Scholars@Duke
Yi Zeng

Yi Zeng

Professor in Medicine
Medicine, Geriatrics and Palliative Care
zengyi@duke.edu
Duke Box 3003, Durham, NC 27710
Room 1506, Duke South, Durham, NC 27710
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Selected Publications

Development and Validation of the Disability Index Among Older Adults.

Journal Article J Gerontol A Biol Sci Med Sci · January 26, 2023 BACKGROUND: With the rapid population aging, the challenge to provide care for disabled older adults is becoming bigger. This study aims to develop the Disability Index (DI) to assess disability to indicate care needs, and we evaluated the reliability and ... Full text Open Access Link to item Cite

Comparing Effects of FOXO3 and Residing in Urban Areas on Longevity: A Gene-Environment Interaction Study.

Journal Article J Gerontol A Biol Sci Med Sci · August 12, 2022 Forkhead box O3 (FOXO3) is a candidate longevity gene. Urban residents are also positively associated with longer life expectancy. We conducted a gene-environment interaction to assess the synergistic effect of FOXO3 and urban/rural environments on mortali ... Full text Link to item Cite

Sex Difference and Interaction of SIRT1 and FOXO3 Candidate Longevity Genes on Life Expectancy: A 10-Year Prospective Longitudinal Cohort Study.

Journal Article J Gerontol A Biol Sci Med Sci · August 12, 2022 SIRT1 and FOXO3 are both associated with longevity. Molecular biology research in many organisms (yeast, nematode worm Caenorhabditis elegans, and mice mammalian models) shows SIRT1 acts on the FOXO family of forkhead transcription factors to respond to ox ... Full text Link to item Cite

Effect of FOXO3 and Air Pollution on Cognitive Function: A Longitudinal Cohort Study of Older Adults in China From 2000 to 2014.

Journal Article J Gerontol A Biol Sci Med Sci · August 12, 2022 Forkhead Box O 3 (FOXO3) genotype is strongly associated with human longevity and may be protective against neurodegeneration. Air pollution is a risk factor for cognitive decline and dementia. We aimed to study the individual and combined effects of FOXO3 ... Full text Link to item Cite

Interaction between plant-based dietary pattern and air pollution on cognitive function: a prospective cohort analysis of Chinese older adults.

Journal Article Lancet Reg Health West Pac · March 2022 BACKGROUND: Air pollution is a risk factor for poor cognitive function, while a plant-based dietary pattern is associated with better cognitive function. We aimed to explore their interaction with cognitive function among older adults. METHODS: We used a p ... Full text Link to item Cite

Effect of heatwaves and greenness on mortality among Chinese older adults.

Journal Article Environ Pollut · December 1, 2021 Heatwaves and greenness have been shown to affect health, but the evidence on their joint effects is limited. We aim to assess the associations of the combined exposure to greenness and heatwaves. We utilized five waves (February 2000-October 2014) of the ... Full text Link to item Cite

Impacts of family household dynamics on residential energy demands in Hebei Province of China

Journal Article Genus · December 1, 2021 This article presents analyses and projections of the residential energy demands in Hebei Province of China, using the ProFamy extended cohort-component method and user-friendly free software and conventional demographic data as input. The results indicate ... Full text Cite

Identification and replication of novel genetic variants of ABO gene to reduce the incidence of diseases and promote longevity by modulating lipid homeostasis.

Journal Article Aging (Albany NY) · November 22, 2021 Genes related to human longevity have not been studied so far, and need to be investigated thoroughly. This study aims to explore the relationship among ABO gene variants, lipid levels, and longevity phenotype in individuals (≥90yrs old) without adverse ou ... Full text Link to item Cite

Interaction of greenness and polygenic risk score of Alzheimer's disease on risk of cognitive impairment.

Journal Article Sci Total Environ · November 20, 2021 Studies have shown contact with nature has positive psychological, neurological, and cognitive benefits. Whether the built environment can affect genetic predisposition of Alzheimer's disease (AD) should be explored. We aimed to examine whether greenness a ... Full text Link to item Cite

Sleep duration, vegetable consumption and all-cause mortality among older adults in China: a 6-year prospective study.

Journal Article BMC Geriatr · June 21, 2021 BACKGROUND: Sleep duration and vegetable consumption are associated with mortality at old age (termed as sleep-mortality linkage and vegetable-mortality linkage, respectively). Yet, little is known about the interplay of sleep duration and vegetable consum ... Full text Link to item Cite

Association of APOE ε4 genotype and lifestyle with cognitive function among Chinese adults aged 80 years and older: A cross-sectional study.

Journal Article PLoS Med · June 2021 BACKGROUND: Apolipoprotein E (APOE) ε4 is the single most important genetic risk factor for cognitive impairment and Alzheimer disease (AD), while lifestyle factors such as smoking, drinking, diet, and physical activity also have impact on cognition. The g ... Full text Link to item Cite

Type of tea consumption and depressive symptoms in Chinese older adults.

Journal Article BMC Geriatr · May 24, 2021 BACKGROUND: Existing research indicates that tea drinking may exert beneficiary effects on mental health. However, associations between different types of tea intake and mental health such as depression have not been fully examined. The purpose of this stu ... Full text Link to item Cite

Interaction between APOE ε4 and dietary protein intake on cognitive decline: A longitudinal cohort study.

Journal Article Clin Nutr · May 2021 OBJECTIVE: To exam the association of cognitive decline with APOE ε4 allele carriage and dietary protein intake and investigate whether there is a gene-diet (GxD) interaction of APOE ε4 allele carriage and dietary protein intake on cognitive decline in a n ... Full text Link to item Cite

Residential proximity to major roadways and cognitive function among Chinese adults 65 years and older.

Journal Article Sci Total Environ · April 20, 2021 Emerging evidence in North America and Europe suggests that traffic-related air pollution (TRAP) adversely affects cognition. However, little is known about this relationship in people living in low- and middle-income countries (LMICs). It is also unknown ... Full text Link to item Cite

Interaction of Sirtuin 1 (SIRT1) candidate longevity gene and particulate matter (PM2.5) on all-cause mortality: a longitudinal cohort study in China.

Journal Article Environ Health · March 14, 2021 BACKGROUND: The SIRT1 gene was associated with the lifespan in several organisms through inflammatory and oxidative stress pathways. Long-term air particulate matter (PM) is detrimental to health through the same pathways. METHODS: We used the Chinese Long ... Full text Link to item Cite

Integrated genetic analyses revealed novel human longevity loci and reduced risks of multiple diseases in a cohort study of 15,651 Chinese individuals.

Journal Article Aging Cell · March 2021 There is growing interest in studying the genetic contributions to longevity, but limited relevant genes have been identified. In this study, we performed a genetic association study of longevity in a total of 15,651 Chinese individuals. Novel longevity lo ... Full text Link to item Cite

Gene-Environment Interaction of FOXO and Residential Greenness on Mortality Among Older Adults.

Journal Article Rejuvenation Res · February 2021 Residential greenness is an important environmental factor that is strongly associated with mortality. To our knowledge, there was no previous study on the gene-environment interaction analysis between residential greenness and forkhead box O (FOXO) gene, ... Full text Link to item Cite

Apolipoprotein E Genotype, Meat, Fish, and Egg Intake in Relation to Mortality Among Older Adults: A Longitudinal Analysis in China.

Journal Article Front Med (Lausanne) · 2021 Introduction: The interactions between apolipoprotein E (APOE) genotype and diet pattern changes were found significant in several trials, implying that APOE gene may modify the effect of animal protein-rich food on health outcomes. We aim to study the int ... Full text Link to item Cite

Apolipoprotein E Induced Cognitive Dysfunction: Mediation Analysis of Lipids and Glucose Biomarkers in an Elderly Cohort Study.

Journal Article Front Aging Neurosci · 2021 INTRODUCTION: Prior evidence suggested Apolipoprotein E (APOE), lipids, and glucose metabolism may act through the same pathways on the pathogenesis of Alzheimer's disease (AD). METHODS: This prospective study used data from the Chinese Longitudinal Health ... Full text Link to item Cite

Development and Validation of the Disability Index Among Older Adults.

Journal Article J Gerontol A Biol Sci Med Sci · January 26, 2023 BACKGROUND: With the rapid population aging, the challenge to provide care for disabled older adults is becoming bigger. This study aims to develop the Disability Index (DI) to assess disability to indicate care needs, and we evaluated the reliability and ... Full text Open Access Link to item Cite

Comparing Effects of FOXO3 and Residing in Urban Areas on Longevity: A Gene-Environment Interaction Study.

Journal Article J Gerontol A Biol Sci Med Sci · August 12, 2022 Forkhead box O3 (FOXO3) is a candidate longevity gene. Urban residents are also positively associated with longer life expectancy. We conducted a gene-environment interaction to assess the synergistic effect of FOXO3 and urban/rural environments on mortali ... Full text Link to item Cite

Sex Difference and Interaction of SIRT1 and FOXO3 Candidate Longevity Genes on Life Expectancy: A 10-Year Prospective Longitudinal Cohort Study.

Journal Article J Gerontol A Biol Sci Med Sci · August 12, 2022 SIRT1 and FOXO3 are both associated with longevity. Molecular biology research in many organisms (yeast, nematode worm Caenorhabditis elegans, and mice mammalian models) shows SIRT1 acts on the FOXO family of forkhead transcription factors to respond to ox ... Full text Link to item Cite

Effect of FOXO3 and Air Pollution on Cognitive Function: A Longitudinal Cohort Study of Older Adults in China From 2000 to 2014.

Journal Article J Gerontol A Biol Sci Med Sci · August 12, 2022 Forkhead Box O 3 (FOXO3) genotype is strongly associated with human longevity and may be protective against neurodegeneration. Air pollution is a risk factor for cognitive decline and dementia. We aimed to study the individual and combined effects of FOXO3 ... Full text Link to item Cite

Interaction between plant-based dietary pattern and air pollution on cognitive function: a prospective cohort analysis of Chinese older adults.

Journal Article Lancet Reg Health West Pac · March 2022 BACKGROUND: Air pollution is a risk factor for poor cognitive function, while a plant-based dietary pattern is associated with better cognitive function. We aimed to explore their interaction with cognitive function among older adults. METHODS: We used a p ... Full text Link to item Cite

Effect of heatwaves and greenness on mortality among Chinese older adults.

Journal Article Environ Pollut · December 1, 2021 Heatwaves and greenness have been shown to affect health, but the evidence on their joint effects is limited. We aim to assess the associations of the combined exposure to greenness and heatwaves. We utilized five waves (February 2000-October 2014) of the ... Full text Link to item Cite

Impacts of family household dynamics on residential energy demands in Hebei Province of China

Journal Article Genus · December 1, 2021 This article presents analyses and projections of the residential energy demands in Hebei Province of China, using the ProFamy extended cohort-component method and user-friendly free software and conventional demographic data as input. The results indicate ... Full text Cite

Identification and replication of novel genetic variants of ABO gene to reduce the incidence of diseases and promote longevity by modulating lipid homeostasis.

Journal Article Aging (Albany NY) · November 22, 2021 Genes related to human longevity have not been studied so far, and need to be investigated thoroughly. This study aims to explore the relationship among ABO gene variants, lipid levels, and longevity phenotype in individuals (≥90yrs old) without adverse ou ... Full text Link to item Cite

Interaction of greenness and polygenic risk score of Alzheimer's disease on risk of cognitive impairment.

Journal Article Sci Total Environ · November 20, 2021 Studies have shown contact with nature has positive psychological, neurological, and cognitive benefits. Whether the built environment can affect genetic predisposition of Alzheimer's disease (AD) should be explored. We aimed to examine whether greenness a ... Full text Link to item Cite

Sleep duration, vegetable consumption and all-cause mortality among older adults in China: a 6-year prospective study.

Journal Article BMC Geriatr · June 21, 2021 BACKGROUND: Sleep duration and vegetable consumption are associated with mortality at old age (termed as sleep-mortality linkage and vegetable-mortality linkage, respectively). Yet, little is known about the interplay of sleep duration and vegetable consum ... Full text Link to item Cite

Association of APOE ε4 genotype and lifestyle with cognitive function among Chinese adults aged 80 years and older: A cross-sectional study.

Journal Article PLoS Med · June 2021 BACKGROUND: Apolipoprotein E (APOE) ε4 is the single most important genetic risk factor for cognitive impairment and Alzheimer disease (AD), while lifestyle factors such as smoking, drinking, diet, and physical activity also have impact on cognition. The g ... Full text Link to item Cite

Type of tea consumption and depressive symptoms in Chinese older adults.

Journal Article BMC Geriatr · May 24, 2021 BACKGROUND: Existing research indicates that tea drinking may exert beneficiary effects on mental health. However, associations between different types of tea intake and mental health such as depression have not been fully examined. The purpose of this stu ... Full text Link to item Cite

Interaction between APOE ε4 and dietary protein intake on cognitive decline: A longitudinal cohort study.

Journal Article Clin Nutr · May 2021 OBJECTIVE: To exam the association of cognitive decline with APOE ε4 allele carriage and dietary protein intake and investigate whether there is a gene-diet (GxD) interaction of APOE ε4 allele carriage and dietary protein intake on cognitive decline in a n ... Full text Link to item Cite

Residential proximity to major roadways and cognitive function among Chinese adults 65 years and older.

Journal Article Sci Total Environ · April 20, 2021 Emerging evidence in North America and Europe suggests that traffic-related air pollution (TRAP) adversely affects cognition. However, little is known about this relationship in people living in low- and middle-income countries (LMICs). It is also unknown ... Full text Link to item Cite

Interaction of Sirtuin 1 (SIRT1) candidate longevity gene and particulate matter (PM2.5) on all-cause mortality: a longitudinal cohort study in China.

Journal Article Environ Health · March 14, 2021 BACKGROUND: The SIRT1 gene was associated with the lifespan in several organisms through inflammatory and oxidative stress pathways. Long-term air particulate matter (PM) is detrimental to health through the same pathways. METHODS: We used the Chinese Long ... Full text Link to item Cite

Integrated genetic analyses revealed novel human longevity loci and reduced risks of multiple diseases in a cohort study of 15,651 Chinese individuals.

Journal Article Aging Cell · March 2021 There is growing interest in studying the genetic contributions to longevity, but limited relevant genes have been identified. In this study, we performed a genetic association study of longevity in a total of 15,651 Chinese individuals. Novel longevity lo ... Full text Link to item Cite

Gene-Environment Interaction of FOXO and Residential Greenness on Mortality Among Older Adults.

Journal Article Rejuvenation Res · February 2021 Residential greenness is an important environmental factor that is strongly associated with mortality. To our knowledge, there was no previous study on the gene-environment interaction analysis between residential greenness and forkhead box O (FOXO) gene, ... Full text Link to item Cite

Apolipoprotein E Genotype, Meat, Fish, and Egg Intake in Relation to Mortality Among Older Adults: A Longitudinal Analysis in China.

Journal Article Front Med (Lausanne) · 2021 Introduction: The interactions between apolipoprotein E (APOE) genotype and diet pattern changes were found significant in several trials, implying that APOE gene may modify the effect of animal protein-rich food on health outcomes. We aim to study the int ... Full text Link to item Cite

Apolipoprotein E Induced Cognitive Dysfunction: Mediation Analysis of Lipids and Glucose Biomarkers in an Elderly Cohort Study.

Journal Article Front Aging Neurosci · 2021 INTRODUCTION: Prior evidence suggested Apolipoprotein E (APOE), lipids, and glucose metabolism may act through the same pathways on the pathogenesis of Alzheimer's disease (AD). METHODS: This prospective study used data from the Chinese Longitudinal Health ... Full text Link to item Cite

Leisure Activities, APOE ε4, and Cognitive Decline: A Longitudinal Cohort Study.

Journal Article Front Aging Neurosci · 2021 Background: Both leisure activities and the ε4 allele of the apolipoprotein E (APOE ε4) have been shown to affect cognitive health. We aimed to determine whether engagement in leisure activities protects against APOE ε4-related cognitive decline. Methods: ... Full text Link to item Cite

Residential Greenness Alters Serum 25(OH)D Concentrations: A Longitudinal Cohort of Chinese Older Adults.

Journal Article J Am Med Dir Assoc · December 2020 OBJECTIVES: Vitamin D deficiency is prevalent among older adults. We aimed to study whether residential greenness could alter serum 25(OH)D concentrations as a possible mechanism of residential greenness's positive health effects. DESIGN: A longitudinal co ... Full text Link to item Cite

Genetic and non-genetic factors associated with the phenotype of exceptional longevity & normal cognition.

Journal Article Sci Rep · November 5, 2020 In this study, we split 2156 individuals from the Chinese Longitudinal Healthy Longevity Survey (CLHLS) data into two groups, establishing a phenotype of exceptional longevity & normal cognition versus cognitive impairment. We conducted a genome-wide assoc ... Full text Link to item Cite

Trends in the Incidence of Activities of Daily Living Disability Among Chinese Older Adults From 2002 to 2014.

Journal Article J Gerontol A Biol Sci Med Sci · October 15, 2020 BACKGROUND: Evidence of the trend of the incidence of activities of daily living (ADL) disability among Chinese older people is limited. We aimed to investigate the time trends and potential risk factors for the incidence of ADL disability among Chinese ol ... Full text Link to item Cite

Serum 25-Hydroxyvitamin D, Albumin, and Mortality Among Chinese Older Adults: A Population-based Longitudinal Study.

Journal Article J Clin Endocrinol Metab · August 1, 2020 CONTEXT: The associations between serum 25-hydroxyvitamin D concentrations [25(OH)D] and all-cause mortality have been inconsistent in existing literatures. One plausible reason is the interaction of intrinsic vitamin D with other biological conditions suc ... Full text Link to item Cite

Higher dietary diversity scores and protein-rich food consumption were associated with lower risk of all-cause mortality in the oldest old.

Journal Article Clin Nutr · July 2020 BACKGROUND & AIMS: Dietary diversity is widely advocated in national and international recommendations although whether the beneficial effects on survival or longevity still apply in the final phase of the lifespan remains understudied. We aimed to prospec ... Full text Link to item Cite

Physical Rehabilitation Needs in the BRICS Nations from 1990 to 2017: Cross-National Analyses Using Data from the Global Burden of Disease Study.

Journal Article Int J Environ Res Public Health · June 10, 2020 Background: This study analyzes the current and evolving physical rehabilitation needs of BRICS nations (Brazil, Russian Federation, India, China, South Africa), a coalition of large emergent economies increasingly important for global health. Methods: Sec ... Full text Link to item Cite

Trajectories of cognitive function and their determinants in older people: 12 years of follow-up in the Chinese Longitudinal Healthy Longevity Survey.

Journal Article Int Psychogeriatr · June 2020 BACKGROUND: Cognitive decline in advanced age is closely related to dementia. The trajectory of cognitive function in older Chinese is yet to be fully investigated. We aimed to investigate the trajectories of cognitive function in a nationally representati ... Full text Link to item Cite

Leisure Activities and All-Cause Mortality Among the Chinese Oldest-Old Population: A Prospective Community-Based Cohort Study.

Journal Article J Am Med Dir Assoc · June 2020 OBJECTIVE: To investigate associations between leisure activities, examining each activity separately and in combination, and all-cause mortality among the Chinese oldest-old (≥80 years) population. DESIGN: Prospective cohort study. SETTING: Community-livi ... Full text Link to item Cite

Number of natural teeth, denture use and mortality in Chinese elderly: a population-based prospective cohort study.

Journal Article BMC Oral Health · April 10, 2020 BACKGROUND: The associations between the number of natural teeth/denture use and all-cause mortality remain unclear due to lake of investigation for the potential interaction between tooth loss and denture use and for the potential changes in these exposur ... Full text Link to item Cite

Long-term exposure to PM2.5 and incidence of disability in activities of daily living among oldest old.

Journal Article Environ Pollut · April 2020 Currently the Chinese government has adopted World Health Organization interim target-1 values as the national ambient air quality standards values. However, the population-based evidence was insufficient, especially for the oldest old (aged 80+). We evalu ... Full text Link to item Cite

Forecast Households at the County Level: An Application of the ProFamy Extended Cohort-Component Method in Six Counties of Southern California, 2010 to 2040

Journal Article Population Research and Policy Review · April 1, 2020 Policymakers and market analysts have long been interested in future trends of households. Among household projection methods, the ProFamy extended cohortcomponent method, as one alternative to the traditional headship-rate method, has recently been extend ... Full text Cite

Specific Leisure Activities and Cognitive Functions Among the Oldest-Old: The Chinese Longitudinal Healthy Longevity Survey.

Journal Article J Gerontol A Biol Sci Med Sci · March 9, 2020 BACKGROUND: Little is known about the role of specific leisure activities in affecting cognitive functions. We aim to examine the associations of specific leisure activities with the risk of cognitive impairment among oldest-old people in China. METHODS: T ... Full text Link to item Cite

Association of cognitive impairment and elderly mortality: differences between two cohorts ascertained 6-years apart in China.

Journal Article BMC Geriatr · January 28, 2020 BACKGROUND: Cognitive impairment is a major contributor to mortality among the elderly. However, the relationship between cognitive impairment evaluated by educational levels and mortality and the trend between cognitive impairment and mortality with time ... Full text Link to item Cite

APOE ε4 Modifies Effect of Residential Greenness on Cognitive Function among Older Adults: A Longitudinal Analysis in China.

Journal Article Sci Rep · January 9, 2020 We tested whether the protective effects of residential greenness on cognitive function differ by APOE ε4 status by using the Chinese Longitudinal Healthy Longevity Survey (CLHLS). We calculated Normalized Difference Vegetation Index (NDVI) using 500 m rad ... Full text Link to item Cite

Late-Life Cognitive Trajectories and their Associated Lifestyle Factors.

Journal Article J Alzheimers Dis · 2020 Significant variability exists in the trajectories of late-life cognitive decline; however, their associated lifestyle factors remain less studied. We examined these trajectories among elderly participants from the recent five waves (at three-year interval ... Full text Link to item Cite

A meta-analysis of genome-wide association studies identifies multiple longevity genes.

Journal Article Nat Commun · August 14, 2019 Human longevity is heritable, but genome-wide association (GWA) studies have had limited success. Here, we perform two meta-analyses of GWA studies of a rigorous longevity phenotype definition including 11,262/3484 cases surviving at or beyond the age corr ... Full text Link to item Cite

Associations between superoxide dismutase, malondialdehyde and all-cause mortality in older adults: a community-based cohort study.

Journal Article BMC Geriatr · April 15, 2019 BACKGROUND: Oxidative stress is an important theory of aging but population-based evidence has been lacking. This study aimed to evaluate the associations between biomarkers of oxidative stress, including plasma superoxide dismutase (SOD) activity and malo ... Full text Open Access Link to item Cite

Triglycerides Paradox Among the Oldest Old: "The Lower the Better?".

Journal Article J Am Geriatr Soc · April 2019 OBJECTIVES: Currently, most treatment guidelines suggest lowering hypertriglyceridemia of any severity, even in elderly individuals. However associations of serum triglycerides (TGs) with adverse health and mortality risk decrease with age, it remains uncl ... Full text Link to item Cite

Dietary Diversity Was Positively Associated with Psychological Resilience among Elders: A Population-Based Study.

Journal Article Nutrients · March 18, 2019 The association between dietary diversity (DD) and psychological resilience among older people is an underdeveloped area of research. This cross-sectional study explored the associations of DD with psychological resilience among 8571 community-based elderl ... Full text Link to item Cite

Cognitive decline and mortality among community-dwelling Chinese older people.

Journal Article BMC Med · March 15, 2019 BACKGROUND: Whether cognitive decline is related to a higher risk of death independent of the initial cognitive function is inconclusive. Evidence of the association between cognitive decline and mortality among Chinese older people is limited. We aimed to ... Full text Link to item Cite

Age of Retirement and Human Capital in an Aging China, 2015-2050.

Journal Article Eur J Popul · February 15, 2019 As China continues to age rapidly, whether the country should adjust the official retirement age, and if so, when and how, are currently major policy concerns. We examine the impact of postponing the retirement age on the human capital of China in the next ... Full text Link to item Cite

Association Between Late-Life Blood Pressure and the Incidence of Cognitive Impairment: A Community-Based Prospective Cohort Study.

Journal Article J Am Med Dir Assoc · February 2019 OBJECTIVES: To investigate the association between late-life blood pressure and the incidence of cognitive impairment in older adults. DESIGN: Prospective cohort study. SETTING: Community-living older adults from 22 provinces in China. PARTICIPANTS: We inc ... Full text Link to item Cite

Residential greenness and mortality in oldest-old women and men in China: a longitudinal cohort study.

Journal Article Lancet Planet Health · January 2019 BACKGROUND: Exposure to natural vegetation, or greenness, might affect health through several pathways, including increased physical activity and social engagement, improved mental health, and reductions in exposure to air pollution, extreme temperatures, ... Full text Link to item Cite

Combined associations of hs-CRP and cognitive function with all-cause mortality among oldest-old adults in Chinese longevity areas: a prospective cohort study.

Journal Article Immun Ageing · 2019 BACKGROUND: Inflammatory markers, such as high sensitivity C-reactive protein (hs-CRP), and cognitive impairment (CI) are associated with mortality; CRP is related to the deterioration of CI. However, it is still unknown whether these two indices predict m ... Full text Link to item Cite

All-cause mortality risk associated with long-term exposure to ambient PM2·5 in China: a cohort study.

Journal Article Lancet Public Health · October 2018 BACKGROUND: Evidence from cohort studies in North America and Europe indicates that long-term exposure to fine particulate matter (PM2·5) is associated with an increased mortality risk. However, this association has rarely been quantified at higher ambient ... Full text Link to item Cite

Association of Body Mass Index With Disability in Activities of Daily Living Among Chinese Adults 80 Years of Age or Older.

Journal Article JAMA Netw Open · September 7, 2018 IMPORTANCE: Body mass index (BMI) shows a U-shaped association with impaired physical functioning among adults; the association is reduced or eliminated with aging. OBJECTIVE: To examine whether BMI is associated with subsequent disability in activities of ... Full text Link to item Cite

Associations of Body Mass Index and Waist Circumference with 3-Year All-Cause Mortality Among the Oldest Old: Evidence from a Chinese Community-Based Prospective Cohort Study.

Journal Article J Am Med Dir Assoc · August 2018 OBJECTIVE: Current international and national guidelines for body mass index (BMI) and waist circumference (WC) have been recommended to all adults. However, whether recommendations applied to the oldest old (aged 80+) is poorly known. The study objective ... Full text Link to item Cite

Sex Differences in Genetic Associations With Longevity.

Journal Article JAMA Netw Open · August 2018 IMPORTANCE: Sex differences in genetic associations with human longevity remain largely unknown; investigations on this topic are important for individualized health care. OBJECTIVE: To explore sex differences in genetic associations with longevity. DESIGN ... Full text Link to item Cite

Revisiting the association of blood pressure with mortality in oldest old people in China: community based, longitudinal prospective study.

Journal Article BMJ · June 5, 2018 OBJECTIVE: To examine the associations of blood pressure with all cause mortality and cause specific mortality at three years among oldest old people in China. DESIGN: Community based, longitudinal prospective study. SETTING: 2011 and 2014 waves of the Chi ... Full text Link to item Cite

The correlation of copy number variations with longevity in a genome-wide association study of Han Chinese.

Journal Article Aging (Albany NY) · June 5, 2018 Copy number variations (CNVs) have been shown to cause numerous diseases, however, their roles in human lifespan remain elusive. In this study, we investigate the association of CNVs with longevity by comparing the Han Chinese genomes of long-lived individ ... Full text Link to item Cite

Incorporating biomarkers into the study of socio-economic status and health among older adults in China.

Journal Article SSM Popul Health · December 2017 The social gradient in health - that individuals with lower SES have worse health than those with higher SES- is welldocumented using self-reports of health in more developed countries. Less is known about the relationship between SES and health biomarkers ... Full text Open Access Link to item Cite

Identification of new genetic variants of HLA-DQB1 associated with human longevity and lipid homeostasis-a cross-sectional study in a Chinese population.

Journal Article Aging (Albany NY) · November 10, 2017 Healthy longevity has been an unremitting pursuit of human, but its genetic and the environment causes are still unclear. As longevity population is a good healthy aging model for understanding how the body begin aging and the process of aging, and plasma ... Full text Link to item Cite

The oldest-old in China - Authors' reply.

Journal Article Lancet · August 26, 2017 Full text Link to item Cite

Malthus' population theory is still wrong

Journal Article Kexue Tongbao/Chinese Science Bulletin · July 25, 2017 In this article, I try to answer the question-"Will Malthus continue to be wrong?", one of the 125 most challenging scientific questions raised by Science at its 125th anniversary ceremony, through a comprehensive review and analysis of historical backgrou ... Full text Cite

Demographics, phenotypic health characteristics and genetic analysis of centenarians in China.

Journal Article Mech Ageing Dev · July 2017 After a brief introduction to the background, significance and unique features of the centenarian population in China, we describe the Chinese Longitudinal Healthy Longevity Study (CLHLS), which is the world's largest study of centenarians, nonagenarians, ... Full text Open Access Link to item Cite

Leisure activities, education, and cognitive impairment in Chinese older adults: a population-based longitudinal study.

Journal Article Int Psychogeriatr · May 2017 BACKGROUND: We examine the association between leisure-time activities and the risk of developing cognitive impairment among Chinese older people, and further investigate whether the association varies by educational level. METHODS: This follow-up study in ... Full text Link to item Cite

Survival, disabilities in activities of daily living, and physical and cognitive functioning among the oldest-old in China: a cohort study.

Journal Article Lancet · April 22, 2017 BACKGROUND: The oldest-old (those aged ≥80 years) are the most rapidly growing age group globally, and are most in need of health care and assistance. We aimed to assess changes in mortality, disability in activities of daily living, and physical and cogni ... Full text Open Access Link to item Cite

Projecting the Number of Elderly with Cognitive Impairment in China Using a Multi-State Dynamic Population Model

Journal Article System Dynamics Review · April 1, 2017 China is aging rapidly, and the number of Chinese elderly with dementia is expected to rise. This paper projects, up to year 2060, the number of Chinese elderly within four distinct cognitive states. A multi-state population model was developed using syste ... Full text Open Access Cite

A U-shaped Association Between Blood Pressure and Cognitive Impairment in Chinese Elderly.

Journal Article J Am Med Dir Assoc · February 1, 2017 OBJECTIVES: Higher or lower blood pressure may relate to cognitive impairment, whereas the relationship between blood pressure and cognitive impairment among the elderly is not well-studied. The study objective was to determine whether blood pressure is as ... Full text Open Access Link to item Cite

Dietary Diversity and Cognitive Function among Elderly People: A Population-Based Study.

Journal Article J Nutr Health Aging · 2017 OBJECTIVES: To explore associations of dietary diversity with cognitive function among Chinese elderly. DESIGN: This cross-sectional study was conducted in 2011-2012, data were analyzed using multiple linear regression and logistic regression models. SETTI ... Full text Link to item Cite

Older Parents Benefit More in Health Outcome From Daughters' Than Sons' Emotional Care in China.

Journal Article J Aging Health · December 2016 OBJECTIVE: To examine whether older parents in China would benefit more from daughters' care than from sons' emotional care. METHOD: Analysis of the unique data sets of the Chinese Longitudinal Healthy Longevity Survey conducted in 2002, 2005, and 2008-200 ... Full text Open Access Link to item Cite

The effects of China's universal two-child policy.

Journal Article Lancet · October 15, 2016 In October, 2015, China's one-child policy was replaced by a universal two-child policy. The effects of the new policy are inevitably speculative, but predictions can be made based on recent trends. The population increase will be relatively small, peaking ... Full text Link to item Cite

[Association between serum albumin and cognitive performance in elderly Chinese].

Journal Article Zhonghua Liu Xing Bing Xue Za Zhi · October 10, 2016 Objective: To explore association between serum albumin level and cognitive performance in elderly Chinese. Methods: All the subjects aged ≥65 years in the 8 longevity areas in Chinese longitudinal health longevity survey (CLHLS) were invited to participat ... Full text Link to item Cite

Vitamin D Levels and the Risk of Cognitive Decline in Chinese Elderly People: the Chinese Longitudinal Healthy Longevity Survey.

Journal Article J Gerontol A Biol Sci Med Sci · October 2016 BACKGROUND: Vitamin D has a neuroprotective function, potentially important for the prevention of cognitive decline. Prospective studies from Western countries support an association between lower vitamin D level and future cognitive decline in elderly peo ... Full text Open Access Link to item Cite

Interaction Between the FOXO1A-209 Genotype and Tea Drinking Is Significantly Associated with Reduced Mortality at Advanced Ages.

Journal Article Rejuvenation Res · June 2016 On the basis of the genotypic/phenotypic data from Chinese Longitudinal Healthy Longevity Survey (CLHLS) and Cox proportional hazard model, the present study demonstrates that interactions between carrying FOXO1A-209 genotypes and tea drinking are signific ... Full text Open Access Link to item Cite

Tourism Experiences and Self-Rated Health Among Older Adults in China.

Journal Article J Aging Health · June 2016 OBJECTIVE: To investigate factors associated with tourism experiences, and the association between tourism experiences and subsequent self-rated health. METHOD: Multilevel logistic regression models and four waves of panel data from a large nationally repr ... Full text Link to item Cite

Serum cholesterol levels within the high normal range are associated with better cognitive performance among Chinese elderly

Journal Article Journal of Nutrition, Health and Aging · March 1, 2016 Objectives: The association between cognitive function and cholesterol levels is poorly understood and inconsistent results exist among the elderly. The purpose of this study is to investigate the association of cholesterol level with cognitive performance ... Full text Open Access Cite

Novel loci and pathways significantly associated with longevity.

Journal Article Sci Rep · February 25, 2016 Only two genome-wide significant loci associated with longevity have been identified so far, probably because of insufficient sample sizes of centenarians, whose genomes may harbor genetic variants associated with health and longevity. Here we report a gen ... Full text Open Access Link to item Cite

Coresidence with elderly parents and female labor supply in China

Journal Article Demographic Research · January 1, 2016 Background The female labor force participation rate in China has experienced a significant decline over the past two decades. Existing studies attribute this decline to the retreat of government protection of female employment and growing gender discrimin ... Full text Cite

Prevalence and Risk Factors of Atrial Fibrillation in Chinese Elderly: Results from the Chinese Longitudinal Healthy Longevity Survey.

Journal Article Chin Med J (Engl) · September 20, 2015 BACKGROUND: Prevalence of atrial fibrillation (AF) is increasing as the world ages. AF is associated with higher risk of mortality and disease, including stroke, hypertension, heart failure, and dementia. Prevalence of AF differs with each population studi ... Full text Open Access Link to item Cite

[Association between anemia and 3-year all-cause mortality among oldest old people in longevity areas in China].

Journal Article Zhonghua Liu Xing Bing Xue Za Zhi · July 2015 OBJECTIVE: To explore the association between anemia and 3-year all-cause mortality among the oldest old people in longevity areas in China. METHODS: In August 2012, questionnaire survey, health examination and blood test were conducted among 929 old peopl ... Link to item Cite

The impact of health insurance on health outcomes and spending of the elderly: evidence from China's New Cooperative Medical Scheme.

Journal Article Health Econ · June 2015 This paper investigates the effects of China's New Cooperative Medical Scheme (NCMS) on health outcomes and healthcare expenditure of the elderly in rural China, using panel data from the 2005 and 2008 waves of the Chinese Longitudinal Healthy Longevity Su ... Full text Link to item Cite

Prevalence and correlates of successful ageing: a comparative study between China and South Korea.

Journal Article Eur J Ageing · June 2015 Successful ageing is often defined as a later life with less disease and disease-related disability, high level of cognitive and physical functions, and an active life style. Few studies have compared successful ageing across different societies in a non-W ... Full text Link to item Cite

GxE interactions between FOXO genotypes and drinking tea are significantly associated with prevention of cognitive decline in advanced age in China.

Journal Article J Gerontol A Biol Sci Med Sci · April 2015 Logistic regression analysis based on data from 822 Han Chinese oldest old aged 92+ demonstrated that interactions between carrying FOXO1A-266 or FOXO3-310 or FOXO3-292 and tea drinking at around age 60 or at present time were significantly associated with ... Full text Open Access Link to item Cite

Implications of changes in households and living arrangements for future home-based care needs and costs for disabled elders in China.

Journal Article J Aging Health · April 2015 OBJECTIVES: To better understand future home-based care needs and costs for disabled elders in China. METHOD: To further develop and apply the ProFamy extended cohort-component method and the most recent census and survey data. RESULTS: (a) Chinese disable ... Full text Link to item Cite

Low-density lipoprotein cholesterol was inversely associated with 3-year all-cause mortality among Chinese oldest old: data from the Chinese Longitudinal Healthy Longevity Survey.

Journal Article Atherosclerosis · March 2015 OBJECTIVE: Low-density lipoprotein cholesterol (LDL-C) is a risk factor for survival in middle-aged individuals, but conflicting evidence exists on the relationship between LDL-C and all-cause mortality among the elderly. The goal of this study was to asse ... Full text Open Access Link to item Cite

Implementing the universal two-child policy as soon as possible is a win-win policy for both the nation and people

Other China Center for Economic Research (CCER) · 2015 Working Paper No. C2015002 ... Cite

Vitamin D levels and cognition in elderly adults in China.

Journal Article J Am Geriatr Soc · November 2014 OBJECTIVES: To evaluate the association between vitamin D level and cognitive impairment in individuals aged 60 and older. DESIGN: Cross-sectional cohort study. SETTING: Chinese Longitudinal Healthy Longevity Survey, a community-based cohort study in areas ... Full text Open Access Link to item Cite

Direct and indirect effects of childhood conditions on survival and health among male and female elderly in China.

Journal Article Soc Sci Med · October 2014 This paper investigates whether childhood conditions affect survival and health, both directly and indirectly through the mediating variable of adulthood socioeconomic status, among Chinese elderly. Using data from the 2008-2009 and 2011-2012 waves of the ... Full text Link to item Cite

Gender-dependent association of body mass index and waist circumference with disability in the Chinese oldest old.

Journal Article Obesity (Silver Spring) · August 2014 OBJECTIVES: To explore associations of BMI and waist circumference (WC) with disability among the Chinese oldest old. METHODS: The 5,495 oldest old in the sixth wave of Chinese Longitudinal Healthy Longevity Study conducted in 2011 were included in this st ... Full text Open Access Link to item Cite

PhenX RISING: real world implementation and sharing of PhenX measures.

Journal Article BMC Med Genomics · March 20, 2014 BACKGROUND: The purpose of this manuscript is to describe the PhenX RISING network and the site experiences in the implementation of PhenX measures into ongoing population-based genomic studies. METHODS: Eighty PhenX measures were implemented across the se ... Full text Open Access Link to item Cite

Trends in functional and activity limitations among Chinese oldest-old, 1998 to 2008

Journal Article Population and Development Review · January 1, 2014 China has the world's largest oldest-old population, but information on trends in late-life disability is lacking. We use data from the Chinese Longitudinal Healthy Longevity Survey for 1998 to 2008 to determine whether prevalence of limitations with physi ... Full text Cite

Tea consumption and mortality in the oldest-old Chinese.

Journal Article J Am Geriatr Soc · November 2013 OBJECTIVES: To investigate the association between tea consumption and mortality in the oldest-old Chinese. DESIGN: Population-based longitudinal data from the Chinese Longitudinal Healthy Longevity Survey (CLHLS) were analyzed using a Cox semiparametric p ... Full text Link to item Cite

Interactions between social/ behavioral factors and ADRB2 genotypes may be associated with health at advanced ages in China.

Journal Article BMC Geriatr · September 9, 2013 BACKGROUND: Existing literature indicates that ADRB2 gene is associated with health and longevity, but none of previous studies investigated associations of carrying the ADRB2 minor alleles and interactions between ADRB2 genotypes and social/behavioral fac ... Full text Open Access Link to item Cite

Household and living arrangement projections at the subnational level: an extended cohort-component approach.

Journal Article Demography · June 2013 This article presents the core methodological ideas and empirical assessments of an extended cohort-component approach (known as the "ProFamy model"), and applications to simultaneously project household composition, living arrangements, and population siz ... Full text Link to item Cite

Health consequences of familial longevity influence among the Chinese elderly.

Journal Article J Gerontol A Biol Sci Med Sci · April 2013 BACKGROUND: A comparative analysis between centenarians' children and neighborhood controls is an efficient approach to learn how familial longevity influence and its interaction with environmental factors affect healthy aging. Yet, there are few extant st ... Full text Link to item Cite

Common genetic variants of the β2-adrenergic receptor affect its translational efficiency and are associated with human longevity.

Journal Article Aging Cell · December 2012 β-adrenoceptors are the common pharmacological targets for the treatment of cardiovascular diseases and asthma. Genetic modifications of β-adrenergic system in engineered mice affect their lifespan. Here, we tested whether genes encoding for key components ... Full text Link to item Cite

Healthiness of survival and quality of death among oldest old in China using fuzzy sets.

Journal Article J Aging Health · October 2012 OBJECTIVE: To investigate healthiness of survival and quality of death among oldest-old Chinese. METHODS: Grade of Membership (GoM) method is applied to fulfill our goals using a nationwide longitudinal survey in China. RESULTS: GoM method generates six pu ... Full text Link to item Cite

High normal plasma triglycerides are associated with preserved cognitive function in Chinese oldest-old.

Journal Article Age Ageing · September 2012 OBJECTIVE: to explore the relationship between blood lipids/lipoproteins and cognitive function in the Chinese oldest-old. DESIGN: multivariate statistical analysis using cross-sectional data. SETTING: community-based setting in longevity areas in China. S ... Full text Link to item Cite

A new classification of function and disability in China: subtypes based on performance-based and self-reported measures.

Journal Article J Aging Health · August 2012 OBJECTIVES: To develop a new classification method to describe incidence and prevalence of function and disability and their predictors in Chinese older adults. METHODS: Data were obtained from 16,020 older adults in the 2002 wave of Chinese Longitudinal H ... Full text Link to item Cite

High sensitivity C-reactive protein associated with different health predictors in middle-aged and oldest old Chinese.

Journal Article Biomed Environ Sci · June 2012 OBJECTIVE: To describe the distribution of plasma high sensitivity C-reactive protein (hsCRP) and explore the relationship between hsCRP and metabolic risk factors among residents living in longevity areas of China. METHODS: 268 individuals aged between 40 ... Full text Link to item Cite

A Multistate Life Table Analysis of Union Regimes in the United States: Trends and Racial Differentials, 1970-2002.

Journal Article Popul Res Policy Rev · April 1, 2012 We estimate trends and racial differentials in marriage, cohabitation, union formation and dissolution (union regimes) for the period 1970-2002 in the United States. These estimates are based on an innovative application of multistate life table analysis t ... Full text Link to item Cite

Birth measurements, family history, and environmental factors associated with later-life hypertensive status.

Journal Article Am J Hypertens · April 2012 BACKGROUND: This birth cohort study was conducted to investigate the contribution of prenatal and antenatal environmental exposures to later-life hypertensive status. METHODS: Two thousand five hundred and three individuals born in 1921-1954 at the Peking ... Full text Link to item Cite

Population Aging, Disability and Housing Accessibility: Implications for Sub-national Areas in the United States

Journal Article Housing Studies · March 1, 2012 The older population in many countries is large and growing rapidly, increasing the number of people with disabilities and driving up the need for accessible housing. In a previous study, the authors projected the number of households in the USA with at le ... Full text Cite

Tea drinking and cognitive function in oldest-old Chinese.

Journal Article J Nutr Health Aging · 2012 OBJECTIVE: We examined the longitudinal association between tea drinking frequency and cognitive function in a large sample of oldest-old Chinese. DESIGN: population-based longitudinal cohort study. SETTING: The Chinese Longitudinal Healthy Longevity Surve ... Full text Link to item Cite

Towards Deeper Research and Better Policy for Healthy Aging --Using the Unique Data of Chinese Longitudinal Healthy Longevity Survey.

Journal Article China Economic J · 2012 The objectives of this review article are to facilitate deeper research and better policy analysis for healthy aging, which not only means surviving to old ages in good health, but also mean the economics and society of our country would be aging healthily ... Full text Link to item Cite

The association between resilience and survival among Chinese elderly

Journal Article · December 1, 2011 Resilience, a psychological construct, has been defined differently in extant-theoretical writings. Luthar et al. © 2011 Springer Science+Business Media, LLC. ... Full text Cite

Association of mtDNA haplogroup F with healthy longevity in the female Chuang population, China.

Journal Article Exp Gerontol · December 2011 Human longevity is a complex heritable genetic trait. Based on substantial evidence from model organisms, it is clear that mitochondria play a pivotal role in aging and lifespan. However, the effects that mitochondrial genome variations have upon longevity ... Full text Link to item Cite

Interactions between life stress factors and carrying the APOE4 allele adversely impact self-reported health in old adults.

Journal Article J Gerontol A Biol Sci Med Sci · October 2011 Based on the multiple logistic regression analysis of data from a random sample of 1,023 old adults collected in Taiwan in 2000, we found that interactions between carrying the APOE4 allele and one of four life stress factors (relocated mainlander, living ... Full text Open Access Link to item Cite

Health inputs and cumulative health deficits among the older Chinese.

Journal Article Soc Sci Med · March 2011 Using a health economics framework, we examined how both individual level investments at different life stages and current community-level environmental factors affect individual health stock and flows at old ages. We used a nationwide dataset from the 200 ... Full text Link to item Cite

Effects of demographic and retirement-age policies on future pension deficits, with an application to China.

Journal Article Popul Dev Rev · 2011 A simple method is proposed for projecting future deficits in a defined benefit or defined contribution pension scheme. The annual pension deficit rate is expressed in terms of the elderly dependency ratio (determined by demographic factors), the average r ... Full text Link to item Cite

Household vehicle consumption forecasts in the United States, 2000 to 2005

Journal Article International Journal of Market Research · January 1, 2011 Full text Cite

Association of Religious Participation With Mortality Among Chinese Old Adults.

Journal Article Res Aging · January 2011 This research examines the association of religious participation with mortality using a longitudinal data set collected from 9,017 oldest-old aged 85+ and 6,956 younger elders aged 65 to 84 in China in 2002 and 2005 and hazard models. Results show that ad ... Full text Link to item Cite

Effects of FOXO genotypes on longevity: a biodemographic analysis.

Journal Article J Gerontol A Biol Sci Med Sci · December 2010 Based on data from 760 centenarians and 1060 middle-age controls (all Han Chinese), this article contributes biodemographic insights and syntheses concerning the magnitude of effects of the FOXO genotypes on longevity. We also estimate independent and join ... Full text Open Access Link to item Cite

Association of Birth Weight with Health and Long-Term Survival up to Middle and Old Ages in China.

Journal Article J Popul Ageing · December 2010 This study is based on an unique dataset of birth records of 11,693 persons born in Beijing, China from 1921-54 and from clinical examinations (May 2003-April 2005) of 2,085 tracked surviving cohort members (aged 50-82) to diagnose seven major chronic dise ... Full text Link to item Cite

Relationship between birth size and coronary heart disease in China.

Journal Article Ann Med · December 2010 BACKGROUND: Clinical epidemiological studies suggested a link between fetal growth conditions and later coronary heart disease (CHD) in adult life. However, no such studies have been conducted in a Chinese population. OBJECTIVES: We investigated the associ ... Full text Link to item Cite

Effect of new disability subtype on 3-year mortality in Chinese older adults.

Journal Article J Am Geriatr Soc · October 2010 OBJECTIVES: To examine a new method of classifying disability subtypes by combining self-reported and performance-based tools to predict mortality in older Chinese adults. DESIGN: Prospective cohort study. SETTING: Community-dwelling older adults. PARTICIP ... Full text Link to item Cite

Low birth weight is associated with components of the metabolic syndrome.

Journal Article Metabolism · September 2010 The purpose of the study was to investigate the association between birth weight and number of metabolic syndrome (MetS) components in an urban Chinese cohort. Individuals (N = 2019) who were born between 1921 and 1954 at the Peking Union Medical College H ... Full text Link to item Cite

The association between resilience and survival among Chinese elderly.

Journal Article Demographic research · July 2010 Based on the unique longitudinal data of the elderly aged 65+ with a sufficiently large sub-sample of the oldest-old aged 85+ from the Chinese Longitudinal Healthy Longevity Survey, we construct a resilience scale with 7 indicators for the Chinese elderly, ... Full text Cite

Familial transmission of human longevity among the oldest-old in china

Journal Article Journal of Applied Gerontology · June 1, 2010 This paper investigates the relationship between longevity of parents and exceptional longevity (survival to age 80 or older) of offspring, using data from the first three waves of the Chinese Longitudinal Healthy Longevity Survey. We apply the Fixed-Attri ... Full text Cite

Sociodemographic and health correlates of sleep quality and duration among very old Chinese.

Journal Article Sleep · May 2010 STUDY OBJECTIVES: To examine factors associated with self-reported sleep quality and duration among very old adults in China. DESIGN: Cross-sectional analysis of the 2005 wave of the Chinese Longitudinal Healthy Longevity Survey (CLHLS). SETTING: In-home i ... Full text Link to item Cite

Challenges of population aging in China

Journal Article China Economic Journal · March 1, 2010 Utilizing the most recent census and survey data as well as the new ProFamy method, this paper presents and analyzes the trends of challenges of population aging and elderly living arrangements in China in the first half of twenty-first century. It discuss ... Full text Cite

Associations of environmental factors with elderly health and mortality in China.

Journal Article Am J Public Health · February 2010 OBJECTIVES: We examined the effects of community socioeconomic conditions, air pollution, and the physical environment on elderly health and survival in China. METHODS: We analyzed data from a nationally representative sample of 15 973 elderly residents of ... Full text Link to item Cite

Resilience significantly contributes to exceptional longevity.

Journal Article Curr Gerontol Geriatr Res · 2010 Objective. We aim to investigate whether centenarians are significantly more resilient than younger elders and whether resilience significantly contributes to exceptional longevity. Data. We use a unique dataset from the Chinese Longitudinal Healthy Longev ... Full text Link to item Cite

Genetic association of FOXO1A and FOXO3A with longevity trait in Han Chinese populations.

Journal Article Hum Mol Genet · December 15, 2009 FOXO1A and FOXO3A are two members of the FoxO family. FOXO3A has recently been linked to human longevity in Japanese, German and Italian populations. Here we tested the genetic contribution of FOXO1A and FOXO3A to the longevity phenotype in Han Chinese pop ... Full text Link to item Cite

The association between the risk of adult cerebral vascular disease and the intrauterine growth: A retrospective birth cohort study in a Chinese population

Journal Article Chinese Journal of Neurology · September 1, 2009 Objective: To investigate the possible relationship between the risk of cerebral vascular disease (CVD) in adulthood and the intrauterine growth in a Chinese cohort. Methods: Two thousand five hundred and three infants born in the Peking Union Medical Coll ... Full text Cite

Changing health status and health expectancies among older adults in China: gender differences from 1992 to 2002.

Journal Article Soc Sci Med · June 2009 Numerous studies document improvements in health status and health expectancies among older adults over time. However, most evidence is from developed nations and gender differences in health trends are often inconsistent. It remains unknown whether change ... Full text Link to item Cite

Frailty and type of death among older adults in China: prospective cohort study.

Journal Article BMJ · April 9, 2009 OBJECTIVE: To examine the association between frailty and type of death among the world's largest oldest-old population in China. DESIGN: Prospective cohort study. SETTING: 2002 and 2005 waves of the Chinese longitudinal healthy longevity survey carried ou ... Full text Link to item Cite

Frailty and mortality among Chinese at advanced ages.

Journal Article J Gerontol B Psychol Sci Soc Sci · March 2009 OBJECTIVES: This study investigates the factors associated with frailty and the association of frailty with mortality in a national sample of adults aged 65-109 in China. METHODS: Using the 2002 wave of the Chinese Longitudinal Healthy Longevity Survey, we ... Full text Link to item Cite

Access to healthcare services makes a difference in healthy longevity among older Chinese adults.

Journal Article Soc Sci Med · January 2009 The positive impact of access to healthcare on health and survival among older adults is well-documented in Western societies. However, whether the pattern still holds in developing countries where healthcare coverage is more limited is largely unknown. Ch ... Full text Link to item Cite

Apolipoprotein E polymorphism, life stress and self-reported health among older adults.

Journal Article J Epidemiol Community Health · April 2008 OBJECTIVE: To examine the association of self-reported health (SRH) with the apolipoprotein E (APOE) gene, life stress, and sociobehavioural factors in adults aged 55 and over. DESIGN: Secondary analysis of data from the Social Environment and Biomarkers o ... Full text Link to item Cite

Evidence of a relationship between infant birth weight and later diabetes and impaired glucose regulation in a Chinese population.

Journal Article Diabetes Care · March 2008 OBJECTIVE: The aim of this study was to determine the influence of birth weight, a marker of fetal growth, on the development of later impaired glucose metabolism throughout the life span of people living in China. RESEARCH DESIGN AND METHODS: We recorded ... Full text Link to item Cite

The association of childhood socioeconomic conditions with healthy longevity at the oldest-old ages in China.

Journal Article Demography · August 2007 Based on unique data from the largest-ever sample of the Chinese oldest-old aged 80 and older, our multivariate logistic regression analyses show that either receiving adequate medical service during sickness in childhood or never/rarely suffering from ser ... Full text Link to item Cite

Options for fertility policy transition in China

Journal Article Population and Development Review · June 1, 2007 This article compares five currently debated scenarios for fertility policy transition in China, in terms of their implications for future population growth and population aging, the proportions of elderly living alone, labor force trends, pension deficits ... Full text Cite

Factors Associated with Place of Death Among Chinese Oldest-Old

Journal Article Journal of Applied Gerontology · 2007 Cite

U.S. Family Household Momentum and Dynamics: An Extension and Application of the ProFamy Method

Journal Article Population Research and Policy Review · March 2006 Cite

Computing time-varying sex-age-specific rates of marriage/union formation and dissolution in family household projection or simulation

Journal Article Demographic Research · December 3, 2004 This article presents two procedures that are useful in both macro and micro projection/simulation models concerning marriage/union formation and dissolution. One is for computing time-varying sex-age-specific rates that are consistent with independently p ... Full text Cite

Sociodemographic effects on the onset and recovery of ADL disability among Chinese oldest-old

Journal Article Demographic Research · August 4, 2004 By pooling the data from the three waves (1998, 2000, and 2002) of the Chinese Longitudinal Health and Longevity Survey, this study examines the association of sociodemographic factors with the onset and recovery of ADL disability including changes in func ... Full text Cite

A new method for correcting under-estimation of disabled life expectancy and an application to the Chinese oldest-old.

Journal Article Demography · May 2004 This article demonstrates that disabled life expectancies that are based on conventional multistate life-table methods are significantly underestimated because of the assumption of no changes in functional status between age x and death. We present a new m ... Full text Link to item Cite

China's revolutions and intergenerational relations

Journal Article POPULATION AND DEVELOPMENT REVIEW · March 1, 2004 Link to item Cite

Association of late childbearing with healthy longevity among the oldest-old in China.

Journal Article Popul Stud (Camb) · 2004 Statistical analysis of a large and unique longitudinal data-set demonstrates that childbearing after age 35 or 40 is associated with survival and healthy survival among very old Chinese women and men. The association is stronger for women than for men. Th ... Full text Link to item Cite

Oldest-old mortality in China

Journal Article Demographic Research · April 18, 2003 We find that the Kannisto model, a two-parameter logistic formula, fits Han Chinese death rates at oldest-old ages better than the Gompertz and four other models. Chinese death rates appear to be roughly similar to Swedish and Japanese rates after age 97 f ... Full text Cite

Gender differentials of the oldest old in China

Journal Article Research on Aging · January 1, 2003 Based on unique data from a sample of nearly 9,000 people ages 80 to 105 interviewed in 22 provinces in 1998, we found that gender differentials in educational attainment among the Chinese oldest old are enormous: Many more women are illiterate. Oldest old ... Full text Cite

Association of divorce with socio-demographic covariates in China, 1955-1985: Event history analysis based on data collected in Shanghai, Hebei, and Shaanxi

Journal Article Demographic Research · August 29, 2002 Based on a unique data set on the event history of marriage and divorce collected in the In-Depth Fertility Surveys conducted in Shanghai, Shaanxi, and Hebei in 1985 and a multivariate hazards model, this paper investigates the association between divorce ... Cite

Adjusting period tempo changes with an extension of Ryder's basic translation equation.

Journal Article Demography · May 2002 We show that the observed changes in the period tempo of fertility are biased and derive a new formula for adjusting such bias. We present illustrative applications of our proposed method to the cases of the United States and Taiwan. We then describe the r ... Full text Link to item Cite

Sociodemographic and Health Profiles of Oldest Old in China.

Journal Article Population and Development Review · 2002 Cite

Functional capacity and self-evaluation of health and life of oldest old in China

Journal Article Journal of Social Issues · January 1, 2002 This study is based on survey data from a sample of 8,805 elders aged 80-105 in 22 provinces of China. Rural oldest old are significantly more active in daily living than urban oldest old; adaptation is perhaps the major explanation of this difference. Fem ... Full text Cite

Sociodemographic and health profiles of the oldest old in China

Journal Article Population and Development Review · 2002 Unique data from a 1998 healthy longevity baseline survey provide demographic, socio-economic, and health characteristics of the oldest old, aged 80-105, in China. This subpopulation is growing rapidly and is likely to need extensive social and health serv ... Cite

Sociodemographic and health profiles of the oldest old in China

Journal Article Population and Development Review · January 1, 2002 Unique data from a 1998 healthy longevity baseline survey provide demographic, socio-economic, and health characteristics of the oldest old, aged 80-105, in China. This subpopulation is growing rapidly and is likely to need extensive social and health serv ... Full text Cite

A sensitivity analysis of the Bongaarts-Feeney method for adjusting bias in observed period total fertility rates.

Journal Article Demography · February 2001 Our sensitivity analysis shows that the adjusted TFR'(t) using the formula of Bongaarts and Feeney (1998), which assumes an invariant shape for the fertility schedule, usually does not differ significantly from an adjusted TFR"(t) that allows the shape of ... Full text Link to item Cite

The healthy longevity survey and the active life expectancy of the oldest old in China

Journal Article Population · January 1, 2001 This paper presents a summarized description of the background, objectives, study design, and data quality assessment of the 1998 Chinese Healthy Longevity Survey. The initial findings on the specific topic of active vs. disabled life expectancies are also ... Cite

A Demographic Analysis of Family Households in China, 1982-1995.

Journal Article Journal of Comparative Family Studies · 2001 Cite

Family Dynamics of 63 Million (in 1990) to More Than 330 Million (in 2050) Elders in China

Journal Article Demographic Research · May 2000 Based on censuses micro data files, population and family households projections, this paper analyses extremely rapid population aging, family dynamics and living arrangements of the elderly in China. Both our and the U.N.’s most recent projections confirm ... Cite

Regional analysis of divorce in China since 1980.

Journal Article Demography · May 2000 This paper estimates and discusses divorce measures in China and its 30 provinces since 1980. The propensity for divorce in China increased 42% between 1982 and 1990. Substantial increases in divorce were observed in all provinces except Xinjiang and Shanx ... Link to item Cite

A simple method for projecting or estimating and β: An extension of the brass relational Gompertz Fertility Model

Journal Article Population Research and Policy Review · January 1, 2000 This paper proposes a simple method that analytically links the parameters α and β, which are not demographically interpretable and measurable in the Brass Relational Gompertz Fertility Model, with demographic measures of median age and interquartile range ... Full text Cite

The impact of institutional reform from 1979 through 1987 on fertility in rural China

Journal Article China Economic Review · January 1, 1999 This empirical study brings together data on the local timing of the rural household responsibility system (HRS) reforms in China from 1979 through 1987 and assesses the association of the local reforms with individual parity-specific fertility changes as ... Full text Cite

Biodemographic trajectories of longevity.

Journal Article Science · May 8, 1998 Old-age survival has increased substantially since 1950. Death rates decelerate with age for insects, worms, and yeast, as well as humans. This evidence of extended postreproductive survival is puzzling. Three biodemographic insights--concerning the correl ... Full text Link to item Cite

Conditions in China influencing outmigration

Conference SILENT DEBATE: ASIAN IMMIGRATION AND RACISM IN CANADA · January 1, 1998 Link to item Cite

Household projection using conventional demographic data

Journal Article POPULATION AND DEVELOPMENT REVIEW · January 1, 1998 Link to item Cite

Migration in the urban-rural hierarchy of China: insights from the microdata of the 1987 National Survey.

Journal Article Environ Plan A · April 1997 Microdata from the 1987 National Population Survey are used to analyze internal migration in China in the 1980s. The focus is on the impact of migration policies on rural-urban migration. "There are two main findings. First, although the migration policy r ... Full text Link to item Cite

A multi-dimensional model for projecting family households--with an illustrative numerical application.

Journal Article Math Popul Stud · 1997 "This paper develops a multi-dimensional model for projecting households and population. The model is constructed to ensure consistency between the demographic events occurring to males and females as well as to parents and children. The model permits proj ... Full text Link to item Cite

Changes in the divorce rate and age distribution in China since the 1980s.

Journal Article Soc Sci China · 1997 "The divorce rate in China during the 1980s was much higher than before for a number of reasons. In order to understand this phenomenon, the authors will make a comparison between the divorce rates, and the age and duration of the marriage at the time of d ... Link to item Cite

Spousal-residence separation among Chinese young couples.

Journal Article Environ Plan A · May 1996 The factors affecting the residential separation of spouses in China are examined. "Based on the microdata of the 1987 National Population Survey, we find that the variation in spousal-residence separations among Chinese young couples in the mid-1980s is w ... Full text Link to item Cite

Is fertility in china in 1991–92 far below replacement level?

Journal Article Population Studies · March 1, 1996 In this article it is shown that the extremely low fertility rates reported in China – well below replacement level – derived from the Chinese Survey in 1992 are false. Serious under-reporting of most recent births in China was caused by various factors, a ... Full text Cite

Fertility of rural China: effects of local family planning and health programs.

Journal Article J Popul Econ · November 1995 "The rationing of births in China after the 1979 announcement of the 'one child family policy' has been held responsible for the rapid decrease in Chinese fertility, whereas other observers have noted that parallel fertility declines occurred with voluntar ... Full text Link to item Cite

Aging in China: Progress and Policy Responses.

Journal Article Reviews in Clinical Gerontology · 1995 Cite

Aging in China: Progress and Policy Responses

Journal Article Reviews in Clinical Gerontology · January 1, 1995 Full text Cite

Leaving the parental home: Census-based estimates for China, Japan, South Korea, United States, France, and Sweden

Journal Article Population Studies · March 1, 1994 Using the iterative intra-cohort interpolation procedure, this article tries to remedy the lack of data on home-leaving by providing an international comparison of estimated census-based single-year age-specific net rates of leaving home for males and fema ... Full text Cite

China's agenda for an old-age insurance program in rural areas.

Journal Article J Aging Soc Policy · 1994 Based on a field study conducted in August 1993 by the author, this article discusses the experimental program of old-age insurance in rural areas of China. The achievements made so far, the feasibility of old-age insurance in rural areas, and the problems ... Full text Link to item Cite

Marriage and fertility in China: 1950-1989.

Journal Article Genus · 1993 "This article presents a graphical and a life table analysis that summarizes some 14,000 values of data by single year of age and time on marriage and fertility in China up to 1989. In the 1970s, age at first marriage shifted upward by about four years, an ... Link to item Cite

Causes and implications of the recent increase in the reported sex ratio at birth in China

Journal Article Population & Development Review · January 1, 1993 This article shows that the reported sex ratio at birth increased substantially in China during the 1980s. An application of the reverse survival method to data from the 1990 census, the 1987 One Percent Population Survey, and the 1988 Two-per-Thousand Fer ... Cite

Some problems of future demographic processes in China.

Journal Article Soc Sci China · January 1992 "In this paper, which is based on a projection model of rural-urban population dynamics established by the authors, we make use of the investigative data of the one percent national population sample of 1987 and analog calculations on almost 200 demographi ... Link to item Cite

Population tradeoffs in China

Journal Article Policy Sciences · November 1, 1991 China's population of 1.1 billion is growing. China's population is also aging: the elderly may number 300 to 400 million by 2050. Efforts to reduce the population growth will increase the proportion elderly. To increase the size of the work force, a subst ... Full text Cite

An Demographic Decomposition of Recent Increase in Crude Birth Rates in China.

Journal Article Population and Development Review · 1991 Cite

A demographic decomposition of the recent increase in crude birth rates in China

Journal Article Population & Development Review · 1991 A decomposition of recent increases in the crude birth rate into components attributable to changes in age structure, marriage pattern, and marital fertility demonstrates that changing age structure and the declining age at marriage are mainly responsible ... Cite

The impact of urbanization and delayed childbearing on population growth and aging in China

Journal Article Population & Development Review · January 1, 1989 Urbanization and delayed childbearing in China are likely to reduce future national birth rates and significantly slow population growth for two reasons. First, urban residents are apt to continue to have substantially lower fertility rates than rural resi ... Cite

Is China's Family Planning Program Tightening Up?

Journal Article Population and Development Review · 1989 Cite

Changing demographic characteristics and the family status of chinese women

Journal Article Population Studies · July 1, 1988 The model developed in this paper extends Bongaarts’s nuclear family model into a general one that accounts for both nuclear and three-generation families, and which is expected to be more widely applicable. In the paper a simulation and comparison of two ... Full text Cite

Changes in family structure in China: a simulation study.

Journal Article Population & Development Review · January 1, 1987 It is widely recognized that remarkable changes in Chinese family structure have accompanied changes in the rate of marriage, fertility, and mortality in recent decades. Life expectancy of China's population increased from 47 years in 1950 to 67.9 years in ... Cite

Marriage and fertility in China: a graphical analysis.

Journal Article Population & Development Review · January 1, 1985 Data from China's 1982 one-in-a-thousand fertility survey are used to construct contour maps of Chinese marriage and fertility. They offer a panoramic view of the interaction of age, period, and cohort variations. The maps display long-term trends over the ... Cite