Skip to main content
Journal cover image

Capsule endoscopy performed across the pediatric age range: indications, incomplete studies, and utility in management of inflammatory bowel disease.

Publication ,  Journal Article
Jensen, MK; Tipnis, NA; Bajorunaite, R; Sheth, MK; Sato, TT; Noel, RJ
Published in: Gastrointest Endosc
July 2010

BACKGROUND: Capsule endoscopy (CE) is used increasingly to evaluate the small bowel in children. An upper GI series is recommended before CE to evaluate the risk of obstruction. Despite normal findings on an upper GI series, CE may still be incomplete. Although large adult studies have demonstrated the safety and diagnostic yield of CE, similar pediatric studies have not been available. OBJECTIVE: To identify factors associated with incomplete studies and the diagnostic yield in pediatric patients. DESIGN: Retrospective review of consecutive CE studies from February 2005 through June 2008. SETTING: Large tertiary children's hospital. PATIENTS: A total of 123 CE studies in 117 patients; median age 12.9 years (range 0.8-22.4 years). MAIN OUTCOME MEASUREMENTS: Demographic information, indication, placement technique, pre-CE imaging results, and cecal completion status were recorded. Risk factors were analyzed with bivariate and multivariate regression analysis. RESULTS: There were 27 (22%) incomplete studies; of these, there were normal pre-CE radiologic study findings in 12 (44%), and findings requiring medical, endoscopic, or operative intervention in 6. Of the 117 patients, CE produced a new diagnosis in 21 (18%). Abnormal findings on previous imaging (odds ratio [OR] 3.0; 95% CI, 1.2-8.0), endoscopic placement (OR 3.1; 95% CI, 1.1-8.4), and female sex (OR 3.3; 95% CI, 1.2-9.4) were associated with incomplete studies. LIMITATIONS: Retrospective, incomplete follow-up. CONCLUSIONS: CE may be performed in children as small as 11.5 kg, with 18% yield in all studies, and 28% in pediatric known inflammatory bowel disease. Capsule retention requiring retrieval did not pose life-threatening risk in our series, and CE may be used to identify disease-associated small-bowel stenosis.

Duke Scholars

Published In

Gastrointest Endosc

DOI

EISSN

1097-6779

Publication Date

July 2010

Volume

72

Issue

1

Start / End Page

95 / 102

Location

United States

Related Subject Headings

  • Young Adult
  • Thrombocytopenia
  • Risk Factors
  • Retrospective Studies
  • Regression Analysis
  • Male
  • Lymphangioma
  • Intestinal Obstruction
  • Infant
  • Humans
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Jensen, M. K., Tipnis, N. A., Bajorunaite, R., Sheth, M. K., Sato, T. T., & Noel, R. J. (2010). Capsule endoscopy performed across the pediatric age range: indications, incomplete studies, and utility in management of inflammatory bowel disease. Gastrointest Endosc, 72(1), 95–102. https://doi.org/10.1016/j.gie.2010.01.016
Jensen, M Kyle, Neelesh A. Tipnis, Ruta Bajorunaite, Mehul K. Sheth, Thomas T. Sato, and Richard J. Noel. “Capsule endoscopy performed across the pediatric age range: indications, incomplete studies, and utility in management of inflammatory bowel disease.Gastrointest Endosc 72, no. 1 (July 2010): 95–102. https://doi.org/10.1016/j.gie.2010.01.016.
Jensen MK, Tipnis NA, Bajorunaite R, Sheth MK, Sato TT, Noel RJ. Capsule endoscopy performed across the pediatric age range: indications, incomplete studies, and utility in management of inflammatory bowel disease. Gastrointest Endosc. 2010 Jul;72(1):95–102.
Jensen, M. Kyle, et al. “Capsule endoscopy performed across the pediatric age range: indications, incomplete studies, and utility in management of inflammatory bowel disease.Gastrointest Endosc, vol. 72, no. 1, July 2010, pp. 95–102. Pubmed, doi:10.1016/j.gie.2010.01.016.
Jensen MK, Tipnis NA, Bajorunaite R, Sheth MK, Sato TT, Noel RJ. Capsule endoscopy performed across the pediatric age range: indications, incomplete studies, and utility in management of inflammatory bowel disease. Gastrointest Endosc. 2010 Jul;72(1):95–102.
Journal cover image

Published In

Gastrointest Endosc

DOI

EISSN

1097-6779

Publication Date

July 2010

Volume

72

Issue

1

Start / End Page

95 / 102

Location

United States

Related Subject Headings

  • Young Adult
  • Thrombocytopenia
  • Risk Factors
  • Retrospective Studies
  • Regression Analysis
  • Male
  • Lymphangioma
  • Intestinal Obstruction
  • Infant
  • Humans