Supplementary Figure S1 from Epidermal growth factor receptor inhibition by cetuximab modulates hypoxia and interferon response genes in head and neck squamous cell carcinoma

<p>(A, B) Heatmap of molecular subgroups in two different HNSCC datasets (A) TCGA and (B) CPTAC. RNA expression data was z-normalized, each row represents a single gene in the hypoxia-immune signature gene list, each column represents a patient sample. Samples were reordered according to its molecular subgroup: Immune (blue), Mixture (black) and Hypoxia (red). (C) Kaplan–Meier survival plots for overall survival stratified according to the hypoxia-immune signature for TCGA (n = 518) HNSCC patient cohorts. </p>

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Author Jose Ramon Conejo-Garcia Integrative Immunobiology