Scholars@Duke

• Research
• 

  Selected Grants

  • Use of C. elegans as a model to study aging-associated neurodegeneration awarded by National Institutes of Health 2022 - 2027
  • Use of C. elegans as a model to study aging-associated neurodegeneration awarded by National Institutes of Health 2021 - 2022
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Umano, A., K. Fang, Z. Qu, J. B. Scaglione, S. Altinok, C. J. Treadway, E. T. Wick, et al. “The molecular basis of spinocerebellar ataxia type 48 caused by a de novo mutation in the ubiquitin ligase CHIP.” J Biol Chem 298, no. 5 (May 2022): 101899. https://doi.org/10.1016/j.jbc.2022.101899.
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    • Wang, Yuqing, Shanshan Lu, Yifei Chen, Liang Li, Xia Li, Zhongwei Qu, Junbo Huang, et al. “Smoothened is a therapeutic target for reducing glutamate toxicity in ischemic stroke.” Science Translational Medicine 13, no. 610 (September 2021): eaba3444. https://doi.org/10.1126/scitranslmed.aba3444.
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    • Zhang, Hui, Chunkui Zhang, Zhongwei Qu, Bing Li, Yujuan Su, Xia Li, Yan Gao, and Yizheng Wang. “STN-ANT plasticity is crucial for the motor control in Parkinson's disease model.” Signal Transduction and Targeted Therapy 6, no. 1 (June 2021): 215. https://doi.org/10.1038/s41392-021-00545-z.
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    • Qu, Zhongwei, Albert Zhang, and Dong Yan. “Robo functions as an attractive cue for glial migration through SYG-1/Neph.” Elife 9 (November 19, 2020). https://doi.org/10.7554/eLife.57921.
       Full Text  Open Access Copy  Link to Item
    • Wang, Yuqing, Shanshan Lu, Zhongwei Qu, Lin Wu, and Yizheng Wang. “Sonic hedgehog induces GLT-1 degradation via PKC delta to suppress its transporter activities.” Neuroscience 365 (December 2017): 217–25. https://doi.org/10.1016/j.neuroscience.2017.09.051.
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    • Qu, Zhongwei, Yuqing Wang, Xia Li, Lin Wu, and Yizheng Wang. “TRPC6 expression in neurons is differentially regulated by NR2A- and NR2B-containing NMDA receptors.” Journal of Neurochemistry 143, no. 3 (November 2017): 282–93. https://doi.org/10.1111/jnc.14215.
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    • Miao, Wanying, Zhongwei Qu, Kejie Shi, Dengyue Zhang, Yanyan Zong, Gongliang Zhang, Guangyi Zhang, and Shuqun Hu. “RIP3 S-nitrosylation contributes to cerebral ischemic neuronal injury.” Brain Research 1627 (November 2015): 165–76. https://doi.org/10.1016/j.brainres.2015.08.020.
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    • Qu, Zhong-Wei, Wan-Ying Miao, Shu-Qun Hu, Chong Li, Xing-Li Zhuo, Yan-Yan Zong, Yong-Ping Wu, and Guang-Yi Zhang. “N-methyl-D-aspartate receptor-dependent denitrosylation of neuronal nitric oxide synthase increase the enzyme activity.” Plos One 7, no. 12 (January 2012): e52788. https://doi.org/10.1371/journal.pone.0052788.
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