Overview
Dr. Yongmei Liu is a genetic epidemiologist with appointments in Cardiology/Medicine and Neurology. Her primary interests are to better understand the molecular mechanisms of aging-related inflammatory diseases including diabetes, atherosclerosis, and Alzheimer’s disease by studying genome, the interplay of genetic and environmental factors, and epigenomic and transcriptomic profiles. The combination of an unbiased genome-wide search in large sample sizes of disease relevant tissues/cells with longitudinal and randomized clinical trial designs, followed up by in vitro and in vivo experiments, is providing novel biomarkers for risk prediction and new insights into mechanisms that are involved in inflammatory diseases.
Current Appointments & Affiliations
Professor of Medicine
·
2020 - Present
Medicine, Cardiology,
Medicine
Professor in Population Health Sciences
·
2021 - Present
Population Health Sciences,
Basic Science Departments
Member of Duke Molecular Physiology Institute
·
2018 - Present
Duke Molecular Physiology Institute,
Institutes and Centers
Recent Publications
Allergen-Specific IgE and IgG4 Signatures in IgG4-Related Disease Revealed by a Large-Scale PhIP-Seq Study.
Journal Article Allergy · May 2026 OBJECTIVES: Immunoglobulin G4-related disease (IgG4-RD) is frequently accompanied by allergic/atopic manifestations, yet its allergen-specific antibody landscape remains poorly defined. Therefore, we detected allergen-specific IgE and IgG4 levels in patien ... Full text Link to item CiteThe treatment of myocardial ischemia-reperfusion injury: potential roles of natural drug modulating CaMKII
Journal Article Frontiers in Pharmacology · January 1, 2026 Myocardial ischemia-reperfusion injury (MIRI) represents a significant challenge in the treatment of cardiovascular diseases, with its complex pathogenesis involving multiple signaling pathways, such as calcium overload, oxidative stress, inflammatory resp ... Full text CiteMechanism of Kidney-tonifying Therapy in Treating Panvascular Disease Through "Immune-metabolic-genetic" Axis
Journal Article Chinese Journal of Experimental Traditional Medical Formulae · January 1, 2026 ［Abstract］ Pan vascular disease（PVD）is a systemic vascular disorder that has become the leading cause of death among the Chinese residents，and there is currently a lack of effective systemic treatment options. Clinical practice has found that the tradition ... Full text CiteRecent Grants
Cognitively Healthy Nonagenarians in the Cross Cohort Collaboration (CCC)
ResearchPrincipal Investigator · Awarded by The University of Texas at San Antonio · 2026 - 2031Metal Exposures, Omics, and AD/ADRD risk in Diverse US Adults
ResearchPrincipal Investigator · Awarded by Columbia University · 2026 - 2030Subclinical Vascular Contributions to Alzheimer's Disease: The Multi-Ethnic Study of Atherosclerosis (MESA) Multisite Study of AD
ResearchPrincipal Investigator · Awarded by Wake Forest University · 2024 - 2029View All Grants
Education
Johns Hopkins Unversity, Bloomberg School of Public Health ·
2004
Ph.D.
Bengbu Medical College (China) ·
1991
M.D.