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Anti-Vascular Endothelial Growth Factor Therapy for Radiation Retinopathy.

Publication ,  Journal Article
Rayess, N; Mruthyunjaya, P
Published in: Ophthalmic Surg Lasers Imaging Retina
April 1, 2020

BACKGROUND AND OBJECTIVE: The purpose of this article is to review the role of anti-vascular endothelial growth factor (VEGF) therapy in treating patients with radiation retinopathy (RR). PATIENTS AND METHODS: RR can be associated with a significant decrease in visual acuity (VA) related to the development of cystoid macular edema, macular ischemia, and proliferative retinopathy leading to neovascular glaucoma. RESULTS: Anti-VEGF therapy is effective at stabilizing VA in around 80% of patients and achieving reductions in central macular thickness when it is administered using a constant algorithm. Furthermore, consistent prophylactic anti-VEGF therapy reduces the risk of development of RR, neovascularization of the iris, and neovascularization glaucoma. CONCLUSION: Future studies are needed to determine the optimal regimen for anti-VEGF therapy according to patient risk factors and likelihood of developing RR. [Ophthalmic Surg Lasers Imaging Retina. 2020;51:S44-S49.].

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Published In

Ophthalmic Surg Lasers Imaging Retina

DOI

EISSN

2325-8179

Publication Date

April 1, 2020

Volume

51

Issue

4

Start / End Page

S44 / S49

Location

United States

Related Subject Headings

  • Visual Acuity
  • Vascular Endothelial Growth Factor A
  • Tomography, Optical Coherence
  • Retinal Diseases
  • Retina
  • Radiation Injuries
  • Intravitreal Injections
  • Humans
  • Angiogenesis Inhibitors
 

Citation

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Rayess, N., & Mruthyunjaya, P. (2020). Anti-Vascular Endothelial Growth Factor Therapy for Radiation Retinopathy. Ophthalmic Surg Lasers Imaging Retina, 51(4), S44–S49. https://doi.org/10.3928/23258160-20200401-06
Rayess, Nadim, and Prithvi Mruthyunjaya. “Anti-Vascular Endothelial Growth Factor Therapy for Radiation Retinopathy.Ophthalmic Surg Lasers Imaging Retina 51, no. 4 (April 1, 2020): S44–49. https://doi.org/10.3928/23258160-20200401-06.
Rayess N, Mruthyunjaya P. Anti-Vascular Endothelial Growth Factor Therapy for Radiation Retinopathy. Ophthalmic Surg Lasers Imaging Retina. 2020 Apr 1;51(4):S44–9.
Rayess, Nadim, and Prithvi Mruthyunjaya. “Anti-Vascular Endothelial Growth Factor Therapy for Radiation Retinopathy.Ophthalmic Surg Lasers Imaging Retina, vol. 51, no. 4, Apr. 2020, pp. S44–49. Pubmed, doi:10.3928/23258160-20200401-06.
Rayess N, Mruthyunjaya P. Anti-Vascular Endothelial Growth Factor Therapy for Radiation Retinopathy. Ophthalmic Surg Lasers Imaging Retina. 2020 Apr 1;51(4):S44–S49.

Published In

Ophthalmic Surg Lasers Imaging Retina

DOI

EISSN

2325-8179

Publication Date

April 1, 2020

Volume

51

Issue

4

Start / End Page

S44 / S49

Location

United States

Related Subject Headings

  • Visual Acuity
  • Vascular Endothelial Growth Factor A
  • Tomography, Optical Coherence
  • Retinal Diseases
  • Retina
  • Radiation Injuries
  • Intravitreal Injections
  • Humans
  • Angiogenesis Inhibitors