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Michael Rod Zalutsky

Jonathan Spicehandler, M.D. Distinguished Professor of Neuro Oncology, in the School of Medicine
Radiology
Box 3808 Med Ctr, Durham, NC 27710
311 Research Drive, 161H Bryan Res Bldg, Durham, NC 27710

Scholarly Works - Book sections


The Radiopharmaceutical Chemistry of the Halogen Radionuclides

Book section · January 1, 2023 Radiohalogens are far fewer in number than radiometals, yet they have been important in radiopharmaceutical therapy since the very beginning. Indeed, radionuclides of the three heaviest naturally occurring halogens-bromine, iodine, and astatine-provide rad ... Full text Cite

Small Molecules as Vectors for Radiopharmaceutical Therapy

Book section · January 1, 2023 Radiopharmaceutical therapy (RPT) with small molecule-based agents is already a standard-of-care in multiple clinical scenarios, including patients with metastatic, castration-resistant prostate cancer whose tumors express prostate-specific membrane antige ... Full text Cite

The Radiopharmaceutical Chemistry of the Radioisotopes of Iodine

Book section · January 1, 2019 Radioisotopes of iodine have been incorporated into a wide variety of radiopharmaceuticals ranging from small, low molecular weight compounds to large molecules like antibodies. Because of the routine availability of radioisotopes of iodine with different ... Full text Cite

Monoclonal Antibodies

Book section · January 1, 2007 Over the last decades, progress has been made in diagnostic imaging, surgical techniques, radiotherapy, and chemotherapy for the treatment of tumors of the central nervous system. However, the outcome for patients with high-grade gliomas (HGG) has remained ... Full text Cite

Radiohalogens for radioimmunotherapy

Book section · January 1, 2000 The selective delivery of cytotoxic radionuclides to malignant cell populations is the central objective of radioimmunotherapy. The impact of radioimmunotherapy on the clinical management of cancer has generally been limited, particularly for the treatment ... Cite