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Routing-aware resource allocation for mixture preparation in digital microfluidic biochips

Publication ,  Journal Article
Roy, S; Chakrabarti, PP; Kumar, S; Bhattacharya, BB; Chakrabarty, K
Published in: Proceedings of IEEE Computer Society Annual Symposium on VLSI, ISVLSI
January 1, 2013

On-chip mixing of several biochemical fluids with a specified ratio of concentration factors is a challenging problem in automating biochemical laboratory protocols on a digital microfluidic biochip. The performance of a mixing algorithm depends on resource allocation, e.g., the placement of mixer modules, storage units, boundary reservoirs or dispensers on the chip floor. With a limited number of resources, mixing of a large number of fluids may be slowed down because of the stalls arising out of fluidic constraints during droplet transportation. In this paper, we propose a routing-aware resource allocation technique which can be adopted with two basic mixing algorithms. Simulation results show that on an average, the proposed scheme can reduce the number of droplet crossing paths by 75.4% or by 89.7%, depending on the underlying basic algorithm used for mixture preparation. © 2013 IEEE.

Published In

Proceedings of IEEE Computer Society Annual Symposium on VLSI, ISVLSI

DOI

EISSN

2159-3477

ISSN

2159-3469

Publication Date

January 1, 2013

Start / End Page

165 / 170
 

Citation

APA
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MLA
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Roy, S., Chakrabarti, P. P., Kumar, S., Bhattacharya, B. B., & Chakrabarty, K. (2013). Routing-aware resource allocation for mixture preparation in digital microfluidic biochips. Proceedings of IEEE Computer Society Annual Symposium on VLSI, ISVLSI, 165–170. https://doi.org/10.1109/ISVLSI.2013.6654653
Roy, S., P. P. Chakrabarti, S. Kumar, B. B. Bhattacharya, and K. Chakrabarty. “Routing-aware resource allocation for mixture preparation in digital microfluidic biochips.” Proceedings of IEEE Computer Society Annual Symposium on VLSI, ISVLSI, January 1, 2013, 165–70. https://doi.org/10.1109/ISVLSI.2013.6654653.
Roy S, Chakrabarti PP, Kumar S, Bhattacharya BB, Chakrabarty K. Routing-aware resource allocation for mixture preparation in digital microfluidic biochips. Proceedings of IEEE Computer Society Annual Symposium on VLSI, ISVLSI. 2013 Jan 1;165–70.
Roy, S., et al. “Routing-aware resource allocation for mixture preparation in digital microfluidic biochips.” Proceedings of IEEE Computer Society Annual Symposium on VLSI, ISVLSI, Jan. 2013, pp. 165–70. Scopus, doi:10.1109/ISVLSI.2013.6654653.
Roy S, Chakrabarti PP, Kumar S, Bhattacharya BB, Chakrabarty K. Routing-aware resource allocation for mixture preparation in digital microfluidic biochips. Proceedings of IEEE Computer Society Annual Symposium on VLSI, ISVLSI. 2013 Jan 1;165–170.

Published In

Proceedings of IEEE Computer Society Annual Symposium on VLSI, ISVLSI

DOI

EISSN

2159-3477

ISSN

2159-3469

Publication Date

January 1, 2013

Start / End Page

165 / 170