia group B study 39901.” J Thorac Oncol 3, no. 2 (February 2008): 158–62. https://doi.org/10.1097/JTO.0b013e318161225e.Full Text Link to Item
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Graziano, Stephen L., Lin Gu, Xiaofei F. Wang, Arthur H. Tatum, Robin T. Vollmer, Gary M. Strauss, Robert A. Kratzke, Mark R. Green, and Everett E. Vokes. “D5-01: Prognostic significance of molecular markers and clinical factors in stage ib non-small cell lung cancer (NSCLC): a laboratory companion study to CALGB 9633.” Journal of Thoracic Oncology 2, no. 8 (August 2007): S403–S403. https://doi.org/10.1097/01.jto.0000283278.97704.03.Full Text
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Miller, Antonius A., Xiaofei F. Wang, Jeffrey A. Bogart, Lydia D. Hodgson, Caio M. S. Rocha Lima, James E. Radford, Everett E. Vokes, Mark R. Green, and Mark R. Cancer and Leukemia Group B (CALGB). “Phase II trial of paclitaxel-topotecan-etoposide followed by consolidation chemoradiotherapy for limited-stage small cell lung cancer: CALGB 30002.” J Thorac Oncol 2, no. 7 (July 2007): 645–51. https://doi.org/10.1097/JTO.0b013e318074bbf5.Full Text Link to Item
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Perry, Michael C., Leslie J. Kohman, James A. Bonner, Lin Gu, Xiaofei Wang, Everett E. Vokes, and Mark R. Green. “A phase III study of surgical resection and paclitaxel/carboplatin chemotherapy with or without adjuvant radiation therapy for resected stage III non-small-cell lung cancer: Cancer and Leukemia Group B 9734.” Clin Lung Cancer 8, no. 4 (January 2007): 268–72. https://doi.org/10.3816/CLC.2007.n.005.Full Text Link to Item
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Wang, Xiaofei, and Haibo Zhou. “A semiparametric empirical likelihood method for biased sampling schemes with auxiliary covariates.” Biometrics 62, no. 4 (December 2006): 1149–60. https://doi.org/10.1111/j.1541-0420.2006.00612.x.Full Text Link to Item
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Riedel, Richard F., Xiaofei Wang, Meg McCormack, Eric Toloza, Gustavo S. Montana, Gilbert Schreiber, and Michael J. Kelley. “Impact of a multidisciplinary thoracic oncology clinic on the timeliness of care.” J Thorac Oncol 1, no. 7 (September 2006): 692–96.Link to Item
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Pincus, T., X. Wang, C. Chung, T. Sokka, and G. G. Koch. “Erratum: Patient preference in a crossover clinical trial of patients with osteoarthritis of the knee or hip: Face validity of self-report questionnaire ratings (Journal of Rheumatology (2005) 32 (533-539)).” Journal of Rheumatology 32, no. 5 (May 1, 2005): 966.
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Pincus, Theodore, Xiaofei Wang, Cecilia Chung, Tuulikki Sokka, and Gary G. Koch. “Patient preference in a crossover clinical trial of patients with osteoarthritis of the knee or hip: face validity of self-report questionnaire ratings.” J Rheumatol 32, no. 3 (March 2005): 533–39.Link to Item
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Wang, Youfa, and Xiaofei Wang. “How do statistical properties influence findings of tracking (maintenance) in epidemiologic studies? An example of research in tracking of obesity.” Eur J Epidemiol 18, no. 11 (2003): 1037–45. https://doi.org/10.1023/a:1026196310041.Full Text Link to Item
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Wang, Youfa, and Xiaofei Wang. “Re: "Tracking of cardiovascular risk factors: the Tromsø Study, 1979, 1995".” Am J Epidemiol 155, no. 12 (June 15, 2002): 1144–45. https://doi.org/10.1093/aje/155.12.1144.Full Text Link to Item
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Pincus, T., G. G. Koch, T. Sokka, J. Lefkowith, F. Wolfe, J. M. Jordan, G. Luta, et al. “A randomized, double-blind, crossover clinical trial of diclofenac plus misoprostol versus acetaminophen in patients with osteoarthritis of the hip or knee.” Arthritis Rheum 44, no. 7 (July 2001): 1587–98. https://doi.org/10.1002/1529-0131(200107)44:7<1587::AID-ART282>3.0.CO;2-X.Full Text Link to Item
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Wang, X., and C. A. Burbeck. “Scaled medial axis representation: evidence from position discrimination task.” Vision Res 38, no. 13 (June 1998): 1947–59. https://doi.org/10.1016/s0042-6989(97)00299-x.Full Text Link to Item
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Wang, X. F., and C. A. Burbeck. “Enhanced position sensitivity at scaled medial loci.” Investigative Ophthalmology and Visual Science 37, no. 3 (February 15, 1996).
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Book Sections
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George, Stephen, Xiaofei Wang, and Herbert Pang. “Endpoints for Cancer Clinical Trials.” In Cancer Clinical Trials: Current and Controversial Issues in Design and Analysis, edited by Stephen George, Xiaofei Wang, and Herbert Pang, 3–36. Chapman & Hall, 2016.
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George, Stephen, Xiaofei Wang, and Herbert Pang. “Endpoints for Cancer Clinical Trials.” In Cancer Clinical Trials: Current and Controversial Issues in Design and Analysis, edited by Stephen George, Xiaofei Wang, and Herbert Pang, 3–36. Chapman & Hall, 2016.
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George, Matthew O., and Matthew O. Wang. “Targeted Clinical Trials.” In Designs for Clinical Trials, edited by Matthew O. Harrington, 157–77. Springer, n.d.
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George, Matthew O., and Matthew O. Wang. “Targeted Clinical Trials.” In Designs for Clinical Trials, edited by Matthew O. Harrington, 157–77. Springer, n.d.
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Conference Papers
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Saltos, Andreas, Hong Zheng, Christy Arrowood, Georgia Beasley, James Ronald, Ghassan El-Haddad, Uzma Khan, et al. “1132 Impact of intralesional oncolytic viral therapy targetingin situactivation of CD40 and type 1 interferon signaling pathways on the TME and systemic T cell immunity in murine models and cancer patients.” In Regular and Young Investigator Award Abstracts. BMJ Publishing Group Ltd, 2022. https://doi.org/10.1136/jitc-2022-sitc2022.1132.Full Text
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Pang, Herbert, Tiffany H. Leung, James C. M. Ho, Wendy W. T. Lam, and Xiaofei F. Wang. “Assessing surrogacy using restricted mean survival time ratio for overall survival in liver cancer immunotherapy studies.” In Journal of Clinical Oncology, 40:E16222–E16222, 2022.Link to Item
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Bogart, Jeffrey A., Xiaofei F. Wang, Gregory A. Masters, Junheng Gao, Ritsuko Komaki, Charles S. Kuzma, John Heymach, et al. “Phase 3 comparison of high-dose once-daily (QD) thoracic radiotherapy (TRT) with standard twice-daily (BID) TRT in limited stage small cell lung cancer (LSCLC): CALGB 30610 (Alliance)/RTOG 0538.” In Journal of Clinical Oncology, 39:8505–8505. American Society of Clinical Oncology (ASCO), 2021. https://doi.org/10.1200/jco.2021.39.15_suppl.8505.Full Text
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Ross, Helen J., David E. Kozono, James John Urbanic, Terence Marques Williams, Carter DuFrane, Ilze Bara, Katja Schulze, et al. “AFT-16: Phase II trial of neoadjuvant and adjuvant atezolizumab and chemoradiation (CRT) for stage III non-small cell lung cancer (NSCLC).” In Journal of Clinical Oncology, 39:8513–8513. American Society of Clinical Oncology (ASCO), 2021. https://doi.org/10.1200/jco.2021.39.15_suppl.8513.Full Text
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Clarke, Jeffrey Melson, Xiaofei F. Wang, Lin Gu, Marvaretta Miesha Stevenson, Tom Stinchcombe, Sundhar Ramalingam, Scott Joseph Antonia, et al. “Interim results from the OPTIMAL trial: A phase II clinical trial of combination nivolumab, ipilimumab, and taxane in patients with untreated metastatic non-small cell lung cancer (NSCLC).” In Journal of Clinical Oncology, Vol. 38, 2020.Link to Item
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Ross, Helen J., Chen Hu, Kristin Ann Higgins, Salma K. Jabbour, David E. Kozono, Taofeek Kunle Owonikoko, Benjamin Movsas, et al. “NRG Oncology/Alliance LU005: A phase II/III randomized clinical trial of chemoradiation versus chemoradiation plus atezolizumab in limited stage small cell lung cancer.” In Journal of Clinical Oncology, Vol. 38, 2020.Link to Item
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Ross, Helen J., David E. Kozono, James John Urbanic, Terence Marques Williams, Carter Dufrane, Ilze Bara, Mayank Gandhi, et al. “AFT-16: Phase II trial of atezolizumab before and after definitive chemoradiation (CRT) for unresectable stage III non-small cell lung cancer (NSCLC).” In Journal of Clinical Oncology, Vol. 38, 2020.Link to Item
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Dudek, Arkadiusz Z., Xiaofei F. Wang, Lin Gu, Tom Stinchcombe, Robert Arthur Kratzke, Everett E. Vokes, and Hedy L. Kindler. “Randomized phase 2 study of maintenance pemetrexed (Pem) versus observation (Obs) for patients (pts) with malignant pleural mesothelioma (MPM) without progression after first-line chemotherapy: Cancer and Leukemia Group B (CALGB) 30901 (Alliance).” In Journal of Clinical Oncology, Vol. 37. AMER SOC CLINICAL ONCOLOGY, 2019.Link to Item
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Hensing, Thomas A., Xiaofei F. Wang, Junheng Gao, Tom Stinchcombe, Michael V. Knopp, Arkadiusz Z. Dudek, Stephen L. Graziano, et al. “Randomized multicenter phase II trial evaluating the sequencing of PD-1 inhibition with pembrolizumab (P) and standard platinum-based chemotherapy (C) in patients (pts) with metastatic non-small cell lung cancer (NSCLC) (AFT-09).” In Journal of Clinical Oncology, Vol. 37. AMER SOC CLINICAL ONCOLOGY, 2019.Link to Item
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Stinchcombe, Tom, Robert Charles Doebele, Xiaofei F. Wang, David E. Gerber, Leora Horn, and D Ross Camidge. “Preliminary results of single arm phase 2 trial of brigatinib in patients (pts) with progression disease (PD) after next-generation (NG) anaplastic lymphoma kinase (ALK) tyrosine kinase inhibitors (TKIs) in ALK plus non-small cell lung cancer (NSCLC).” In Journal of Clinical Oncology, Vol. 37. AMER SOC CLINICAL ONCOLOGY, 2019.Link to Item
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Stinchcombe, T. E., P. A. Janne, X. Wang, E. M. Bertino, J. M. Weiss, L. Bazhenova, L. Gu, et al. “A randomized phase II trial of erlotinib or erlotinib and bevacizumab in patients with advanced EGFR mutant non-small cell lung cancer (NSCLC).” In Ann Oncol, 29 Suppl 8:viii522, 2018. https://doi.org/10.1093/annonc/mdy292.066.Full Text Link to Item
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Stinchcombe, T. E., W. Fan, S. E. Schild, E. E. Vokes, J. Bogart, Q. -. T. X. Le, C. R. Thomas, et al. “A pooled analysis of individual patient data (IPD) of concurrent chemoradiotherapy for limited-stage small cell lung cancer (LS-SCLC) in elderly compared to younger patients (pts) who participated in US National Cancer Institute cooperative group studies.” In Ann Oncol, 29 Suppl 8:viii597–98, 2018. https://doi.org/10.1093/annonc/mdy298.004.Full Text Link to Item
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Kinsey, Emily, Elizabeth Ajazi, Xiaofei F. Wang, Mary Ann Johnston, and Jeffrey Crawford. “The importance of body composition and physical function on overall survival (OS) in non-small cell lung cancer (NSCLC) patients receiving platinum based chemotherapy (PBCT).” In Journal of Clinical Oncology, 36:e21088–e21088. American Society of Clinical Oncology (ASCO), 2018. https://doi.org/10.1200/jco.2018.36.15_suppl.e21088.Full Text
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Ross, Helen J., David E. Kozono, James John Urbanic, Terence Marques Williams, Carter Dufrane, Ilze Bara, Mayank Gandhi, et al. “Phase II trial of atezolizumab before and after definitive chemoradiation for unresectable stage III NSCLC.” In Journal of Clinical Oncology, 36:TPS8585–TPS8585. American Society of Clinical Oncology (ASCO), 2018. https://doi.org/10.1200/jco.2018.36.15_suppl.tps8585.Full Text
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Wang, Ting, Xiaofei Wang, Haibo Zhou, Jianwen Cai, and Stephen L. George. “Biomarker stratified design enriched by auxiliary variables.” In Trials, Vol. 18. BIOMED CENTRAL LTD, 2017.Link to Item
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Yi, John, Jeffrey Melson Clarke, Patrick Healy, Xiaofei F. Wang, Debra Shoemaker, Mark W. Onaitis, Chelsae Dumbauld, et al. “Immune profiling of circulating T cells and TILs following neoadjuvant ipilimumab and chemotherapy in non-small cell lung cancer (NSCLC).” In Journal of Clinical Oncology, 35:26–26. American Society of Clinical Oncology (ASCO), 2017. https://doi.org/10.1200/jco.2017.35.7_suppl.26.Full Text
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Pang, Herbert, Kang Yan, Robert Kratzke, Thomas Stinchcombe, Jeffrey Crawford, Hedy Kindler, Everett Vokes, and Xiaofei Wang. “P3.03-036 Prognostic Model for Mesothelioma Based on Cancer and Leukemia Group B (CALGB) Trials (Alliance).” In Journal of Thoracic Oncology, 12:S1367–S1367. Elsevier BV, 2017. https://doi.org/10.1016/j.jtho.2016.11.1935.Full Text
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Stinchcombe, Thomas, Ying Zhang, Everett Vokes, Joan Schiller, Jeffrey Bradley, Karen Kelly, Walter Curran, et al. “MA06.10 A Pooled Analysis Comparing the Outcomes of Elderly to Younger Patients on NCTN Trials of Concurrent CCRT for Stage 3 NSCLC.” In Journal of Thoracic Oncology, 12:S374–75. Elsevier BV, 2017. https://doi.org/10.1016/j.jtho.2016.11.422.Full Text
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Wang, Xiaofei, Xiaowen Cao, Thomas Stinchcombe, Jeffrey Bradley, Alex Adjei, David R. Gandara, Suresh Ramalingam, Herbert Pang, Everett Vokes, and Jeffrey Crawford. “P2.03a-055 Predicting Risk of Chemotherapy-Induced Severe Neutropenia in Lung Patients: A Pooled Analysis of US Cooperative Group Trials.” In Journal of Thoracic Oncology, 12:S922–23. Elsevier BV, 2017. https://doi.org/10.1016/j.jtho.2016.11.1265.Full Text
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Stinchcombe, Tom, Ying J. Zhang, Everett E. Vokes, Joan H. Schiller, Jeffrey D. Bradley, Walter John Curran, Benjamin Movsas, et al. “A pooled analysis of concurrent chemoradiotherapy (CCRT) for patients with stage III non-small cell lung cancer (NSCLC) who participated in U.S. cooperative group trials: Comparing the outcomes of elderly to younger patients (pts).” In Journal of Clinical Oncology, 34:8508–8508. American Society of Clinical Oncology (ASCO), 2016. https://doi.org/10.1200/jco.2016.34.15_suppl.8508.Full Text
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Yang, Chi-Fu Jeffrey, Derek Y. Chan, Babatunde Yerokun, Xiaofei F. Wang, Betty Caroline Tong, Thomas A. D’Amico, Mark W. Onaitis, Matthew G. Hartwig, Mark F. Berry, and David Harpole. “Surgery versus optimal medical management of early-stage small cell lung cancer.” In Journal of Clinical Oncology, 34:8511–8511. American Society of Clinical Oncology (ASCO), 2016. https://doi.org/10.1200/jco.2016.34.15_suppl.8511.Full Text
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Edelman, Martin J., Xiaofei Wang, Lydia Hodgson, Richard T. Cheney, Maria Baggstrom, Thomas Sachdev, Ajeet Gajra, et al. “Abstract CT238: Phase III randomized, placebo controlled trial of COX-2 inhibition in addition to standard chemotherapy for advanced non-small cell lung cancer (NSCLC):CALGB 30801 (Alliance).” In Cancer Research, 74:CT238–CT238. American Association for Cancer Research (AACR), 2014. https://doi.org/10.1158/1538-7445.am2014-ct238.Full Text
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Socinski, Mark A., Xiaofei F. Wang, Maria Quintos Baggstrom, Lin Gu, Thomas E. Stinchcombe, Martin J. Edelman, Sherman Baker JR, Heather Dorothy Mannuel, Jeffrey Crawford, and Everett E. Vokes. “Sunitinib (S) switch maintenance in advanced non-small cell lung cancer (NSCLC): An ALLIANCE (CALGB 30607), randomized, placebo-controlled phase III trial.” In Journal of Clinical Oncology, 32:8040–8040. American Society of Clinical Oncology (ASCO), 2014. https://doi.org/10.1200/jco.2014.32.15_suppl.8040.Full Text
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Stinchcombe, Tom, Lynette M. Sholl, Xiaofei F. Wang, Lin Gu, Mark A. Socinski, Scott J. Rodig, Marzia Capelletti, et al. “An analysis of the prevalence of HER2 and KRAS mutations, and ALK rearrangements and clinical outcomes in Cancer and Leukemia Group B [CALGB (Alliance)] trial 30406 in advanced non-small cell lung cancer (NSCLC).” In Journal of Clinical Oncology, Vol. 31. AMER SOC CLINICAL ONCOLOGY, 2013.Link to Item
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Pang, Herbert, Lin Gu, William Richards, Jeffery Crawford, Mark Green, Everett Vokes, and Xiaofei Wang. “Abstract 4707: Validation of survival prognostic models for non-small-cell lung cancer instage- and age-specific groups.” In Cancer Research, 73:4707–4707. American Association for Cancer Research (AACR), 2013. https://doi.org/10.1158/1538-7445.am2013-4707.Full Text
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Heist, Rebecca Suk, Xiaofei F. Wang, Lydia Hodgson, Gregory Alan Otterson, Tom Stinchcombe, Everett E. Vokes, and Mark A. Socinski. “CALGB 30704: A randomized phase II study to assess the efficacy of pemetrexed or sunitinib or pemetrexed plus sunitinib in the second-line treatment of advanced non-small cell lung cancer (NSCLC).” In Journal of Clinical Oncology, Vol. 30. AMER SOC CLINICAL ONCOLOGY, 2012.Link to Item
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Janne, Pasi A., Xiaofei F. Wang, Lee M. Krug, Lydia Hodgson, Everett E. Vokes, and Hedy L. Kindler. “Phase II trial of sorafenib (bay 43-9006) in malignant mesothelioma: CALGB 30307.” In Annals of Oncology, 17:216–17. OXFORD UNIV PRESS, 2006.Link to Item
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- Teaching & Mentoring
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Recent Courses
- Scholarly, Clinical, & Service Activities
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Service to the Profession
- Associate editor for Statistics in Biopharmaceutical Research (SBR). 2016 2016
- Editorial board for Chinese Clinical Oncology (CCO). 2016 2016
- Deputy statistical editor for Journal of Thoracic and Cardiovascular Surgery. 2014 2014
- Director of Statistics for Alliance for Clinical Trials in Oncology, NCI/NCTN. 2014 2014
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