Skip to main content
Journal cover image

Displacement of submacular hemorrhage with intravitreal tissue plasminogen activator following 27 gauge transvitreal fine needle aspiration biopsy for choroidal melanoma.

Publication ,  Journal Article
Narala, R; Bodnar, Z; Mruthyunjaya, P
Published in: Am J Ophthalmol Case Rep
March 2022

PURPOSE: To describe the management of submacular hemorrhage (SMH), a vision threatening complication following transvitreal choroidal biopsy, with intravitreal tissue plasminogen activator (tPA) and pure perfluoropropane (C3F8) gas bubble injection. OBSERVATIONS: A 53 year old female with choroidal melanoma of the left eye underwent iodine-125 plaque brachytherapy placement and 27 gauge transvitreal fine needle aspiration choroidal biopsy for gene expression profiling. On postoperative day 2, large SMH was identified on dilated fundus examination. At the time of plaque brachytherapy removal, intravitreal tPA and pure C3F8 gas bubble injection with post operative positioning was also performed to attempt displacement of SMH. At postoperative month 1 following tPA and gas bubble displacement, the SMH was completely displaced inferotemporally outside of the macula and visual acuity improved from 20/70 at postoperative week 1 to 20/25 at postoperative month 1. CONCLUSIONS AND IMPORTANCE: Subretinal hemorrhage can be a complication of transvitreal choroidal tumor biopsy but early detection and prompt treatment can result in good visual outcomes.

Duke Scholars

Published In

Am J Ophthalmol Case Rep

DOI

EISSN

2451-9936

Publication Date

March 2022

Volume

25

Start / End Page

101320

Location

United States
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Narala, R., Bodnar, Z., & Mruthyunjaya, P. (2022). Displacement of submacular hemorrhage with intravitreal tissue plasminogen activator following 27 gauge transvitreal fine needle aspiration biopsy for choroidal melanoma. Am J Ophthalmol Case Rep, 25, 101320. https://doi.org/10.1016/j.ajoc.2022.101320
Narala, Ramsudha, Zachary Bodnar, and Prithvi Mruthyunjaya. “Displacement of submacular hemorrhage with intravitreal tissue plasminogen activator following 27 gauge transvitreal fine needle aspiration biopsy for choroidal melanoma.Am J Ophthalmol Case Rep 25 (March 2022): 101320. https://doi.org/10.1016/j.ajoc.2022.101320.
Narala, Ramsudha, et al. “Displacement of submacular hemorrhage with intravitreal tissue plasminogen activator following 27 gauge transvitreal fine needle aspiration biopsy for choroidal melanoma.Am J Ophthalmol Case Rep, vol. 25, Mar. 2022, p. 101320. Pubmed, doi:10.1016/j.ajoc.2022.101320.
Journal cover image

Published In

Am J Ophthalmol Case Rep

DOI

EISSN

2451-9936

Publication Date

March 2022

Volume

25

Start / End Page

101320

Location

United States