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Automatic grid fitting for genetic spot array images containing guide spots

Publication ,  Conference
Brändle, N; Lapp, H; Bischof, H
Published in: Lecture Notes in Computer Science Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics
January 1, 1999

In the domain of biotechnology array-based methods are used to gain rapid access to genetic information based on the signals of the individual array elements (spots). For an automated analysis of the spots it is necessary to fit a grid to the spots in the digital image in order to represent the array distortions that may occur in the course of the experiment. In order to make the grid fitting problem tractable in a certain class of experiments spot arrays contain a sub-grid of guide spots with a known signal characteristic. We present an automatic grid fitting method for spot array images containing guide spots. Our approach uses simple image processing methods and takes into account prior knowledge inherent in the imaging process.

Duke Scholars

Published In

Lecture Notes in Computer Science Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics

DOI

EISSN

1611-3349

ISSN

0302-9743

Publication Date

January 1, 1999

Volume

1689

Start / End Page

357 / 366

Related Subject Headings

  • Artificial Intelligence & Image Processing
  • 46 Information and computing sciences
 

Citation

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MLA
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Brändle, N., Lapp, H., & Bischof, H. (1999). Automatic grid fitting for genetic spot array images containing guide spots. In Lecture Notes in Computer Science Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics (Vol. 1689, pp. 357–366). https://doi.org/10.1007/3-540-48375-6_43
Brändle, N., H. Lapp, and H. Bischof. “Automatic grid fitting for genetic spot array images containing guide spots.” In Lecture Notes in Computer Science Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics, 1689:357–66, 1999. https://doi.org/10.1007/3-540-48375-6_43.
Brändle N, Lapp H, Bischof H. Automatic grid fitting for genetic spot array images containing guide spots. In: Lecture Notes in Computer Science Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics. 1999. p. 357–66.
Brändle, N., et al. “Automatic grid fitting for genetic spot array images containing guide spots.” Lecture Notes in Computer Science Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics, vol. 1689, 1999, pp. 357–66. Scopus, doi:10.1007/3-540-48375-6_43.
Brändle N, Lapp H, Bischof H. Automatic grid fitting for genetic spot array images containing guide spots. Lecture Notes in Computer Science Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics. 1999. p. 357–366.

Published In

Lecture Notes in Computer Science Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics

DOI

EISSN

1611-3349

ISSN

0302-9743

Publication Date

January 1, 1999

Volume

1689

Start / End Page

357 / 366

Related Subject Headings

  • Artificial Intelligence & Image Processing
  • 46 Information and computing sciences