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A Brief History of the β-Arrestins.

Publication ,  Journal Article
Caron, MG; Barak, LS
Published in: Methods Mol Biol
2019

Arrestins have now been implicated in the actions of virtually every G protein-coupled receptor (GPCR) for which they have been examined. Originally discovered for their role in the turnoff of visual perception, their newly discovered pleotropic functions in the cellular and physiological actions of GPCRs not only illuminate new mechanisms of signal transduction but also offer new avenues for therapeutic utility. Below, in this introductory chapter, we provide a short historical description and synopsis of how arrestins conceptually became associated with the function of GPCRs.

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Published In

Methods Mol Biol

DOI

EISSN

1940-6029

Publication Date

2019

Volume

1957

Start / End Page

3 / 8

Location

United States

Related Subject Headings

  • beta-Arrestins
  • Humans
  • History, 20th Century
  • Developmental Biology
  • Animals
  • 3404 Medicinal and biomolecular chemistry
  • 3101 Biochemistry and cell biology
  • 0601 Biochemistry and Cell Biology
  • 0399 Other Chemical Sciences
 

Citation

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Caron, M. G., & Barak, L. S. (2019). A Brief History of the β-Arrestins. Methods Mol Biol, 1957, 3–8. https://doi.org/10.1007/978-1-4939-9158-7_1
Caron, Marc G., and Lawrence S. Barak. “A Brief History of the β-Arrestins.Methods Mol Biol 1957 (2019): 3–8. https://doi.org/10.1007/978-1-4939-9158-7_1.
Caron MG, Barak LS. A Brief History of the β-Arrestins. Methods Mol Biol. 2019;1957:3–8.
Caron, Marc G., and Lawrence S. Barak. “A Brief History of the β-Arrestins.Methods Mol Biol, vol. 1957, 2019, pp. 3–8. Pubmed, doi:10.1007/978-1-4939-9158-7_1.
Caron MG, Barak LS. A Brief History of the β-Arrestins. Methods Mol Biol. 2019;1957:3–8.

Published In

Methods Mol Biol

DOI

EISSN

1940-6029

Publication Date

2019

Volume

1957

Start / End Page

3 / 8

Location

United States

Related Subject Headings

  • beta-Arrestins
  • Humans
  • History, 20th Century
  • Developmental Biology
  • Animals
  • 3404 Medicinal and biomolecular chemistry
  • 3101 Biochemistry and cell biology
  • 0601 Biochemistry and Cell Biology
  • 0399 Other Chemical Sciences