Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Physics Resident, Thomas Jefferson University 2009 - 2012
  • Research Fellow, Memorial Sloan-Kettering Cancer Center 2006 - 2009
  • Ph.D., Tsinghua University (China) 2006
• 

  Previous Appointments & Affiliations

  • Assistant Professor of Radiation Oncology, Radiation Oncology, Clinical Science Departments 2013 - 2020
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Erickson, Brett G., Bradley G. Ackerson, Chris R. Kelsey, Fang-Fang Yin, Justus Adamson, and Yunfeng Cui. “The Effect of Various Dose Normalization Strategies When Implementing Linear Boltzmann Transport Equation Dose Calculation for Lung Stereotactic Body Radiation Therapy Planning.” Pract Radiat Oncol, February 24, 2022. https://doi.org/10.1016/j.prro.2022.02.005.
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    • Shi, Liting, Quan Chen, Susan Barley, Yunfeng Cui, Lu Shang, Jianfeng Qiu, and Yi Rong. “Benchmarking of Deformable Image Registration for Multiple Anatomic Sites Using Digital Data Sets With Ground-Truth Deformation Vector Fields.” Pract Radiat Oncol 11, no. 5 (September 2021): 404–14. https://doi.org/10.1016/j.prro.2021.02.012.
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    • Rong, Yi, Mihaela Rosu-Bubulac, Stanley H. Benedict, Yunfeng Cui, Russell Ruo, Tanner Connell, Rojano Kashani, et al. “Rigid and Deformable Image Registration for Radiation Therapy: A Self-Study Evaluation Guide for NRG Oncology Clinical Trial Participation.” Pract Radiat Oncol 11, no. 4 (July 2021): 282–98. https://doi.org/10.1016/j.prro.2021.02.007.
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    • Cui, Yunfeng, Hao Gao, Jiahan Zhang, John P. Kirkpatrick, and Fang-Fang Yin. “Retrospective quality metrics review of stereotactic radiosurgery plans treating multiple targets using single-isocenter volumetric modulated arc therapy.” Journal of Applied Clinical Medical Physics 21, no. 6 (June 2020): 93–99. https://doi.org/10.1002/acm2.12869.
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    • Wang, Chunhao, Chenyang Liu, Yushi Chang, Kyle Lafata, Yunfeng Cui, Jiahan Zhang, Yang Sheng, Yvonne Mowery, David Brizel, and Fang-Fang Yin. “Dose-Distribution-Driven PET Image-Based Outcome Prediction (DDD-PIOP): A Deep Learning Study for Oropharyngeal Cancer IMRT Application.” Front Oncol 10 (2020): 1592. https://doi.org/10.3389/fonc.2020.01592.
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    • Hong, Julian C., Yunfeng Cui, Bhavik N. Patel, Christel N. Rushing, Austin M. Faught, Jared S. Eng, Kyle Higgins, et al. “Association of Interim FDG-PET Imaging During Chemoradiation for Squamous Anal Canal Carcinoma With Recurrence.” Int J Radiat Oncol Biol Phys 102, no. 4 (November 15, 2018): 1046–51. https://doi.org/10.1016/j.ijrobp.2018.04.062.
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    • Tandberg, Daniel J., Yunfeng Cui, Christel N. Rushing, Julian C. Hong, Bradley G. Ackerson, Daniele Marin, Xuenfeng Zhang, Brian G. Czito, Christopher W. Willett, and Manisha Palta. “Intratreatment Response Assessment With 18F-FDG PET: Correlation of Semiquantitative PET Features With Pathologic Response of Esophageal Cancer to Neoadjuvant Chemoradiotherapy.” Int J Radiat Oncol Biol Phys 102, no. 4 (November 15, 2018): 1002–7. https://doi.org/10.1016/j.ijrobp.2018.07.187.
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    • Cui, Yunfeng, James Bowsher, Jing Cai, and Fang-Fang Yin. “Impact of moving target on measurement accuracy in 3D and 4D PET imaging-a phantom study.” Adv Radiat Oncol 2, no. 1 (January 2017): 94–100. https://doi.org/10.1016/j.adro.2016.12.002.
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    • Hong, J. C., J. Eng, A. Faught, K. Higgins, Y. Cui, F. F. Yin, S. K. Das, B. Czito, C. G. Willett, and M. Palta. “Interim FDG Positron Emission Tomography Imaging During Chemoradiation for Squamous Anal Canal Carcinoma.” Int J Radiat Oncol Biol Phys 96, no. 2S (October 1, 2016): E183. https://doi.org/10.1016/j.ijrobp.2016.06.1050.
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    • Cui, Yunfeng, Wenzhou Chen, Feng-Ming Spring Kong, Lindsey A. Olsen, Ronald E. Beatty, Peter G. Maxim, Timothy Ritter, et al. “Contouring variations and the role of atlas in non-small cell lung cancer radiation therapy: Analysis of a multi-institutional preclinical trial planning study.” Pract Radiat Oncol 5, no. 2 (March 2015): e67–75. https://doi.org/10.1016/j.prro.2014.05.005.
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    • Gondi, Vinai, Yunfeng Cui, Minesh P. Mehta, Denise Manfredi, Ying Xiao, James M. Galvin, Howard Rowley, and Wolfgang A. Tome. “Real-time pretreatment review limits unacceptable deviations on a cooperative group radiation therapy technique trial: quality assurance results of RTOG 0933.” Int J Radiat Oncol Biol Phys 91, no. 3 (March 1, 2015): 564–70. https://doi.org/10.1016/j.ijrobp.2014.10.054.
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    • Zhao, Fen, Minghuan Li, Zhiheng Wang, Zheng Fu, Yunfeng Cui, Zhaoqiu Chen, and Jinming Yu. “(18)F-Fluorothymidine PET-CT for resected malignant gliomas before radiotherapy: tumor extent according to proliferative activity compared with MRI.” Plos One 10, no. 3 (2015): e0118769. https://doi.org/10.1371/journal.pone.0118769.
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    • Bar-Ad, Voichita, Benjamin Leiby, Matthew Witek, Ying Xiao, Yunfeng Cui, Yang Dai, Junsheng Cao, et al. “Treatment-related acute esophagitis for patients with locoregionally advanced non-small cell lung cancer treated with involved-field radiotherapy and concurrent chemotherapy.” Am J Clin Oncol 37, no. 5 (October 2014): 433–37. https://doi.org/10.1097/COC.0b013e31827de7a2.
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    • Zhao, Fen, Yunfeng Cui, Minghuan Li, Zheng Fu, Zhaoqiu Chen, Li Kong, Guoren Yang, and Jinming Yu. “Prognostic value of 3'-deoxy-3'-18F-fluorothymidine ([(18)F] FLT PET) in patients with recurrent malignant gliomas.” Nucl Med Biol 41, no. 8 (September 2014): 710–15. https://doi.org/10.1016/j.nucmedbio.2014.04.134.
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    • Cui, Y., J. Bowsher, S. Yan, J. Cai, S. Das, and F. Yin. “SU-C-9A-06: The Impact of CT Image Used for Attenuation Correction in 4D-PET.” Med Phys 41, no. 6 (June 2014): 105. https://doi.org/10.1118/1.4887847.
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    • Gardner, S., M. Studenski, T. Giaddui, Y. Cui, J. Galvin, Y. Yu, and Y. Xiao. “SU-E-J-152: Evaluation of TrueBeam OBI V. 1.5 CBCT Performance in An Adaptive RT Environment.” Med Phys 41, no. 6 (June 2014): 191. https://doi.org/10.1118/1.4888205.
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    • Giaddui, T., Y. Cui, W. Chen, J. Yu, Y. Gong, T. Craig, L. Dawson, et al. “SU-E-CAMPUS-J-04: Image Guided Radiation Therapy (IGRT): Review of Technical Standards and Credentialing in Radiotherapy Clinical Trials.” Med Phys 41, no. 6 (June 2014): 387. https://doi.org/10.1118/1.4889024.
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    • Gardner, Stephen J., Matthew T. Studenski, Tawfik Giaddui, Yunfeng Cui, James Galvin, Yan Yu, and Ying Xiao. “Investigation into image quality and dose for different patient geometries with multiple cone-beam CT systems.” Med Phys 41, no. 3 (March 2014): 031908. https://doi.org/10.1118/1.4865788.
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    • Wang, Jiazhou, Wenzhou Chen, Matthew Studenski, Yunfeng Cui, Andrew J. Lee, and Ying Xiao. “A semi-automated tool for treatment plan-quality evaluation and clinical trial quality assurance.” Phys Med Biol 58, no. 13 (July 7, 2013): N181–87. https://doi.org/10.1088/0031-9155/58/13/N181.
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    • Giaddui, T., Y. Cui, J. Galvin, Y. Yu, and Y. Xiao. “SU-E-I-07: The Effect of Different Beam Filters On the KV CBCT Image Dose Response Curves of NanoDot OSL Dosimeters.” Med Phys 40, no. 6Part4 (June 2013): 126. https://doi.org/10.1118/1.4814107.
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    • Giaddui, T., Y. Cui, J. Galvin, Y. Yu, and Y. Xiao. “SU-E-I-09: Measurements of KV XVI CBCT Dose Profiles in Phantom Using Gafchromic XRQA2 Film.” Med Phys 40, no. 6Part5 (June 2013): 126–27. https://doi.org/10.1118/1.4814109.
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    • Giaddui, Tawfik, Yunfeng Cui, James Galvin, Yan Yu, and Ying Xiao. “Comparative dose evaluations between XVI and OBI cone beam CT systems using Gafchromic XRQA2 film and nanoDot optical stimulated luminescence dosimeters.” Med Phys 40, no. 6 (June 2013): 062102. https://doi.org/10.1118/1.4803466.
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    • Giaddui, T., Y. Cui, J. Galvin, Y. Yu, and Y. Xiao. “Surface dose measurements of kV XVI cone-beam CT system using NanoDot optical stimulated luminescence dosimeters.” Ifmbe Proceedings 39 IFMBE (April 16, 2013): 1195–98. https://doi.org/10.1007/978-3-642-29305-4_313.
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    • Cui, Yunfeng, James M. Galvin, William Parker, Stephen Breen, Fang-Fang Yin, Jing Cai, Lech S. Papiez, et al. “Implementation of remote 3-dimensional image guided radiation therapy quality assurance for radiation therapy oncology group clinical trials.” Int J Radiat Oncol Biol Phys 85, no. 1 (January 1, 2013): 271–77. https://doi.org/10.1016/j.ijrobp.2012.03.002.
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    • Wang, J., W. Chen, M. Studenski, Y. Cui, A. Lee, and Y. Xiao. “SU‐E‐T‐234: An Automated Tool for Treatment Plan Quality Evaluation and Clinical Trial Quality Assurance.” Medical Physics 40, no. 6 (January 1, 2013): 258. https://doi.org/10.1118/1.4814669.
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    • Chen, Wenzhou, Yunfeng Cui, Yanyan He, Yan Yu, James Galvin, Yousuff M. Hussaini, and Ying Xiao. “Application of Dempster-Shafer theory in dose response outcome analysis.” Phys Med Biol 57, no. 17 (September 7, 2012): 5575–85. https://doi.org/10.1088/0031-9155/57/17/5575.
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    • Cao, Junsheng, Yunfeng Cui, Colin E. Champ, Haisong Liu, Ying Xiao, Maria Werner-Wasik, and Yan Yu. “Determination of internal target volume using selective phases of a 4-dimensional computed tomography scan.” Pract Radiat Oncol 2, no. 3 (July 2012): 186–92. https://doi.org/10.1016/j.prro.2011.09.004.
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    • Giaddui, T., Y. Cui, Z. Yegingil, J. Xie, W. Chen, J. Galvin, Y. Yu, and Y. Xiao. “SU-E-I-08: KV XVI Cone Beam-CT Dose Measurement Using Gafchromic XRQA2 Film.” Med Phys 39, no. 6Part4 (June 2012): 3626. https://doi.org/10.1118/1.4734722.
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    • Xie, J., W. Chen, Y. Cui, T. Giaddui, J. Galvin, Y. Yu, and Y. Xiao. “SU-E-T-284: Surface Dose Evaluation for Beams with and without Flattening Filter in Breast Cancer Treatment.” Med Phys 39, no. 6Part14 (June 2012): 3768–69. https://doi.org/10.1118/1.4735352.
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    • Yegingil, Z., Y. Cui, T. Giaddui, W. Chen, J. Xie, Y. Xiao, and Y. Yu. “SU-E-J-50: Measurement of the HVL Value for the 120keV Photon Beam of the X-Ray Volume Imager (XVI) Using Ionization Chamber, Gafchromic Film XRQA2 and Diode.” Med Phys 39, no. 6Part6 (June 2012): 3663. https://doi.org/10.1118/1.4734885.
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    • Giaddui, Tawfik, Yunfeng Cui, James Galvin, Wenzhou Chen, Yan Yu, and Ying Xiao. “Characteristics of Gafchromic XRQA2 films for kV image dose measurement.” Med Phys 39, no. 2 (February 2012): 842–50. https://doi.org/10.1118/1.3675398.
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    • Cui, Y., J. M. Galvin, W. Parker, S. L. Breen, F. Yin, L. S. Papiez, A. Li, G. Bednarz, W. Chen, and Y. Xiao. “Process and Initial Experience of Remote Credentialing of 3D IGRT Data for Institutions Participating in RTOG Clinical Trials.” International Journal of Radiation Oncology*Biology*Physics 81, no. 2 (October 2011): S810–S810. https://doi.org/10.1016/j.ijrobp.2011.06.1424.
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    • Cui, Yunfeng, James M. Galvin, William L. Straube, Walter R. Bosch, James A. Purdy, X Allen Li, and Ying Xiao. “Multi-system verification of registrations for image-guided radiotherapy in clinical trials.” Int J Radiat Oncol Biol Phys 81, no. 1 (September 1, 2011): 305–12. https://doi.org/10.1016/j.ijrobp.2010.11.019.
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    • Cao, J., Y. Cui, M. Werner‐wasik, C. Champ, H. Liu, Y. Xiao, and Y. yu. “SU‐E‐T‐291: How Many Sets of Four‐Dimensional Computed Tomography (4DCT) Images Are Needed to Determine the Internal Target Volume (ITV) for Lung Radiation Therapy?” Medical Physics 38, no. 6 (January 1, 2011): 3554. https://doi.org/10.1118/1.3612242.
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    • Xiao, Y., Y. Cui, W. Chen, Y. Yu, J. Galvin, and M. Y. Hussaini. “Application of evidence theory in radiation oncology outcome analysis.” Proceedings  2010 3rd International Conference on Biomedical Engineering and Informatics, Bmei 2010 5 (December 1, 2010): 1985–87. https://doi.org/10.1109/BMEI.2010.5639437.
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    • Cui, Yunfeng, Yongqiang Tan, Binsheng Zhao, Laura Liberman, Rakesh Parbhu, Jennifer Kaplan, Maria Theodoulou, Clifford Hudis, and Lawrence H. Schwartz. “Malignant lesion segmentation in contrast-enhanced breast MR images based on the marker-controlled watershed.” Med Phys 36, no. 10 (October 2009): 4359–69. https://doi.org/10.1118/1.3213514.
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    • Cui, Y., B. Zhao, T. J. Akhurst, J. Yan, and L. H. Schwartz. “CT-guided, automated detection of lung tumors on PET images.” Progress in Biomedical Optics and Imaging  Proceedings of Spie 6915 (June 2, 2008). https://doi.org/10.1117/12.770549.
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    • Cui, Y., J. Bai, Y. Chen, and J. Tian. “Kinetic model parameter estimates of liver FDG metabolism.” Qinghua Daxue Xuebao/Journal of Tsinghua University 47, no. 3 (March 1, 2007): 420–23.
    • Cui, Y., J. Bai, Y. Chen, and J. Tian. “A digital model framework of metabolic system based on visible human data set.” International Journal of Image and Graphics 7, no. 1 (January 1, 2007): 143–57. https://doi.org/10.1142/S0219467807002593.
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    • Cui, Y., J. Bai, Y. Chen, and J. Tian. “Parameter estimation for whole-body kinetic model of FDG metabolism.” Progress in Natural Science: Materials International 16, no. 11 (January 1, 2006): 1164–70. https://doi.org/10.1080/10020070612330124.
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    • Yunfeng, C., and B. Jing. “Comparison of parameter estimations using dual-input and arterial-input in liver kinetic studies of FDG metabolism.” Annual International Conference of the Ieee Engineering in Medicine and Biology  Proceedings 7 VOLS (December 1, 2005): 2345–48.
    • Cui, Y., and J. Bai. “Method of simulation and visualization of FDG metabolism based on VHP image.” Progress in Biomedical Optics and Imaging  Proceedings of Spie 5744, no. II (August 16, 2005): 547–54. https://doi.org/10.1117/12.593312.
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  • Conference Papers

    • Wang, C., Y. Xie, Z. Hu, F. F. Yin, Z. Reitman, and Y. Cui. “A Dosimetric Study Comparing Two Beam Arrangement Strategies in Fractionated Thoracic Spine Stereotactic Body Radiotherapy (SBRT) Planning.” In International Journal of Radiation Oncology, Biology, Physics, 111:e557, 2021. https://doi.org/10.1016/j.ijrobp.2021.07.1510.
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    • Kent, C. L., J. C. Hong, C. N. Rushing, A. M. Faught, Y. Cui, F. F. Yin, B. Czito, C. G. Willett, and M. Palta. “Association of Interim FDG-PET During Chemoradiation for Anal Squamous Cell Carcinoma with Recurrence: An Updated Analysis.” In International Journal of Radiation Oncology Biology Physics, 108:E584–E584, 2020.
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    • Cui, Y., A. Rodrigues, S. Yoo, and F. Yin. “Retrospective Review of Machine Quality Assurance Results of a PET-CT Simulator.” In Medical Physics, 47:E845–E845, 2020.
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    • Li, X., J. Zhang, Y. Sheng, K. Lafata, N. Eclov, Y. Cui, W. Giles, et al. “A Machine Learning Model for Brain V12 Gy/V60% Prediction of LINAC-Based Single-Iso-Multiple-Targets (SIMT) Stereotactic Radiosurgery (SRS): A Longitudinal Study.” In Medical Physics, 47:E568–69, 2020.
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    • Rodrigues, A., J. O’Daniel, Y. Mowery, F. Yin, and Y. Cui. “Failure Mode and Effects Analysis for PET Applications in Radiation Therapy Quality Management.” In Medical Physics, 47:E780–E780, 2020.
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    • Chang, Y., C. Liu, K. Lafata, C. Wang, Y. Cui, L. Ren, Y. M. Mowery, D. M. Brizel, and F. F. Yin. “PET Radiotherapy Response Assessment Using Encoder-Decoder Convolutional Neural Network and Pre-treatment Information: A Feasibility of Oropharynx Cancer IMRT.” In International Journal of Radiation Oncology*Biology*Physics, 105:E413–E413. Elsevier BV, 2019. https://doi.org/10.1016/j.ijrobp.2019.06.1615.
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    • Wang, C., C. Liu, K. Lafata, Y. Chang, Y. Cui, X. Li, Y. M. Mowery, D. M. Brizel, and F. F. Yin. “Dose-Distribution-Driven PET Image-based Outcome Prediction (DDD-PIOP): A Framework Design for Oropharyngeal Cancer IMRT Application.” In International Journal of Radiation Oncology*Biology*Physics, 105:S81–82. Elsevier BV, 2019. https://doi.org/10.1016/j.ijrobp.2019.06.546.
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    • Chang, Y., K. Lafata, C. Liu, C. Wang, Y. Cui, L. Ren, X. Li, Y. Mowery, D. Brizel, and F. Yin. “An Encoder-Decoder Based Convolutional Neural Network (ED-CNN) for PET Image Response Prediction Using Pre-RT Information: A Feasibility of Oropharynx Cancer IMRT.” In Medical Physics, 46:E283–E283. WILEY, 2019.
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    • Liu, C., C. Wang, K. Lafata, Y. Chang, Y. Cui, and F. Yin. “Dose-Specific PET Image-Based Outcome Prediction: A Deep Learning Study for Oropharyngeal Cancer IMRT Application.” In Medical Physics, 46:E525–E525. WILEY, 2019.
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    • Sheng, Y., Y. Cui, S. Elguindi, J. Kirkpatrick, F. Yin, and E. Subashi. “Dosimetric Impact of Residual Distortion in a 3T MR Simulator Used for Stereotactic Radiosurgery Treatment Planning.” In Medical Physics, 46:E391–E391. WILEY, 2019.
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    • Cui, Y., H. Gao, J. P. Kirkpatrick, and F. F. Yin. “A Retrospective Review on Stereotactic Radiosurgery Cases Planned with Dynamic Conformal Arcs Versus Volumetric Modulated Arc Therapy.” In International Journal of Radiation Oncology*Biology*Physics, 102:e211–12. Elsevier BV, 2018. https://doi.org/10.1016/j.ijrobp.2018.07.740.
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    • Subashi, E. D., Z. Wang, Y. Cui, Z. Chang, J. P. Kirkpatrick, and F. F. Yin. “An Analysis of Geometric Distortion in a 3T MRI Scanner Used for Intracranial Radiosurgery.” In International Journal of Radiation Oncology*Biology*Physics, 102:e518–e518. Elsevier BV, 2018. https://doi.org/10.1016/j.ijrobp.2018.07.1462.
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    • Cui, Y., H. Gao, J. Kirkpatrick, and F. Yin. “Variation in Normal Brain Sparing in Stereotactic Radiosurgery Plans Treating Multiple Targets Using Single-Isocenter Volumetric Modulated Arc Therapy.” In Medical Physics, 45:E191–E191. WILEY, 2018.
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    • Gao, H., R. Liu, H. Yu, Y. Cui, Z. Chang, and F. Yin. “Iterative Katsevich Algorithm: A Novel Iterative Image Reconstruction Method for Helical CT Using Katsevich Exact Analytic Algorithm.” In Medical Physics, 45:E167–E167. WILEY, 2018.
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    • Tandberg, D. J., Y. Cui, J. C. Hong, B. Ackerson, B. Czito, C. G. Willett, and M. Palta. “Intratreatment FDG-PET Imaging to Predict Radiation Induced Esophagitis During Chemoradiation Therapy for Esophageal Cancer.” In International Journal of Radiation Oncology*Biology*Physics, 99:E189–E189. Elsevier BV, 2017. https://doi.org/10.1016/j.ijrobp.2017.06.1055.
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    • Tandberg, Daniel, Julian C. Hong, Yunfeng Cui, Brad Ackerson, Brian G. Czito, Christopher Willett, and Manisha Palta. “Interim FDG-PET imaging during neoadjuvant chemoradiotherapy for esophageal cancer: Correlation with pathologic response.” In Journal of Clinical Oncology, 35:175–175. American Society of Clinical Oncology (ASCO), 2017. https://doi.org/10.1200/jco.2017.35.4_suppl.175.
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    • Cui, Y., J. Bowsher, J. Cai, and F. F. Yin. “Evaluation of Respiratory Motion Impact on 3D and 4D PET Imaging.” In International Journal of Radiation Oncology*Biology*Physics, 93:E553–E553. Elsevier BV, 2015. https://doi.org/10.1016/j.ijrobp.2015.07.1963.
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    • Giaddui, T., Y. Cui, W. Chen, J. Yu, Y. Gong, T. Craig, L. Dawson, et al. “Image Guided Radiation Therapy (IGRT): Review of Technical Standards and Credentialing in Radiotherapy Clinical Trials.” In Medical Physics, 41:387–387. WILEY, 2014.
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    • Cui, Y., W. Chen, F. Kong, L. Appenzoller, R. Beatty, P. Maxim, T. Ritter, et al. “TH‐A‐BRA‐01: Contouring Variations and Their Impact on Dose‐Volume Histograms in Non‐Small‐Cell Lung Cancer Radiotherapy: Analysis of a Multi‐ Institutional Pre‐Clinical Trial Planning Study.” In Medical Physics, 39:3983, 2012. https://doi.org/10.1118/1.4736250.
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    • Cui, Y., T. Giaddui, J. Galvin, W. Chen, Y. yu, and Y. Xiao. “MO‐F‐110‐03: Reference Dosimetry of New GafChromic XR‐QA2 Model for Kilovoltage Imaging Dose Using Ion Chamber and Flat‐Bed Document Scanner.” In Medical Physics, 38:3727–28, 2011. https://doi.org/10.1118/1.3613025.
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    • Giaddui, T., Y. Cui, J. Galvin, W. Chen, Y. yu, Y. Xiao, and T. Jefferson. “SU‐E‐I‐53: On the Characterization and the Characteristics of the GafChromic XRQA2 Radiochromic Films.” In Medical Physics, 38:3408, 2011. https://doi.org/10.1118/1.3611626.
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