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Proteomics in uveal melanoma.

Publication ,  Journal Article
Heiferman, MJ; Mahajan, VB; Mruthyunjaya, P
Published in: Current opinion in ophthalmology
May 2022

This article reviews the latest proteomic research on uveal melanoma.Proteomic analysis of uveal melanoma cell lines and tissue specimens has improved our understanding of the pathophysiology of uveal melanoma and helped identify potential prognostic biomarkers. Circulating proteins in patient serum may aid in the surveillance of metastatic disease. The proteomes of aqueous and vitreous biopsy specimens may provide safer biomarkers for metastatic risk and candidate therapeutic targets in uveal melanoma. Proteomic analysis has the potential to benefit patient outcomes by improving diagnosis, prognostication, surveillance, and treatment of uveal melanoma.These recent findings demonstrate that proteomic analysis is an important area of research to better understand the pathophysiology of uveal melanoma and improve the personalized management of our patients.

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Published In

Current opinion in ophthalmology

DOI

EISSN

1531-7021

ISSN

1040-8738

Publication Date

May 2022

Volume

33

Issue

3

Start / End Page

202 / 210

Related Subject Headings

  • Uveal Neoplasms
  • Proteomics
  • Ophthalmology & Optometry
  • Melanoma
  • Humans
  • Biopsy
  • 3212 Ophthalmology and optometry
  • 1113 Opthalmology and Optometry
 

Citation

APA
Chicago
ICMJE
MLA
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Heiferman, M. J., Mahajan, V. B., & Mruthyunjaya, P. (2022). Proteomics in uveal melanoma. Current Opinion in Ophthalmology, 33(3), 202–210. https://doi.org/10.1097/icu.0000000000000835
Heiferman, Michael J., Vinit B. Mahajan, and Prithvi Mruthyunjaya. “Proteomics in uveal melanoma.Current Opinion in Ophthalmology 33, no. 3 (May 2022): 202–10. https://doi.org/10.1097/icu.0000000000000835.
Heiferman MJ, Mahajan VB, Mruthyunjaya P. Proteomics in uveal melanoma. Current opinion in ophthalmology. 2022 May;33(3):202–10.
Heiferman, Michael J., et al. “Proteomics in uveal melanoma.Current Opinion in Ophthalmology, vol. 33, no. 3, May 2022, pp. 202–10. Epmc, doi:10.1097/icu.0000000000000835.
Heiferman MJ, Mahajan VB, Mruthyunjaya P. Proteomics in uveal melanoma. Current opinion in ophthalmology. 2022 May;33(3):202–210.

Published In

Current opinion in ophthalmology

DOI

EISSN

1531-7021

ISSN

1040-8738

Publication Date

May 2022

Volume

33

Issue

3

Start / End Page

202 / 210

Related Subject Headings

  • Uveal Neoplasms
  • Proteomics
  • Ophthalmology & Optometry
  • Melanoma
  • Humans
  • Biopsy
  • 3212 Ophthalmology and optometry
  • 1113 Opthalmology and Optometry