Scholars@Duke

The Stanley Foundation Bipolar Network. I. Rationale and methods.

Publication ,  Conference
Post, RM; Nolen, WA; Kupka, RW; Denicoff, KD; Leverich, GS; Keck, PE; McElroy, SL; Rush, AJ; Suppes, T; Altshuler, LL; Frye, MA; Grunze, H; Walden, J
Published in: Br J Psychiatry Suppl
June 2001
Published version (DOI) Link to item

BACKGROUND: The Stanley Foundation Bipolar Network (SFBN) was created to address the paucity of help studies in bipolar illness. AIMS: To describe the rationale and methods of the SFBN. METHOD: The SFBN includes five core sites and a number of affiliated sites that have adopted consistent methodology for continuous longitudinal monitoring of patients. Open and controlled studies are performed as patients' symptomatology dictates. RESULTS: The reliability of SFBN raters and the validity of the rating instruments have been established. More than 500 patients are in continuous daily longitudinal follow-up. More than 125 have been randomised to one of three of the newer antidepressants (bupropion, sertraline and venlafaxine) as adjuncts in a study of mood stabilizers and 93 to omega-3 fatty acids. A number of open clinical case series have been published. CONCLUSIONS: Well-characterised patients are followed in a detailed continuous longitudinal fashion in both opportunistic case series and double-blind, randomised controlled trials with reliable and validated measures.

Duke Scholars

Augustus John Rush
Author Augustus John Rush Psychiatry & Behavioral Sciences, Behavioral Medicine & Neur ...

Published In

Br J Psychiatry Suppl

DOI

10.1192/bjp.178.41.s169

ISSN

0960-5371

Publication Date

June 2001

Volume

41

Start / End Page

s169 / s176

Location

England

Related Subject Headings

  • Research Design
  • Randomized Controlled Trials as Topic
  • Psychiatry
  • Multicenter Studies as Topic
  • Longitudinal Studies
  • Humans
  • Bipolar Disorder
  • Antimanic Agents
  • 52 Psychology
  • 42 Health sciences
 

Citation

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MLA
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Post, R. M., Nolen, W. A., Kupka, R. W., Denicoff, K. D., Leverich, G. S., Keck, P. E., … Walden, J. (2001). The Stanley Foundation Bipolar Network. I. Rationale and methods. In Br J Psychiatry Suppl (Vol. 41, pp. s169–s176). England. https://doi.org/10.1192/bjp.178.41.s169
Post, R. M., W. A. Nolen, R. W. Kupka, K. D. Denicoff, G. S. Leverich, P. E. Keck, S. L. McElroy, et al. “The Stanley Foundation Bipolar Network. I. Rationale and methods.” In Br J Psychiatry Suppl, 41:s169–76, 2001. https://doi.org/10.1192/bjp.178.41.s169.
Post RM, Nolen WA, Kupka RW, Denicoff KD, Leverich GS, Keck PE, et al. The Stanley Foundation Bipolar Network. I. Rationale and methods. In: Br J Psychiatry Suppl. 2001. p. s169–76.
Post, R. M., et al. “The Stanley Foundation Bipolar Network. I. Rationale and methods.” Br J Psychiatry Suppl, vol. 41, 2001, pp. s169–76. Pubmed, doi:10.1192/bjp.178.41.s169.
Post RM, Nolen WA, Kupka RW, Denicoff KD, Leverich GS, Keck PE, McElroy SL, Rush AJ, Suppes T, Altshuler LL, Frye MA, Grunze H, Walden J. The Stanley Foundation Bipolar Network. I. Rationale and methods. Br J Psychiatry Suppl. 2001. p. s169–s176.

Published In

Br J Psychiatry Suppl

DOI

10.1192/bjp.178.41.s169

ISSN

0960-5371

Publication Date

June 2001

Volume

41

Start / End Page

s169 / s176

Location

England

Related Subject Headings

  • Research Design
  • Randomized Controlled Trials as Topic
  • Psychiatry
  • Multicenter Studies as Topic
  • Longitudinal Studies
  • Humans
  • Bipolar Disorder
  • Antimanic Agents
  • 52 Psychology
  • 42 Health sciences