Ziad F. Gellad | Scholars@Duke

Ziad F. Gellad
Associate Professor of Medicine

Dr. Gellad is an associate professor of medicine in the Division of Gastroenterology at Duke University Medical Center and a faculty member of the Duke Clinical Research Institute. He is also a VA Career Development Awardee and holds an appointment in the Health Services Research and Development Center of Innovation at the Durham VA Medical Center. His research focuses on the implementation of systems engineering methods to improve the quality and value of health care delivery with a specific emphasis in colorectal cancer screening.

Dr. Gellad has also received several innovation grants to develop and implement novel information technology platforms to improve the patient and clinician experience. He is also an active contributor to the innovation and entrepreneurship activities within Duke University and co-founder of a health technology startup in Durham.

Dr. Gellad received his MD and MPH degrees from Johns Hopkins University. He completed a residency in internal medicine and a fellowship in gastroenterology at Duke University Medical Center. He is the Director of Quality for the Division of Gastroenterology and Associate vice Chair for Clinical Innovation in the Department of Medicine at Duke University Medical Center. Dr. Gellad is past-chair of the Quality Measures Committee of the American Gastroenterological Association, associate editor for GI & Hepatology News and is on the Board of Editors for Clinical Gastroenterology and Hepatology.

Current Research Interests

Quality and value of healthcare

Healthcare systems engineering and decision analysis

Outcomes research in Colorectal Cancer Screening

Implementation Science

Current Appointments & Affiliations

Associate Professor of Medicine, Medicine, Gastroenterology, Medicine 2016
Member in the Duke Clinical Research Institute, Duke Clinical Research Institute, Institutes and Centers 2011

Contact Information

2301 Erwin Road, Duke North - DUMC 3703, Durham, NC 27710
2301 Erwin Road, Duke North - DUMC 3703, Durham, NC 27710
ziad.gellad@duke.edu (919) 668-7802
@ZiadGelladMD

Background
Education, Training, & Certifications
- Fellow in Gastroenterology, Medicine, Duke University 2006 - 2009
- Medical Resident, Medicine, Duke University 2003 - 2006
- M.D., Johns Hopkins University 2003
- M.P.H., Johns Hopkins University 2002
Duke Appointment History
- Assistant Professor of Medicine, Medicine, Gastroenterology, Medicine 2009 - 2016
Expertise
Subject Headings
Research
Selected Grants
- Duke Training Grant in Digestive Diseases and Nutrition awarded by National Institutes of Health 1988 - 2021
- EFC 13794 awarded by Sanofi US 2016 - 2019
- DRI13940 Study awarded by Sanofi-Aventis Deutschland GmbH 2016 - 2018
Fellowships, Supported Research, & Other Grants
- HSR&D Career Development Award awarded by Department of Veterans Affairs 2015 - 2020
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Gellad, Z. "Issue Highlights.(Accepted)" Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association 16, no. 10 (October 2018): 1539-1540. Full Text
  - Volk, M, Mellinger, J, Bansal, MB, Gellad, ZF, McClellan, M, and Kanwal, F. "A Roadmap for Value-Based Payment Models among Patients with Cirrhosis." Hepatology (Baltimore, Md.) (September 18, 2018). Full Text
  - Ding, X, Gellad, ZF, Mather, C, Barth, P, Poon, EG, Newman, M, and Goldstein, BA. "Designing risk prediction models for ambulatory no-shows across different specialties and clinics." Journal of the American Medical Informatics Association : Jamia 25, no. 8 (August 2018): 924-930. Full Text
  - Mull, HJ, Gellad, ZF, Gupta, RT, Valle, JA, Makarov, DV, Silverman, T, and Branch-Elliman, W. "Factors Associated With Emergency Department Visits and Hospital Admissions After Invasive Outpatient Procedures in the Veterans Health Administration." Jama Surgery 153, no. 8 (August 2018): 774-776. Full Text
  - Egberg, MD, Gulati, AS, Gellad, ZF, Melmed, GY, and Kappelman, MD. "Improving Quality in the Care of Patients with Inflammatory Bowel Diseases." Inflammatory Bowel Diseases 24, no. 8 (July 2018): 1660-1669. Full Text
  - Crockett, SD, Wani, S, Gardner, TB, Falck-Ytter, Y, Barkun, AN, and American Gastroenterological Association Institute Clinical Guidelines Committee, . "American Gastroenterological Association Institute Guideline on Initial Management of Acute Pancreatitis." Gastroenterology 154, no. 4 (March 2018): 1096-1101. (Review) Full Text
  - Gellad, ZF. "Issue Highlights. (Accepted)" Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 15, no. 10 (October 2017): 1483-1484. Full Text
  - Finn, RT, Boyd, A, Lin, L, and Gellad, ZF. "Bolus Administration of Fentanyl and Midazolam for Colonoscopy Increases Endoscopy Unit Efficiency and Safety Compared With Titrated Sedation." Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association 15, no. 9 (September 2017): 1419-1426.e2. Full Text
  - Japinga, M, Saunders, R, Gellad, ZF, and McClellan, M. "The Evolving Payment Reform Landscape: New Opportunities for Gastroenterology Leadership." Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 15, no. 9 (September 2017): 1322-1325. Full Text
  - Gellad, ZF. "Cultivating Competencies for Value-Based Care." Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 15, no. 7 (July 2017): 969-971. Full Text
  - Day, TE, and Gellad, ZF. "The Value of Negative Results in Quality Improvement: A Simulation Perspective." American journal of medical quality : the official journal of the American College of Medical Quality 31, no. 4 (July 2016): 376-378. Full Text
  - Saini, SD, Adams, MA, Brill, JV, Gupta, N, Naveed, M, Rosenberg, JA, and Gellad, ZF. "Colorectal Cancer Screening Quality Measures: Beyond Colonoscopy." Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association 14, no. 5 (May 2016): 644-647. Full Text
  - Gellad, ZF, and Day, TE. "What Is Value Stream Mapping, and How Can It Help My Practice?." The American journal of gastroenterology 111, no. 4 (April 2016): 447-448. (Review) Full Text
  - Partin, MR, Shaukat, A, Nelson, DB, Gravely, A, Nugent, S, Gellad, ZF, and Burgess, JF. "Reply." Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association 14, no. 3 (March 2016): 486-null. (Letter) Full Text
  - Partin, MR, Gravely, A, Gellad, ZF, Nugent, S, Burgess, JF, Shaukat, A, and Nelson, DB. "Factors Associated With Missed and Cancelled Colonoscopy Appointments at Veterans Health Administration Facilities." Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association 14, no. 2 (February 2016): 259-267. Full Text
  - Seidelman, J, Zuo, R, Udayakumar, K, and Gellad, ZF. "Caught on Capsule: Iron-deficiency Anemia Due to Hookworm Infection." The American journal of medicine 129, no. 2 (February 2016): 167-169. Full Text
  - Rubenstein, JH, Lieberman, D, Fennerty, B, and Gellad, ZF. "Measuring the quality of Barrett's esophagus management with measures that are high quality." Gastroenterology 149, no. 6 (November 2015): 1298-1301. Full Text
  - Rubenstein, JH, Enns, R, Heidelbaugh, J, Barkun, A, and Clinical Guidelines Committee, . "American Gastroenterological Association Institute Guideline on the Diagnosis and Management of Lynch Syndrome." Gastroenterology 149, no. 3 (September 2015): 777-782. (Review) Full Text
  - Mansouraty, G, and Gellad, ZF. "Website Review: Review of patient-oriented websites on hemorrhoids." Gastroenterology (April 25, 2015). Full Text Open Access Copy
  - Gellad, ZF. "Endoscopy unit efficiency." Gastroenterology & hepatology 10, no. 5 (May 2014): 315-317.
  - "Reply." Clinical Gastroenterology and Hepatology 12, no. 3 (March 1, 2014): 527-null. (Letter) Full Text
  - Gellad, ZF, Voils, CI, Lin, L, and Provenzale, D. "Physician perceptions on colonoscopy quality: results of a national survey of gastroenterologists." Gastroenterology research and practice 2014 (January 2014): 510494-. Full Text
  - Taheri, J, Gellad, Z, Burchfield, D, and Cooper, K. "Simulation as a guide for systems redesign in gastrointestinal endoscopy: Appointment template redesign." 2013 Winter Simulations Conference (Wsc) (December 2013). Full Text
  - Gellad, ZF, Thompson, CP, and Taheri, J. "Endoscopy unit efficiency: quality redefined." Clin Gastroenterol Hepatol 11, no. 9 (September 2013): 1046-1049.e1. Full Text Link to Item
  - Gellad, ZF, Voils, CI, Lin, L, and Provenzale, D. "Clinical practice variation in the management of diminutive colorectal polyps: results of a national survey of gastroenterologists." The American Journal of Gastroenterology 108, no. 6 (June 2013): 873-878. Full Text
  - Jackson, GL, Zullig, LL, Zafar, SY, Powell, AA, Ordin, DL, Gellad, ZF, Abbott, D, Schlosser, JM, Hersh, J, and Provenzale, D. "Using NCCN clinical practice guidelines in oncology to measure the quality of colorectal cancer care in the veterans health administration." Journal of the National Comprehensive Cancer Network : Jnccn 11, no. 4 (April 2013): 431-441. Full Text
  - Gellad, Z. "Personalisation of colorectal cancer screening." The Lancet Oncology (2013). Full Text
  - Gellad, Z. "Personalisation of colorectal cancer screening." The Lancet Oncology 14, no. 8 (2013): 673-675. Full Text
  - Taheri, J, Gellad, Z, Burchfield, D, and Cooper, K. "A simulation study to reduce nurse overtime and improve patient flow time at a hospital endoscopy unit." Proceedings Title: Proceedings of the 2012 Winter Simulation Conference (Wsc) (December 2012). Full Text
  - Chan, JL, Lin, L, Feiler, M, Wolf, AI, Cardona, DM, and Gellad, ZF. "Comparative effectiveness of i-SCAN™ and high-definition white light characterizing small colonic polyps." World Journal of Gastroenterology 18, no. 41 (November 2012): 5905-5911. Full Text
  - Gellad, Z, Burchfield, D, Cooper, K, and Taheri, J. "Continuous Nursing Care in GI Endoscopy Improves Nurse and Room Utilization and Decreases Patient Wait Time." AMERICAN JOURNAL OF GASTROENTEROLOGY 107 (October 2012): S778-S779. Link to Item
  - Gellad, ZF, Muir, AJ, McHutchison, JG, Sievert, W, Sharara, AI, Brown, KA, Flisiak, R, Jacobson, IM, Kershenobich, D, Manns, MP, Schulman, KA, and Reed, SD. "Cost-effectiveness of truncated therapy for hepatitis C based on rapid virologic response." Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research 15, no. 6 (September 2012): 876-886. Full Text
  - Gellad, ZF, Reed, SD, and Muir, AJ. "Economic evaluation of direct-acting antiviral therapy in chronic hepatitis C." Antiviral Therapy 17, no. 6 Pt B (January 2012): 1189-1199. (Review) Full Text
  - Gellad, ZF, Stechuchak, KM, Fisher, DA, Olsen, MK, McDuffie, JR, Ostbye, T, and Yancy, WS. "Longitudinal adherence to fecal occult blood testing impacts colorectal cancer screening quality." The American Journal of Gastroenterology 106, no. 6 (June 2011): 1125-1134. Full Text
  - Gellad, ZF, and Provenzale, D. "Reply." Gastroenterology 139, no. 3 (September 2010): 1065-1065. Full Text
  - Gellad, ZF, Weiss, DG, Ahnen, DJ, Lieberman, DA, Jackson, GL, and Provenzale, D. "Colonoscopy withdrawal time and risk of neoplasia at 5 years: results from VA Cooperative Studies Program 380." Am J Gastroenterol 105, no. 8 (August 2010): 1746-1752. Full Text Link to Item
  - Jackson, GL, Melton, LD, Abbott, DH, Zullig, LL, Ordin, DL, Grambow, SC, Hamilton, NS, Zafar, SY, Gellad, ZF, Kelley, MJ, and Provenzale, D. "Quality of nonmetastatic colorectal cancer care in the Department of Veterans Affairs." Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology 28, no. 19 (July 2010): 3176-3181. Full Text
  - Gellad, ZF, and Provenzale, D. "Colorectal cancer: national and international perspective on the burden of disease and public health impact." Gastroenterology 138, no. 6 (June 2010): 2177-2190. (Review) Full Text
  - Gellad, ZF, Almirall, D, Provenzale, D, and Fisher, DA. "Time from positive screening fecal occult blood test to colonoscopy and risk of neoplasia." Dig Dis Sci 54, no. 11 (November 2009): 2497-2502. Full Text Link to Item
  - Gellad, ZF, Hampton, D, Tebbit, CL, Puscas, L, and Pavey, DA. "Bilateral vocal cord paralysis following stent placement for proximal esophageal stricture." Endoscopy 40 Suppl 2 (September 2008): E150-. Full Text Link to Item
  - Gellad, ZF, Almirall, D, Provenzale, D, and Fisher, DA. "Time from positive screening fecal occult blood test to colonoscopy and risk of neoplasia." GASTROENTEROLOGY 134, no. 4 (April 2008): A151-A152. Link to Item
  - Gellad, ZF, Alexander, BD, Liu, JK, Griffith, BC, Meyer, AM, Johnson, JL, and Muir, AJ. "Severity of Clostridium difficile-associated diarrhea in solid organ transplant patients." Transpl Infect Dis 9, no. 4 (December 2007): 276-280. Full Text Link to Item
  - Gellad, ZF, and Lyles, KW. "Direct-to-consumer advertising of pharmaceuticals." The American Journal of Medicine 120, no. 6 (June 2007): 475-480. (Review) Full Text
  - van der Keyl, H, Gellad, ZF, and Owen, JA. "Disparity in the kinetics of onset of hypermutation in immunoglobulin heavy and light chains." Immunology and Cell Biology 78, no. 3 (June 2000): 224-237. Full Text
  - Owen, JA, van der Keyl, H, and Gellad, Z. "Disparity between the time of onset of heavy and light chain hypermutation." FASEB JOURNAL 13, no. 5 (March 15, 1999): A990-A990. Link to Item
- Conference Papers
  - Finn, RT, Lloyd, B, Patel, Y, Allen, JT, Burr, N, Cornejo, J, Davis, A, Evans, L, McIntosh, T, Macy, S, Simms, K, Sudaj, S, Taheri, J, and Gellad, ZF. "Improving Endoscopy Access for Veterans: A Lean Performance Improvement Project Decreases Endoscopy No-Show Rate at a Veterans Affairs Hospital." : Elsevier BV, July 2018. Full Text
  - Charles, K, Sullivan, B, McIntosh, T, Gellad, ZF, Shimpi, RA, Gyawali, CP, and Patel, A. "ESOPHAGEAL BASELINE IMPEDANCE FROM HIGH-RESOLUTION IMPEDANCE MANOMETRY (BI-HRIM) CORRELATES WITH MEAN NOCTURNAL BASELINE IMPEDANCE (MNBI) FROM PH-IMPEDANCE MONITORING ON AND OFF PROTON PUMP INHIBITOR THERAPY." Annual Meeting of the American-Society-for-Gastrointestinal-Endoscopy / Digestive Disease Week. Washington, DC. June 2, 2018 - June 5, 2018.: W B SAUNDERS CO-ELSEVIER INC, May 1, 2018. Link to Item
  - Finn, RT, Lloyd, B, Patel, YA, Cornejo, J, McIntosh, T, Allen, J, Davis, A, Macy, S, Sims, K, Burr, N, Taheri, J, Sudaj, S, and Gellad, ZF. "IMPROVING ENDOSCOPY ACCESS FOR VETERANS: A LEAN PERFORMANCE IMPROVEMENT PROJECT DECREASES ENDOSCOPY NO-SHOW RATE AT A VETERANS AFFAIRS HOSPITAL." Annual Meeting of the American-Society-for-Gastrointestinal-Endoscopy / Digestive Disease Week. Washington, DC. June 2, 2018 - June 5, 2018.: W B SAUNDERS CO-ELSEVIER INC, May 1, 2018. Link to Item
  - Leiman, DA, Jawitz, NG, Lin, L, Wood, RK, and Gellad, ZF. "TERMINAL ILEUM INTUBATION DOES NOT IMPROVE ADENOMA DETECTION RATE." Annual Meeting of the American-Society-for-Gastrointestinal-Endoscopy / Digestive Disease Week. Washington, DC. June 2, 2018 - June 5, 2018.: W B SAUNDERS CO-ELSEVIER INC, May 1, 2018. Link to Item
  - Qin, X, Hauser, ER, Stone, A, Carter, WC, Sims, K, Whitley, RL, Madison, A, O'Leary, MC, Redding, TS, Sullivan, B, Gellad, ZF, Musselwhite, L, Lieberman, DA, and Provenzale, D. "GENETIC ASSOCIATION ANALYSIS OF ADVANCED NEOPLASIA IN A COLON CANCER SCREENING COHORT." Annual Meeting of the American-Society-for-Gastrointestinal-Endoscopy / Digestive Disease Week. Washington, DC. June 2, 2018 - June 5, 2018.: W B SAUNDERS CO-ELSEVIER INC, May 1, 2018. Link to Item
  - Spechler, SJ, Lee, RH, Smith, BR, Mashimo, H, Sanchez, V, Dunbar, KB, Thai, P, Murthy, UK, Kim, T, Jackson, CS, Wallen, J, Von Rosenvinge, EC, Pearl, J, Laine, L, Kim, A, Kaz, AM, Tatum, R, Gellad, ZF, Deenadayalan, S, Rubenstein, JH, Ghaferi, A, Lo, W-K, Fernando, RS, Chan, BS, Paski, S, Provenzale, D, Castell, DO, Lieberman, DA, Souza, RF, Chey, WD, Warren, S, Karim, AD, Melton, S, Genta, RM, Jones, K, and Hunter, JG. "A VA COOPERATIVE, RANDOMIZED TRIAL OF MEDICAL AND SURGICAL TREATMENTS FOR PATIENTS WITH HEARTBURN THAT IS REFRACTORY TO PROTON PUMP INHIBITORS." Annual Meeting of the American-Society-for-Gastrointestinal-Endoscopy / Digestive Disease Week. Washington, DC. June 2, 2018 - June 5, 2018.: W B SAUNDERS CO-ELSEVIER INC, May 1, 2018. Link to Item
  - Spechler, SJ, Lee, RH, Smith, BR, Mashimo, H, Sanchez, V, Dunbar, KB, Thai, P, Murthy, UK, Kim, T, Jackson, CS, Wallen, J, Von Rosenvinge, EC, Pearl, J, Laine, L, Kim, A, Kaz, AM, Tatum, R, Gellad, ZF, Deenadayalan, S, Rubenstein, JH, Ghaferi, A, Lo, W-K, Fernando, RS, Chan, BS, Paski, S, Provenzale, D, Castell, DO, Lieberman, DA, Souza, RF, Chey, WD, Warren, S, Karim, AD, Melton, S, Genta, RM, Jones, K, and Hunter, JG. "CHARACTERIZATION OF CONDITIONS UNDERLYING HEARTBURN REFRACTORY TO PROTON PUMP INHIBITORS ( PPIS) IN A VA COOPERATIVE STUDY OF MEDICAL AND SURGICAL TREATMENTS FOR PPI- REFRACTORY HEARTBURN." Annual Meeting of the American-Society-for-Gastrointestinal-Endoscopy / Digestive Disease Week. Washington, DC. June 2, 2018 - June 5, 2018.: W B SAUNDERS CO-ELSEVIER INC, May 1, 2018. Link to Item
  - Sullivan, B, Redding, TS, Hauser, ER, Gellad, ZF, Qin, X, Gupta, S, Robertson, DJ, Weiss, DG, O'Leary, MC, Madison, A, Bullard, J, Hyslop, T, Musselwhite, L, Sims, K, Thomas, R, Williams, C, Hong, J, Johnson, M, Turner, M, Provenzale, D, and Lieberman, DA. "HIGH RISK ADENOMAS AT BASELINE COLONOSCOPY ASSOCIATED WITH FUTURE ADVANCED ADENOMA DESPITE AN INTERVENING NEGATIVE COLONOSCOPY." Annual Meeting of the American-Society-for-Gastrointestinal-Endoscopy / Digestive Disease Week. Washington, DC. June 2, 2018 - June 5, 2018.: W B SAUNDERS CO-ELSEVIER INC, May 1, 2018. Link to Item
  - Voils, C, King, H, Blalock, D, Thorpe, CT, Kronish, I, Reeve, B, Hunt, CM, Boatright, C, Bolton, J, and Gellad, ZF. "CHARACTERIZING ADHERENCE TO DIRECT-ACTING ANTIVIRAL TREATMENT FOR HEPATITIS C INFECTION." Annual Meeting of the American-Society-for-Gastrointestinal-Endoscopy / Digestive Disease Week. Washington, DC. June 2, 2018 - June 5, 2018.: W B SAUNDERS CO-ELSEVIER INC, May 1, 2018. Link to Item
  - Gellad, Z, Chermak, D, Brown, E, and Taheri, J. "Automating Endoscopy Unit Efficiency Metrics: Leveraging the Electronic Health Record for Process Improvement." May 2015. Link to Item
  - Gellad, Z, Burchfield, D, Cooper, K, and Taheri, J. "Impact of Propofol on Endoscopy Unit Efficiency: A Discrete Event Simulation Model." October 2013. Link to Item
  - Gellad, ZF, Taheri, J, Burchfield, D, Cooper, K, Lothrop, S, and AL-Kawas, FH. "Discrete Event Simulation Modeling: A Valuable Tool to Optimize Endoscopy Unit Efficiency." April 2012. Link to Item
  - Gellad, ZF, Naggie, S, Reed, SD, Clark, PJ, Thompson, AJ, Schulman, KA, and Muir, AJ. "THE COST-EFFECTIVENESS OF A TELAPREVIR-INCLUSIVE REGIMEN AS INITIAL THERAPY FOR GENOTYPE 1 HEPATITIS C INFECTION IN INDIVIDUALS WITH THE CC IL-28B POLYMORPHISM." October 2011. Link to Item
  - Gellad, ZF, Reed, S, Muir, AJ, McHutchison, J, Steven, W, Sharara, AI, Brown, KAA, Flisiak, R, Jacobson, IM, Kershenobich, D, Manns, MP, and Schulman, KA. "Truncated Therapy Based on Rapid Virologic Response is a Cost Effective Treatment Paradigm for Chronic Hepatitis C." May 2011. Link to Item
Scholarly, Clinical, & Service Activities
Service to the Profession
- Chair, Quality Measures Committee. American Gastroenterological Association. 2014 - 2017 2014 - 2017
Academic & Administrative Activities
- 2017 -              Associate vice Chair for Clinical Innovation, Department of Medicine
  
  2016 -              Duke Connected Care (ACO) Operating Committee
  
  2014 -             Director of Quality, Division of Gastroenterology
  
  2014 - 2017      Director of Clinical Improvement, Department of Medicine
  
  2014 - 2017      Chair, Management of Information Committee, Durham VA Medical Center
  
  2013 - 2014      Project Lead, Enterprise Wide Planning, Duke Medicine
  
  2012 - 2013      Faculty Lead, Duke Institute for Health Innovation Planning Committee

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Education, Training, & Certifications

Duke Appointment History

Subject Headings

Selected Grants

Fellowships, Supported Research, & Other Grants

Selected Publications

Academic Articles

Conference Papers

Service to the Profession

Academic & Administrative Activities