Scholars@Duke
Yuan Wu

Yuan Wu

Associate Professor in Biostatistics & Bioinformatics
Biostatistics & Bioinformatics, Division of Biostatistics
yuan.wu@duke.edu
Duke Box 2721, Durham, NC 27710
2424 Erwin Road, 11101 Hock Plaza Suite 1102, Durham, NC 27710

Overview

Survival analysis, Sequential clinical trial design, Machine learning, Causal inference, Non/Semi-parametric method, Statistical computing

Current Appointments & Affiliations

Associate Professor in Biostatistics & Bioinformatics · 2022 - Present Biostatistics & Bioinformatics, Division of Biostatistics, Biostatistics & Bioinformatics
Member of the Duke Cancer Institute · 2021 - Present Duke Cancer Institute, Institutes and Centers

Recent Publications

Intensifying Salvage Therapy in Prostate-specific Antigen Recurrent Prostate Cancer After Radical Prostatectomy with Apalutamide, Salvage Radiation, and Docetaxel: The Phase 2 STARTAR Trial.

Journal Article Eur Urol Oncol · April 2025 BACKGROUND AND OBJECTIVE: Androgen deprivation therapy (ADT) with salvage radiation therapy (RT) improves survival for patients with prostate-specific antigen (PSA) recurrence after radical prostatectomy (RP) for prostate cancer (PC), but many patients suf ... Full text Link to item Cite

Sequential design for paired ordinal categorical outcome.

Journal Article Stat Methods Med Res · March 31, 2025 This study addresses a critical gap in the design of clinical trials that use grouped sequential designs for one-sample or paired ordinal categorical outcomes. Single-arm experiments, such as those using the modified Rankin Scale in stroke trials, undersco ... Full text Link to item Cite

Group Sequential Test for Two-Sample Ordinal Outcome Measures.

Journal Article Stat Med · March 15, 2025 Group sequential trials include interim monitoring points to potentially reach futility or efficacy decisions early. This approach to trial design can safeguard patients, provide efficacious treatments for patients early, and save money and time. Group seq ... Full text Link to item Cite
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Recent Grants

Assessment of the Optimal Settings of TFL for Laser Lithotripsy and Associated Thermal Injury Risk

ResearchCo Investigator · Awarded by National Institutes of Health · 2025 - 2028

Kidney Cancer Research Program Clinical Consortium Duke University Clinical Trial Site Award

ResearchBiostatistician · Awarded by Department of Defense · 2024 - 2028

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Education, Training & Certifications

University of Iowa · 2010 Ph.D.