Overview
Huanghe Yang Laboratory
Current Appointments & Affiliations
Student
Biochemistry,
Basic Science Departments
Student
Neurobiology,
Basic Science Departments
Recent Publications
Targeting PIEZO1-TMEM16F Coupling to Mitigate Sickle Cell Disease Complications.
Journal Article Am J Hematol · December 2025 A deeper understanding of sickle cell disease (SCD) pathophysiology is critical for identifying novel therapeutic targets. A hallmark of SCD is abnormal phosphatidylserine (PS) exposure on sickle red blood cells (RBCs), which contributes to anemia, thrombo ... Full text Open Access Link to item CiteDeciphering and disrupting PIEZO1-TMEM16F interplay in hereditary xerocytosis
Journal Article BLOOD · 2024 Full text CitePIEZO1-TMEM16F Interplay in Hereditary Xerocytosis
Conference Blood · November 2, 2023 Cell surface exposure of phosphatidylserine (PS), an anionic phospholipid that is usually confined to the inner leaflet of the plasma membrane, triggers a plethora of cellular responses. PS exposure in RBCs contributes ... Full text CiteRecent Grants
Role of TMEM16F in Hereditary Xerocytosis Manifestations
FellowshipFellow · Awarded by American Society of Hematology · 2023 - 2025View All Grants