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[Vagus nerve stimulation. A potential therapy for chronic/recurrent depression?].

Publication ,  Journal Article
Rush, AJ; Linden, M; Zobel, A
Published in: Fortschr Neurol Psychiatr
June 2002

Vagus Nerve Stimulation (VNS) is since the 1990 a clinically useful anticonvulsant therapy for treatment-resistant epilepsy. Open acute and longer term data suggest the potential clinical utility of VNS as an antidepressant therapy especially in treatment refractory depression. The vagus nerve has connections to the limbic system and other brain structures which modulate affect. PET studies showed functional changes under VNS in such critical areas, which can explain the mechanisms of action of VMS. Ongoing studies will have to better establish its acute and longer-term efficacy, and specific indications in the treatment of depression.

Duke Scholars

Published In

Fortschr Neurol Psychiatr

DOI

ISSN

0720-4299

Publication Date

June 2002

Volume

70

Issue

6

Start / End Page

297 / 302

Location

Germany

Related Subject Headings

  • Vagus Nerve
  • Psychiatry
  • Humans
  • Electrodes, Implanted
  • Electric Stimulation Therapy
  • Depressive Disorder
  • 1109 Neurosciences
  • 1103 Clinical Sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Rush, A. J., Linden, M., & Zobel, A. (2002). [Vagus nerve stimulation. A potential therapy for chronic/recurrent depression?]. Fortschr Neurol Psychiatr, 70(6), 297–302. https://doi.org/10.1055/s-2002-32022
Rush, A. J., M. Linden, and A. Zobel. “[Vagus nerve stimulation. A potential therapy for chronic/recurrent depression?].Fortschr Neurol Psychiatr 70, no. 6 (June 2002): 297–302. https://doi.org/10.1055/s-2002-32022.
Rush AJ, Linden M, Zobel A. [Vagus nerve stimulation. A potential therapy for chronic/recurrent depression?]. Fortschr Neurol Psychiatr. 2002 Jun;70(6):297–302.
Rush, A. J., et al. “[Vagus nerve stimulation. A potential therapy for chronic/recurrent depression?].Fortschr Neurol Psychiatr, vol. 70, no. 6, June 2002, pp. 297–302. Pubmed, doi:10.1055/s-2002-32022.
Rush AJ, Linden M, Zobel A. [Vagus nerve stimulation. A potential therapy for chronic/recurrent depression?]. Fortschr Neurol Psychiatr. 2002 Jun;70(6):297–302.
Journal cover image

Published In

Fortschr Neurol Psychiatr

DOI

ISSN

0720-4299

Publication Date

June 2002

Volume

70

Issue

6

Start / End Page

297 / 302

Location

Germany

Related Subject Headings

  • Vagus Nerve
  • Psychiatry
  • Humans
  • Electrodes, Implanted
  • Electric Stimulation Therapy
  • Depressive Disorder
  • 1109 Neurosciences
  • 1103 Clinical Sciences