Hermione Xu

Preprint · November 13, 2025 Proprioceptive feedback from muscles is essential for continuous monitoring and precise control of limb movement, yet how such peripheral feedback is integrated into ongoing descending motor cortical dynamics remains largely unclear. Here we used precisely ... Full text Link to item Cite

Cortico-thalamic communication for action coordination in a skilled motor sequence.

Preprint · October 30, 2024 The coordination of forelimb and orofacial movements to compose an ethological reach-to-consume behavior likely involves neural communication across brain regions. Leveraging wide-field imaging and photo-inhibition to survey across the cortex, we identifie ... Full text Link to item Cite

Cortical glutamatergic projection neuron types contribute to distinct functional subnetworks.

Journal article Nat Neurosci · March 2023 The cellular basis of cerebral cortex functional architecture remains not well understood. A major challenge is to monitor and decipher neural network dynamics across broad cortical areas yet with projection-neuron-type resolution in real time during behav ... Full text Link to item Cite

Bilateral Habenula deep brain stimulation for treatment-resistant depression: clinical findings and electrophysiological features.

Journal article Translational psychiatry · February 2022 Deep brain stimulation (DBS) of structures in the brain's reward system is a promising therapeutic option for patients with treatment-resistant depression (TRD). Recently, DBS of the habenula (HB) in the brain's anti-reward system has also been reported to ... Full text Cite

A cortical circuit for orchestrating oromanual food manipulation

Preprint · 2022 ABSTRACT The seamless coordination of hands and mouth—whether in humans eating corn on the cob or mice extracting sunflower seeds—represents one of evolution’s most sophisticated motor achievements. Whereas spinal and brainstem circuits implement ... Full text Cite

Remote video-based outcome measures of patients with Parkinson's disease after deep brain stimulation using smartphones: a pilot study.

Journal article Neurosurgical focus · November 2021 ObjectiveTo provide better postoperative healthcare for patients with Parkinson's disease (PD) who received deep brain stimulation (DBS) surgery and to allow surgeons improved tracking of surgical outcomes, the authors sought to examine the applic ... Full text Cite

Recharging Difficulty With Pulse Generator After Deep Brain Stimulation: A Case Series of Five Patients.

Journal article Frontiers in neuroscience · January 2021 Background: Deep brain stimulation (DBS) is a well-established treatment for a variety of movement disorders. Rechargeable cell technology was introduced to pulse generator more than 10 years ago and brought great benefits to patients. However, with ... Full text Cite

Deep Brain Stimulation-Induced Transient Effects in the Habenula.

Journal article Frontiers in psychiatry · January 2021 The habenula, located in the epithalamus, has been implicated in various psychiatric disorders including mood disorders and schizophrenia. This study explored the transient effects of deep brain stimulation in the habenula. Each of the four patients (two w ... Full text Cite

Effects of Unilateral Stimulation in Parkinson's Disease: A Randomized Double-Blind Crossover Trial.

Journal article Frontiers in neurology · January 2021 IntroductionPrevious studies have shown that subthalamic nucleus (STN) and unilateral globus pallidus interna (GPi) are similarly effective in the deep brain stimulation (DBS) treatment of motor symptoms. However, the counterintuitively more commo ... Full text Cite