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Yi-Ju Li

Professor of Biostatistics & Bioinformatics
Biostatistics & Bioinformatics, Division of Integrative Genomics
Duke Box 104775, Durham, NC 27708
300 North Duke Street, 47-122 Carmichael Warehouse, Durham, NC 27701


My research interest is in statistical genetics, including statistical method development and its application for understanding the genetic predisposition of human complex diseases. Here is the list of research topics:
  • Statistical genetics: development of family-based association methods for quantitative traits with or without censoring and for detecting X-linked genes for disease risk.  With the availability of next generation sequencing data, we have ongoing projects to develop the association methods for testing rare variants for different phenotypic measures.  
  • Genetics of Alzheimer's disease (AD) and Fuchs endothelial corneal dystrophy (FECD).
  • Genetic basis of age-at-onset of Alzheimer disease. 
  • Peri-operative genomic studies. Investigate the genetic risk factors for postoperative outcomes of patients underwent non-emergent coronary artery bypass grafting with cardiopulmonary bypass.

Current Appointments & Affiliations

Professor of Biostatistics & Bioinformatics · 2021 - Present Biostatistics & Bioinformatics, Division of Integrative Genomics, Biostatistics & Bioinformatics
Member of Duke Molecular Physiology Institute · 2014 - Present Duke Molecular Physiology Institute, Duke Molecular Physiology Institute

Web Links

Li Webpage