Supplementary Figure S1 from EGFR Inhibition by Cetuximab Modulates Hypoxia and IFN Response Genes in Head and Neck Squamous Cell Carcinoma

<p>(A, B) Heatmap of molecular subgroups in two different HNSCC datasets (A) TCGA and (B) CPTAC. RNA expression data was z-normalized, each row represents a single gene in the hypoxia-immune signature gene list, each column represents a patient sample. Samples were reordered according to its molecular subgroup: Immune (blue), Mixture (black) and Hypoxia (red). (C) Kaplan–Meier survival plots for overall survival stratified according to the hypoxia-immune signature for TCGA (n = 518) HNSCC patient cohorts.</p>

Duke Scholars

Author Jose Ramon Conejo-Garcia Integrative Immunobiology