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Infectious aortitis and spondylodiscitis in patients with endovascular stents.

Publication ,  Journal Article
d'Ettorre, G; Ceccarelli, G; Zaffiri, L; Falcone, M; Mastroianni, CM; Venditti, M; Vullo, V
Published in: Minerva Med
April 2009

The infection of endovascular stents remains one of the most problematic complications of aortic surgery. This article describes the case of a 61-year-old male with ascendant and descendent aorta endovascular stents, hospitalized for pyrexia, weight loss and back pain. Blood culture was positive for Staphylococcus hominis resistant to oxacillin and ciprofloxacin. Spiral computed tomography, magnetic resonance imaging and leukocyte-labelled scintigraphy showed that the patient developed a perigraft infection which spondylodiscitis in correspondence of D7, D8 and D9 vertebras. The biopsy CT-scan guided of vertebral inflammed tissue revealed a coagulase-negative Staphylo-coccus and the presence of numerous neutrophilis granulocytes. The reintervention for substituting an infected graft was excluded due to the high risk of death or paraplegia. A therapy with vancomycin, rifampicin and ceftazidime was started. On the basis of clinical and radiological findings, it was decided to switch empirical antimicrobial therapy to levofloxacin, minocycline and teicoplanin and a reduction of inflammation indices was observed. The patient was discharged maintaining this chronic suppressive antimicrobial therapy with a 28-day cycle of linezolid with complete regression of pain, and normalization of inflammation blood indices. After, therapy switched to teicoplanin three times a week while maintaining good clinical and radiological features. In the present, due to the high risk in performing a surgical procedure, a conservative chronic suppressive antimicrobial therapy with teicoplanin allowed to control the infection on an outpatient basis, thereby reducing the costs.

Duke Scholars

Published In

Minerva Med

ISSN

0026-4806

Publication Date

April 2009

Volume

100

Issue

2

Start / End Page

167 / 170

Location

Italy

Related Subject Headings

  • Stents
  • Staphylococcus hominis
  • Staphylococcal Infections
  • Reoperation
  • Prosthesis-Related Infections
  • Prosthesis Implantation
  • Middle Aged
  • Male
  • Humans
  • General & Internal Medicine
 

Citation

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ICMJE
MLA
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d’Ettorre, G., Ceccarelli, G., Zaffiri, L., Falcone, M., Mastroianni, C. M., Venditti, M., & Vullo, V. (2009). Infectious aortitis and spondylodiscitis in patients with endovascular stents. Minerva Med, 100(2), 167–170.
Ettorre, G. d’, G. Ceccarelli, L. Zaffiri, M. Falcone, C. M. Mastroianni, M. Venditti, and V. Vullo. “Infectious aortitis and spondylodiscitis in patients with endovascular stents.Minerva Med 100, no. 2 (April 2009): 167–70.
d’Ettorre G, Ceccarelli G, Zaffiri L, Falcone M, Mastroianni CM, Venditti M, et al. Infectious aortitis and spondylodiscitis in patients with endovascular stents. Minerva Med. 2009 Apr;100(2):167–70.
d’Ettorre, G., et al. “Infectious aortitis and spondylodiscitis in patients with endovascular stents.Minerva Med, vol. 100, no. 2, Apr. 2009, pp. 167–70.
d’Ettorre G, Ceccarelli G, Zaffiri L, Falcone M, Mastroianni CM, Venditti M, Vullo V. Infectious aortitis and spondylodiscitis in patients with endovascular stents. Minerva Med. 2009 Apr;100(2):167–170.

Published In

Minerva Med

ISSN

0026-4806

Publication Date

April 2009

Volume

100

Issue

2

Start / End Page

167 / 170

Location

Italy

Related Subject Headings

  • Stents
  • Staphylococcus hominis
  • Staphylococcal Infections
  • Reoperation
  • Prosthesis-Related Infections
  • Prosthesis Implantation
  • Middle Aged
  • Male
  • Humans
  • General & Internal Medicine