Histone Lactylation: A New Role for Glucose Metabolism.
Publication
, Journal Article
Liberti, MV; Locasale, JW
Published in: Trends Biochem Sci
March 2020
Lactate is an end product of glucose metabolism, which serves metabolic and nonmetabolic functions. A new study by Zhang et al. establishes a novel function for lactate whereby it is utilized in a new histone modification, histone lysine lactylation, to regulate gene expression in macrophages.
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Published In
Trends Biochem Sci
DOI
ISSN
0968-0004
Publication Date
March 2020
Volume
45
Issue
3
Start / End Page
179 / 182
Location
England
Related Subject Headings
- Macrophages
- Lysine
- Histones
- Glucose
- Gene Expression
- Developmental Biology
- 11 Medical and Health Sciences
- 06 Biological Sciences
- 03 Chemical Sciences
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Liberti, M. V., & Locasale, J. W. (2020). Histone Lactylation: A New Role for Glucose Metabolism. Trends Biochem Sci, 45(3), 179–182. https://doi.org/10.1016/j.tibs.2019.12.004
Liberti, Maria V., and Jason W. Locasale. “Histone Lactylation: A New Role for Glucose Metabolism.” Trends Biochem Sci 45, no. 3 (March 2020): 179–82. https://doi.org/10.1016/j.tibs.2019.12.004.
Liberti MV, Locasale JW. Histone Lactylation: A New Role for Glucose Metabolism. Trends Biochem Sci. 2020 Mar;45(3):179–82.
Liberti, Maria V., and Jason W. Locasale. “Histone Lactylation: A New Role for Glucose Metabolism.” Trends Biochem Sci, vol. 45, no. 3, Mar. 2020, pp. 179–82. Pubmed, doi:10.1016/j.tibs.2019.12.004.
Liberti MV, Locasale JW. Histone Lactylation: A New Role for Glucose Metabolism. Trends Biochem Sci. 2020 Mar;45(3):179–182.
Published In
Trends Biochem Sci
DOI
ISSN
0968-0004
Publication Date
March 2020
Volume
45
Issue
3
Start / End Page
179 / 182
Location
England
Related Subject Headings
- Macrophages
- Lysine
- Histones
- Glucose
- Gene Expression
- Developmental Biology
- 11 Medical and Health Sciences
- 06 Biological Sciences
- 03 Chemical Sciences