Current Duke Appointments & Affiliations
Assistant Professor in Surgery
·
2021 - Present
Surgery, Surgical Sciences,
Surgery
Assistant Professor of Pathology
·
2022 - Present
Pathology,
Clinical Science Departments
Member of the Duke Cancer Institute
·
2022 - Present
Duke Cancer Institute,
Institutes and Centers
Recent Scholarly Works
Prognostic Implications of Codon-Specific KRAS Mutations in Localized and Advanced Stages of Pancreatic Cancer.
Journal article JCO Precis Oncol · February 2026 PURPOSE: Although KRAS mutations represent the primary oncogenic driver in pancreatic ductal adenocarcinoma (PDAC), the association between codon-specific alterations and patient outcomes remains poorly elucidated, largely because of a lack of data sets co ... Full text Link to item CiteLoss of inducible nitric oxide synthase promotes Kras/Pten-driven lung tumorigenesis.
Journal article Front Cell Dev Biol · 2026 The inducible Nitric Oxide Synthase (iNOS) enzyme has been implicated in both pro- and anti-tumorigenic processes, depending on the cancer context. In oncogenic Kras-driven mouse models of lung adenocarcinoma, the loss of iNOS reduces tumorigenesis. To exp ... Full text Link to item CiteExploiting codon usage identifies intensity-specific modifiers of Ras/MAPK signaling in vivo.
Journal article PLoS Genet · December 2020 Signal transduction pathways are intricately fine-tuned to accomplish diverse biological processes. An example is the conserved Ras/mitogen-activated-protein-kinase (MAPK) pathway, which exhibits context-dependent signaling output dynamics and regulation. ... Full text Link to item CiteRecent Grants
Dynamic requirements of Ras signaling during cancer
ResearchPostdoctoral Associate · Awarded by National Institutes of Health · 2014 - 2019View All Grants
Education
National University of Singapore (Singapore) ·
2014
Ph.D.
National University of Singapore (Singapore) ·
2010
M.S.
Isfahan University (Iran) ·
2007
M.D.