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Outcomes of Adult Patients with Small Body Size Supported with a Continuous-Flow Left Ventricular Assist Device.

Publication ,  Journal Article
Lee, S; Katz, JN; Jorde, UP; Moazami, N; John, R; Sundareswaran, KS; Farrar, DJ; Frazier, OH
Published in: Asaio J
2016

There is insufficient data on patients with small body size to determine if this should be considered a risk factor for continuous-flow left ventricular assist device (CF-LVAD) support. We sought to evaluate survival outcomes, adverse events, and functional status of CF-LVAD patients with body surface area (BSA) <1.5 m in a large national registry. Adults with BSA < 1.5 m (n = 128) implanted with a HeartMate II (HMII)-LVAD from the Interagency Registry for Mechanically Assisted Circulatory Support registry from April 2008 to December 2012 formed this cohort. Outcomes were compared with HMII bridge to transplant (BTT) and destination therapy (DT) post approval studies. The majority of patients were female (n = 106, 83%). A total of 64% (n = 82) were implanted for BTT and 36% (n = 46) for DT. The median BSA (range) was 1.44 (1.19-1.49) and 1.45 (1.25-1.49) m for BTT and DT, respectively. Overall survival 1 year post implant was 81% ± 5% for BTT and 84% ± 6% for DT. The most common adverse events for BTT and DT patients were bleeding (0.91, 0.88 events/patient year) and driveline infection (16%, 0.28 events/patient year). Six months post implantation, 87% of BTT and 77% of DT patients were New York Heart Association functional class I or II. Post implant survival, functional status improvement, and adverse event profile for adult BTT and DT HMII patients with BSA < 1.5 m are favorable and comparable with outcomes published in the overall patient population.

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Published In

Asaio J

DOI

EISSN

1538-943X

Publication Date

2016

Volume

62

Issue

6

Start / End Page

646 / 651

Location

United States

Related Subject Headings

  • Registries
  • Middle Aged
  • Male
  • Humans
  • Heart-Assist Devices
  • Heart Failure
  • Female
  • Body Size
  • Biomedical Engineering
  • Aged
 

Citation

APA
Chicago
ICMJE
MLA
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Lee, S., Katz, J. N., Jorde, U. P., Moazami, N., John, R., Sundareswaran, K. S., … Frazier, O. H. (2016). Outcomes of Adult Patients with Small Body Size Supported with a Continuous-Flow Left Ventricular Assist Device. Asaio J, 62(6), 646–651. https://doi.org/10.1097/MAT.0000000000000430
Lee, Sangjin, Jason N. Katz, Ulrich P. Jorde, Nader Moazami, Ranjit John, Kartik S. Sundareswaran, David J. Farrar, and O. H. Frazier. “Outcomes of Adult Patients with Small Body Size Supported with a Continuous-Flow Left Ventricular Assist Device.Asaio J 62, no. 6 (2016): 646–51. https://doi.org/10.1097/MAT.0000000000000430.
Lee S, Katz JN, Jorde UP, Moazami N, John R, Sundareswaran KS, et al. Outcomes of Adult Patients with Small Body Size Supported with a Continuous-Flow Left Ventricular Assist Device. Asaio J. 2016;62(6):646–51.
Lee, Sangjin, et al. “Outcomes of Adult Patients with Small Body Size Supported with a Continuous-Flow Left Ventricular Assist Device.Asaio J, vol. 62, no. 6, 2016, pp. 646–51. Pubmed, doi:10.1097/MAT.0000000000000430.
Lee S, Katz JN, Jorde UP, Moazami N, John R, Sundareswaran KS, Farrar DJ, Frazier OH. Outcomes of Adult Patients with Small Body Size Supported with a Continuous-Flow Left Ventricular Assist Device. Asaio J. 2016;62(6):646–651.

Published In

Asaio J

DOI

EISSN

1538-943X

Publication Date

2016

Volume

62

Issue

6

Start / End Page

646 / 651

Location

United States

Related Subject Headings

  • Registries
  • Middle Aged
  • Male
  • Humans
  • Heart-Assist Devices
  • Heart Failure
  • Female
  • Body Size
  • Biomedical Engineering
  • Aged