Early Establishment of Epigenetic Profiles that Increase Cancer Risk in Late Life ·
July 2024
- June 2025
PI ·
Awarded by: ASC-DCI
· $50,000.00
Age Effects on Chemotherapy Targeting Cells Causing Ovarian Cancer Recurrence ·
January 2024
- December 2024
PI ·
Awarded by: Charles Hammond Fund
2023 DCI Spring Pilot Award ·
July 2023
- June 2024
Awarded by: Duke university Cancer institute
Age Effects on Chemotherapy Targeting Cells Causing Ovarian Cancer Recurrence.
The Charles Hammond Research Fund (CHRF) ·
January 2023
- December 2023
Awarded by: Department of Obstetrics and Gynecology, Duke University Medical Center
Single Cell Spatial Transcriptomics in Highly Aggressive and Less Aggressive Ovarian Cancer
The Functions of Complement C7 in the Progression of Ovarian Cancer ·
January 2021
- December 2022
PI ·
Awarded by: Charles B. Hammond Research Fund.
To gain a better understanding of complement component function(s) in the tumor microenvironment and to discover the biomarkers and novel immunotherapeutic
approaches for serous epithelial OC.
The Function of Periostin (POSTN) in the Development of Chemo-Resistance and Recurrence of Ovarian Cancer ·
July 2018
- June 2020
principal investigator (PI) ·
Awarded by: Charles B. Hammond Research Fund
· $10,000.00
We propose to use a 3D cell culture model containing preadipocytes (fibroblasts) and cancer cells to study how POSTN supports cell survival in the presence of chemotherapy reagents. A 3D cell culture model more accurately mimics in vivo tumor formation and how the cells will respond to treatment. We will also test POSTN in cancer formation, chemosensitivity, and tumor recurrence in vivo with a mouse model.
Aim 1. Determine the function of POSTN in OC with a 3D cell culture model.
Aim 2. Determine the function of POSTN in tumor formation and OC recurrence using a xenograft mouse model.
Identification of genes associated with ovarian cancer recurrence using FFPE specimens. ·
2014
Principal Investigator ·
Awarded by: Oncology Research Grant by EA|Quintiles and Illumina
German Research Foundation Scholarship ·
1996
Scholarship Winner ·
Awarded by: Heidelberg University, Germany