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Fructose metabolism and metabolic disease.

Publication ,  Journal Article
Hannou, SA; Haslam, DE; McKeown, NM; Herman, MA
Published in: J Clin Invest
February 1, 2018

Increased sugar consumption is increasingly considered to be a contributor to the worldwide epidemics of obesity and diabetes and their associated cardiometabolic risks. As a result of its unique metabolic properties, the fructose component of sugar may be particularly harmful. Diets high in fructose can rapidly produce all of the key features of the metabolic syndrome. Here we review the biology of fructose metabolism as well as potential mechanisms by which excessive fructose consumption may contribute to cardiometabolic disease.

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Published In

J Clin Invest

DOI

EISSN

1558-8238

Publication Date

February 1, 2018

Volume

128

Issue

2

Start / End Page

545 / 555

Location

United States

Related Subject Headings

  • Sugars
  • Risk Factors
  • Metabolic Syndrome
  • Liver
  • Immunology
  • Hypertension
  • Humans
  • Glucose Transporter Type 2
  • Glucose
  • Gene Expression Profiling
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Hannou, S. A., Haslam, D. E., McKeown, N. M., & Herman, M. A. (2018). Fructose metabolism and metabolic disease. J Clin Invest, 128(2), 545–555. https://doi.org/10.1172/JCI96702
Hannou, Sarah A., Danielle E. Haslam, Nicola M. McKeown, and Mark A. Herman. “Fructose metabolism and metabolic disease.J Clin Invest 128, no. 2 (February 1, 2018): 545–55. https://doi.org/10.1172/JCI96702.
Hannou SA, Haslam DE, McKeown NM, Herman MA. Fructose metabolism and metabolic disease. J Clin Invest. 2018 Feb 1;128(2):545–55.
Hannou, Sarah A., et al. “Fructose metabolism and metabolic disease.J Clin Invest, vol. 128, no. 2, Feb. 2018, pp. 545–55. Pubmed, doi:10.1172/JCI96702.
Hannou SA, Haslam DE, McKeown NM, Herman MA. Fructose metabolism and metabolic disease. J Clin Invest. 2018 Feb 1;128(2):545–555.

Published In

J Clin Invest

DOI

EISSN

1558-8238

Publication Date

February 1, 2018

Volume

128

Issue

2

Start / End Page

545 / 555

Location

United States

Related Subject Headings

  • Sugars
  • Risk Factors
  • Metabolic Syndrome
  • Liver
  • Immunology
  • Hypertension
  • Humans
  • Glucose Transporter Type 2
  • Glucose
  • Gene Expression Profiling