Zheng Chang | Scholars@Duke

Zheng Chang
Associate Professor of Radiation Oncology

Dr. Chang's research interests include radiation therapy treatment assessment using MR quantitative imaging, image guided radiation therapy (IGRT), fast MR imaging using parallel imaging and strategic phase encoding, and motion management for IGRT.

Current Appointments & Affiliations

Associate Professor of Radiation Oncology, Radiation Oncology, Clinical Science Departments 2014

Contact Information

Box 3295 Med Ctr, Durham, NC 27710
DUMC Box 3295, Radiation Oncology, Durham, NC 27710
zheng.chang@duke.edu (919) 681-2608

Background
Education, Training, & Certifications
- Ph.D., University of British Columbia 2006
Duke Appointment History
- Assistant Professor of Radiation Oncology, Radiation Oncology, Clinical Science Departments 2013 - 2014
- Assistant Professor of Radiation Oncology, Radiation Oncology, Clinical Science Departments 2007 - 2013
Research
Selected Grants
- Motion Management Using 4D-MRI for Liver Cancer in Radiation Therapy awarded by National Institutes of Health 2013 - 2016
- Cross-disciplinary Training in Medical Physics awarded by National Institutes of Health 2007 - 2013
Publications & Artistic Works
Selected Publications
- Conference Papers
  - Stanhope, C, Chang, Z, Wang, Z, Yin, F-F, Kim, G, Salama, JK, Kirkpatrick, J, and Adamson, J. "Physics considerations for single-isocenter, volumetric modulated arc radiosurgery for treatment of multiple intracranial targets." May 2016. Full Text
  - Adamson, J, Chang, Z, Cai, J, Palta, M, Horton, J, Yin, F, and Blitzblau, R. "Induction of Gradual Changes in Blood Oxygen Levels in Post Lumpectomy Breast Tissue With Breath Holding: Results of a Pilot Study." November 2015. Full Text
  - Wang, C, Horton, J, Yin, F, and Chang, Z. "Treatment Assessment Using Dynamic Fractal Signature Dissimilarity as a Novel Biomarker for Early-Stage Breast Cancer Radiation Therapy: A Feasibility Study." November 2015. Full Text
  - Chang, Z, Libby, B, and Lamb, J. "US Guided Systems for Brachytherapy." June 2015. Full Text Link to Item
  - Wang, C, Subashi, E, Yin, F, and Chang, Z. "Therapeutic Response Assessment Using a Novel Gray Level Local Power Matrix (GLLPM) in DCE-MRI Texture Analysis: Feasibility Study." June 2015. Full Text Link to Item
  - Dong, Y, Chang, Z, and Ji, J. "Imaging and localizing interventional devices by susceptibility mapping using MRI." January 2014. Full Text
  - Horton, JK, Blitzblau, RC, Yoo, S, Georgiade, GS, Geradts, J, Baker, JA, Chang, Z, Duffy, E, and Hwang, ES. "Preoperative Single:Fraction Partial Breast Radiation Therapy: A Novel Phase 1 Dose-Escalation Protocol and Exploration of Breast Cancer Radiation Response." October 1, 2013. Full Text Link to Item
  - Liu, Y, Chang, Z, Czito, B, Bashir, M, Yin, F, and Cai, J. "4D-MRI Using Sagittal Acquisition and Body Area as Respiratory Surrogate." October 1, 2013. Full Text Link to Item
  - Chang, Z, Yan, H, and Yin, F. "SU-E-J-150: Investigation of Feasibility of Concurrent Orthogonal KV and MV X-Ray Imaging for Tagrget Tracking During Dose Delivery for Stereotactic Body Radiotherapy (SBRT): A Pilot Phantom Study." June 2013. Full Text
  - Chang, Z, Yin, F, Yoo, S, and Horton, J. "SU-E-CAMPUS-J-04: Evaluating Radiation-Induced Changes with Diffusion Weighted MRI and Dynamic Contrast Enhanced MRI in Patients with Early Stage Breast Cancer Treated with Stereotactic Body Radiotherapy: Initial Results." June 2013. Full Text
  - Cuneo, KC, Vredenburgh, J, Desjardins, A, Peters, K, Sampson, J, Allen, K, Chang, Z, Duffy, E, Peterson, B, and Kirkpatrick, JP. "Impact of Concurrent and Adjuvant Bevacizumab on the Risk of Radiation Necrosis Following Radiosurgery for Recurrent Glioma." November 1, 2012. Full Text Link to Item
  - Cuneo, KC, Vredenburgh, J, Desjardins, A, Peters, K, Sampson, J, Chang, Z, and Kirkpatrick, J. "EFFECTS OF CONCURRENT AND ADJUVANT BEVACIZUMAB ON THE RISK OF RADIATION NECROSIS FOLLOWING RADIOSURGERY FOR RECURRENT GLIOMA." October 2012. Link to Item
  - Chang, Z, Kirkpatrick, J, Cai, J, Wang, Z, and Yin, F. "WE-A-217A-09: Evaluating Radiation-Induced White Matter Changes in Patients with Recurrent Malignant Gliomas under Treatment of Stereotactic Radiosurgery Using Diffusion Tensor Imaging." June 2012. Full Text
  - Chang, Z, Kirkpatrick, J, Cai, J, Wang, Z, and Yin, F. "Evaluating Radiation-Induced White Matter Changes in Patients with Recurrent Malignant Gliomas Under Treatment of Stereotactic Radiosurgery Using Diffusion Tensor Imaging." June 2012. Full Text Link to Item
  - Chang, Z, Wu, Q, Adamson, J, Ren, L, Bowsher, J, Yan, H, Thomas, A, and Yin, F. "SU-E-T-74: Assessing Effects of Ion Collection Efficiency in Flattening Filter-Free (FFF) Beams on Three TrueBeam Machines." June 2012. Full Text
  - Chang, Z, Wu, Q, Adamson, J, Ren, L, Bowsher, J, Yan, H, Thomas, A, and Yin, F. "Assessing Effects of Ion Collection Efficiency in Flattening Filter-Free (FFF) Beams On Three TrueBeam Machines." June 2012. Full Text Link to Item
  - Chang, Z, Wu, Q, Adamson, J, Ren, L, Bowsher, J, Yan, H, Thomas, A, and Yin, F. "Commissioning and Dosimetric Characteristics of TrueBeam System: Composite Data of Three TrueBeam Machines." June 2012. Full Text Link to Item
  - Chang, Z. "Introduction to Treatment Assessment of Radiation Therapy Using MR Functional Imaging and Its Application to Intracranial Stereotactic Radiosurgery." June 2012. Full Text Link to Item
  - Qin, Y, Chang, Z, Segars, W, Yin, F, and Cai, J. "4D-MRI Based On Body Area (BA) Surrogate and Sagittal Image Acquisition." June 2012. Full Text Link to Item
  - Tseng, T, Chang, Z, Yin, F, and Wang, Z. "Evaluation of the Dosimetric Accuracy of Stereotactic Radiosurgery with Cone-Beam Computed Tomography Localization." June 2012. Full Text Link to Item
  - Cai, J, Chang, Z, OˈDaniel, J, Yoo, S, Jian, Y, Ge, H, and Yin, F. "TU-E-BRC-08: Investigation of Anatomical Surrogate for 4DCT Imaging." June 2011. Full Text
  - Chang, Z, Liu, T, Cai, J, Chen, Q, Wang, Z, and Yin, F. "SU-E-T-123: Evaluation of Integrated Gating Systems on a Novalis Tx System Using Quantitative Motion Tracking Analyses and Efficient Time-Delay Measurements." June 2011. Full Text
  - Chang, Z, Xiang, Q, and Yin, F. "MO-F-211-04: Fast Phase Contrast MR Angiography with Simplified Skipped Phase Encoding and Edge Deghosting with Array Coil Enhancement (S- SPEED-ACE)." June 2011. Full Text
  - Adamson, J, Chang, Z, Wang, Z, Yin, F, and Cai, J. "SU-GG-I-140: Maximum Intensity Projection (MIP) Imaging Using Multi-Slice Cine MRI." June 2010. Full Text
  - Cai, J, Chang, Z, and Yin, F. "TU-B-201B-02: Self-Sorted Four-Dimensional CT Using Body Volume as Respiratory Surrogate." June 2010. Full Text
  - Cai, J, Chang, Z, and Yin, F. "SU-GG-I-148: Self-Sorted Four-Dimensional Magnetic Resonance Imaging: A Feasibility Study." June 2010. Full Text
  - Chang, Z, Cai, J, Wang, Z, and Yin, F. "SU-GG-J-67: Evaluating Dynamic Magnetic Resonance Imaging Using a New Design of Phantom: Validation with Fast Megavoltage Fluoroscopic Imaging." June 2010. Full Text
  - Chang, Z, Xiang, Q, Shen, H, and Yin, F. "SU-GG-I-144: Accelerating Non-Contrast-Enhanced MRA with Inflow Inversion Recovery by Using Skipped Phase Encoding and Edge Deghosting (SPEED)." June 2010. Full Text
  - Jian, Y, Godfrey, D, Chang, Z, and Yin, F. "SU-GG-I-24: Improving IGRT Efficiency Using GPU-Based Ultrafast Reconstruction of DTS/CBCT and DRR." June 2010. Full Text
  - Senick, S, and Chang, Z. "SU-GG-J-157: Evaluation of Volumetric Losses during Radiation Therapy Using Image Guidance of Electronic Portal Imaging Device." June 2010. Full Text
  - Wang, Z, Chang, Z, Chen, Q, and Yin, F. "SU-GG-J-62: Use Winston-Lutz Test to Check Cone Beam CT Isocenter Accuracy for Imaging Guided Intracranial Stereotactic Radiosurgery." June 2010. Full Text
  - Wang, Z, Kirkpatrick, J, Chang, Z, Cai, J, Zhuang, T, and Yin, F. "SU-GG-T-530: Comparison of Coplanar and Non-Coplanar Intensity Modulated Arc Techniques for Treatment of Intracranial Multi-Focal Stereotactic Radiosurgery." June 2010. Full Text
  - Cai, J, Chang, Z, Wang, Z, and Yin, F. "Extracting Breathing Signal from Image Fourier Transform for Developing 4D-MRI." 2010. Full Text Link to Item
  - Chang, Z, Wang, Z, Ma, J, Wu, Q, Kirkpatrick, J, and Yin, F. "Cone-Beam CT 6 Degree-of-Freedom Image-Guidance for Intracranial Frameless Stereotactic RadioSurgery using 6D Robotic Couch." 2010. Full Text Link to Item
  - Ghafoori, A, Allen, K, Nelson, J, Clough, R, Yin, F, Wang, Z, Chang, Z, Kelsey, C, and Kirkpatrick, J. "Stereotactic Body Radiotherapy (SBRT) in Patients Previously Treated with External Beam Radiation Therapy." 2010. Full Text Link to Item
  - Chang, Z, Wang, Z, Wu, Q, Bowsher, J, Yoo, S, and Yin, F. "SU-FF-T-309: Quality Assurance for Imaging Guided Stereotactic RadioSurgery with Novalis Tx™ System." June 2009. Full Text
  - Chang, Z, Wang, Z, Wu, Q, Kirkpatrick, J, and Yin, F. "SU-EE-A3-02: Imaging Guided Frameless Stereotactic RadioSurgery Using CBCT 6D Image Registration and 6D Couch On Novalis Tx™ System." June 2009. Full Text
  - O'Daniel, J, McMahon, R, Chang, Z, Yan, H, Sakhalkar, H, Das, S, Wu, Q, and Yin, F. "SU-FF-T-314: Patient-Specific Quality Assurance Techniques for RapidArc Radiotherapy." June 2009. Full Text
  - Wang, Z, Kirkpatrick, J, Chang, Z, O'Daniel, J, Willett, C, and Yin, F. "SU-FF-T-545: Feasibility Study for Treatment of Intracranial Multi-Focal Stereotactic Radiosurgery with Multiple Intensity Modulated Arc Technique." June 2009. Full Text
  - Wang, Z, Kirkpatrick, J, Wu, Q, Chang, Z, Willett, C, and Yin, F. "SU-FF-T-548: Comparison of Cone-Beam CT and Frame-Based Localizations for Stereotactic Radiosurgery with Fixed Head Rings and Removable Frames." June 2009. Full Text
  - Wu, Q, McMahon, R, Chang, Z, Zhuang, T, O'Daniel, J, Yoo, S, Zhu, X, and Yin, F. "SU-FF-T-301: Clinical Implementation and Commission of Volumetric Modulated Arc Therapy." June 2009. Full Text
  - Chang, Z, Wang, Z, Ma, J, O'Daniel, J, Kirkpatrick, J, and Yin, F. "Six-dimensional Image Guidance for Spinal Noninvasive SRS/SBRT: Comparison between ExacTrac X-ray 6D with kV Cone-beam CT." 2009. Full Text Link to Item
  - Wang, Z, Kirkpatrick, JP, Wu, QJ, Chang, Z, Willett, CG, and Yin, F. "Imaging Guided Stereotactic Radiosurgery and its Accuracy Compared to Frame-based Localization." 2009. Full Text Link to Item
  - Chang, Z, Craciunescu, O, and Yin, F. "SU-EE-A4-04: Accelerating Breast Dynamic Contrast Enhanced MRI with Efficient Multiple Acquisitions by SPEED Using Shared Information." June 2008. Full Text
  - Chang, Z, Yoo, S, Wang, Z, and Yin, F. "SU-GG-J-177: The Application of An ASi-Based EPID to Guide Intensity Modulated Radiation Therapy (IMRT) of Head-And-Neck Cancer." June 2008. Full Text
  - Wang, Z, Chang, Z, Wu, Q, Zhou, S, Huntzinger, C, and Yin, F. "SU-GG-T-446: Dosimetric Characteristics of High Definition Multi-Leaf Collimator." June 2008. Full Text
  - Wang, Z, Wu, Q, Chang, Z, Kirkpatrick, J, and Yin, F. "SU-GG-T-454: Localization Accuracy of Cone-Beam CT Guided Radiosurgery as Investigated Utilizing a Geometric Phantom." June 2008. Full Text
  - Chang, Z, Wang, Z, Lee, W, and Yin, F. "MRI-based postimplant dosimetric assessment." 2008. Full Text Link to Item
  - Wang, Z, Kirkpatrick, JP, Wu, QJ, Chang, Z, Willett, CG, and Yin, F. "Can cone beam CT replace frame-based localization for stereotactic radiosurgery?." 2008. Full Text Link to Item
  - Wu, QJ, Wang, Z, Kirkpatrick, JP, Chang, Z, Zhou, S, Willett, CG, and Yin, F. "Dosimetrical evaluation of SRS/SBRT techniques." 2008. Full Text Link to Item
- Journal Articles
  - Wang, C, Yin, F-F, Kirkpatrick, JP, and Chang, Z. "Accelerated Brain DCE-MRI Using Iterative Reconstruction With Total Generalized Variation Penalty for Quantitative Pharmacokinetic Analysis: A Feasibility Study." Technology in cancer research & treatment 16, no. 4 (August 2017): 446-460. Full Text
  - Wang, C, Yin, F-F, Segars, WP, Chang, Z, and Ren, L. "Development of a Computerized 4-D MRI Phantom for Liver Motion Study." Technology in cancer research & treatment (January 2017): 1533034617723753-. Full Text
  - Harris, W, Yin, FF, Wang, C, Chang, Z, Cai, J, Zhang, Y, and Ren, L. "Ultrafast Volumetric Cine Magnetic Resonance Imaging (UVC-MRI) for Real-Time 3-Dimensional Target Localization/Tracking." International journal of radiation oncology, biology, physics 96, no. 2S (October 2016): E626-. Full Text
  - Wang, C, Horton, JK, Yin, F-F, and Chang, Z. "Assessment of Treatment Response With Diffusion-Weighted MRI and Dynamic Contrast-Enhanced MRI in Patients With Early-Stage Breast Cancer Treated With Single-Dose Preoperative Radiotherapy: Initial Results." Technology in cancer research & treatment 15, no. 5 (October 2016): 651-660. Full Text
  - Wang, C, Horton, JK, Yin, FF, Subashi, E, and Chang, Z. "Early-Stage Breast Radiation Therapy Assessment Using Transcytolemmal Water Exchange Analysis of DCE-Magnetic Resonance Imaging: Initial Results." International journal of radiation oncology, biology, physics 96, no. 2S (October 2016): E617-. Full Text
  - Wang, C, Subashi, E, Liang, X, Yin, F-F, and Chang, Z. "Evaluation of the effect of transcytolemmal water exchange analysis for therapeutic response assessment using DCE-MRI: a comparison study." Physics in medicine and biology 61, no. 13 (July 2016): 4763-4780. Full Text
  - Chino, JP, Belley, MD, Chang, Z, Langloss, B, Yoshizumi, TT, Therien, MJ, and Craciunescu, OI. "Real Time Dosimetry for Gynecologic Brachytherapy: Initial Results of a Prospective Clinical Trial (vol 93, pg S203, 2015)." INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS 95, no. 2 (June 1, 2016): 858-859. Link to Item
  - Harris, W, Ren, L, Cai, J, Zhang, Y, Chang, Z, and Yin, F-F. "A Technique for Generating Volumetric Cine-Magnetic Resonance Imaging." International journal of radiation oncology, biology, physics 95, no. 2 (June 2016): 844-853. Full Text
  - Wang, C, Subashi, E, Yin, F-F, and Chang, Z. "Dynamic fractal signature dissimilarity analysis for therapeutic response assessment using dynamic contrast-enhanced MRI." Medical physics 43, no. 3 (March 2016): 1335-1347. Full Text
  - Wang, C, Yin, F-F, and Chang, Z. "An efficient calculation method for pharmacokinetic parameters in brain permeability study using dynamic contrast-enhanced MRI." Magnetic resonance in medicine 75, no. 2 (February 2016): 739-749. Full Text
  - Blitzblau, RC, Arya, R, Yoo, S, Baker, JA, Chang, Z, Palta, M, Duffy, E, and Horton, JK. "A phase 1 trial of preoperative partial breast radiation therapy: Patient selection, target delineation, and dose delivery." Practical radiation oncology 5, no. 5 (September 2015): e513-e520. Full Text
  - Dong, Y, Chang, Z, Xie, G, Whitehead, G, and Ji, JX. "Susceptibility-based positive contrast MRI of brachytherapy seeds." Magnetic resonance in medicine 74, no. 3 (September 2015): 716-726. Full Text
  - Horton, JK, Blitzblau, RC, Yoo, S, Geradts, J, Chang, Z, Baker, JA, Georgiade, GS, Chen, W, Siamakpour-Reihani, S, Wang, C, Broadwater, G, Groth, J, Palta, M, Dewhirst, M, Barry, WT, Duffy, EA, Chi, J-TA, and Hwang, ES. "Preoperative Single-Fraction Partial Breast Radiation Therapy: A Novel Phase 1, Dose-Escalation Protocol With Radiation Response Biomarkers." International journal of radiation oncology, biology, physics 92, no. 4 (July 2015): 846-855. Full Text
  - Adamson, J, Chang, Z, Cai, J, Palta, M, Horton, J, Yin, F, and Blitzblau, R. "SU-E-J-223: A BOLD Contrast Imaging Sequence to Evaluate Oxygenation Changes Due to Breath Holding for Breast Radiotherapy: A Pilot Study." Medical physics 42, no. 6 (June 2015): 3317-. Full Text
  - Chang, Z. "MO-FG-210-01: Commissioning An US System for Brachytherapy: An Overview of Physics, Instrumentation, and Techniques." Medical physics 42, no. 6 (June 2015): 3572-. Full Text
  - Stanhope, C, Chang, Z, Wang, Z, Yin, F, Kim, G, Salama, J, Kirkpatrick, J, and Adamson, J. "SU-E-T-613: Physics Considerations for Single-Isocenter Volumetric Modulated Arc Radiosurgery for Treatment of Multiple Intracranial Targets." Medical physics 42, no. 6 (June 2015): 3477-. Full Text
  - Wang, C, Subashi, E, Yin, F, and Chang, Z. "TH-CD-204-07: Evaluation of Dynamic Fractal Signature Dissimilarity as a Novel Biomarker in Therapeutic Response Assessment Using Dynamic Contrast-Enhanced MRI." Medical physics 42, no. 6 (June 2015): 3733-. Full Text
  - Wang, C, Subashi, E, Yin, F, and Chang, Z. "SU-D-BRA-01: Therapeutic Response Assessment Using a Novel Gray Level Local Power Matrix (GLLPM) in DCE-MRI Texture Analysis: Feasibility Study." Medical physics 42, no. 6 (June 2015): 3212-. Full Text
  - Xie, Y, Wang, C, Horton, J, and Chang, Z. "TU-F-CAMPUS-J-02: Evaluation of Textural Feature Extraction for Radiotherapy Response Assessment of Early Stage Breast Cancer Patients Using Diffusion Weighted MRI and Dynamic Contrast Enhanced MRI." Medical physics 42, no. 6 (June 2015): 3641-. Full Text
  - Kirkpatrick, JP, Wang, Z, Sampson, JH, McSherry, F, Herndon, JE, Allen, KJ, Duffy, E, Hoang, JK, Chang, Z, Yoo, DS, Kelsey, CR, and Yin, F-F. "Defining the optimal planning target volume in image-guided stereotactic radiosurgery of brain metastases: results of a randomized trial." International journal of radiation oncology, biology, physics 91, no. 1 (January 2015): 100-108. Full Text
  - Yang, J, Cai, J, Wang, H, Chang, Z, Czito, BG, Bashir, MR, Palta, M, and Yin, F-F. "Is diaphragm motion a good surrogate for liver tumor motion?." International journal of radiation oncology, biology, physics 90, no. 4 (November 2014): 952-958. Full Text
  - Liu, Y, Yin, F-F, Chang, Z, Czito, BG, Palta, M, Bashir, MR, Qin, Y, and Cai, J. "Investigation of sagittal image acquisition for 4D-MRI with body area as respiratory surrogate." Medical physics 41, no. 10 (October 2014): 101902-. Full Text
  - Yang, J, Cai, J, Wang, H, Chang, Z, Czito, BG, Bashir, MR, and Yin, FF. "Four-dimensional magnetic resonance imaging using axial body area as respiratory surrogate: Initial patient results." International Journal of Radiation Oncology Biology Physics 88, no. 4 (March 15, 2014): 907-912. Full Text
  - Yang, J, Cai, J, Wang, H, Chang, Z, Czito, BG, Bashir, MR, and Yin, F-F. "Four-dimensional magnetic resonance imaging using axial body area as respiratory surrogate: initial patient results." International journal of radiation oncology, biology, physics 88, no. 4 (March 2014): 907-912. Full Text
  - Chang, Z, Kirkpatrick, JP, Wang, Z, Cai, J, Adamson, J, and Yin, F-F. "Evaluating radiation-induced white matter changes in patients treated with stereotactic radiosurgery using diffusion tensor imaging: a pilot study." Technol Cancer Res Treat 13, no. 1 (February 2014): 21-28. Full Text Link to Item
  - Qiu, J-J, Chang, Z, Horton, JK, Wu, Q-RJ, Yoo, S, and Yin, F-F. "Dosimetric comparison of 3D conformal, IMRT, and V-MAT techniques for accelerated partial-breast irradiation (APBI)." Medical dosimetry : official journal of the American Association of Medical Dosimetrists 39, no. 2 (January 27, 2014): 152-158. Full Text
  - Qiu, JJ, Chang, Z, Horton, JK, Wu, QRJ, Yoo, S, and Yin, FF. "Dosimetric comparison of 3D conformal, IMRT, and V-MAT techniques for accelerated partial-breast irradiation (APBI)." Medical Dosimetry 39, no. 2 (January 1, 2014): 152-158. Full Text
  - Liu, Y, Chang, Z, Yuan, H, Fales, AM, and Vo-Dinh, T. "Quintuple-modality (SERS-MRI-CT-TPL-PTT) plasmonic nanoprobe for theranostics." Nanoscale 5, no. 24 (December 21, 2013): 12126-12131. Full Text Link to Item
  - Dong, Y, Chang, Z, Whitehead, G, and Ji, J. "Localization of brachytherapy seeds in MRI by deconvolution." Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS (October 31, 2013): 2960-2963. Full Text
  - Cabrera, AR, Cuneo, KC, Desjardins, A, Sampson, JH, McSherry, F, Herndon, JE, Peters, KB, Allen, K, Hoang, JK, Chang, Z, Craciunescu, O, Vredenburgh, JJ, Friedman, HS, and Kirkpatrick, JP. "Concurrent stereotactic radiosurgery and bevacizumab in recurrent malignant gliomas: a prospective trial." Int J Radiat Oncol Biol Phys 86, no. 5 (August 1, 2013): 873-879. Full Text Link to Item
  - Chang, Z, Wu, Q, Yan, H, Yang, Y, Giles, W, Busselberg, C, Lipscomb, R, and Yin, F. "SU-E-T-143: Dosimetric Characteristics of TrueBeam STx System with High Definition Multi-Leaf Collimator: Commissioning of Stereotactic Radiosurgery." Medical physics 40, no. 6Part12 (June 2013): 236-237. Full Text
  - Liu, Y, Chang, Z, Czito, B, Bashir, M, Yin, F, and Cai, J. "TH-C-141-07: T2-Weighted 4D-MRI with Combined Phase and Amplitude Sorting." Medical physics 40, no. 6Part32 (June 2013): 540-. Full Text
  - Wu, Q, Chang, Z, Adamson, J, Ren, L, and Yin, F. "SU-E-T-560: A Method to Determine Optimal Dynamic MLC Parameters for Varian Truebeam with Millennium MLC and HDMLC." Medical physics 40, no. 6Part19 (June 2013): 334-. Full Text
  - Yang, J, Cai, J, Wang, H, Chang, Z, Czito, B, Bashir, M, and Yin, F. "WE-C-116-07: Tumor Enhancement Using Deformable Image Registration for Four-Dimensional Magnetic Resonance Imaging (4D-MRI): A Feasibility Study." Medical physics 40, no. 6Part29 (June 2013): 485-. Full Text
  - Yang, J, Yin, F, Wang, H, Chang, Z, Czito, B, Bashir, M, and Cai, J. "TU-G-134-01: 4D-MRI Using Body Area as Internal Respiratory Surrogate: Initial Patient Results." Medical physics 40, no. 6Part28 (June 2013): 460-. Full Text
  - Cai, J, Chang, Z, Czito, B, and Yin, F. "Improving Tumor-to-Tissue CNR of 4D-MRI Using Deformable Image Registration." Practical radiation oncology 3, no. 2 Suppl 1 (April 2013): S8-S9. Full Text
  - Cai, J, Chang, Z, O'Daniel, J, Yoo, S, Ge, H, Kelsey, C, and Yin, F-F. "Investigation of sliced body volume (SBV) as respiratory surrogate. (Published online)" J Appl Clin Med Phys 14, no. 1 (January 7, 2013): 3987-. Link to Item
  - Cabrera, AR, Cuneo, KC, Desjardins, A, Sampson, JH, McSherry, F, II, JEH, Peters, KB, Allen, K, Hoang, JK, Chang, Z, Craciunescu, O, Vredenburgh, JJ, Friedman, HS, and Kirkpatrick, JP. "Concurrent stereotactic radiosurgery and bevacizumab in recurrent malignant gliomas: A prospective trial." International Journal of Radiation Oncology Biology Physics 86, no. 5 (2013): 873-879. Full Text
  - Cai, J, Chang, Z, O'Daniel, J, Yoo, S, Ge, H, Kelsey, C, and Yin, F-F. "Investigation of sliced body volume (SBV) as respiratory surrogate." JOURNAL OF APPLIED CLINICAL MEDICAL PHYSICS 14, no. 1 (2013): 71-80. Full Text Link to Item
  - Chang, Z, Wu, Q, Adamson, J, Ren, L, Bowsher, J, Yan, H, Thomas, A, and Yin, F-F. "Commissioning and dosimetric characteristics of TrueBeam system: composite data of three TrueBeam machines." Med Phys 39, no. 11 (November 2012): 6981-7018. Full Text Link to Item
  - Chang, Z, Wu, Q, Adamson, J, Ren, L, Bowsher, J, Yan, H, Thomas, A, and Yin, F. "SU-E-T-104: Commissioning and Dosimetric Characteristics of TrueBeam System: Composite Data of Three TrueBeam Machines." Medical physics 39, no. 6Part11 (June 2012): 3726-. Full Text
  - Chang, Z. "WE-E-BRA-01: Introduction to Treatment Assessment of Radiation Therapy Using MR Functional Imaging and Its Application to Intracranial Stereotactic Radiosurgery." Medical physics 39, no. 6Part27 (June 2012): 3958-. Full Text
  - Cuneo, KC, Zagar, TM, Brizel, DM, Yoo, DS, Hoang, JK, Chang, Z, Wang, Z, Yin, FF, Das, SK, Green, S, Ready, N, Bhatti, MT, Kaylie, DM, Becker, A, Sampson, JH, and Kirkpatrick, JP. "Stereotactic radiotherapy for malignancies involving the trigeminal and facial nerves." Technol Cancer Res Treat 11, no. 3 (June 2012): 221-228. Full Text Link to Item
  - Qin, Y, Chang, Z, Segars, W, Yin, F, and Cai, J. "SU-D-218-02: 4D-MRI Based on Body Area (BA) Surrogate and Sagittal Image Acquisition." Medical physics 39, no. 6Part3 (June 2012): 3622-. Full Text
  - Tseng, T, Chang, Z, Yin, F, and Wang, Z. "SU-E-J-32: Evaluation of the Dosimetric Accuracy of Stereotactic Radiosurgery with Cone-Beam Computed Tomography Localization." Medical physics 39, no. 6Part6 (June 2012): 3659-. Full Text
  - Chang, Z, Xiang, Q-S, Shen, H, Ji, J, and Yin, F-F. "Accelerating phase contrast MR angiography by simplified skipped phase encoding and edge deghosting with array coil enhancement." Med Phys 39, no. 3 (March 2012): 1247-1252. Full Text Link to Item
  - Chang, Z, Bowsher, J, Cai, J, Yoo, S, Wang, Z, Adamson, J, Ren, L, and Yin, F-F. "Imaging system QA of a medical accelerator, Novalis Tx, for IGRT per TG 142: Our 1 year experience." Journal of Applied Clinical Medical Physics 13, no. 4 (2012): 113-140.
  - Chang, Z, Bowsher, J, Cai, J, Yoo, S, Wang, Z, Adamson, J, Ren, L, and Yin, FF. "Imaging system QA of a medical accelerator, Novalis Tx, for IGRT per TG 142: our 1 year experience." Journal of applied clinical medical physics / American College of Medical Physics 13, no. 4 (2012): 3754-. (Academic Article)
  - Cai, J, Chang, Z, Wang, Z, Paul Segars, W, and Yin, F-F. "Four-dimensional magnetic resonance imaging (4D-MRI) using image-based respiratory surrogate: a feasibility study." Med Phys 38, no. 12 (December 2011): 6384-6394. Full Text Link to Item
  - Cuneo, KC, Cabrera, AR, Sampson, JH, Allen, KJ, Vredenburgh, JJ, Peters, K, Chang, Z, Herndon, JE, Desjardins, A, Reardon, DA, and Kirkpatrick, J. "Safety results from a prospective study of concurrent radiosurgery and bevacizumab for recurrent malignant glioma." Journal of Clinical Oncology 29, no. 15_suppl (May 20, 2011): 2082-2082. Full Text
  - Chang, Z, Liu, T, Cai, J, Chen, Q, Wang, Z, and Yin, F-F. "Evaluation of integrated respiratory gating systems on a Novalis Tx system. (Published online)" J Appl Clin Med Phys 12, no. 3 (April 4, 2011): 3495-. Link to Item
  - Cabrera, AR, Craciunescu, O, Cuneo, KC, Chang, Z, and Kirkpatrick, JP. "Evaluating Recurrent Gliomas with Diffusion-weighted MR Imaging Before and After Concurrent Radiosurgery and Bevacizumab." INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS 81, no. 2 (2011): S793-S793. Full Text Link to Item
  - Cai, J, Chang, Z, and Yin, F. "Imaging Tumor Motion using 4D-MRI." INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS 81, no. 2 (2011): S122-S123. Full Text Link to Item
  - Chang, Z, Liu, T, Cai, J, Chen, Q, Wang, Z, and Yin, F-F. "Evaluation of integrated respiratory gating systems on a Novalis Tx system." Journal of Applied Clinical Medical Physics 12, no. 3 (2011): 71-79.
  - Cuneo, KC, Cabrera, AR, Sampson, J, Allen, K, Duffy, E, Vredenburgh, JJ, Peters, KB, Chang, Z, Desjardins, A, and Kirkpatrick, JP. "Bevacizumab and Radiosurgery for Recurrent Malignant Glioma: Toxicity Results from a Prospective Pilot Study." INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS 81, no. 2 (2011): S185-S185. Full Text Link to Item
  - Palta, M, Riedel, RF, Vredenburgh, JJ, Cummings, TJ, Green, S, Chang, Z, and Kirkpatrick, JP. "Primary meningeal rhabdomyosarcoma." Sarcoma 2011 (2011): 312802-. Full Text Link to Item
  - Wang, Z, Yin, F, Chang, Z, Sampson, J, and Kirkpatrick, JP. "Imaging-Guided Localization for Stereotactic Radiosurgery of Multiple Intracranial Lesions with a Single Isocenter Setup." INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS 81, no. 2 (2011): S860-S860. Full Text Link to Item
  - Adamson, J, Chang, Z, Wang, Z, Yin, F-F, and Cai, J. "Maximum intensity projection (MIP) imaging using slice-stacking MRI." Med Phys 37, no. 11 (November 2010): 5914-5920. Full Text Link to Item
  - Qiu, J-J, Chang, Z, Wu, QJ, Yoo, S, Horton, J, and Yin, F-F. "Impact of volumetric modulated arc therapy technique on treatment with partial breast irradiation." Int J Radiat Oncol Biol Phys 78, no. 1 (September 1, 2010): 288-296. Full Text Link to Item
  - Chang, Z, Wang, Z, Ma, J, O'Daniel, JC, Kirkpatrick, J, and Yin, F-F. "6D image guidance for spinal non-invasive stereotactic body radiation therapy: Comparison between ExacTrac X-ray 6D with kilo-voltage cone-beam CT." Radiother Oncol 95, no. 1 (April 2010): 116-121. Full Text Link to Item
  - Clift, C, Thomas, A, Adamovics, J, Chang, Z, Das, I, and Oldham, M. "Toward acquiring comprehensive radiosurgery field commissioning data using the PRESAGE/optical-CT 3D dosimetry system." Phys Med Biol 55, no. 5 (March 7, 2010): 1279-1293. Full Text Link to Item
  - Chang, Z, Xiang, Q-S, Shen, H, and Yin, F-F. "Accelerating non-contrast-enhanced MR angiography with inflow inversion recovery imaging by skipped phase encoding and edge deghosting (SPEED)." J Magn Reson Imaging 31, no. 3 (March 2010): 757-765. Full Text Link to Item
  - Ma, J, Chang, Z, Wang, Z, Jackie Wu, Q, Kirkpatrick, JP, and Yin, F-F. "ExacTrac X-ray 6 degree-of-freedom image-guidance for intracranial non-invasive stereotactic radiotherapy: comparison with kilo-voltage cone-beam CT." Radiother Oncol 93, no. 3 (December 2009): 602-608. Full Text Link to Item
  - Wu, QJ, Wang, Z, Kirkpatrick, JP, Chang, Z, Meyer, JJ, Lu, M, Huntzinger, C, and Yin, F-F. "Impact of collimator leaf width and treatment technique on stereotactic radiosurgery and radiotherapy plans for intra- and extracranial lesions. (Published online)" Radiat Oncol 4 (January 21, 2009): 3-. Full Text Link to Item
  - Chang, Z, Xiang, Q-S, Ji, J, and Yin, F-F. "Efficient multiple acquisitions by Skipped Phase Encoding and Edge Deghosting (SPEED) using shared spatial information." Magn Reson Med 61, no. 1 (January 2009): 229-233. Full Text Link to Item
  - Wu, QJ, Wang, Z, Kirkpatrick, JP, Chang, Z, Meyer, JJ, Lu, M, Huntzinger, C, and Yin, F-F. "Impact of collimator leaf width and treatment technique on stereotactic radiosurgery and radiotherapy plans for intra- and extracranial lesions." Radiation oncology (London, England) 4 (2009): 3--. Full Text
  - Chang, Z, Wang, Z, Wu, QJ, Yan, H, Bowsher, J, Zhang, J, and Yin, F-F. "Dosimetric characteristics of novalis Tx system with high definition multileaf collimator." Med Phys 35, no. 10 (October 2008): 4460-4463. Full Text Link to Item
  - Whitehead, G, Chang, Z, and Ji, J. "An automated intensity-weighted brachytherapy seed localization algorithm." Med Phys 35, no. 3 (March 2008): 818-827. Full Text Link to Item
  - Chang, Z, and Xiang, Q-S. "Simplified skipped phase encoding and edge deghosting (SPEED) for imaging sparse objects with applications to MRA." Med Phys 34, no. 8 (August 2007): 3173-3182. Full Text Link to Item
  - Whitehead, G, Zheng, C, and Jim, J. "Automated brachytherapy seed localization using intensity-weighted feature extraction techniques." 2007 4th IEEE International Symposium on Biomedical Imaging: From Nano to Macro - Proceedings (2007): 1152-1155. Full Text
  - Chang, Z, and Xiang, Q-S. "Highly accelerated MRI by skipped phase encoding and edge deghosting with array coil enhancement (SPEED-ACE)." Med Phys 33, no. 10 (October 2006): 3758-3766. Full Text Link to Item
  - Chang, Z, and Xiang, Q-S. "Nonlinear phase correction with an extended statistical algorithm." IEEE Trans Med Imaging 24, no. 6 (June 2005): 791-798. Full Text Link to Item
  - Celler, A, Dixon, KL, Chang, Z, Blinder, S, Powe, J, and Harrop, R. "Problems created in attenuation-corrected SPECT images by artifacts in attenuation maps: a simulation study." J Nucl Med 46, no. 2 (February 2005): 335-343. Link to Item
  - Celler, A, Dixon, KL, Chang, Z, Blinder, S, and Harrop, R. "Problems created in attenuation corrected SPECT images by artifacts in the attenuation maps." IEEE Nuclear Science Symposium Conference Record 4 (2003): 2356-2360.
  - Chang, Z, Liu, H, Huang, N, Wang, Z, and Han, J. "Nanosecond pulse signals restoration via stochastic resonance in the Fabry-Perot cavity with graphene (Published online)." The European Physical Journal Applied Physics . Full Text
Teaching & Mentoring
Recent Courses
- MEDPHY 723: Advanced Brachtherapy/Special Topics and Procedures 2018

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